The present disclosure is in relation to a compound of Formula I
Formula I
wherein ‘R’ is an acid, ‘n’ is an integer of 1-3, and its derivative, tautomeric form, stereoisomer, polymorph, solvate, polymorphs or intermediates thereof. The disclosure also relates to method of preparation of said compounds, and their...
The present disclosure relates to polymorphic form of PQQ and/or its salts represented by formula I
Formula I
wherein “n” and “m” are selected from a group consisting of: (a) “n” = 3, “m” = 0 and (b) “n” = 1, “m” = 2; and; R3 is Na+.
The present disclosure also relates to a process for preparing the polymor...
The present disclosure relates to compounds of Formula I and process of obtaining the same.
Said compounds of Formula I is employed in the syntheses of pyrroloquinoline quinone (PQQ),
4,5-dioxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid 2-allyl ester, 5-
ethoxy-5-hydroxy-4-oxo-4,5-dihydro-1H-...
The present disclosure relates generally to the field of Biotechnology and Protein Science, and specifically to Enzyme preparation. The present disclosure provides a process for preparation of recombinant and stable proteases including but not limited to Trypsin, Carboxypeptidase B and Kexin. The production of these...
“PROCESS FOR ENHANCED EXPRESSION OF INSULIN AND ITS ANALOGS AND METHODS THEREOF”
ABSTRACT
The present disclosure describes a method for production of recombinant peptides and proteins. In particular, the present disclosure relates to a method for the production of insulin and insulin analogs. The expression cons...
The present invention relates to primers and methods for analyzing chimerism in conditions such as Bone Marrow Transplantation (BMT) using a broad spectrum of Variable Number of Tandem Repeats (VNTRs) or Short Tandem Repeats (STRs) or a combination thereof by qPCR (Quantitative Real Time Polymerase Chain Reaction). ...
The present invention relates to a novel method for high throughput detection of wide range of genotoxins in eukaryotic cells wherein the eukaryotic cell based tool combines the ability to detect a broad spectrum of genotoxic signaling events and a simple and reproducible assay technique. The present invention furth...
The present invention relates to a recombinant DNA expression/secretion system in E. coliwherein the said system combines the potential of signal peptide-based translocation of recombinant proteins to the periplasmic space of E. coli with membrane defective mutants of E. coli to further aid secretion into the extrac...
Title: Synthesis of Tocotrienols from o-Cresol Derivatives
The present invention provides an environmentally benign, facile process forpreparation of Tocotrienols from commercially available derivatives of o-Cresol.
“A PROCESS FOR BIOGAS PRODUCTION AND APPLICATION THEREOF”
ABSTRACT
The present disclosure relates to a process for producing biogas by inoculating the waste cell with the dung of domestic animal and subjecting the inoculated wasted cell mass to anaerobic digestion. Said process produces enhanced biogas yield w...
Title:SYNTHESIS OF A GUANYLATE CYCLASE AGONIST BY FRAGMENTS BASED APPROACH.
The present invention provides a process for the synthesis of Plecanatide, a guanylate cyclase agonist. The process involves convergent synthesis with compounds, i.e.,fragment of peptides followed by cyclization. The method provides high ...
This invention relates to the field of synthetic organic chemistry. The invention provides an improved and economical method of preparation of Guanylate Cyclase 2c Agonist with high yield. The method of preparation has simple reaction operation, easy post-processing and economical value. The process can be easily sc...
The present invention relates to a process for preparation of compounds of Formula I and its isomers. Particularly, the present invention provides a process for the preparation of a type of Vitamin K2, Menaquinone 7 (MK-7). More particularly the disclosure involves process of preparing Menaquinone 7 (MK-7) and its i...
The present invention provides a continuous flow process for preparing sulphobutyl ether cyclodextrin derivative having an average degree of substitution of 5.8-6.9. The process can be scale up to >50 kg/day to meet the industrial requirements. The process comprises the steps of activation of cyclodextrin in presenc...
The present invention provides a method of preparation of GLP-1 peptides by using different peptide fragments having amino acid sequences SEQ ID NO:1 (Fragment IG), SEQ ID NO:2 (Fragment SG), Fragment BG, SEQ ID NO:3, and SEQ ID NO:4 and combinations thereof. The method of preparation is environmentally benign, simp...
The present invention relates to a method for the preparation of ß-D-galactosamine and its salts and a-D-galactosamine and its salts. The synthesis method reduces process steps, does not involve hazardous reactant conditions or use of expensive starting reagents, significantly reduces process cycle time, which in tu...
The present invention relates to a method for the preparation of cholesterol (Compound of Formula I). More specifically, the present invention relates to synthesizing intermediates involved in the synthesis of Compound of Formula I in a process efficient method. The present method does not involve expensive reagents...
The present invention relates to a process of preparation of glucagon-like peptide-1 (GLP-1) analogues using novel fragments approach with tagging approach. More particularly, the disclosure provides synthesis method of glucagon like peptides via fragment approach with tagging approach and sequential amino acids cou...
The present invention relates to the field of synthetic organic chemistry and provides a method for the preparation of glycolipid carboxylic acids and their salts. Specifically, the present invention involves the synthesis of compounds of Formula I and their salts through intermediates of Formula 1-d and Formula II....