1. Field of Invention

A novel method for preparing Stabilized and Bio-available allicin 1%

BACKGROUND OF THE INVENTION:
Allicin from garlic (Allium sativum) has antibacterial, antifungal,. antiviral and antiprotozoal activity and responsible for many health benefits. Allicin is of increasing interest in the search for new nutraceutical ingredients and natural medicines. Allicin in its pure form was found to exhibit antibacterial activity against a wide range of Gram-negative and Gram-positive bacteria, including multidrug-resistant enterotoxicogenic strains of Escherichia coli, antifungal activity against Candida albicans and antiparasitic activity including some major human intestinal protozoan parasites such as Entamoeba histolytica and Giardia lamblia. The main antimicrobial effect of allicin is due to its chemical reaction with thiol groups of various enzymes, e.g. alcohol dehydrogenase, thioredoxin reductase, and RNA polymerase, which can affect essential metabolism of cysteine proteinase activity involved in the virulence of E. histolytica.

2. SUMMARY OF THE INVENTION:

The invention relates the stability of allicin by encapsulation with beta-cyclddextrin. Cyclodextrins are a family of cyclic oligosaccharides with a hydrophilic outer surface and a liphophilic central cavity. Cyclodextrin molecules are relatively large with a number of hydrogen donors and acceptors and, thus, in general they do not permeate liphophilic membranes. Cyclodextrins are widely used as 'molecular cages' in the pharmaceutical, food and cosmetic industries. Beta-Cyclodextrin is used as complexing agent to increase the aqueous solubility, bioavailability and stability. The allicin molecules can be entrapped in cyclodextrin liphophilic cage; hence the allicin-cyclodextrin matrix thus has more bio¬availability, solubility and stability.

3. DESCRIPTION OF THE INVENTION:
The structure of Allicin is depicted below:
The novel extraction process is mentioned below: .
Ingredients Used: Garlic Juice Extract Beta-cyclodextrin

I Claim,

1. A novel method for preparing Stabilized and Bio-available allicin 1%

2. A product according to claim 1 , for preparing stable Allicin 1%

3. A product according to claim 1 , which can be used for treating cholesterol

4. A product according to claim , which can be used for antibacterial activity.