The present invention relates to a process for preparation of compound of formula (I) that includes the steps of a) hydrogenation of compound of formula (VI) using metal catalyst; b) N-protection of compound of formula (V) with phthalic anhydride to form compound of formula (IV); c) bromination of compound of formul...
PROCESS FOR PREPARATION OF (2S, 3AS ,7AS)-OCTAHYDRO-1H-INDOLE-2-CARBOXYLIC ACID
The present invention relates to a process for preparation of compound of formula (A). The process for stereo-specific synthesis of (2S,3aS,7aS)-Octahydro-1H-indole-2-carboxylic acid of formula (A) includes hydrogenation of compound o...
Provided herein is a process for preparation of Ruxolitinib of formula (I) and salts thereof. The process involves treating racemic mixture of R and S forms of formula (II) with a resolving agent, chiral di-anisoyl tartaric acid of formula (RA). The process comprises reacting racemic compound (II) with L-di-anisoyl ...
Provided is improved process for purification of deferasirox with reduced genotoxic impurity F less than 0.5 ppm. The process comprises the step of reacting crude deferasirox with a suitable ketone of formula (I) in a mixture of solvent and acid solution, and isolating deferasirox having impurity F less than 0.5 ppm...
Provided is process for the preparation of solid active pharmaceutical ingredient, such as montelukast sodium, using anti-solvent crystallization method.