DESC:FORM 2

THE PATENTS ACT, 1970
(SECTION 39 OF 1970)
&
The Patents Rules, 2003

COMPLETE SPECIFICATION
(Section 10 and Rule 13)

SYNERGESTIC FUNGICIDAL COMBINATIONS, COMPOSITIONS, PROCESS FOR PREPARING AND USE THEREOF

We, COROMANDEL INTERNATIONAL LIMITED,
an Indian company incorporated under Companies Act of 1956, having its principal place of business at Coromandel House, Sardar Patel Road, Secunderabad – 500 003, Telangana, India.

The following specification particularly describes the invention and the manner in which it is to be performed:
FIELD OF THE INVENTION
The present invention relates to synergistic fungicidal water soluble powder (WS) composition comprising polymeric dithiocarbamate fungicide complex with zinc salt and triazole fungicide.

The present invention also relates to synergistic fungicidal water soluble powder composition comprising combination of Mancozeb and Tebuconazole.

The present invention specifically relates to synergistic fungicidal water soluble powder composition comprising combination of Mancozeb and Tebuconazole and other agrochemical auxiliaries.

The present invention more specifically relates to synergistic fungicidal water soluble powder composition comprising combination of Mancozeb and Tebuconazole, wetting agent, dispersing agent and other agrochemical auxiliaries.

The present invention more specifically relates to synergistic fungicidal water soluble powder composition comprising combination of Mancozeb and Tebuconazole at a weight ratio of 60 : 1 to 30 : 1, wetting agent, dispersing agent and other agrochemical auxiliaries.

The present invention also relates to a process for the preparation of synergistic fungicidal water soluble powder composition comprising combination of Mancozeb and Tebuconazole, wherein said water soluble powder is prepared by simple blending and milling.

BACKGROUND OF THE INVENTION
Fungicides are biocidal chemical compounds or biological organisms used to kill parasitic fungi or their spores. Fungi can cause serious damage in agriculture, resulting in critical losses of yield, quality, and profit. Fungicides are used both in agriculture and to fight fungal infections in animals. It is clear that, although pesticides remain indispensable in agriculture, a great potential still exists to improve their efficiency and thus reduce their input into the environmental and food chain. Depending on the field of application, the mode of application, and depending on physical, chemical and biological parameters, the active substances are employed as active substance formulation in the form of a mixture with customary carriers, adjuvants and additives.

Mancozeb is a dithiocarbamate salt fungicides, non-systemic agricultural fungicide with multi-site, protective action on contact which mainly inhibit binding of bacteria in vivo oxidation of pyruvate and pyruvate oxidation processes involved in lipoic dehydrogenase II mercapto group (SH). Widely used in the beet, cabbage, celery, peppers, beans, tomatoes, eggplant, potatoes, melons, such as watermelons, cotton, peanuts, wheat, corn, rice, hops, tea, rubber, citrus, grapes, mango, banana, lychee, pear, persimmon, peach, rose, tobacco.

Mancozeb is chemically, manganese ethylene is (dithiocarbamate) (polymeric) complex with zinc salt which is listed under FRAC code M:03 The "M" refers to Chemicals with Multi-Site Activity. "M" FRAC groups are defined as generally considered as a low risk group without any signs of resistance developing to the fungicides. The molecular formula is (C4H6MnN2S4)x(Zn)y and the structural formula is:

Mancozeb is a polymeric complex of the monomer illustrated which contains 20% manganese and 2.5% zinc

Tebuconazole is a triazole fungicide used agriculturally to treat plant pathogenic fungi. Tebuconazole is chemically known as (RS)-1-(4-chlorophenyl)- 4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol and has the following structure:


It has been found that the use of Tebuconazole is effective in combatting or preventing fungal diseases. Tebuconazole is effective in controlling fungal infestations by inhibiting one specific enzyme, C14-demethylase, which plays a role in sterol production. Sterols, such as ergosterol, are needed for membrane structure and function, making them essential for the development of functional cell walls by the fungi.

CN 1223274 C discloses wettable powder which is used for preventing and treating apple ring rot and alternaria leaf spot and is prepared by compounding Mancozeb and Tebuconazole. This patent also discloses that the weight ratio of the Mancozeb to tebuconazole is 1 to 50:1.

CN 101828566 A discloses pesticide composition composed of a systemic fungicide Tebuconazole, a protective fungicide Mancozeb, a wet spreading agent, and other auxiliary agents, etc., which can improve the germination of dormant sporangia of corn brown spot disease bacteria. This application also discloses composition of Tebuconazole and Mancozeb has a significant synergistic effect on the inhibition of the germination of the resting sporangia of the brown spot pathogen in the ratio of 4:1 to 1:4.

CN 105766957 A discloses bactericidal composition containing a triazole bactericide and Mancozeb, characterized in that the active ingredients in the bactericidal composition are a triazole bactericide and Mancozeb, and the triazole bactericide is selected from at least one of Tetraflurane, Tebuconazole, Cyclopropanazole, Enolazole, Fenazole, Hexanazole and Imidazole, the triazole bactericide and manganese, the weight ratio of zinc is 50:1-1:100. Described bactericidal composition is possibly together with dispersant, stabilizer, solvent, emulsifying agent, thickening agent, institute State bactericidal composition and be prepared as dry powder doses.

US 3,379,610 A claims Mancozeb product.

US 4,723,984 A disclose Tebuconazole or an acid addition salt or metal salt complex thereof and compositions containing Tebuconazole.

Though, conventionally each of these active ingredients are used individually, and combination product with other products is approved, however, the combination water soluble powder composition of the present invention is not found. In view of the advantageous properties of the synergestic properties, there is increased interest in the use of active ingredients in combination to give synergistic results.

We surprisingly found that a combination of Mancozeb and Tebuconazole combination water soluble powder composition of the present invention exhibits a considerable synergistic effect, allowing a higher fungicidal activity to be obtained than that envisaged on the basis of the activities of individual Mancozeb and Tebuconazole.

OBJECTIVE OF INVENTION
The main objective of the present invention is to provide synergistic fungicidal water soluble powder composition comprising polymeric dithiocarbamate fungicide complex with zinc salt and triazole fungicide.

Another objective of the present invention is to provide synergistic fungicidal water soluble powder composition comprising combination of Mancozeb and Tebuconazole.

Another objective of the present invention is to provide synergistic fungicidal water soluble powder composition comprising combination of Mancozeb and Tebuconazole and other agrochemical auxiliaries.

Another objective of the present invention is to provide synergistic fungicidal water soluble powder composition comprising combination of Mancozeb and Tebuconazole, a wetting agent, dispersing agent and other agrochemical auxiliaries.

Yet another objective of the present invention is to provide synergistic fungicidal water soluble powder composition comprising combination of Mancozeb and Tebuconazole, at a weight in the ratio of 60 : 1 to 30 : 1, a wetting agent, dispersing agent and other agrochemical auxiliaries.

Still yet another objective of the present invention is to provide a process for the preparation of synergistic fungicidal water soluble powder composition comprising combination of Mancozeb and Tebuconazole, wherein said water soluble powder is prepared by simple blending and milling.

SUMMARY OF INVENTION
Accordingly, the present invention provides synergistic fungicidal water soluble powder composition comprising polymeric dithiocarbamate fungicide complex with zinc salt and triazole fungicide.

In one embodiment, the present invention provides synergistic fungicidal water soluble powder composition comprising combination of Mancozeb and Tebuconazole.

In another embodiment, the present invention specifically provides synergistic fungicidal water soluble powder composition comprising combination of Mancozeb and Tebuconazole and other agrochemical auxiliaries.

In another embodiment, the present invention provides synergistic fungicidal water soluble powder composition comprising combination of Mancozeb and Tebuconazole, a wetting agent, dispersing agent and other agrochemical auxiliaries.

In another embodiment, the present invention more specifically provides synergistic fungicidal water soluble powder composition comprising combination of Mancozeb and Tebuconazole, at a weight in the ratio of 60 : 1 to 30 : 1 of first active ingredient to the second active ingredient, a wetting agent, dispersing agent and other agrochemical auxiliaries.

In another embodiment, the present invention provides a fungicidal water soluble powder composition comprising:
1 to 60 % (w/w) of Mancozeb as first active ingredient,
1% to 10% (w/w) of Tebuconazole as second active ingredient,
1% to 15% (w/w) of wetting agent,
1% to 15% (w/w) of dispersing agent, and
0.1% to 70% (w/w) of other additives /auxiliaries.

In another embodiment, the present invention provides a fungicidal water soluble powder composition comprising:
1 to 60 % (w/w) of Mancozeb as first active ingredient,
1% to 10% (w/w) of Tebuconazole as second active ingredient,
1% to 15% (w/w) of dialkyl naphthalene sulphonate sodium salt,
1% to 15% (w/w) of sodium lignosulphonate, and
0.1% to 70% (w/w) of other additives /auxiliaries.

In another embodiment, the present invention provides a fungicidal water soluble powder composition comprising:
1 to 60 % (w/w) of Mancozeb as first active ingredient,
1% to 10% (w/w) of Tebuconazole as second active ingredient,
1% to 15% (w/w) of wetting agent,
1% to 15% (w/w) of dispersing agent,
0.5% to 60% (w/w) of inert fillers, and
0.5% to 10% (w/w) of pigment.

In another embodiment, the present invention provides a fungicidal water soluble powder composition comprising:
1 to 60 % (w/w) of Mancozeb as first active ingredient,
1% to 10% (w/w) of Tebuconazole as second active ingredient,
1% to 15% (w/w) of dialkyl naphthalene sulphonate sodium salt,
1% to 15% (w/w) of sodium lignosulphonate,
0.5 to 60% (w/w) of hydrous aluminosilicate, and
0.5% to 10% (w/w) of naphthol AS pigment.

The present invention also provides a process for the preparation of synergistic fungicidal water soluble powder composition comprising combination of Mancozeb and Tebuconazole, wherein said water soluble powder is prepared by simple blending and milling.

In another embodiment, the present invention provides a process for the preparation of fungicidal water soluble powder composition comprising the steps of:
a. weighing and dispensing all the raw materials,
b. mixing weighed materials in a ribbon blender for 20 minutes,
c. milling the obtained mixed materials by passing through air jet milling instrument with an inlet pressure of 4 kg/cm2 and grinding pressure of 6 kg/ cm2, and
d. collecting and packaging obtained milled material to get water soluble powder.

In another embodiment, the present invention provides a process for the preparation of fungicidal water soluble powder composition comprising the steps of:
a. weighing and dispensing Mancozeb, Tebuconazole, dialkyl naphthalene sulphonate sodium salt, sodium lignosulphonate, hydrous aluminosilicate and naphthol AS pigment,
b. mixing weighed materials in a ribbon blender for 20 minutes,
c. milling the obtained mixed materials by passing through air jet milling instrument with an inlet pressure of 4 kg/cm2 and grinding pressure of 6 kg/ cm2, and
d. collecting and packaging obtained milled material to get Mancozeb and Tebuconazole water soluble powder.

DETAILED DESCRIPTION OF THE INVENTION
The term "comprising", which is synonymous with "including", "containing", or "characterized by" here is defined as being inclusive or open-ended, and does not exclude additional, unrecited elements or method steps, unless the context clearly requires otherwise.

Mancozeb and Tebuconazole may be present in the composition or applied in any amounts relative to each other, to provide the enhanced or synergistic effect of the mixture. Mancozeb and Tebuconazole may be present in the synergistic fungicidal composition in any suitable amount, and is generally present in an amount of from 60% to 10% by weight of the composition, preferably from 60% to 15% by weight of the composition. However, variables of the ratios of each of the active ingredients can be used and the selection of the particular amount is dependent upon many factors including, for example, type of formulations, the crop, disease sought to be controlled and environmental conditions. The selection of the proper quantity of active agent to be applied, however, is within the expertise of one skilled in the art.

Preferably, the synergistic fungicidal composition can be formulated as water soluble powder (WS), water-dispersible powder (WP) or water-dispersible granule (WDG). Most preferably, the synergistic fungicidal composition can be formulated as water soluble powder (WS).

The wetting agent is a compound that facilitates rapid wetting of the powder when added to the water. The wetting agent employed in the formulation composition is selected from the group consisting of non-ionic surfactants, anionic surfactant and a mixture of anionic and non-ionic surfactant and polymeric surfactant.

The wetting agent as used herein is selected from and not limited to a blend of anionic and nonionic surfactants (Atlox 5406B), polyoxyethylene alkyl ether (Atlox-4894), polymethyl methacrylate-polyethylene glycol graft copolymer (Atlox 4913), alkyl naphthalene sulfonates (such as Morwet IP, Morwet EFW, Morwet 3028, Supragil WP etc), polycondensation product of naphthalene sulfonic acid, which is alkyl naphthalene sulphonate sodium salt, polyalkyl naphthalene sulphonate; Aqarius BP14332 Yellow IH, salts of alkylphenol condensates, salts of sulphonated lignins, salts of poly acid resin copolymers, salts of polyphenol formaldehyde resins, salts of polyarylether sulphates such as tristyrylphenolethoxylate sulphate salts, alkoxylated alkylphenols and alcohols as well as block copolymers of ethyleneoxide and propylene oxide. Preferred wetting agent used in the composition of the present invention is polycondensation product of naphthalene sulfonic acid (Supragil WP, Supragil MNS-90).

The wetting agents present in the composition of the present invention are in the range of 1% to 15%, more preferably 2 to 10% of the total weight of the composition.

The wetting agent may also be used as a dispersing agent.

The compositions of the present invention contain additional dispersing agents selected from and not limited to sodium lignosulphonates; sodium naphthalene sulphonate formaldehyde condensates; tristyrylphenol ethoxylate phosphate esters; aliphatic alcohol ethoxylates; alky ethoxylates; EO-PO block copolymers; and graft copolymers, polycarboxylates, alkyl naphthalene sulfonates (such as Morwet IP, Morwet EFW, Morwet 3028,), phenol sulphonic acid condensates, alkyl sulfonates, alkenyl sylfonates, mixture of alkyl sulfonates and alkenyl sylfonates (Lissapol D), alkyl suflosuccinates (Geropon), L-Wet, methyl oleyltaurates and poly vinyl alcohols. Preferred dispersing agents are polycarboxylates, alkyl naphthalene sulfonates, phenol sulphonic acid condensates, lignosulphonates, methyl oleyltaurates and poly vinyl alcohols, STEPSPERSE DF-600 is a blend of nonionic surfactant and sodium lignosulfonate, BREAK-THRU® DA 646 is a non-ionic dispersant based on a specialty polyether, BREAK-THRU® DA 647, a modified polyether, is a non-ionic dispersant, BREAK-THRU® DA 655 is a polyether phosphate, BREAK-THRU® DA 675 is a non-ionic, aqueous based organically modified polymer, Atlox Metasperse™ 550S Modified styrene acrylic polymer. Dispersing agents disclosed in US 6,677,399; US 6,767,865; EP 1 16 470; US 9,526,241 can be used in the present invention. Once the granule has been diluted in water, ready for spraying (with the aid of the wetting agent), a dispersant is required to maintain the particles in suspension and prevent them from agglomerating. The dispersing agent is a compound which ensures that the particles remain suspended in water. The dispersing agent can be ionic or non-ionic or a mixture of such surface active agents or graft co-polymer dispersant. Preferred dispersing agent used in the composition of the present invention is sodium lignosulphonate.

The dispersing agent is present in the composition in a range of about 1 to 15%, more preferably 2 to 10% of the total weight of the composition.

The inert fillers as used in the present invention includes but are not limited to water, natural minerals such as calcite, talc, china clay series, and montmorillonite or attapulgite clays including various forms of Bentonite, Kaolin; lactose, starches, calcium carbonate, calcium sulphate, calcium phosphate, sodium tripoly phosphate (STPP), wood flours, activated carbon, sugars, diatomaceous earth, cereal flours, fine-grain inorganic solids, and the like. Clays and inorganic solids which may be used include calcium bentonite, perlite, mica, vermiculite, silica, silicate salts, quartz powder, montmorillonite and mixtures thereof. Sugars which may be useful include dextrin and maltodextrin. Cereal flours include wheat flour, oat flour and barley flour and a mixture thereof. Preferred inert fillers are lactose anhydrous and hydrous aluminosilicate (china clay). Highly disperse silica or highly disperse absorptive polymers may also be used to improve physical properties. Preferred inert fillers used in the composition of the present invention are hydrous aluminosilicate and precipitated silicon dioxide.

The inert fillers present in the composition of the present invention are in the range of 0.5 to 60%, more preferably 10 to 50% of the total weight of the composition.

Pigment as used in the present invention includes but are not limited to Naphthol AS pigment (Permanent Red FGR 03 IN), titanium dioxide, colour black, zinc oxide and blue pigments. Preferred pigment used in the composition of the present invention is naphthol AS pigment.

The pigment present in the composition of the present invention is in the range of 0.5 to 10%, more preferably 0.5 to 5% of the total weight of the composition.

The composition of the present invention may also include other excipients like stabilizer, compatibility agent, antifoam, stickers etc.

The compositions of the present invention can be diluted with water or water solutions of agronomic compounds before use to produce a sprayable composition which is used in treating plants or increasing plant growth. Dilution in water usually results in suspensions, emulsions, suspoemulsions or solutions of the agrochemical active ingredient at a concentration of at least 0.001 g/l.

The formulated composition may for example be applied in spray form, e.g., employing appropriate dilutions. The rates of application (use) of the composition of the present invention may vary, for example, according to type of use, soil type, season, climate, soil ecology, type of plants, but is such that Mancozeb and Tebuconazole in the combination in an effective amount to provide the desired action. The application rate of the composition for a given set of conditions can readily be determined by trials. The composition of the present invention may contain or be mixed with other pesticides, such as fungicides, insecticides and nematicides, growth factor and fertilizers, to enhance the activity of the association of the invention or to widen its spectrum of activity.

As examples of the wide variety of culture plants in which the combinations of present invention can be used, there may be named for example cereals, e.g. wheat, barley, rye, oats, rice, sorghum and the like; beets, e.g. sugar beet and fodder beet; pome and stone fruit and berries, e.g. apples, pears, plums, peaches, almonds, cherries, strawberries, raspberries and blackberries; leguminous plants, e.g. beans, lentils, peas, soy beans; oleaginous plants, e.g. rape, mustard, poppy, olive, sunflower, coconut, castor-oil plant, cocoa, ground-nuts; cucurbitaceae, e.g. pumpkins, gherkins, melons, cucumbers, squashes; fibrous plants, e.g. cotton, flax, hemp, jute; citrus fruit, e.g. orange, lemon, grapefruit, mandarin; vegetables, e.g. spinach, lettuce, asparagus, brassicaceae such as cabbages and turnips, carrots, onions, tomatoes, potatoes, hot and sweet peppers; laurel-like plants, e.g. avocado, cinnamon, camphor tree; or plants such as maize, tobacco, nuts, coffee, sugar-cane, tea, vines, hops, bananas, rubber plants, as well as ornamental plants, e.g. flowers, shrubs, deciduous trees and evergreen trees such as conifers. This enumeration of culture plants is given with the purpose of illustrating the invention and not to delimiting it thereto.

A particular mode of administering the composition of the present invention is the administration to the aboveground parts of plants, in particular to the leaves thereof (leaf-application). The number of applications and the administered doses are chosen in accordance with the biological and climatic conditions of life of the causative agent. The antifungal compositions though, can also be applied to the soil and get into the plants through the root system (systemic activity), in case the locus of the plants is sprayed with a liquid composition or if the components are added to the soil in a solid formulation e.g. in the form of granulate (soil application).

When using the active compound combinations according to the invention, the application rate can be varied within a relatively wide range, depending on the kind of application. For the treatment of parts of plants, the active-compound combination application rates are generally between 0.1 and 10,000 g/ha, preferably between 100 and 2500 g/ha. For seed dressing, the active compound combination application rates are generally between 0.001 and 50 g per kilogram of seed, preferably between 0.01 and 20 g per kilogram of seed. For the treatment of the soil, the active-compound combination application rates are generally between 0.1 and 10,000 g/ha preferably between 1 and 5000 g/ha.

Although the invention has been described above with reference to the disclosed embodiments, those skilled in the art will readily appreciate that the specific embodiments detailed are only illustrative of the invention. It should be understood that various modifications can be made without departing from the spirit of the invention. Accordingly, the invention is limited only by the claims.

The following examples describes the nature of the invention which are given only for the purpose of illustrating the present invention in more detail and are not limitative and relate to solutions, which have been particularly effective on bench scale.

EXAMPLES
Example 1: Composition of WS of the present invention:
S.No. Ingredients/Raw Materials Quantity
(% w/w)
1. Mancozeb Technical (85%) 47.05
2. Tebuconazole Technical 1.0
3. Dialkyl naphthalene sulphonate
sodium salt (Supragil WP) 2.0
4. Sodium Lignosulphonate 4.0
5. Ppt Silica 2.0
6. Hydrous aluminosilicate (China Clay) 42.5
7. Naphthol AS pigment (Permanent Red FGR 03 IN) 1.5
Total 100

Manufacturing process:
All the raw materials were weighed, dispensed and the mixture were mixed in a ribbon blender for 20 minutes. The mixture was passed through air jet milling instrument, inlet pressure - 4kg/cm2 and grinding pressure - 6kg/ cm2 for milling the sample. The milled material was collected and packed.

Field Trials Data:

The water soluble powder combination composition of Mancozeb and Tebuconazole of the present invention were prepared and field efficacy trials were done in the fields of soil borne Fungi viz., Rhizoctonia, Fusarium, Sclerotium and Aspergillus control in groundnut. The percent insect control and % disease control, the synergism was calculated and it was observed that the percentage of pesticidal control with the WS composition of the present invention is greater than the solo compositions and synergistic effect is observed.

The field efficacy against soil borne fungi control in groundnut were observed and compared with solo composition. The combination of Mancozeb 40% and Tebuconazole 1% WS has shown excellent efficacy as well as residual control over the both Mancozeb 75 WP and Tebuconazole 2% DS solo compositions.

Trial 1:
The soil borne fungi viz., Rhizoctonia, Fusarium, Sclerotium and Aspergillus cause severe damage to fresh growing seedlings and serious threat to many field crops at early stage of development and can also affect the crop stand and yield. Collar rot disease of groundnut is one of the most serious, destructive diseases in and yield losses range from 13 to 52% and can be as high as 93.6% in some areas. For a soil-inhabiting pathogen, many environmental and soil factors are responsible for the development of disease. These soil and seed borne fungi are widely distributed in tropical, subtropical, and temperate regions and attack large number of plants.

The field trial was conducted to evaluate the efficacy of innovative mixtures of Mancozeb and Tebuconazole against soil borne fungi in groundnut crop. The trial was conducted with randomized block design with net plot size of 7m x 7m. Groundnut crop was raised with all standard agronomic practices. Seed treatment was done manually by preparing slurry. The PDI observation were recorded at 14 and 28 DAA on per plot basis. The percent insect control and percent disease control, the synergism was calculated and it was observed that the percentage of pesticidal control for the combination is greater than the expected percentage.

Table 1: Soil borne Fungi control in groundnut:
Compositions Dose (gram active per hectare) Percent disease control –
soil borne fungi
14 DAA 28 DAA
Mancozeb 40% + Tebuconazole 1% WS (Example No. 1) 800 + 20 90 87.5
Mancozeb 40% + Tebuconazole 1% WS 1000 +25 95 95
Mancozeb 75 WP 800 50 45
Tebuconazole 2% DS 20 60 70
Mancozeb 75 WP 1000 60 50
Tebuconazole 2% DS 25 70 75
WS- Water Dispersible powders for slurry seed treatment, WP - Wettable Powder, DS – Dispersible Powder for dry seed treatment and DAA - Days after application.

The trial results shown excellent efficacy of Mancozeb 40% + Tebuconazole 1% combinations against collar rot disease of groundnut. The solo application of two active ingredients tested here, were also not able to provide satisfactory control of collar rot disease control. The combination of Mancozeb 40% + Tebuconazole 1% found very promising against groundnut collar rot in terms of efficacy as well as residual control.

,CLAIMS:WE CLAIM:
1. A fungicidal water soluble powder composition comprising:
1 to 60 % (w/w) of Mancozeb as first active ingredient,
1% to 10% (w/w) of Tebuconazole as second active ingredient,
1% to 15% (w/w) of wetting agent,
1% to 15% (w/w) of dispersing agent, and
0.1% to 70% (w/w) of other additives /auxiliaries.

2. The fungicidal water soluble powder composition as claimed in claim 1, wherein said composition comprising:
1 to 60 % (w/w) of Mancozeb as first active ingredient,
1% to 10% (w/w) of Tebuconazole as second active ingredient,
1% to 15% (w/w) of dialkyl naphthalene sulphonate sodium salt,
1% to 15% (w/w) of sodium lignosulphonate, and
0.1% to 70% (w/w) of other additives /auxiliaries.

3. The fungicidal water soluble powder composition as claimed in claim 1, wherein said composition comprising:
1 to 60 % (w/w) of Mancozeb as first active ingredient,
1% to 10% (w/w) of Tebuconazole as second active ingredient,
1% to 15% (w/w) of wetting agent,
1% to 15% (w/w) of dispersing agent,
0.5% to 60% (w/w) of inert fillers, and
0.5% to 10% (w/w) of pigment.

4. The fungicidal water soluble powder composition as claimed in claim 3, wherein said wetting agent is selected from blend of anionic and nonionic surfactants, polyoxyethylene alkyl ether, polymethyl methacrylate-polyethylene glycol graft copolymer, alkyl naphthalene sulfonates, polycondensation products of naphthalene sulfonic acid, which is dialkyl naphthalene sulphonate sodium salt, polyalkyl naphthalene sulphonate, salts of alkylphenol condensates, salts of sulphonated lignins, salts of poly acid resin copolymers, salts of polyphenol formaldehyde resins, salts of polyarylether sulphates such as tristyrylphenolethoxylate sulphate salts, alkoxylated alkylphenols and alcohols as well as block copolymers of ethyleneoxide and propylene oxide or mixtures thereof.

5. The fungicidal water soluble powder composition as claimed in claim 3, wherein said dispersing agent is selected from sodium lignosulphonates, sodium lauryl sulphate, sodium naphthalene sulphonate formaldehyde condensates, tristyrylphenol ethoxylate phosphate esters, alkyl sulfonates, alkenyl sylfonates, mixture of alkyl sulfonates and alkenyl sylfonates, methyl oleyltaurates and poly vinyl alcohols or mixtures thereof.

6. The fungicidal water soluble powder composition as claimed in claim 3, wherein said inert filler is selected from natural minerals such as calcite, talc, china clay series like hydrous aluminosilicate, lactose anhydrous, lactose monohydrate, starches, sodium sulphate, sodium bicarbonate, calcium carbonate, calcium sulphate, calcium phosphate, precipitated silicon dioxide or mixtures thereof.

7. The fungicidal water soluble powder composition as claimed in claim 3, wherein said pigment is selected from naphthol AS pigment, titanium dioxide, colour black, zinc oxide and blue pigments.

8. A process for the preparation of fungicidal water soluble powder composition comprising the steps of:
a. weighing and dispensing all the raw materials,
b. mixing weighed materials in a ribbon blender for 20 minutes,
c. milling the obtained mixed materials by passing through air jet milling instrument with an inlet pressure of 4 kg/cm2 and grinding pressure of 6 kg/ cm2, and
d. collecting and packaging obtained milled material to get water soluble powder.

9. The process for the preparation of water soluble powder composition as claimed in claim 8, wherein said process comprising the steps of:
a. weighing and dispensing Mancozeb, Tebuconazole, dialkyl naphthalene sulphonate sodium salt, sodium lignosulphonate, hydrous aluminosilicate and naphthol AS pigment,
b. mixing weighed materials in a ribbon blender for 20 minutes,
c. milling the obtained mixed materials by passing through air jet milling instrument with an inlet pressure of 4 kg/cm2 and grinding pressure of 6 kg/ cm2, and
d. collecting and packaging obtained milled material to get Mancozeb and Tebuconazole water soluble powder.

Dated this Twenty Sixth (26th) day of July, 2021

__________________________________
Dr. S. Padmaja
Agent for the Applicant
IN/PA/883