A Method For Determining A Volume Of A Dye Used For Obtaining A Medical Image And A System Thereof


Updated about 2 years ago

Abstract

The invention explains a method for determining a volume of adye used for obtaining a medical image (504) of a vessel of apatient during a medical procedure. The method involves,receiving a medical image (504) of the vessel obtained duringthe medical procedure and identifying at least one anatomicalfeature (518) of the medical image. The method alsoessentially involves receiving at least one demographicinformation (516) of the patient and further determining thevolume of dye based on the anatomical feature (518) and thedemographic information (516).

Information

Application ID 1094/KOL/2010
Invention Field BIO-MEDICAL ENGINEERING
Date of Application 2010-09-29
Publication Number 42/2012

Applicants

Name Address Country Nationality
SIEMENS AKTIENGESELLSCHAFT WITTELSBACHERPLATZ 2 80333 MÜNCHEM GERMANY Germany Germany

Inventors

Name Address Country Nationality
RAJENDRA PRASAD JADIYAPPA INDIA CITIZEN, I MAIN, 11A CROSS,WOC II STAGE, MAHALAXMIPURAM, 560086 BANGALORE, INDIA, KARNATAKA India India

Specification

Description
A. method for determining a volume of a dye used for obtaining
a medical image and a system thereof
The present invention relates to a method and system for
determining a volume of a dye administered to a vessel of a
patient for obtaining a medical image of the vessel during a
medical procedure.
The volume of dye required for obtaining a medical image of a
vessel in different parts of the patient need to be
quantified for analytical as well as for safety reasons.
Depending on the anatomical nature of the organ or its parts,
there is a minimum volume of dye which needs to be injected
to these regions for obtaining a medical image. At the same
time, the volume of dye injected to these regions should be
within acceptable limits so as to avoid any harmful effects
of the dye on these organs, since excess of dye can cause
irreparable damages to said organ or to the kidneys.
Although differences in the volume of dye which need to be
injected have been recognized based on the anatomical
structure, conventional procedures for obtaining a medical
image continue to use pre-set volumes of dye during medical
procedures.
Dye is commonly used in medical procedures, for example in
coronary angiography, left ventriculography and aortography.
The dye is used for imaging anatomical structures to enable
diagnosis and also for performing medical procedure steps
which involves cannulation and interventions. The dye
injected into a patient is ultimately excreted by the
kidneys. In some cases, if excess of dye is injected into the
body it causes kidney dysfunction and heart failure.
Currently it is a challenging task to accurately measure the
quantity of dye that is used in a particular patient during a
medical procedure.

The currently available quantitative analytical method for
finding the amount of dye injected in a patient is based on
calculating the utilization of number of fixed volume dye
bottles and on the used dye in the last bottle at the end of
the medical procedure. However this is a cumbersome and a
slow process and it is not possible to calculate the precise
volume of dye injected, more so in cases where the volume in
bottle varies and also during the course of the medical
procedure.
Hence there is a need for a fast and accurate method to
determine the volume of dye used for obtaining a medical
image.
The said object is achieved by a method for determining a
volume of a dye used according to claim 1 and by a system
according to claim 11.
The underlying idea is to determine the volume of dye used
for obtaining a medical image of a vessel based on the
anatomical feature and the demographic information. The
determination of the volume of the dye becomes fast since the
method identifies the anatomical feature from the medical
image of the vessel soon after the medical image is received.
The demographical information of the patient influences the
volume of dye used for obtaining the medical image. Hence,
combining demographic information and anatomical feature will
result in a more accurate determination of the volume of dye.
In a preferred embodiment, the volume of dye is determined
from a database, which contains data representing a
relationship between the anatomical feature and the
demographic information on the one hand side and the volume
of dye on the other hand side. The use of such a database for
the determination of the volume of the dye helps to provide
more accurate and realistic data without much delay.
In another embodiment, the method further comprises
indicating the volume of the dye. The indication of the
volume of the dye enables the user of said method to obtain

and understand the volume of dye used for obtaining a medical
image of the vessel and further enables to regulate the
volume of dye injection for further image acquisitions.
In another embodiment, the anatomical feature of the medical
image includes a type of an organ which is represented in the
medical image. The type of the organ increases the
specificity for the determination of the volume of the dye;
for example to target a vessel which supplies blood to the
heart, the type of the organ would be the heart.
In another embodiment, the anatomical feature of the medical
image includes a size of the organ. The size of the organ
further increases the specificity for the determination of
the volume of the dye.
In another optional combination the type and the size of the
organ enables to identify the volume of the dye from the
database more accurately, since the retrieved information
from the database corresponds to the information provided to
the database. The more precise the information provided to
the database the more accurate will be the retrieved results.
In another embodiment, the demographic information of the
patient is selected from a group consisting of age, sex,
height and weight of the patient. The volume of dye required
to capture a similar anatomical structure changes based on
the age, gender, height and weight of the patient. The said
demographic information further increases the specificity and
the accuracy for the determination of the volume of the dye.
The information on the volume of dye used for obtaining a
medical image of a vessel might be stored in the database
based on different demographic information of the patient. In
another optional combination, providing said demographic
information to the method helps to quickly and accurately
obtain the volume of dye for imaging the vessel from a
database.

In another embodiment, the method further comprises providing
the type of the medical procedure for determining the volume
of dye. The volume of dye used for obtaining images for
different type of medical procedure varies. Hence, providing
the type of medical procedure provide additional accuracy in
the determination of the volume of the dye. For example, the
type of medical procedure could be coronary angiography, left
ventriculography or aortography.
In another embodiment, the method further comprises providing
the type of the medical procedure step for determining the
volume of dye. It is recognized that, the volume of dye used
for obtaining images for different type of medical procedure
steps vary. Hence, providing the type of the medical
procedure step enables to provide additional accuracy in the
determination of the volume of the dye.
In another embodiment, the medical procedure steps is
selected from a group consisting of cannulation, acquisition,
intervention and automatic injection from an injector. The
said medical procedures further increase the specificity for
the determination of the volume of the dye.
The invention also relates to a method of determining a total
volume of dye used for obtaining a plurality of medical
images of a vessel of a patient during a medical procedure
which comprises, receiving the plurality of medical images
during a medical procedure, determining an individual volume
of dye used for obtaining each of the plurality of individual
medical images and summing the individual volumes of the dye
to determine the total volume of dye. If there are multiple
images obtained during a medical procedure, the volume of dye
used for these images can be determined by summing the volume
of dye used for obtaining individual images. This will
provide the total volume of the dye used for the whole
medical procedure.
The invention also related to a system for determining a
volume of a dye used for imaging a vessel of a patient during
a medical procedure. The said system comprising a memory for

storing a medical image of the vessel; an interface for
receiving at least one demographic information, of the
patient; a processor for identifying at least one anatomical
feature of the medical image and determining the volume of
dye based on the anatomical feature and the demographic
information. The system determines a volume of a dye used for
imaging a vessel using demographic information which the
interface has received and using the anatomical feature
identified by the processor.
In another embodiment the system further comprises a
database, which contains data representing a relationship
between the anatomical feature and the demographic
information on the one hand side and the volume of dye on the
other hand side, and a data connection from the database to
the processor for determining the volume of dye via the data
stored in the database. The use of such a database for the
determination of the volume of the dye helps to provide more
accurate and realistic data without much delay.
In another embodiment the system further has a display for
indicating the volume of dye. The display helps to visualize,
for example the volume of dye, enabling the user of the
system to make inferences and conclusions on the status of
the used dye in the patient.
The present invention is further described hereinafter with
reference to illustrated embodiments shown in the
accompanying drawings, in which:
FIG 1 illustrates a flow chart showing a method for
determining a volume of a dye used for obtaining a medical
image of a vessel of a patient,
FIG 2 illustrates a flow chart showing a method for
determining a volume of a dye used for obtaining a medical
image of a vessel of a patient by the use of a database and
by the use of a function,

FIG 3 illustrates a block diagram for determining a total
volume of dye used for obtaining a plurality of medical
images of a vessel of a patient during a medical procedure,
FIG 4 illustrates a block diagram for determining a total
volume of dye used in a medical procedure which comprises of
plurality of medical procedure steps, and
FIG 5 illustrates a block diagram of a system for determining
a volume of a dye used for obtaining a medical image of a
vessel.
FIG 1 illustrates a flow chart 100 showing a method for
determining a volume of a dye used for obtaining a medical
image of a vessel of a patient. At step 102, the method
involves receiving a medical image of the vessel obtained
during the medical procedure. An appropriate medical image of
the vessel is obtained by an imaging modality, for example
using an X-ray based device.
At step 104, at least one anatomical feature of the medical
image is identified by the method from the medical image. The
anatomical feature of the medical image includes type of an
organ or size of the organ which is represented in the
medical image. Any known image recognition algorithm can be
used for identifying an anatomical feature.
At step 106, at least one demographic information of the
patient is received. The demographic information of the
patient can be the age, gender, height and weight of the
patient. The amount of dye used for imaging an organ of a
child would not be the same for a fully grown adult.
At step 108, the volume of dye used for obtaining a medical
image of a vessel is determined based on the anatomical
feature and the demographic information.
FIG 2 illustrates a flow chart 200 showing a method for
determining a volume of a dye used for obtaining a medical
image of a vessel of a patient by the use of a database and

by the use of a functional relationship. The method steps
201, 202 and 203 of receiving a medical image, identifying at
least one anatomical feature and receiving at least one
demographic information of the patient respectively is
similar to that explained in FIG 1.
At step 204, the method chooses whether to determine the
volume of the dye using a functional relationship or by using
a database.
At step 206, the volume of dye for imaging the vessel is
determined using a functional relationship that exist between
the anatomical feature, the demographic information and the
volume of the dye. Based on the historical information an
appropriate functional relationship can be established.
At step 207, the volume of dye for imaging the vessel is
determined from a database based on the anatomical feature
and the demographic information. The database has got
realistic historical information on the volume of dye used on
different patients and their body parts. This information is
stored in the database in a structured manner. For example
the information on the volume of dye used for imaging can be
stored based on but not limited to the organ type or based on
the demographic information of the patient.
The type and/or size of an organ, which is an anatomical
feature of the medical image, enable fast and accurate
identification of the corresponding information from the
database. For example, if the organ in the medical image is a
heart with its coronary artery then the method can obtain the
information on the volume of dye for imaging coronary artery
from the database. For example, in the database the
information on the volume of dye for imaging coronary will be
stored under Coronary Angiography image information.
At step 208, the volume of the dye used for imaging the
vessel is indicated. This information which is obtained from
the database will be a very close approximation of the actual
amount of dye used for the imaging.

FIG 3 illustrates a flow chart 300 of a method for
determining a total volume of dye used for obtaining a
plurality of medical images of a vessel of a patient during a
medical procedure. The method involves receiving the
plurality of medical images during a medical procedure
according to step 302. At step 304 an individual volume of
dye used for obtaining each of the plurality of individual
medical images is determined. The volume of dye used for
individual medical images are determined similarly as
explained in the FIG 1. At step 306 the volumes of the dye
used for the individual medical images are added up to
determine the total volume of dye used for obtaining the
image during a medical procedure.
FIG 4 illustrates a block diagram 400 for determining a total
volume of dye used in a medical procedure which comprises of
plurality of medical procedure steps. The medical procedure
steps could include cannulation, acquisition, intervention
and automatic injection from an injector. For example, a
medical procedure like coronary angiography involves multiple
medical procedure steps.
Initially, the medical procedure includes cannulation to
reach the corresponding coronary artery which involves the
use of dye. The volume 4 02 of the dye is the required amount
of dye used for the cannulation. Then images are acquired
after injecting the dye to identify the exact location of a
problem. The volume 404 of the dye used for the acquisition
is obtained from the database based on the anatomical feature
of the medical image and the demographic information of the
patient as described accordingly with respect to FIG 2
database. To perform the medical procedure the physician
might also use automated injector to inject the dye for
obtaining more medical images. The volume 406 is the amount
of dye injected using a dye injector. Finally the procedure
might end up by performing an interventional procedure for
example, Coronary Angioplasty with stenting. This might also
require a specific volume of dye for obtaining the
appropriate medical images for performing intervention and
analysis. The volume 408 of the dye represents the volume of

dye used for intervention. All the dye volumes are added up
to determine the total volume 410 of the dye required for the
whole medical procedure. The total volume of the dye used at
any point in time can be determined by adding the amount of
dye used for the medical procedure done till that point in
time.
FIG 5 illustrates a block diagram of a system 500 for
determining a volume of a dye used for obtaining a medical
image of a vessel in a patient. The system 500 comprises a
memory 502 for storing a received medical image 504 of the
vessel. An interface 506 is used for receiving at least one
demographic information 516 of the patient. The interface 506
can be a computer console. For example, a physician can type
the patient demographic information using the console. A
processor 508 identifies at least one anatomical feature 518
of the medical image 504. The processor can further use a
function 512 or use a database 514 to determine the volume of
dye based on the anatomical feature 518 and the demographic
information 516. A display 510 is used for indicating the
volume of the dye used for imaging the vessel. The display
can be a computer display.
The database 514 is a structured database where the
information on the volume of dye used for obtaining an image
is stored. For example, the data is categorized and stored in
the database based on the demographic information 516 and
anatomical feature 518 of the image. The data in the database
can also be stored based on the medical procedure. The data
in the database represents a relationship between the
anatomical feature 518 and the demographic information 516 on
the one hand side and the volume of dye on the other hand
side. The data in the database 514 can be realistic
historical data which were obtained during an earlier
performed medical procedure or medical procedure step on
different category of patients. The database 514 consists of
a data connection from the database 514 to the processor 508
for determining the volume of dye via the data stored in the
database 514.

The method for determining a volume of a dye used for
obtaining a medical image can be implemented on a computer
and hence the invention can also be realized as a computer
readable medium with executable software code which, when
executed on a computer, performed the method, based on the
interaction with the physician.
Although the invention has been described with reference to
specific embodiments, this description is not meant to be
construed in a limiting sense. Various modifications of the
disclosed embodiments, as well as alternate embodiments of
the invention, will become apparent to persons skilled in the
art upon reference to the description of the invention. It is
therefore contemplated that such modifications can be made
without departing from the embodiments of the present
invention as defined.

WE CLAIM
1. A method for determining a volume of a dye used for
obtaining a medical image (504) of a vessel of a patient
during a medical procedure comprising:
- receiving a medical image (504) of the vessel obtained
during the medical procedure;
- identifying at least one anatomical feature (518) of the
medical image;
- receiving at least one demographic information (516) of the
patient;
- determine the volume of dye based on the anatomical feature
(518) and the demographic information (516).
2. The method according to claim 1, wherein the volume of dye
is determined from a database (514), which contains data
representing a relationship between the anatomical feature
(518) and the demographic information (516) on the one hand
side and the volume of dye on the other hand side.
3. The method according to any of the preceding claims,
further comprising indicating the volume of the dye.
4. The method according to any of the preceding claims,
wherein the anatomical feature (518) of the medical image
(504) includes type of an organ which is represented in the
medical image (504).
5. The method according to any of the preceding claims,
wherein the anatomical feature (518) of the medical image
includes size of the organ.
6. The method according to any of the preceding claims,
wherein the demographic information (516) of the patient is
selected from a group consisting of age, sex, height and
weight of the patient.
7. The method according to any of the preceding claims,
further comprises providing the type of the medical procedure
for determining the volume of dye.

8. The method according to any of the preceding claims,
further comprises providing the type of the medical procedure
step for determining the volume of dye.
9. The method according to any of the preceding claims,
wherein the medical procedure step is selected from a group
consisting of cannulation, acquisition, intervention and
automatic injection from an injector.
10. A method of determining a total volume of dye used for
obtaining a plurality of medical images (504) of a vessel of
a patient during a medical procedure comprising:
- receiving the plurality of medical images (504) during a
medical procedure;
- determining an individual volume of dye used for obtaining
each of the plurality of individual medical images (504) with
the method according to any of the preceding claims; and
- summing the individual volumes of the dye to determine the
total volume of dye.
11. A system for determining a volume of a dye used for
imaging a vessel of a patient during a medical procedure
comprising:
- a memory (502) for storing a medical image (504) of the
vessel;
- an interface (506) for receiving at least one demographic
information (516) of the patient;
- a processor (508) for identifying at least one anatomical
feature (518) of the medical image (504) and determining the
volume of dye based on the anatomical feature (518) and the
demographic information (516).
12. The system according to claim 11, further comprising:
- a database (514), which contains data representing a
relationship between the anatomical feature (518) and the
demographic information (516) on the one hand side and the
volume of dye on the other hand side, and
- a data connection from the database (514) to the processor
(508) for determining the volume of dye via the data stored
in the database (514).

13. The system according the claim 11 or 12, further
comprising a display (510) for indicating the volume of dye.
14. The system according to any of the claims 11 to 13,
wherein the system is adapted to perform the method according
to any of the claims 1 to 10.

The invention explains a method for determining a volume of a
dye used for obtaining a medical image (504) of a vessel of a
patient during a medical procedure. The method involves,
receiving a medical image (504) of the vessel obtained during
the medical procedure and identifying at least one anatomical
feature (518) of the medical image. The method also
essentially involves receiving at least one demographic
information (516) of the patient and further determining the
volume of dye based on the anatomical feature (518) and the
demographic information (516).

Documents

Name Date
abstract-1094-kol-2010.jpg 2011-10-07
1094-kol-2010-form-3.pdf 2011-10-07
1094-kol-2010-form-2.pdf 2011-10-07
1094-kol-2010-gpa.pdf 2011-10-07
1094-kol-2010-specification.pdf 2011-10-07
1094-kol-2010-drawings.pdf 2011-10-07
1094-kol-2010-correspondence.pdf 2011-10-07
1094-KOL-2010-FORM 18.pdf 2011-10-07
1094-kol-2010-form-1.pdf 2011-10-07
1094-kol-2010-abstract.pdf 2011-10-07
1094-KOL-2010-FER.pdf 2017-06-07
1094-kol-2010-claims.pdf 2011-10-07
1094-KOL-2010-FER_SER_REPLY [04-12-2017(online)].pdf 2017-12-04
1094-KOL-2010-OTHERS [04-12-2017(online)].pdf 2017-12-04
1094-KOL-2010-DRAWING [04-12-2017(online)].pdf 2017-12-04
1094-kol-2010-description (complete).pdf 2011-10-07
1094-KOL-2010-PETITION UNDER RULE 137 [19-12-2017(online)].pdf 2017-12-19
1094-KOL-2010-ABSTRACT [04-12-2017(online)].pdf 2017-12-04
1094-KOL-2010-FORM 4(ii) [05-12-2017(online)].pdf 2017-12-05
1094-KOL-2010-CLAIMS [04-12-2017(online)].pdf 2017-12-04
1094-KOL-2010-HearingNoticeLetter.pdf 2019-03-19
1094-KOL-2010-US(14)-ExtendedHearingNotice-(HearingDate-01-07-2020).pdf 2020-06-01
1094-KOL-2010-COMPLETE SPECIFICATION [04-12-2017(online)].pdf 2017-12-04
1094-KOL-2010-Proof of Right (MANDATORY) [19-12-2017(online)].pdf 2017-12-19
1094-KOL-2010-Correspondence to notify the Controller [30-06-2020(online)].pdf 2020-06-30
1094-KOL-2010-Written submissions and relevant documents (MANDATORY) [26-04-2019(online)].pdf 2019-04-26
1094-KOL-2010-Written submissions and relevant documents [16-07-2020(online)].pdf 2020-07-16
1094-KOL-2010-FORM-26 [30-06-2020(online)].pdf 2020-06-30
1094-KOL-2010-FORM-24 [30-09-2020(online)].pdf 2020-09-30
1094-KOL-2010-RELEVANT DOCUMENTS [30-09-2020(online)].pdf 2020-09-30

Orders

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