The present invention provides an improved process for preparation of 1 -[[3-(6,7-dihydro-l-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4- ethoxyphenyI]sulphonyl]-4methypiperazine citrate (Sildenafil Citrate) of Polymorphic form I)

The invention encompasses an improved process for the synthesis of Linagliptin, denoted by Formula-1 by deprotecting a tert-butyloxy carbony] (Boc)-protected compound of-Formula-Ill in presence of organic acids such as formic acid, sulfonic acids such as 4-methylbenzenesulfonic acid (PTSA), methanesulfonic acid (MSA...

The present invention provides a process for preparation of (S)-N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide, compound of formula (1). Preferred embodiment of the process comprises; (b) Further purify the resulting compound using suitable purification method. (a) reacting (R)-N-5-(azid...

The present invention provides a process for preparation of (S)-N-({3-[3-fluoro-4-(morpholin-4-yl) phenyl]-2-oxo-l, 3-oxazolidin-5-yl} methyl) acetamide of formula I. The present invention further provides a process for the preparation of Form I of Linezolid of formula I.

The present application provides an improved process for the preparation of novel crystalline Celecoxib form Am of Formula (1) via condensation of 4,4,4-trifluoro-l-[4-(methyl)phenyl]-butane-l,3-dione of formula (2) with 4-sulphonamido phenylhydrazine hydrochloride of Formula (3) in water. The compound of Formul...

Abstract A Process for the preparation of Telmisartan of formula 1, and novel intermediates thereof, namely 4'-(bromomethyl)-N-hydroxybiphenyI-2-carboxamide compound of formula (3) and 4'-((l,4'-dimethyl-2'-propyl-2,6'-bi(lH-benzo[d]imidazol)-l'-yl)methyl)-N-hydroxybiphenyl-2-carboxamide compound of formula (5) ...

The present invention provides a process for manufacturing polymorph V of (1S-cis)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine hydrochloride (Sertraline hydrochloride polymorph V) of the formula: comprising the steps of suspending salt of (1S-cis)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-...

The present invention provides a process for preparation of 10,11-Dihydro-10-oxo-5H-dibenz[b, f]azepine-5-carboxamide, compound of formula (1). Preferred embodiment of the process comprises reacting compound of formula (2) with alkaline earth or alkali metal isocynate in presence of weak acid to yield compound o...

The present invention provides a process for preparation of (S)-N-({3-[3-fluoro-4-(morpholin-4-yI) phenyl]-2-oxo-l, 3-oxazolidin-5-yl} methyl) acetamide of formula I. The present invention further provides a novel process for the preparation of Form I of Linezolid of formula I.

The present invention provides an improved process for the preparation of Venlafaxine and the intermediates thereof. The present invention provides a process for preparing compound of formula IV an intermediate for preparing Venlafaxine by hydrogenating a compound of formula-III: (III) in the presence of toluene, wa...

The object of invention is providing the efficient process for preparation of Apixaban and its intermediate formula-Ill, name as ethyl l-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-l-yl)phenyl]-4,5,6,7-tetrahydro-lH-pyrazol-[3,4-c]pyridine-3-carbvoxylate by using ethyl 6-(4-iodophenyl)-l-(4-methoxyphenyl)-7-oxo-4)5...

The invention encompasses a Crystalline Form-A of Dihydralazine mesylate and process for its preparation. 1,4-dihydrazinyl-1,4-dihydrophthalazine methanesulfonate Formula I

The invention encompasses a one pot process for the preparation of Clotrimazole which comprises- a) Reacting o-chlorophenyi diphenyl chloromethane of Formula 2 with imidazole of Formula 3 in a solvent such as acetone or toluene and triethyl amine at reflux temperature; b) Optionally washing the organi...

Abstract The present invention relates to a process for the preparation of bis[2-(dimethylamino)ethyl] succinate an intermediate of succinyl choline chloride. It further relates to process for the preparation of succinyl choline chloride or pharmaceutically acceptable dehydrates thereof from the above intermediate....

The present invention relates to a novel process for the preparation of an eslicarbazepine intermediate (S)-acetyl mandelate of formula VII and further conversion of the above intermediate to eslicarbazepine of formula I.

.An improved process for preparation of 10 - 0x0 -10,1 l-dihydro-5H-dibenz[b,fj azepine -5 - carboxamide (oxcarbazepine) from 10-methoxy-5H-dibenz[b,f]azepine (10-methoxy iminostilbene) comprising the following steps,a) reacting 10-methoxyiminostilbene with sodium cyanate and monochrloro acetic acid us...

The present invention relates to an improved process for the preparation of key intermediate of Deferasirox "2-(2-hydroxyphenyl)-4H-benzo(e)[1,3]oxazin-4-one" by reacting Salicylic acid, thionyl chloride and Salicylamide in presence of a catalyst and solvent and further preparation of Deferasirox from the above inte...

The present invention describes an improved process for the preparation of Carbamazepine. The process involves reacting 5H-dibenzo[b,f]azepine-5-carbonyl chloride with an liquid ammonia in the presence of Methyl isobutyl ketone to obtain Carbamazepine.

The present invention relates to an improved process for the preparation of Apixaban and N-1 polymorph thereof.

The present invention relates to a process for the preparation of a key intermediate "(R)-2-[(2-(4-aminophenyl)ethyl)amino]-1-phenylethanol" or its hydrochloride of Mirabegron and process for the synthesis of Mirabegron therefrom.