1. FIELD OF INVENTION

A NOVEL FORMULATION FOR ANTI INFLAMMATION CONTAINING CURCUMIN AND GINGER

BACKGROUND OF THE INVENTION

An inflammation in any part of the body is characterized by swelling, pain, wound or loss of action of that particular part. There are many biological factors that are responsible for inducing inflammation in the body. Prostaglandins, Interleukins like ILl, IL6, IL8 and ILl2, Glutamate, etc are the important chemical agents that lead to pain. The common inflammatory disease include arthritis which include osteo arthritis, rheumatoid arthritis etc. The way by NSAID works is by inhibiting the growth of factors that cause pain. The trend of natural products with biological efficacy for treating inflammation is increasing day by day. The major advantage of natural products is that they don't have toxic effects. Turmeric the golden spice has many health benefits. Another natural compound with such medicinal properties is ginger. This fact sheet focuses on the use of bioavailable curcumin, the active component of turmeric and gingerol of ginger for treating inflammation. The novel process of blending the components will result in a highly efficient natural formulation.

2. SUMMARY OF THE INVENTION

Turmeric, the golden spice poses potential health benefits because of the presence of valuable phytochemicals present in the compound. The important constituent of the turmeric include the so called curcuminoids, viz Curcumin, de methoxycurcumin and bis demethoxy curcumin. The curcuminoids will act in a similar way as similar to that of NSAID. They inhibit cyclooxygenase and lipoxygenase enzymes, the major inflammatory factors of the human body. The anti inflammatory properties of the curcumin can be attributed to their ability to quench the formation of free radicals and hindering tissue degeneration. Curcumin also inhibits the action of leukotrienes. Ginger also belongs to the same family of turmeric. The potential medicinal properties of the ginger are due to the presence of the non volatile components Gingerols and shogaols. Gingerols and shogaols contribute to the pungency of the product. There are mainly 4 gingerols and 2 shogaols in the raw material out of which 6-gingerol is the chief constituent. Studies have proven the potential use of gingerol for the treatment of arthritis. It can be attributed to the presence of a, (3 unsaturated ketone moiety. Gingerol, Shogaol, and other structurally-related substances in ginger inhibit prostaglandin and leukotriene biosynthesis through suppression of 5-lipoxygenase or prostaglandin synthetase. Additionally, they can also inhibit synthesis of pro¬inflammatory cytokines such as IL-1, TNF-a, and IL-8. In another investigation , Shogaol can down-regulate inflammatory iNOS and COX-2 gene expression.

3. DESCRIPTION OF THE INVENTION

The active compound curcumin contributes to most of the medicinal properties of the turmeric. The structure of curcumin is depicted below:
6- gingerol is the active compound responsible for the anti inflammatory properties of ginger.
The novel process of encapsulation of the two will help to increase the efficacy of the drug.
Ingredients used
Curcumin Gingerols.

Claim,

1.A novel formulation for anti inflammation containing curcumin and ginger

2.A product according to claim 1, for treating anti-inflammation

3.A product according to claim 1, for treating osteo arthritis.

4.A product according to claim 1, for treating rheumatoid arthritis