A process for the preparation of Topiramate comprising hrdrogenation of azido sulphonate precursor compound in the presence of Raney nickel catalyst, and purification of Topiramate using solvents such as acetone and cyclohexane.
A process for the preparation of N-amino-3-azabicyclo[ 3.3.0]octane of Forumla (I) which comprises the steps of reacting dimesylate of cis-1,2-cyclopentanedimethanol with Hydrazine Hydrate in the temperature range of 60-80oC in the presence of a C1-C4 alcohol. Namino- substituted 3.3.0 azabicyclo octane is an interm...
A process for the preparation of pure Tranexamic acid from cyclohexane-1,4-dimethanol comprising reaction of cyclohexane-1,4-dimethanol with sodium bromide to obtain 4-bromomethyl cyclohexane-1-methanol which is further reacted with TEMPO to obtain 4-Bromomethyl cylohexane-1-carboxylic acid which on treatment with a...
A pharmaceutical agent, particularly a hypoglycemic agent for the treatment of blood sugar disorders, represented by the general formula:
or salts thereof, wherein:
R1 is an aryl ring preferably phenyl ring with at least one halogen atom wherein the halogen is selected from the list consisting of Fluorine, Chl...
A herbal formulation including the extracts of Pterocarpus, green coffee bean and Caralluma; their uses for controlling body weight and serum lipid levels; and the process for preparing the same. The herbal formulation may also contain extracts from additional herbs to enhance the activity of the formulation. The he...
A process for the preparation of pregabalin intermediate, 3-cyano-5-methylhexanoic acid alkyl ester, comprising condensation of Isobutyraldehyde and Methyl cyanoacetate followed by hydrogenation in the presence of palladium on carbon catalyst to yield 4-methyl-2-cyanopentanoic acid methyl ester which is further reac...
A process for the preparation of Aripiprazole of Formula (I) comprising the
steps of a) reacting 3-(2-nitro-4-hydroxyphenyl)propanonic acid with a Cl-
C6 alcohol in the presence of a catalyst suitable for esterification to
produce methyl[3-(4-Hydroxy-2-nitrophenyl)]propanoate; b) mono-O-
alkylating phenolic hydr...