An improved process for preparing a crystalline Form-I of 7-Cyclopentyl-N, N-dimethyl-2-((5-(piperazin-1-yl) pyridin-2-yl) amino)-7H-pyrrolo[2,3-d] pyrimidine-6-carboxamide that is cost effective and industrially viable.
ABSTRACT
An improved process for preparing a crystalline Form-A of succinic acid salt of 7-Cyclopentyl-N, N-dimethyl-2-((5-(piperazin-1-yl) pyridin-2-yl) amino)-7H-pyrrolo[2,3-d] pyrimidine-6- carboxamide. Ribociclib succinate Form-A obtained by the present invention has content of Impurity-D less than about 0.05% ...
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