The present invention discloses an improved process for the preparation of 7-[4-[4-[-(2,3-dichlorophenyl)-l-piperazinyl]butoxy]-,3,4-dihydro-2-(IH)quinolinone(Aripiprazole),of formula-IIl , comprising condensation of l-(2,3dichlorophenyl) piperazine of formula 1 with 7-(4-bromobutoxy) 3,4-dihydro-2 (1H) quinolinone ...
Disclosed herein is a process for the preparation of polymorphic form I of (S)-Clopidogrel bisulfate( Formula I) in one pot manner which comprises the reaction of (+)-Tartarate salt of methyl ester of 2-chloro phenyl glycine with benzene sulfonic acid salt of thiophene-2-ethanol, followed by cyclizing Methyl (S)-(+)...
An improved process for the preparation of zolpidem and tartarate salt thereof, wherein zolpidic acid is reacted with phosphorous oxy chloride in ethyl acetate in presence of catalytic amount of dimethylformamide followed by treatment with dimethylamine to obtain zolpidem free base and converting the zolpidem free b...
Disclosed herein is novel amorphous hydrated forms of raloxifene hydrochloride, chemically termed as [6-hydroxy-2-(4-hydroxyphenyl)-benzothiophene-3-yl]-[4-[2-(l-piperidyl)ethoxy]phenyl]-methanone hydrochloride and process for preparation thereof.
The present invention discloses a simple and industrially scalable process for preparation of amorphous and crystalline form I of Dabigatran Etexilate Mesylate in good yield and purity.