Navigation
Methods Of Treating P38 Kinase Associated Conditions And Pyrrolotriazine Compounds Useful As Kinase Inhibitors
Updated about 2 years ago
Abstract
Methods of treating one or more conditions associated with p38 kinase activity are disclosed comprising administering to a patient in need thereof at least one compound having the formula (I) ## STR1 ## or a pharmaceutically acceptable salt, prodrug , or solvate thereof, wherein R.sub.3 is hydrogen, methyl, perfluoromethyl, methoxy, halogen, cyano, or NH. sub.2, preferably methyl, and X,R.sub.1 through R.sub6 and Z are as described in the specification. advantageously the groups --ZR. sub.5 taken together comprise an --NH-substituted aryl.
Information
| Application ID | 471/MUMNP/2003 |
| Date of Application | 2003-05-02 |
| Publication Number | 04 |
Applicants
| Name | Address | Country | Nationality |
|---|---|---|---|
| BRISTOL-MYERS SQUIBB COMPANY | A DELAWARE CORPORATION OF LAWRENCEVILLE - PRINCETON RD., P. O. BOX 4000, PRINCETON, NEW JERSEY 08543 - 4000, UNITED STATES OF AMERICA. | U.S.A. | U.S.A. |
Inventors
| Name | Address | Country | Nationality |
|---|---|---|---|
| 1) KATERINA LEFTHERIS, 2) JOEL BARRISH, 3) JOHN HYNES, 4) STEPHEN T. WROBLESKI | A DELAWARE CORPORATION OF LAWRENCEVILLE - PRINCETON RD., P. O. BOX 4000, PRINCETON, NEW JERSEY 08543 - 4000, UNITED STATES OF AMERICA. | U.S.A. | U.S.A. |
Specification
METHODS OF TREATING p38 KINASE-ASSOCIATED CONDITIONS AND PYRROLOTRIAZINE COMPOUNDS USEFUL AS KINASE INHIBITORS
Documents
| Name | Date |
| 471-mumnp-2003-cancelled pages(8-8-2006).pdf | 2018-08-08 |
| 471-mumnp-2003-claims(granted)-(8-8-2006).pdf | 2018-08-08 |
| 471-mumnp-2003-correspondence(ipo)-(29-9-2006).pdf | 2018-08-08 |
| 471-mumnp-2003-form 1a(2-5-2003).pdf | 2018-08-08 |
| 471-mumnp-2003-form 2(granted)-(8-8-2006).pdf | 2018-08-08 |
| 471-mumnp-2003-form 3(1-5-2003).pdf | 2018-08-08 |
| 471-mumnp-2003-form 3(8-8-2006).pdf | 2018-08-08 |
| 471-mumnp-2003-form 5(1-5-2003).pdf | 2018-08-08 |
| 471-mumnp-2003-form-pct-ipea-409(8-8-2006).pdf | 2018-08-08 |
| 471-mumnp-2003-petition under rule 137(8-8-2006).pdf | 2018-08-08 |
| 471-mumnp-2003-petition under rule 138(8-8-2006).pdf | 2018-08-08 |
| 471-mumnp-2003-power of authority(8-8-2006).pdf | 2018-08-08 |
| in-pct-2001-00471-mum-claims(granted)-(28-9-2005).doc | 2018-08-08 |
| in-pct-2001-00471-mum-form 2(granted)-(28-9-2005).doc | 2018-08-08 |
| 471-mumnp-2003-correspondence(29-12-2006).pdf | 2006-12-29 |
| 471-mumnp-2003-form 13(29-12-2006).pdf | 2006-12-29 |
| 471-MUMNP-2003-CORRESPONDENCE(RENEWAL PAYMENT LETTER)-(06-12-2006).pdf | 2006-12-06 |
| 471-mumnp-2003-form 18(28-12-2005).pdf | 2005-12-28 |
Orders
| Applicant | Section | Controller | Decision Date | URL |