Abstract: Inflammatory diseases continue to be a worldwide disease happening to human individuals. The toxic effects of synthetic drugs led to the emergence of natural and effective drugs. Curcumin the active component of turmeric has become an important drug for the treatment of inflammatory diseases like arthritis. Another compound which occurs naturally in the joints is Hyaluronic acid. Our novel encapsulation of Bioavailable curcumin and hyaluronic acid makes the formulation an effective drug for the treatment of Inflammations.
1. FIELD OF INVENTION
A NOVEL FOR ANTIINFLAMMATION CONTAINING HYALURONIC ACID
BACK GROUND OF INVENTION
There are many inflammatory diseases happening to the human body. The factors causing inflammation can be of external and internal origin; Body messengers also play an important role in causing inflammation. An inflammation is characterized by swelling, pain, wound or loss of action of the body part. Synthetic drugs like NSAISD are available for the treatment. But long time consumption of the drugs can lead to many health problems including liver damage. Turmeric, the golden spice poses many health benefits. It can be attributed to the presence of so called active components Curcuminoids. Out of which, curcumin is the most effective one. The bioavailability of curcumin plays a major role in the efficacy of the drug. Our process involves the formulation of bioavailable Curcuminoids and hyaluronic acid. Hyaluronic acid works as a lubricant in the joints. The synergistic action of the two makes it an effective formulation for treatment of inflammatory diseases.
2. SUMMARY OF THE INVENTION
Turmeric is a spice that comes from the root Curcuma longa, a member of the ginger family, Zingiberaceae. In Ayurveda (Indian traditional medicine), turmeric has been used for its medicinal properties for various indications and through different routes of administration, including topically, orally, and by inhalation. Curcuminoids are components of turmeric, which include mainly curcumin (diferuloyl methane), demethoxycurcumin, and bisdemethoxycurcmin. The possible mechanism of action involves decreasing the catalytic activities of phospholipase A and phospholipase C thereby decreasing arachadonic acid release from cellular phospholipids. It also inhibits the cyclooxygenase activity. Hyaluronic acid (HA) is a naturally occurring high molecular weight biopolysacharide, which has important biological functions. It is found in most connective tissues and is particularly concentrated in synovial fluid, the vitreous fluid of the eye, umbilical cords and chicken combs. Hyaluronic acid (HA) is composed of disaccharide repeats of D-glucuronic acid (GlcUA) and N-acetyl glucosamine (GlcNAc) joined alternately by b-1, 3 and b-1, 4 glycosidic bonds to form highly polymerized molecules . The molecular weights of HA from different sources are highly variable, ranging from 104 to 107 Da. Because of their molecular complexity, the solutions show a high viscosity even at small concentrations. Thus almost all of the viscosity of the synovial fluid is due to the hyaluronic acid. In the human body, HA occurs in the salt hyaluronate form and is found in high concentrations in the skin, umbilical cord, and vitreous humor. This fact sheet focuses on using a novel blend of bioavailable curcumin and hyaluronic acid for inflammatory diseases with synergistic effects of both.
3. DESCRIPTION OF THE INVENTION
The process of novel encapsulating technology of bioavailable curcumin and Hyaluronic acid makes the formulation an effective drug for the treatment of inflammatory diseases. The structure of curcumin is depicted below:
The synergistic action of the two makes the formulation an effective drug.
Ingredients Used:
Curcumin Hyaluronic acid
Claim,
1. A novel for anti inflammation containing hyaluronic acid.
2. A product according to claim 1, for treating anti-inflammation.
3. A product according to claim 1, for treating joint pains.
4. A product according to claiml, for treating arthritis.
| # | Name | Date |
|---|---|---|
| 1 | 4442-CHE-2015 ABSTRACT 25-08-2015.pdf | 2015-08-25 |
| 1 | 4442-CHE-2015 FORM-2 25-08-2015.pdf | 2015-08-25 |
| 2 | 4442-CHE-2015 CLAIMS 25-08-2015.pdf | 2015-08-25 |
| 2 | 4442-CHE-2015 FORM-1 25-08-2015.pdf | 2015-08-25 |
| 3 | 4442-CHE-2015 DESCRIPTION (COMPLETE) 25-08-2015.pdf | 2015-08-25 |
| 4 | 4442-CHE-2015 CLAIMS 25-08-2015.pdf | 2015-08-25 |
| 4 | 4442-CHE-2015 FORM-1 25-08-2015.pdf | 2015-08-25 |
| 5 | 4442-CHE-2015 ABSTRACT 25-08-2015.pdf | 2015-08-25 |
| 5 | 4442-CHE-2015 FORM-2 25-08-2015.pdf | 2015-08-25 |