DESC:FORM 2

THE PATENTS ACT, 1970
(SECTION 39 OF 1970)
&
The Patents Rules, 2003

COMPLETE SPECIFICATION
(Section 10 and Rule 13)

SYNERGETIC FUNGICIDAL FORMULATIONs, PROCESS FOR PREPARING AND USE THEREOF

We, COROMANDEL INTERNATIONAL LIMITED,
an Indian company incorporated under Companies Act of 1956, having its principal place of business at Coromandel House, Sardar Patel Road, Secunderabad – 500 003, Telangana, India.

The following specification particularly describes the invention and the manner in which it is to be performed:

FIELD OF THE INVENTION
The present invention relates to synergistic fungicidal composition comprising combination of two fungicides.
The present invention also relates to synergistic fungicidal composition comprising combination of two fungicides, wherein said two fungicides are selected from any two of Tebuconazole, Cyproconazole and Pyraclostrobin.
The present invention specifically relates to synergistic fungicidal composition comprising combination of two fungicides, wetting agents, dispersing agents and agrochemical auxiliaries, wherein said two fungicides are selected from any two of Tebuconazole, Cyproconazole and Pyraclostrobin.
The present invention more specifically relates to synergistic fungicidal composition comprising combination of two fungicides at a weight in the ratio of 1 : 10 to 10 : 1 from first fungicide to second fungicide, a wetting agent, dispersing agent and other agrochemical auxiliaries, wherein said two fungicides are selected from any two of Tebuconazole, Cyproconazole and Pyraclostrobin.
The present invention also relates to a process for the preparation of synergistic fungicidal composition comprising combination of two fungicides, wherein said two fungicides are selected from any two of Tebuconazole, Cyproconazole and Pyraclostrobin.

BACKGROUND OF THE INVENTION
Tebuconazole is a triazole fungicide used agriculturally to treat plant pathogenic fungi. Tebuconazole is chemically known as (RS)-1-(4-chlorophenyl)- 4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol and has the following structure:

It has been found that the use of Tebuconazole is effective in combatting or preventing fungal diseases. Tebuconazole is effective in controlling fungal infestations by inhibiting one specific enzyme, C14-demethylase, which plays a role in sterol production. Sterols, such as ergosterol, are needed for membrane structure and function, making them essential for the development of functional cell walls by the fungi.
Cyproconazole is an agricultural fungicide of the class of azoles, used on cereal crops, coffee, sugar beet, fruit trees and grapes, on sod farms and golf courses and on wood as a preservative. Cyproconazole is used against powdery mildew, rust on cereals and apple scab, and applied by air or on the ground It controls the following pests: Puccinia graminis, Puccinia spp., Pseudocercosporella herpotrichoides and Septoria species. It can be used on above-ground wood to prevent it from decay from fungi as an alternative to chromated copper arsenate.
Cyproconazole is chemically known as 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)-2-butanol and is depicted by the structure given below :

Cyproconazole inhibits demethylation, a particular step in the synthesis of a component of the fungal cell wall called sterol. This means it affects fungal growth, but not the fungal sporulation. This explains why it must be used when fungal growth is maximum, early in the infection, because in late infections fungal growth slows down and the agent is ineffective.
Pyraclostrobin is chemically, methyl N-{2-[1-(4-chlorophenyl)pyrazol-3-yloxymethyl]phenyl}(N-methoxy)carbamate and has the following structure:

Many different formulations exist with imazalil, difenoconazole, prochloraz, propiconazole, chlorothalonil, cyprodinil, fludioxonil, azoxystrobin, and copper. In wood preservatives it is mixed with didecyldimethylammonium chloride. It is the active ingredient in two foliar fungicides for soybeans in the U.S., Alto X, and mixed with azoxystrobin in Quadris Xtra.
US 4,723,984 A disclose / claims Tebuconazole and compositions containing Tebuconazole.
US 4,664,696 A discloses / claims Cyproconazole and compositions containing Cyproconazole.
US 4,783,475 A claims compositions of Cyproconazole which contain additionally a guanidine.
US 5,869,517 A discloses Pyraclostrobin product.
CA 2 479 053 C discloses liquid pesticidal emulsifiable concentrate (EC) or an emulsion in water (EW) composition comprising one or more fungicides selected from the group consisting of epoxiconazole, tebuconazole, cyproconazole, prochloraz, penconazole, difenoconazole, flusilazole, metconazole, triadimenol, hexaconazole, flutriadol, triflumizole, fenbuconazole, bromuconazole, fluquinconazole, azaconazole, triticonazole, triadimefon, imibenconazole, strobliurin analogues, maneb, mancozeb, ziram, thiram and mixtures thereof as active ingredient, and a lactate ester selected from the group consisting of 2-ethyl hexyl lactate, cyclohexyl lactate, 2-methylcyclohexyl lactate, heptyl lactate, octyl lactate and mixtures thereof, in an amount sufficient to act as a crystal growth inhibitor.
EP 1 441 587 B1 discloses concentrated pesticidal solution which comprises one or more water-insoluble pesticides and lignin dissolved in a water miscible, polar solvent. This patent also discloses pesticide is a fungicide selected from the group consisting of azoxystrobin, picoxystrobin, tebuconazole, cyproconazole, and picoxystrobin in admixture with cyproconazole.
US 2002/0040044 A1 disclose pesticidal composition in form of an aqueous suspension concentrate, comprising a triazole fungicide which is substantially insoluble in water (<1% at room temperature) and solid at 25° C., and comprising as surfactants (1) a tristyrylphenol-ethoxylate or its sulfate or phosphate, in combination with either (2a) a vinylpyrrolidon homopolymer, or (2b) a vinylpyrrolidon/styrene blockpolymer, or (2c) a hydrophilic ethylene oxide-propylene oxide blockpolymer, or with a mixture thereof. This application also discloses that the composition may comprise additional pesticides, which are not triazole fungicides, but which preferably also fungicides.
WO 2009/091450 A1 discloses formulation comprising: an effective amount of a biocide selected from azoles such as one or more of propiconazole, difenoconazole, cyproconazole, tebuconazole and an alkyl poly glycol liquid carrier.
Tebuconazole 37%+Pyraclostrobin 8% WP is reported in literature.
Though, conventionally each of these active ingredients are used individually, and combination product with other products is approved, however, the combination composition of the present invention is not found. In view of the advantageous properties of the synergestic properties, there is increased interest in the use of active ingredients in combination to give synergistic results.
The inventors of the present invention surprisingly found that a combination of two fungicides selected from any two of Tebuconazole, Cyproconazole and Pyraclostrobin characterized by different modes of action, exhibits a considerable synergistic effect, allowing a higher fungicidal activity to be obtained than that envisaged on the basis of the activities of individual Tebuconazole, Cyproconazole and Pyraclostrobin.

OBJECTIVE OF INVENTION
The main objective of the present invention is to provide synergistic fungicidal composition comprising combination of two fungicides.
Another objective of the present invention is to provide synergistic fungicidal composition comprising combination of two fungicides, wherein said two fungicides are selected from any two of Tebuconazole, Cyproconazole and Pyraclostrobin.
Another objective of the present invention is to provide synergistic fungicidal composition comprising combination of two fungicides, wetting agents, dispersing agents and agrochemical auxiliaries, wherein said two fungicides are selected from any two of Tebuconazole, Cyproconazole and Pyraclostrobin.
Yet another objective of the present invention is to provide synergistic fungicidal composition comprising combination of two fungicides at a weight in the ratio of 1 : 10 to 10 : 1 from first fungicide to second fungicide, a wetting agent, dispersing agent and other agrochemical auxiliaries, wherein said two fungicides are selected from any two of Tebuconazole, Cyproconazole and Pyraclostrobin.
Still yet another objective of the present invention is to provide a process for the preparation of synergistic fungicidal composition comprising combination of two fungicides, wherein said two fungicides are selected from any two of Tebuconazole, Cyproconazole and Pyraclostrobin.

SUMMARY OF INVENTION
Accordingly, the present invention provides a synergistic fungicidal composition comprising combination two fungicides.
In another embodiment, the present invention provides a synergistic fungicidal composition comprising combination of two fungicides, wherein said two fungicides are selected from any two of Tebuconazole, Cyproconazole and Pyraclostrobin.
In another embodiment, the present invention provides a fungicidal composition comprising combination of two fungicides, wetting agents, dispersing agents and agrochemical auxiliaries, wherein said two fungicides are selected from any two of Tebuconazole, Cyproconazole and Pyraclostrobin.
In another embodiment, the present invention provides a fungicidal composition comprising combination of two fungicides at a weight in the ratio of 1 : 10 to 10 : 1 from first fungicide to second fungicide, a wetting agent, dispersing agent and other agrochemical auxiliaries, wherein said two fungicides are selected from any two of Tebuconazole, Cyproconazole and Pyraclostrobin.
In another embodiment, the present invention provides a fungicidal composition comprising combination of two fungicides, wetting agent, dispersing agent and other agrochemical auxiliaries, wherein said other agrochemical auxiliaries are selected from one or more of anti-freezing agent, viscocity modifying agent, biocide, deformer, filler and adjuvants.
In another embodiment, the present invention provides a fungicidal composition comprising combination of two fungicides, wetting agent, dispersing agent and other agrochemical auxiliaries, wherein said fungicidal composition is aqueous suspension concentrates (SC) or water dispersible granule (WDG).
In another embodiment, the present invention provides a fungicidal composition comprising combination of Tebuconazole and Pyraclostrobin, wetting agent, dispersing agent and other agrochemical auxiliaries. .
In another embodiment, the present invention provides a fungicidal composition comprising combination of Tebuconazole and Cyproconazole, wetting agent, dispersing agent and other agrochemical auxiliaries.
In another embodiment, the present invention provides a fungicidal composition comprising combination of Cyproconazole and Pyraclostrobin, wetting agent, dispersing agent and other agrochemical auxiliaries.
In another embodiment, the present invention provides a fungicidal composition comprising:
1% to 60 % (w/w) of first fungicide,
1% to 60 % (w/w) of second fungicide,
1% to 15% (w/w) of wetting agent,
1% to 15% (w/w) of dispersing agent, and
0.1% to 70% (w/w) of other agrochemical auxiliaries.
In another embodiment, the present invention provides a fungicidal composition comprising:
1% to 60 % (w/w) of Tebuconazole,
1% to 60 % (w/w) of Pyraclostrobin,
1% to 15% (w/w) of wetting agent,
1% to 15% (w/w) of dispersing agent, and
0.1% to 70% (w/w) of other agrochemical auxiliaries.
In another embodiment, the present invention provides a fungicidal composition comprising:
1% to 60 % (w/w) of Cyproconazole,
1% to 60 % (w/w) of Pyraclostrobin,
1% to 15% (w/w) of wetting agent,
1% to 15% (w/w) of dispersing agent, and
0.1% to 70% (w/w) of other agrochemical auxiliaries.
In another embodiment, the present invention provides a fungicidal composition comprising:
1% to 60 % (w/w) of Tebuconazole,
1% to 60 % (w/w) of Cyproconazole,
1% to 15% (w/w) of wetting agent,
1% to 15% (w/w) of dispersing agent, and
0.1% to 70% (w/w) of other agrochemical auxiliaries.
In another embodiment, the present invention provides a fungicidal aqueous suspension concentrates composition comprising:
1% to 60 % (w/w) of Tebuconazole,
1% to 60 % (w/w) of Pyraclostrobin,
1% to 15% (w/w) of alkyl ethoxylates,
1% to 20% (w/w) of propylene Glycol
0.01% to 10% (w/w) of polydimethyl siloxane antifoam emulsion
0.1% to 1% (w/w) of 1,2-benzisothiazolin-3-one
0.1% to 20% (w/w) of xanthan gum, and
30% to 70% (w/w) of demineralized water.
In another embodiment, the present invention provides a fungicidal aqueous suspension concentrates composition comprising:
1% to 60 % (w/w) of Tebuconazole,
1% to 60% (w/w) of Cyproconazole,
1% to 15% (w/w) of polyoxyethylene alkyl ether (NPE-free),
1% to 15% (w/w) of polymethyl methacrylate-polyethylene glycol graft
copolymer,
1% to 20% (w/w) of propylene glycol,
0.1% to 20% (w/w) of xanthan gum,
0.01% to 10% (w/w) of polydimethyl siloxane antifoam emulsion,
0.1% to 1% (w/w) of 1,2-benzisothiazolin-3-one, and
30% to 70% of purified water.
In another embodiment, the present invention provides a fungicidal aqueous suspension concentrates composition comprising:
1% to 60 % (w/w) of Cyproconazole,
1% to 60% (w/w) of Pyraclostrobin,
1% to 15% (w/w) of wetting agent/dispersing agents selected from EO/PO polymeric dispersant, ethoxylated TSP-phosphate ester, polyoxyalkylene glycol butyl ether, polyethylene glycol 2,4,6-tris(1-phenylethyl)phenyl ether sulfate ammonium salt, amine salt of polyarylphenyl ether phosphate, polyoxyethylene-polyoxypropylene block polymer, polyoxyethylene alkyl ether and methyl methacrylate graft copolymer.
1% to 20% (w/w) of propylene glycol,
0.1% to 20% (w/w) of xanthan gum,
0.01% to 10% (w/w) of polydimethyl siloxane antifoam emulsion,
0.1% to 1% (w/w) of 1,2-benzisothiazolin-3-one, and
30% to 70% of purified water.
In another embodiment, the present invention provides a fungicidal water dispersible granule composition comprising:
1% to 60 % (w/w) of Cyproconazole,
1% to 60% (w/w) of Pyraclostrobin,
1% to 15% (w/w) of wetting agents selected from alkylnaphthalene sulfonate (ANS) condensate blend, dialkyl naphthalene sulphonate sodium salt, linear alcohol derivative and polyethyleneglycol nonylphenyl ether ammonium sulfate,
1% to 15% (w/w) of dispersing agents selected from phenol sulfonic acid-formaldehyde, acrylate copolymer, sodium salt of methyl naphthalene sulfonate, phenol sulfonic acid-formaldehyde-polycondensation as sodium salt, sodium polycarboxylate, sodium methyl oleoyl taurate, sodium lignosulphonates and sodium lauryl sulphate,
30% to 80% (w/w) of fillers selected from aluminium silicate, corn starch, lactose monohydrate and calcium carbonate, and
0.1% to 20% (w/w) of amino acids.
The present invention also provides a process for the preparation of synergistic fungicidal suspension concentrates composition comprising combination of Tebuconazole and second fungicide, wherein the suspension concentrates is prepared by wet-mill method.
In another embodiment, the present invention provides a process for the preparation of synergistic fungicidal suspension concentrates composition comprising the steps of:
a. mixing water, antifreezing agent, wetting agent in pre mixer and then adding dispersant, biocide, preservative and defoamer,
b. adding the triazole fungicide with stirring,
c. adding second fungicide by stirring to from homogenized aqueous slurry,
d. wet milling the obtained slurry by passing through Dyno-Mill at a temperature less than 30?C, and
e. gelling the obtained wet milled slurry by adding viscosity modifying agent and stirring the mixture for 2hr to from homogenized suspension concentrates.
In another embodiment, the present invention provides a process for the preparation of synergistic fungicidal suspension concentrates composition comprising the steps of:
a. mixing water, propylene glycol, polyoxyethylene alkyl ether (NPE-free) in pre mixer and then adding polymethyl methacrylate-polyethylene glycol graft copolymer, 1,2-benzisothiazolin-3-one and polydimethyl siloxane antifoam emulsion,
b. stirring the obtained mixture for 20 minutes, adding and stirring Cyproconazole followed by Tebuconazole to from homogenized aqueous slurry,
c. wet milling the obtained slurry by passing through Dyno-Mill at a temperature less than 30?C, and
d. gelling the obtained wet milled slurry by adding xanthan gum and stirring the mixture for 2hr to from homogenized suspension concentrates.
In another embodiment, the present invention provides a process for the preparation of synergistic fungicidal suspension concentrates composition comprising the steps of:
a. mixing water, propylene glycol, alkyl ethoxylates, 1,2-benzisothiazolin-3-one and polydimethyl siloxane antifoam emulsion,
b. stirring the obtained mixture for 20 minutes, adding and stirring Pyraclostrobin followed by Tebuconazole to from homogenized aqueous slurry,
c. wet milling the obtained slurry by passing through Dyno-Mill at a temperature less than 30?C, and
d. gelling the obtained wet milled slurry by adding xanthan gum, propylene glycol and stirring the mixture for 2hr to from homogenized suspension concentrates.
In another embodiment, the present invention provides a process for the preparation of synergistic fungicidal water dispersible granule composition comprising the steps of:
a. mixing active agents and all excipients in a homogenizer for 60 to 120 minutes at a temperature of 30 to 50 °C,
b. milling the above mixture to obtain the desired particle size (D90 ~ 20 micro), and
c. cooling and collecting the oil suspension obtained above.
In another embodiment, the present invention provides a process for the preparation of synergistic fungicidal water dispersible granule composition comprising the steps of:
a. mixing Pyraclostrobin, Cyproconazole, alkylnaphthalene sulfonate (ANS) condensate blend, phenol sulfonic acid-formaldehyde, aluminium silicate and amino acids in a homogenizer for 60 to 120 minutes at a temperature of 30 to 50 °C,
b. milling the above mixture to obtain the desired particle size (D90 ~ 20 micro), and
c. cooling and collecting the oil suspension obtained above.

DETAILED DESCRIPTION OF THE INVENTION
The term "comprising", which is synonymous with "including", "containing", or "characterized by" here is defined as being inclusive or open-ended, and does not exclude additional, unrecited elements or method steps, unless the context clearly requires otherwise.
Tebuconazole and Cyproconazole may be present in the composition or applied in any amounts relative to each other, to provide the enhanced or synergistic effect of the mixture. Tebuconazole and Cyproconazole may be present in the synergistic fungicidal composition in any suitable amount, and is generally present in an amount of from 1% to 60% by weight of the composition, preferably from 5% to 50% by weight of the composition, more preferably from 10% to 50% by weight of the composition. In particular, the weight ratio of Tebuconazole and Cyproconazole in the composition independently is preferably in the range of from about about 5:1 to about 1:5 or about 3:1 to about 1:3. However, variables of the ratios of each of the active ingredients can be used and the selection of the particular amount is dependent upon many factors including, for example, type of formulations, the crop, disease sought to be controlled and environmental conditions. The selection of the proper quantity of active agent to be applied, however, is within the expertise of one skilled in the art.
Pyraclostrobin and Tebuconazole may be present in the composition or applied in any amounts relative to each other, to provide the enhanced or synergistic effect of the mixture. Pyraclostrobin and Tebuconazole may be present in the synergistic fungicidal composition in any suitable amount, and is generally present in an amount of from 1% 60% by weight of the composition, preferably from 5% to 50% by weight of the composition, more preferably from 10% to 50% by weight of the composition. In particular, the weight ratio of Pyraclostrobin and Tebuconazole in the composition independently is preferably in the range of from about 5:1 to about 1:5, or about 3:1 to about 1:3. However, variables of the ratios of each of the active ingredients can be used and the selection of the particular amount is dependent upon many factors including, for example, type of formulations, the crop, disease sought to be controlled and environmental conditions. The selection of the proper quantity of active agent to be applied, however, is within the expertise of one skilled in the art.
Pyraclostrobin and Cyproconazole may be present in the composition or applied in any amounts relative to each other, to provide the enhanced or synergistic effect of the mixture. Pyraclostrobin and Cyproconazole may be present in the synergistic fungicidal composition in any suitable amount, and is generally present in an amount of from 1% to 60% by weight of the composition, preferably from 5% to 50% by weight of the composition, more preferably from 5% to 40% by weight of the composition. In particular, the weight ratio of Pyraclostrobin and Cyproconazole in the composition independently is preferably in the range of from about 5:1 to about 1:5, or about 3:1 to about 1:3. However, variables of the ratios of each of the active ingredients can be used and the selection of the particular amount is dependent upon many factors including, for example, type of formulations, the crop, disease sought to be controlled and environmental conditions. The selection of the proper quantity of active agent to be applied, however, is within the expertise of one skilled in the art.
Formulation includes water soluble concentrate (SL), an emulsifiable concentrate (EC), an emulsion (EW), a microemulsion (ME), a suspension concentrates (SC), an oil-based dispersions (OD), a flowable suspension (FS), a water-dispersible granule (WDG), water-soluble granule (SG), a water-dispersible powder (WP), a water soluble powder (SP), a granule (GR), an encapsulated granule (CG), a fine granule (FG), a macrogranule (GG), an aqueous suspoemulsion (SE), capsule suspension (CS) and a microgranule (MG). Preferably, the synergistic fungicidal composition can be formulated as suspension concentrates (SC), water-dispersible powder (WP) or water-dispersible granule (WDG). Most preferably, the synergistic fungicidal composition can be formulated as suspension concentrates (SC) or water-dispersible granule (WDG).
The wetting agent is a compound that facilitates rapid wetting of the powder when added to the water. The wetting agent employed in the formulation composition is selected from the group consisting of non-ionic surfactants, anionic surfactant and a mixture of anionic and non-ionic surfactant and polymeric surfactant.
The wetting agent as used herein is selected from and not limited to a blend of anionic and nonionic surfactants (Atlox 5406B), polyoxyethylene alkyl ether (Atlox-4894), Amine salt of polyarylphenyl ether phosphate (SOPROPHOR FL), Amine salt of polyarylphenyl ether phosphate (Unitop FL), polycondensation product of naphthalene sulfonic acid, which is alkyl Naphthalene sulphonate sodium salt, alkylnaphthalene sulfonate (ANS) condensate blend (Morwet EFW, Morwet 3028), dialkyl naphthalene sulphonate sodium salt (Supragil WP), polyalkyl Naphthalene sulphonate; Aqarius BP14332 Yellow IH, salts of alkylphenol condensates, salts of sulphonated lignins, salts of poly acid resin copolymers, salts of polyphenol formaldehyde resins, salts of polyarylether sulphates such as tristyrylphenolethoxylate sulphate salts, Ethoxylated TSP-phosphate ester (Agrilan 1015), alkoxylated alkylphenols and alcohols as well as block copolymers of ethyleneoxide and propylene oxide, linear alcohol derivative (Geropon L wet), polyethyleneglycol nonylphenyl ether ammonium sulfate (Dispersol PS).
The wetting agent is present in the composition in a range of about 1% to 15%, more preferably 2% to 10% of the total weight of the composition.
The wetting agent may also be used as a dispersing agent.
The compositions of the present invention contain additional dispersing agents selected from and not limited to sodium lignosulphonates; sodium lauryl sulphate, sodium naphthalene sulphonate formaldehyde condensates; tristyrylphenol ethoxylate phosphate esters; aliphatic alcohol ethoxylates; alky ethoxylates; EO-PO block copolymers; and graft copolymers, polycarboxylates, alkyl naphthalene sulfonates (such as Morwet IP, Morwet EFW, Morwet 3028,), sodium salt of methyl naphthalene sulfonate (Supragil MNS 90), phenol sulphonic acid condensates, alkyl sulfonates, alkenyl sylfonates, mixture of alkyl sulfonates and alkenyl sylfonates (Lissapol D), alkyl suflosuccinates (Geropon), phenol sulfonic acid-formaldehyde-polycondensation as sodium salt (Dispersol PSR19), polymethyl methacrylate-polyethylene glycol graft copolymer (Atlox 4913), acrylate copolymer (Agrilan 789), alkyl ethoxylates (Geronol SCR), Polyoxyalkylene Glycol Butyl Ether (Ethylane NS 500LQ), Polyethylene glycol 2,4,6-tris(1-phenylethyl)phenyl ether sul fate ammonium salt (Sophrophor 4d384), Polyoxyethylene-Polyoxypropylene block Polymer (Unitop 203),methyl oleyltaurates and poly vinyl alcohols. Preferred dispersing agents are polycarboxylates, sodium polycarboxylate (Geropon T 36), sodium methyl oleoyl taurate (Geropon T 770), alkyl naphthalene sulfonates, phenol sulphonic acid condensates, phenol sulfonic acid-formaldehyde (Tamol DN), lignosulphonates, methyl oleyltaurates and poly vinyl alcohols, STEPSPERSE DF-600 is a blend of nonionic surfactant and sodium lignosulfonate, BREAK-THRU® DA 646 is a non-ionic dispersant based on a specialty polyether, BREAK-THRU® DA 647, a modified polyether, is a non-ionic dispersant, BREAK-THRU® DA 655 is a polyether phosphate, BREAK-THRU® DA 675 is a non-ionic, aqueous based organically modified polymer, Atlox Metasperse™ 550S Modified styrene acrylic polymer. Dispersing agents disclosed in US 6,677,399; US 6,767,865; EP 1 16 470; US 9,526,241 can be used in the present invention. Once the granule has been diluted in water, ready for spraying (with the aid of the wetting agent), a dispersant is required to maintain the particles in suspension and prevent them from agglomerating. The dispersing agent is a compound which ensures that the particles remain suspended in water. The dispersing agent can be ionic or non-ionic or a mixture of such surface active agents or graft co-polymer dispersant.
The dispersing agent is present in the composition in a range of about 1 to 15%, more preferably 2 to 10% of the total weight of the composition.
The antifreezing agent as used herein is selected from ethylene glycol, propylene glycol, other glycols, glycerine or urea.
The antifreezing agent present in the composition in a range of about 1% to 20%, more preferably 1% to 15% of the total weight of the composition.
The viscosity modifying agent as used herein includes all substances which can normally be used for this purpose in agrochemical compositions. For example, xanthan gum, PVOH, cellulose and its derivatives, clay hydrated silicates, magnesium aluminum silicates or a mixture thereof. The fungicidal composition may further comprise one or more solid adherents. Such adherents are known in the art and available commercially. They include organic adhesives, including tackifiers, such as celluloses of substituted celluloses, natural and synthetic polymers in the form of powders, granules, or lattices, and inorganic adhesives such as gypsum, silica, or cement.
The viscosity modifying agent present in the composition in a range of about 0.1% to 20%, more preferably 2% to 15% of the total weight of the composition.
The defoamer as used herein is selected from and not limited to absorbed polydimethyl siloxane, stearates; silicones (Polydimethyl siloxane antifoam emulsion (Sag-1572), SILFOAM®, SILFAR®, PULPSIL® and WACKER® AK) and ethoxylates.
The defoamer present in the composition in a range of about 0.01 to 10%, more preferably 0.1% to 5% of the total weight of the composition.
The suspension concentrates of the present invention optionally contains a biocide of Nipacide® BIT 20 which is a formaldehyde-free, in-can biocide based on benzisothiazolinone (BIT). It is an FDA approved, glycol-based solution exhibiting low toxicity. Effective against a wide range of microorganisms including gram positive & gram negative bacteria, yeast and fungi. It can be used over a wide pH and temperature range.
The biocide present in the composition in a range of about 0.1% to 1%, more preferably 0.1% to 0.5% of the total weight of the composition.
The inert fillers as used in the present invention includes but are not limited to water, natural minerals such as calcite, talc, china clay series, and montmorillonite or attapulgite clays including various forms of Bentonite, Kaolin; aluminium silicate, lactose, starches, calcium carbonate, calcium sulphate, calcium phosphate, sodium tripoly phosphate (STPP), woodflours, activated carbon, sugars, diatomaceous earth, cereal flours, fine-grain inorganic solids, and the like. Clays and inorganic solids which may be used include calcium bentonite, perlite, mica, vermiculite, silicas, quartz powder, montmorillonite and mixtures thereof. Sugars which may be useful include dextrin and maltodextrin. Cereal flours include wheat flour, oat flour and barley flour and a mixture thereof.
The inert filler present in the composition in a range of about 30% to 80%, more preferably 40% to 75% of the total weight of the composition.
The adjuvants as used in the present invention are includes but are not limited to amino acids (Active 30.1X).
The adjuvants present in the composition in a range of about 0.1% to 10%, more preferably 1% to 5% of the total weight of the composition
The suspension concentrate of the present invention can be diluted with water or water solutions of agronomic compounds before use to produce a sprayable composition which is used in treating plants or increasing plant growth, dilution in water usually results in suspensions, emulsions, suspoemulsions or solutions of the agrochemical active ingredient at a concentration of at least 0.001 g/l.
The formulated composition may for example be applied in spray form, e.g., employing appropriate dilutions. The rates of application (use) of the composition of the present invention may vary, for example, according to type of use, soil type, season, climate, soil ecology, type of plants, but is such that Tebuconazole and Cyproconazole in the combination in an effective amount to provide the desired action. The application rate of the composition for a given set of conditions can readily be determined by trials. The composition of the present invention may contain or be mixed with other pesticides, such as fungicides, insecticides and nematicides, growth factor and fertilizers, to enhance the activity of the association of the invention or to widen its spectrum of activity.
A particular mode of administering the composition of the present invention is the administration to the aboveground parts of plants, in particular to the leaves thereof (leaf-application). The number of applications and the administered doses are chosen in accordance with the biological and climatic conditions of life of the causative agent. The antifungal compositions though, can also be applied to the soil and get into the plants through the root system (systemic activity), in case the locus of the plants is sprayed with a liquid composition or if the components are added to the soil in a solid formulation e.g. in the form of granulate (soil application).
When using the active compound combinations according to the invention, the application rate can be varied within a relatively wide range, depending on the kind of application. For the treatment of parts of plants, the active-compound combination application rates are generally between 0.1 and 10 000 g/ha, preferably between 100 and 2500 g/ha. For seed dressing, the active compound combination application rates are generally between 0.001 and 50 g per kilogram of seed, preferably between 0.01 and 20 g per kilogram of seed. For the treatment of the soil, the active-compound combination application rates are generally between 0.1 and 10000 g/ha preferably between 1 and 5000 g/ha.
A synergistic fungicidal composition c surprisingly and substantially enhances the fungicidal effectiveness of individual fungicides, and vice versa. "Plant" as used herein, refers to all plant and plant populations such as desired and undesired wild plants or crop plants. "Plant parts" as used herein, refers to all parts and organs of plants, such as shoot, leaves, needles, stalks, stems, fruit bodies, fruits, seeds, roots, tubers and rhizomes. Harvested materials, and vegetative and generative propagation materials, for example, cutting, tubers, meristem tissue, rhizomes, offsets, seeds, single and multiple plant cells and any other plant tissues, are also included. The synergistic fungicidal composition according to the present invention is suitable for plants of the crops: cereals (wheat, barley, rye, oats, corn, rice, sorghum, triticale and related crops); fruit, such as pomes, stone fruit and soft fruit, such as apples, pears, plums, peaches, almonds, cherries, and berries, for example grape, strawberries, raspberries and blackberries; leguminous plants (beans, lentils, peas, soybeans); oil plants (rape, mustard, sunflowers); cucurbitaceae (marrows, cucumbers, melons); citrus fruit, such as oranges, lemons, grapefruit and mandarins; and vegetables (spinach, lettuce, asparagus, cabbages, carrots, onions, tomatoes, potatoes, paprika, chili). Preferably, the composition of the present invention is applied on cereals, fibre plants, leguminous plants and vegetables. More preferably, the composition is applied on cereals and vegetables. Each composition of the present invention can be used in the agricultural sector and related fields of use for preventing and/or treating fungal infestations example, but not limited to: Cercospora spp., Colletotrichum spp., Dreschlera spp., Erysiphe spp., Exserohilum spp., Microsphaera spp., Phaeoisariopsis spp., Phakopsora spp., Phakospsora spp., Puccinia spp., Septoria spp., Cercospora kikuchii, Cercospora sp., Colletotrichum gossypii, Dreschlera triticirepentis, Erysiphe diffusa, Exserohilum turcicum, Microsphaera diffusa, Phaeoisariopsis griseola, Phakopsora pachyrhizi, Phakospsora pachyrizhizi, Puccinia recondite, Septoria glycines and Septoria tritici. The synergistic fungicidal composition according to this invention is effective in preventing and/or treating fungal infestations caused by, particularly Cercospora spp., Colletotrichum spp., Dreschlera spp., Erysiphe spp., Exserohilum spp., Microsphaera spp., Phaeoisariopsis spp., Phakopsora spp., Phakospsora spp., Puccinia spp., and Septoria spp, in plants and plant parts, particularly plants and their plant parts of cereals, fibre plants, leguminous plants and vegetables.
The following examples describes the nature of the invention which are given only for the purpose of illustrating the present invention in more detail and are not limitative and relate to solutions, which have been particularly effective on bench scale.
EXAMPLES
Example 1: Composition of aqueous suspension concentrate
S. No. Ingredients/Raw Materials Quantity (% w/w)
1. Cyproconazole Technical @ 96%(b)12.5% 13.02
2. Tebuconazole Technical @97.5 (b) 12.5% 12.82
3. polyoxyethylene alkyl ether (Atlox-4894) 2.0
4. polymethyl methacrylate-polyethylene glycol graft copolymer (Atlox-4913) 3.0
5. Propylene glycol 10
6. 1, 2-benzisothiazolin-3-one (Nipacide BIT-20) 0.1
7. Xanthan gum (2% of Agropol 23W gel-suspension) 5.0
8. polydimethyl siloxane antifoam emulsion (Sag-1572) 0.3
9. Water 53.76
Total 100

Manufacturing process:
Step -1: Preparation of Aqueous Slurry
100% water and 10 parts by weight of Propylene Glycol, 2.0 parts by weight of Atlox-4894 and parts by weight of each are taken in Vessel No 1 (pre mixer). To this 3.0 parts by weight of Atlox-4913, 0.1 parts by weight of Nipacide BIT-20 and 0.3 parts by weight of deformer are added. The mixture was stirred for 20 minutes and then Cyproconazole technical was added. The stirring was continued and subsequently Tebuconazole technical was added. The mixture was stirred for homogenization (the mixture should be thoroughly homogenized).

Step - 2: Wet Milling of Slurry
The wet slurry from Vessel No 1 was passed through Dyno-Mill at a temperature less than 30?C and material was collected in Vessel No.2 (Post-Mixer). Continuous stirring was maintained in both the vessels to avoid the sedimentation.
The Particle Size distribution (PSD) of the sample was checked. The PSD of the material should be in between d90 < 8 -10µ. If the d90 is higher than > 10µ then grind the mixture further till the PSD value complies the specification.
Step 3: Gelling of Wet Milled Slurry.
The required quantity of xanthum gum was added to the wet slurry in Vessel No 2 and the mixture was stirred for 2 h for homogenization. The sample was checked for complete analysis and packed in COEX Bottle.

Example 2: Composition of aqueous suspension concentrate
S. No. Ingredients/Raw Materials Quantity(% w/w)
1. Pyraclostrobin technical (a)97.45% (b)10% 10.26
2. Tebuconazole technical (a)97.5% (b) 12.5% 12.82
3. alkyl ethoxylates (Geronol SCR) 3.0
4. Propylene Glycol 10.0
5. polydimethyl siloxane antifoam emulsion (SAG 1572) 0.5
6. 1, 2-benzisothiazolin-3-one (Nipacide BIT-20) 0.2
7. Xanthan gum (2% of Agropol 23W gel-suspension) 10.0
8. Demineralized water QS
Total 100

Manufacturing process:
Step -1: Preparation of Aqueous Slurry
Water, Propylene Glycol, Geronol SCR, SAG 1572 and Nipacide BIT 20 are taken in Vessel No 1 (pre mixer). This mixture was stirred for 30 mins in homogenizer and to this Pyraclostrobin technical and followed by Tebuconazole technical.
Step - 2: Wet Milling of Slurry
The wet slurry was passed through Dyno-Mill at a temperature less than 30?C and maintaining continuous agitation in feeder of the Dyno-Mill.
The Particle Size distribution (PSD) of the sample was checked. The PSD of the material should be in between d90 < 5µ. If the d90 is higher than > 5µ then grind the mixture further till the PSD value complies the specification.
Step 3: Gelling of Wet Milled Slurry.
The required quantity of Agropol 23 W and 4 parts of Propylene glycol in 94 parts of distilled water and the mixture was stirred until it forms lumps-free smooth homogeneous gel-suspension. The formed gel was added to the milled slurry. The sample was checked for complete analysis and packed in a Bottle.
ompositions of examples 3-7 were also prepared using the similar method used for the preparation of example 2 composition.

Example 3: Composition of aqueous suspension concentrate
S.No. Ingredients/Raw Materials Quantity(% w/w)
1. Pyraclostrobin Technical @ 96%(b)7.5 % 7.8125
2. Cyproconazole Technical @ 96%(b)12.5% 13.02
3. EO/PO Polymeric dispersant (Geronol SCR) 5
4. Propylene glycol 10
5. 1,2-Benzisothiazol-3(2H)-one (Nipacide BIT-20) 0.1
6. Xanthan gum (AG-RHO POL 23/W ( 2%)) 10
7. Polydimethylsiloxane antifoam emulsion (Sag-1572) 0.5
8. Distilled water 53.56
Total 100

Example 4: Composition of aqueous suspension concentrate
S. No. Ingredients/Raw Materials Quantity(% w/w)
1. Pyraclostrobin Technical @ 96%(b)7.5 % 7.8125
2. Cyproconazole Technical @ 96%(b)12.5% 13.02
3. Ethoxylated TSP-phosphate ester (Agrilan 1015) 2
4. Polyoxyalkylene Glycol Butyl Ether (Ethylane NS 500LQ) 2
5. Propylene glycol 10
6. 1,2-Benzisothiazol-3(2H)-one (Nipacide BIT-20) 0.1
7. Xanthan gum (AG-RHO POL 23/W ( 2%)) 10
8. Polydimethylsiloxane antifoam emulsion (Sag-1572) 0.5
9. Distilled water 54.56
Total 100

Example 5: Composition of aqueous suspension concentrate
S. No. Ingredients/Raw Materials Quantity(% w/w)
1. Pyraclostrobin Technical @ 96%(b)7.5 % 7.8125
2. Cyproconazole Technical @ 96%(b)12.5% 13.02
3. Polyethylene glycol 2,4,6-tris(1-phenylethyl)phenyl ether sulfate ammonium salt (Sophrophor 4d384) 2
4. Amine salt of polyarylphenyl ether phosphate (SOPROPHOR FL) 2
5. Propylene glycol 10
6. 1,2-Benzisothiazol-3(2H)-one (Nipacide BIT-20) 0.1
7. Xanthan gum (AG-RHO POL 23/W ( 2%)) 10
8. Polydimethylsiloxane antifoam emulsion (Sag-1572) 0.5
9. Distilled water 54.56
Total 100

Example 6: Composition of aqueous suspension concentrate
S.No. Ingredients/Raw Materials Quantity(% w/w)
1. Pyraclostrobin Technical @ 96%(b)7.5 % 7.8125
2. Cyproconazole Technical @ 96%(b)12.5% 13.02
3. polyoxyethylene-polyoxypropylene block Polymer (Unitop 203) 1.5
4. Amine salt of polyarylphenyl ether phosphate (Unitop FL) 1.5
5. Propylene glycol 10
6. 1,2-Benzisothiazol-3(2H)-one (Nipacide BIT-20) 0.1
7. Xanthan gum (AG-RHO POL 23/W ( 2%)) 10
8. Polydimethylsiloxane antifoam emulsion (Sag-1572) 0.5
9. Distilled water 55.56
Total 100

Example 7: Composition of aqueous suspension concentrate
S. No. Ingredients/Raw Materials Quantity(% w/w)
1. Pyraclostrobin Technical @ 96%(b)7.5 % 7.8125
2. Cyproconazole Technical @ 96%(b)12.5% 13.02
3. polyoxyethylene alkyl ether (NPE-free) (Atlox 4894) 1.5
4. Methyl methacrylate graft copolymer (Atlox 4913) 1.5
5. Propylene glycol 10
6. 1,2-Benzisothiazol-3(2H)-one (Nipacide BIT-20) 0.1
7. Xanthan gum (AG-RHO POL 23/W ( 2%)) 10
8. Polydimethylsiloxane antifoam emulsion (Sag-1572) 0.5
9. Distilled water 55.56
Total 100

Example 8: Composition of water dispersible granules
S. No. Ingredients/Raw Materials Quantity(% w/w)
1. Pyraclostrobin @98 % (b) 7.5 % 7.63
2. Cyproconazole @97 (b) 12.5% 12.88
3. alkylnaphthalene sulfonate (ANS) condensate blend (Morwet EFW) 2.0
4. phenol sulfonic acid-formaldehyde (Tamol DN) 4.0
5. aluminium silicate (China clay) 70.46
6. amino acids (Active 30.1X) 3.0
Total 100%

Manufacturing process
All the raw materials were weighed, dispensed and the mixture was mixed in a homogenizer for 60 to 120 minutes at a temperature of 30 to 50 °C. The mixture was milled to obtain the desired particle size (D90 ~ 20 micro) and stirred for another 4 hours. The oil suspension was cooled and collected.

Compositions of examples 9-12 were also prepared using the similar method used for the preparation of example 8 composition.

Example 9: Composition of water dispersible granules
S. No. Ingredients/Raw Materials Quantity(% w/w)
1. Pyraclostrobin @98 % (b) 7.5 % 7.63
2. Cyproconazole @97 (b) 12.5% 12.88
3. alkylnaphthalene sulfonate (ANS) condensate blend (Morwet 3028) 2.0
4. acrylate copolymer (Agrilan 789) 5.0
5. corn starch 69.46
6. amino acids (Active 30.1X) 3.0
Total 100%

Example 10: Composition of water dispersible granules
S. No. Ingredients/Raw Materials Quantity(% w/w)
1. Pyraclostrobin @98 % (b) 7.5 % 7.63
2. Cyproconazole @97 (b) 12.5% 12.88
3. dialkyl naphthalene sulphonate sodium salt (Supragil WP) 3.0
4. Sodium salt of methyl naphthalene sulfonate (Supragil MNS 90) 2.0
5. phenol sulfonic acid-formaldehyde-polycondensation as sodium salt (Dispersol PSR19) 2.0
6. lactose Monohydrate 69.46
7. amino acids (Active 30.1X) 3.0
Total 100%

Example 11: Composition of water dispersible granules
S. No. Ingredients/Raw Materials Quantity(% w/w)
1. Pyraclostrobin @98 % (b) 7.5 % 7.63
2. Cyproconazole @97 (b) 12.5% 12.88
3. linear alcohol derivative (Geropon L wet) 2.0
4. sodium polycarboxylate (Geropon T 36) 2.0
5. sodium methyl oleoyl taurate (Geropon T 77) 2.0
6. calcium carbonate 70.46
7. amino acids (Active 30.1X) 3.0
Total 100%

Example 12: Composition of water dispersible granules
S. No. Ingredients/Raw Materials Quantity(% w/w)
1. Pyraclostrobin @98 % (b) 7.5 % 7.63
2. Cyproconazole @97 (b) 12.5% 12.88
3. polyethyleneglycol nonylphenyl ether ammonium sulfate (Dispersol PS) 4.0
4. sodium lignosulphonate 2.0
5. sodium lauryl sulphate 2.0
6. Aluminium silicate (Bentonite clay) 68.46
7. amino acids (Active 30.1X) 3.0
Total 100%

Field Bio-efficacy trials for Example 1:

Trial 1: Bio-efficacy against rice sheath blight
The sheath blight is caused by the fungal pathogen Rhizoctonia solani. This is potentially devasting disease can infect rice foliage at any stage of crop development. Its major threat to many crops and can also affect the crop stand and yield. Rhizoctonia solani fungus is cosmopolitan, polyphagous, widely distributed in tropical, subtropical, and temperate regions and for its development required hot and humid environment. The fungus spreads in the field by growing its runner hyphae from tiller to tiller, from leaf to leaf, and from plant to plant, resulting in a circular pattern of damage. The infection spreads most quickly when susceptible varieties are grown under favourable conditions such as warm temperature (28 to 32°C), high humidity (95% or above), and dense stands with a heavily developed canopy.

Field trials were conducted and the efficacy of suspension concentrates of Tebuconazole and Cyproconazole of the present invention (Example 1) was evaluated against Rhizoctonia solani fungus in rice crop. Trial was conducted with randomized block design with net plot size of 5m x 6m. Rice crop was raised with all standard agronomic practices. Spraying was done with manual operated backpack knapsack sprayer with 500 L of water spray volume per hectare at 45 days after transplanting.

The visual observations were recorded for % disease control from ten hills per plot. The observations were recorded at before spraying, 7 DAA (Days after application) and 14 DAA (Days after application). The percentage insect control and percentage disease control, the synergism was calculated and it was observed that the percentage of pesticidal control for the combination is greater than the expected percentage, there is a synergistic effect.

Table 1: Sheath blight disease control in rice
Compositions Dose (gram active per hectare) Percentage disease control–Sheath blight.
07 DAA 14 DAA
Tebuconazole + Cyproconazole 25 % SC
(Example No.1) 200 90 85
Tebuconazole 12.5% EC 100 50 45
Cyproconazole 12.5% SL 100 60 50
WP - Wettable Powder, SC – Suspension concentrates, EC – Emulsion concentrates, OS – Oily suspension, SL – Solubilized liquid and DAA - Days after application.

The trial results show excellent efficacy of Tebuconazole 12.5% + Cyproconazole 12.5% SC combinations against sheath blight disease of rice. The solo application of two active ingredients tested, were also not able to provide satisfactory control of sheath blight disease. The combination of Tebuconazole 12.5% + Cyproconazole 12.5% SC found very promising against rice sheath blight in terms of efficacy as well as residual control.

Table 2: Percentage sheath blight disease control at 14 DAA
Compositions Dose
(g or ml/ha) % sheath blight disease control

Cyproconazole 100 50
Tebuconazole 100 45
Tebuconazole 12.5% + Cyproconazole 12.5% SC (Example No. 1) 200 85

The results in table 2 clearly demonstrate synergy between Cyproconazole and Tebuconazole in controlling rice sheath blight disease.

Field Bio-efficacy and Synergy studies (Example 2)
The sheath blight is caused by the fungal pathogen Rhizoctonia solani. This is potentially devasting disease can infect rice foliage at any stage of crop development. Its major threat to many crops and can also affect the crop stand and yield. Rhizoctonia solani fungus is cosmopolitan, polyphagous, widely distributed in tropical, subtropical, and temperate regions and for its development required hot and humid environment. The fungus spreads in the field by growing its runner hyphae from tiller to tiller, from leaf to leaf, and from plant to plant, resulting in a circular pattern of damage. The infection spreads most quickly when susceptible varieties are grown under favourable conditions such as warm temperature (28 to 32°C), high humidity (95% or above), and dense stands with a heavily developed canopy.

The field trial was conducted to evaluate the efficacy of innovative mixtures of Pyraclostrobin and Tebuconazole against Rhizoctonia solani fungus in rice crop. Trial was conducted with randomized block design with net plot size of 5m x 6m. rice crop was raised with all standard agronomic practices. Spraying was done with manual operated backpack knapsack sprayer with 500 L of water spray volume per hectare at 45 days after transplanting.

The visual observations were recorded for % disease control from ten hills per plot. The observations were recorded at before spraying, 7 DAA (Days after application) and 14 DAA (Days after application).

Table 1: sheath blight disease control in rice
Compositions Dose (gram active per hectare) % Sheath blight disease control
7 DAA 14 DAA
Pyraclostrobin + Tebuconazole 20% SC (Example 2) 200 95 85
Pyraclostrobin 7.5% CS 75 55 40
Tebuconazole 12.5% EC 125 65 50
SC – Suspension concentrates, EC – Emulsion concentrates, CS – Capsule suspension, and DAA - Days after application.

The trial results show excellent efficacy of Pyraclostrobin 7.5% + Tebuconazole 12.5% SC combinations against sheath blight disease of rice. The solo application of two active ingredients tested here, were also not able to provide satisfactory control of sheath blight disease. The combination of Pyraclostrobin 7.5% + Tebuconazole 12.5% SC found very promising against rice sheath blight in terms of efficacy as well as residual control.

Table 2: Percentage sheath blight disease control at 14 DAA
Compositions Dose (gram active per hectare) % Sheath blight disease control
Pyraclostrobin 7.5% CS 75 40
Tebuconazole 12.5% EC 125 50
Pyraclostrobin + Tebuconazole 20% SC (Example 2) 200 85

The results in table 2 clearly demonstrate synergy between Pyraclostrobin and Tebuconazole in controlling rice sheath blight disease.

,CLAIMS:
WE CLAIM:
1. The fungicidal composition comprising:
1% to 60 % (w/w) of first fungicide,
1% to 60 % (w/w) of second fungicide,
1% to 15% (w/w) of wetting agent,
1% to 15% (w/w) of dispersing agent, and
0.1%to 70% (w/w) of other agrochemical auxiliaries.

2. The fungicidal composition as claimed in claim 1, wherein said fungicidal composition is aqueous suspension concentrate (SC) or water dispersible granule (WDG).

3. The fungicidal composition as claimed in claim 1, wherein said fungicidal composition comprising:
1% to 60 % (w/w) of Tebuconazole,
1% to 60 % (w/w) of Pyraclostrobin,
1% to 15% (w/w) of wetting agent,
1% to 15% (w/w) of dispersing agent, and
0.1% to 70% (w/w) of other agrochemical auxiliaries.

4. The fungicidal composition as claimed in claim 1, wherein said fungicidal composition comprising:
1% to 60 % (w/w) of Cyproconazole,
1% to 60 % (w/w) of Pyraclostrobin,
1% to 15% (w/w) of wetting agent,
1% to 15% (w/w) of dispersing agent, and
0.1% to 70% (w/w) of other agrochemical auxiliaries.

5. The fungicidal composition as claimed in claim 1, wherein said fungicidal composition comprising:
1% to 60 % (w/w) of Tebuconazole,
1% to 60 % (w/w) of Cyproconazole,
1% to 15% (w/w) of wetting agent,
1% to 15% (w/w) of dispersing agent, and
0.1% to 70% (w/w) of other agrochemical auxiliaries.

6. The fungicidal composition as claimed in claims 2 and 3, said fungicidal aqueous suspension concentrates composition comprising:
1% to 60 % (w/w) of Tebuconazole,
1% to 60 % (w/w) of Pyraclostrobin,
1% to 15% (w/w) of alkyl ethoxylates,
1% to 20% (w/w) of propylene Glycol
0.01% to 10% (w/w) of polydimethyl siloxane antifoam emulsion
0.1% to 1% (w/w) of 1,2-benzisothiazolin-3-one
0.1% to 20% (w/w) of xanthan gum, and
30% to 70% (w/w) of demineralized water.

7. The fungicidal composition as claimed in claims 2 and 4, said fungicidal aqueous suspension concentrates composition comprising:
1% to 60 % (w/w) of Cyproconazole,
1% to 60% (w/w) of Pyraclostrobin,
1% to 15% (w/w) of wetting agent/dispersing agents selected from EO/PO Polymeric dispersant, ethoxylated TSP-phosphate ester, polyoxyalkylene glycol butyl ether, Polyethylene glycol 2,4,6-tris(1-phenylethyl)phenyl ether sulfate ammonium salt, amine salt of polyarylphenyl ether phosphate, polyoxyethylene-polyoxypropylene block Polymer, polyoxyethylene alkyl ether and methyl methacrylate graft copolymer.
1% to 20% (w/w) of propylene glycol,
0.1% to 20% (w/w) of xanthan gum,
0.01% to 10% (w/w) of polydimethyl siloxane antifoam emulsion,
0.1% to 1% (w/w) of 1,2-benzisothiazolin-3-one, and
30% to 70% of purified water.

8. The fungicidal composition as claimed in claims 2 and 5, said fungicidal aqueous suspension concentrates composition comprising:
1% to 60 % (w/w) of Tebuconazole,
1% to 60% (w/w) of Cyproconazole,
1% to 15% (w/w) of polyoxyethylene alkyl ether (NPE-free),
1% to 15% (w/w) of polymethyl methacrylate-polyethylene glycol graft copolymer,
1% to 20% (w/w) of propylene glycol,
0.1% to 20% (w/w) of xanthan gum,
0.01% to 10% (w/w) of polydimethyl siloxane antifoam emulsion,
0.1% to 1% (w/w) of 1,2-benzisothiazolin-3-one, and
30% to 70% of purified water.

9. A process for the preparation of synergistic fungicidal suspension concentrates composition as claimed in claim 2 wherein the process comprising the steps of:
a. mixing water, antifreezing agent, wetting agent in pre mixer and then adding dispersant, biocide, preservative and defoamer,
b. adding the triazole fungicide with stirring,
c. adding second fungicide by stirring to from homogenized aqueous slurry,
d. wet milling the obtained slurry by passing through Dyno-Mill at a temperature less than 30?C, and
e. gelling the obtained wet milled slurry by adding viscosity modifying agent and stirring the mixture for 2hr to from homogenized suspension concentrates.

10. A process for the preparation of synergistic fungicidal WDG composition as claimed in claim 2 wherein the process comprising the steps of:
a. mixing active agents and all excipients in a homogenizer for 60 to 120 minutes at a temperature of 30 to 50 °C,
b. milling the above mixture to obtain the desired particle size (D90 ~ 20 micro), and
c. cooling and collecting the oil suspension obtained above.

Dated this Twenty second (22nd) day of July, 2021

__________________________________
Dr. S. Padmaja
Agent for the Applicant
IN/PA/883