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Novel Nutraceutical Product From Moringa Leaf

Abstract: Leaves of Moringa Oleifera have been traditionally used because of its potential health benefits. The leaf extract poses many valuable phytochemicals such as nitrile glycosides, Saponins, alkaloids, antioxidants, vitamins, minerals, proteins etc. Sometimes the leaves are referred to as nutritional dynamite. The presence of this valuable phytochemicals makes it an essential ingredient in many of the nutraceutical supplements. Supplementing leaf extract powder will help in treating male infertility and helps the body to fight against many of the pathogens and toxins attacking the body. Novel extraction method with hydro alcohol and encapsulation with maltodextrin helps to recover many of the active components from the leaves.

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Patent Information

Application #
Filing Date
04 February 2015
Publication Number
32/2016
Publication Type
INA
Invention Field
FOOD
Status
Email
Parent Application

Applicants

PLANT LIPIDS PRIVATE LIMITED
KOLENCHERY, COCHIN

Inventors

1. SREERAJ GOPI
PLANT LIPIDS PRIVATE LIMITED, KOLENCHERY, COCHIN
2. KARTHIK VARMA
PLANT LIPIDS PRIVATE LIMITED, KOLENCHERY, COCHIN
3. ROBIN GEORGE
PLANT LIPIDS PRIVATE LIMITED, KOLENCHERY, COCHIN

Specification

l.Field of the invention
NOVEL NUTRACEUTICAL PRODUCT FROM MORINGA LEAF
BACKGROUND OF THE INVENTION:
Male infertility and male sexual dysfunctions continues to be a lifestyle disease happening to male individuals. There are many factors responsible for such a body conditions. Clinical studies have shown that the number of individuals suffering from male infertility is increasing day by day. Male sexual dysfunctions will affect the family life of an individual. Dopamine plays a vital role in maintaining a healthy human fertility. The level of dopamine is an important factor that is responsible for a healthy sexual life. But in many cases the level of the dopamine gets reduced by body metabolic activities, there by the effecting improper sexual functioning of the body. The activity of Phosphodiesterase type 5(PDE5) and MAOB also determines the healthy sexual activity of the male. This fact sheet focuses on the use of Leaf extract of Moringa for treating male infertility and other body ailments.
2.SUMMARY OF THE INVENTION
The invention relates supplementing leaf extract powder of Moringa Oleifera for the treatment of male sexual disorders. Male infertility continues to be a common problem in a day to day life of male humans. There are many reasons for such a condition. The possible mechanism underlying the action of treating male infertility with Moringa leaf extract powder is mentioned below. One of the main factor responsible for male infertility is the activity of Phosphodiesterase type 5(PDE5). PDE 5 plays an important role on penile tumescence and intromission phase. PDE-5 is the enzyme contributing the important role on the hydrolysis of Guanosine 3'5'-cyclic monophosphate (cGMP), an important second messenger in

cellular signal transduction processes including the smooth muscle relaxation. The presence of PDE 5 in penile corpus cavernosum is already studied. The leaf extract powder has the ability to suppress the activity of PDE5 and thereby resulting in proper erection. Besides PDE 5 the available amount of dopamine also contributes to male fertility. It is reported that dopamine is mainly metabolized by MAOB . Anything which inhibits the MAOB activity will result in increase of free dopamine in the body. The leaf extract of Moringa has been found to poses this activity and thereby increasing the amount of dopamine and male fertility. The leaf extract is also found to be a good supplement for antidiabetic, anti inflammatory, cardiovascular etc.
3. DESCRIPTION OF THE INVENTION
Novel extraction method with hydro alcohol helps to recover many of the active components. Chemical analysis have identified many active components in the leaf extract. The leaf extract is found to poses the below mentioned active isolates which has got many medicinal properties.
In addition to these components the leaf extract also contain 3-O-glucoside and quercetin-3-0-(6"-malonyl-glucoside), and lower amounts of kaempferol-3-O-

glucoside and kaempferol-3-0-(6"-malonyl-glucoside), 3- caffeoylquinic acid and
5-caffeoylquinic acid. Leaves of the plant contains 4-(alpha-l-
rhamnopyranosyloxy)-benzylglucosinolate and three monoacetyl isomers of this
glucosinolate. Other components in the leaf extract are O ethyl- 4-(alpha-L-
rhamnosyloxy) benzyl carbamate 4(alpha-L- rhamnosyloxy)-benzyl
isothiocyanate, beta-sitosterol, glycerol-l-(9-octadecanoate), 3-0-(6'-0-oleoyl-
beta-D-glucopyranosyl)-betasitosterol and beta-sitosterol-3-O-beta-D-
glucopyranoside. These valuable phytochemicals makes Moringa Oleifera leaf extract powder a valuable nutraceutical supplement. The novel process of extraction is mentioned below:
Ingredients used:
Moringa Oleifera leaf extract
Malto dextrin

/ Claim,
1. A Novel nutraceutical product from moringa leaf
2. A product according to claim 1, which is a obtained by hydro- alcoholic extraction of moringa leaf powder.
3. A product according to claim 1, which can be used as an antioxidant.
4. A product according to claim 1, which can be used as male libido.
5. A product according to claim 1, which can be used as natural vitamin supplement.
6. A product according to claim 1, which can be used as a nutritional supplement.

Documents

Application Documents

# Name Date
1 541-CHE-2015 FORM-2 04-02-2015.pdf 2015-02-04
2 541-CHE-2015 FORM-1 04-02-2015.pdf 2015-02-04
3 541-CHE-2015 DESCRIPTION (COMPLETE) 04-02-2015.pdf 2015-02-04
4 541-CHE-2015 CLAIMS 04-02-2015.pdf 2015-02-04
5 541-CHE-2015 ABSTRACT 04-02-2015.pdf 2015-02-04