A method for producing an ?? fluoroaldehyde compound according to the present invention comprises a step of reacting an ?? fluoroester compound with hydrogen (H2) in the presence of a base and a catalyst. When the method according to the present invention is employed it becomes possible to allow a hydrogenation reac...

A method for producing a pyrazole compound represented by general formula (5) of the invention comprises reacting a 2-acyl-3-aminoacrylic acid ester represented by general formula (1) and a hydrazine represented by general formula (4) in the presence of a base. (In the formula (1), R1, R2, R3 and R4 are each indepen...

2Provided is a practical method for manufacturing 3 3 difluoro 2 hydroxypropionic acid which is important as an intermediate for medical and agricultural chemicals. By reacting a 4 4 difluoro 3 oxobutanoic acid ester with chlorine (Cl) a 4 4 difluoro 2 2 dichloro 3 oxobutanoic acid ester is obtained. By then reactin...

The present invention is a process for producing an α-fluoroaldehydes characterized by reacting α-fluoroester with hydrogen gas (H2) in the presence of a ruthenium catalyst. The present invention makes the production of α-fluoroaldehydes on an industrial scale relatively easy, and enables not only the hydrate (the p...

Disclosed is a solvent composition for silicone compounds, containing 1-chloro-3,3,3-trifluoropropene, or a solvent composition for silicone compounds, containing (A) 1-chloro-3,3,3-trifluoropropene and (B) a compound made up of at least one selected from the group consisting of 1,1,2,2-tetrafluoro-1-methoxyetha...

To provide a sensitive antenna with simple pattern, there is provided an antenna including a core-side element (1) connected to a core-side feed point (3) and a ground-side element (2) connected to a ground-side feed point (4), characterized in that: the core-side element extends from the core-side feed point in...

[Object] When press-bonding superposed curved glass plates together by a plurality of curved rolls, even if curvature of the curved glass changes, a preliminary bonding method and device of a laminated glass can cope with a variety of curvatures of the curved glass plate by an easy adjustment. [Means to solve] T...

Disclosed is a purification method of reducing and removing fluoride ions contained in an optically active α-fluorocarboxylic acid ester represented by formula [1] [Chemical Formula 30] [in the formula, R1 represents a C1-6 alkyl group, R2 represents a C1-4 alkyl group, and * represents an asymmetric carbon]...

Disclosed is a method for producing hexafluoroacetone monohydrate by (l) allowing, in an organic solvent, hexafluoroacetone to be absorbed into water or a hexafluoroacetone hydrate (water addition method) or by (2) an easy method in which a hexafluoroacetone hydrate is mixed with an organic solvent and then distilla...

ABSTRACT TITLE: PROCESS FOR PRODUCING α,α-DIFLUOROAROMATIC COMPOUNDS Disclosed is a process for producing an α,α-difluoroaromatic compound represented by the general formula [2]. This process includes the step of reacting 1-chloro-1-aromatic ring substituted ethene represented by the general formula [1] with h...

There is disclosed a method for producing a 4-deoxy-4-fluoro-D-glucose derivative by reacting a D-galactose derivative with either sulfuryl fluoride (SO2F2), trifiuoromethanesulfonyl fluoride (CF3SO2F) or perfluorobutanesulfonyl fluoride (C4F9SO2F) in the presence of an organic base or in the presence of an organ...

The present invention is capable of producing a fluorinated a ketocarboxylic ester hydrate by reacting a fluorinated a hydroxycarboxylic ester with "sodium hypochlorite or calcium hypochlorite the amount thereof being 21 mass% or larger with respect to the composition". Furthermore by reacting the hydrate with a deh...

Disclosed is a method for producing a compound having a difluoromethylene group at an even lower cost and with excellent yield. The production method of the present invention is a method for producing an aromatic difluoroacetic acid ester, which comprises reacting an iodobenzene containing an electroattracting group...

A fluoroamine can be produced by: protecting an amino group of an amino alcohol with a nitrobenzenesulfonyl group, thereby converting into a protected amino alcohol (amino group protection step); causing the protected amino alcohol to react with sulfuryl fluoride (SO2F2) in the presence of an organic base, thereby c...

This method for producing a ß-fluoroalcohol comprises a step wherein an ɑ-fluoroester is caused to react with a hydrogen gas (H2) in the presence of a specific ruthenium complex (one represented by general formula (2), especially one represented by general formula (4)). The production method is capable of employing ...

Provided is a process for producing a difluorocyclopropane compound under milder reaction conditions and with high selectivity and high yield. The disclosed process for producing a difluorocyclopropane compound is characterized by using sodium bromodifluoroacetate as a difluorocyclopropanation agent. With the disclo...

Disclosed is a method for producing monofluoro methane, which involves at least a pyrolysis step in which a 1-methoxy-1,1,2,2-tetrafluoro ethane is pyrolyzed by bringing same into contact with a catalyst, and a step for collecting monofluoro methane from the pyrolysis product. As a consequence, it is possible to eff...

Disclosed is a process for producing a protected optically active fluoroamine, which comprises the step of reacting an imine-protected optically active hydroxyamine, an oxazolidine-protected optically active hydroxyamine, or a mixture of the imine-protected optically active hydroxyamine and the oxazolidine-protect...

The disclosed method for producing difluoroacetyl chloride includes a chlorinating step that brings a difluoroacetyl fluoride composition containing at least difluoroacetyl fluoride into contact with calcium chloride at a temperature at which a reaction can take place. Also, the disclosed method for producing 2,2- d...

Disclosed is a preparation method for obtaining an alkali metal perfluorosulfinate by reacting a perfluoroalkane sulfinyl halide with a sulfur containing reducing agent in the presence of water, wherein mineral salts, which are an impurity in the solution, are precipitated and removed by concentrating a reaction m...

There is provided according to the present invention a process for producing fluoromethyl hexafluoroisopropyl ether ((CF3)2CH-O-CH2F), including: reacting bisfluoromethyl ether with hexafluoroisopropyl alcohol in a solvent substantially immiscible with hydrogen fluoride in the presence of a catalytic amount of a...

Halogenated α-fluoroethers (or bis-derivatives thereof) can be produced by reacting a halogenated hemiacetal (or bis-derivative thereof) with sulfuryl fluoride (SO2F2) in the presence of an organic base. The reaction is conducted preferably in the presence of "a salt or complex of an organic base with hydrogen f...

A fluorine-containing benzaldehyde is reacted with an alkyl Grignard reagent to convert it to a magnesium alkoxide of racemic, fluorine-containing, benzyl alcohol, and subsequently the magnesium alkoxide is reacted with phthalic anhydride to obtain a phthalate half ester of racemic, fluorine-containing, benzyl al...

It was found that a fluoro derivative can be produced by reacting a hydroxy derivative with sulfuryl fluoride (SO2F2) in the presence of an organic base or in the presence of an organic base and "a salt or complex comprising an organic base and hydrogen fluoride". According to the present production process, it ...

An optically active, fluorine-containing carbonyl-ene product is produced by reacting a fluorine-containing α ketoester with an alkene in the presence of a transition metal complex having an optically active ligand. There are Mode 1 of conducting this reaction in the absence of reaction solvent, Mode 2 of conducting...

An optically active α-fluorocarboxylate is produced by reacting an optically active α-hydroxycarboxylate with sulfuryl fluoride (SO2F2), trifluoromethanesulfonyl fluoride (CF3SO2F) or nonafluorobutanesulfonyl fluoride (C4F9SO2F) in the presence of organic base and in the absence of reaction solvent. More preferably,...

It is to provide a production method that the target fluorine-containing carboxylic acid ester can be obtained from a fluorine-containing ether by a one-step reaction, that a complicated step and a troublesome operation are not necessary, and that an excessive energy is not consumed. A fluorine-containirig carbo...

[Task] To provide a process for producing anhydrous hexafluoroacetone from hexafluoroacetone hydrate. To provide a process taking environment into consideration, that does not require a treatment of wastes, such as waste sulfuric acid, containing organic substances, which is inevitable in processes conducted hit...

There is disclosed a purification method of an optically active 1-(2-trifluoromethylphenyl)ethanol represented by the formula [1], which includes recrystallizing the optically active 1-(2-trifluoromethylphenyl)ethanol from an aliphatic hydrocarbon solvent where * denotes an asymmetric carbon. This method mak...

There is provided a novel, useful dehydroxyfluorination agent containing sulfuryl fluoride (SO2F2) and an organic base that is free from a free hydroxyl group in the molecule. According to the present dehydroxyfluorination agent, it is not necessary to use perfluoroalkanesulfonyl fluoride, which is not preferabl...

By reacting a β-hydroxy-α-amino acid with sulfuryl fluoride (SO2F2) in the presence of an organic base, it is possible to produce an α-fluoro-β-amino acid of the formula [2]. By using a C8-12 tertiary amine having two or more alkyl groups of C3 or higher, and especially diisopropylethylamine, as the organic base,...

An α-trifluoromethyl-α,β-unsaturated ester can be produced by reacting an α-trifluoromethyl-α-hydroxy ester with sulfuryl fluoride (SO2F2) in the presence of an organic base. It is preferable that the raw substrate has a hydrogen atom as one β-position substituent group and either an alkyl group, a substituted a...

[Problem] The purpose of the present invention is to provide: an antifouling article to which fine substances such as dust and dirt do not easily adhere and which has excellent removal performance of adhering fine substances, while exhibiting good antifouling properties and dirt removal properties even in cases when...

This lead free solder alloy for vehicle glass comprises an alloy composition of 26.0-56.0 mass% of In, 0.1-5.0 mass% of Ag, 0.002-0.05 mass% of Ti, and 0.001-0.01 mass% of Si, the remainder being Sn. Furthermore, the alloy may contain 0.005-0.1 mass% of Cu and 0.001-0.01 mass% of B. The solder alloy is particularly ...

[Problem] To provide a method for producing a highly pure difluoroacetic acid chloride composition product that at least contains difluoroacetic acid fluoride, using a simple means and a simple device. [Solution] A method for purifying difluoroacetic acid chloride, contains a step for causing a difluoroacetic acid c...

A method for preserving in an oxygen (O2) or inert gas atmosphere in an airtight container an aa-difluoroacetaldehyde alkyl hemiacetal represented by the formula in a gas-liquid state comprising a gas phase and a liquid phase characterized by comprising a step in which the oxygen concentration in the gas phase part ...

α-Trifluoromethyl-β-substituted-β-amino acids can be produced by allowing α-trifluoromethyl-β-substituted-α,β-unsaturated esters to react with hydroxylamine to convert α-trifluoromethyl-β-substituted-α,β-unsaturated esters into dehydrogenated closed-ring body of α-trifluoromethyl-β-substituted-β-amino acid, and ...

This process for producing fluorosulfuric acid aromatic-ring esters includes a step of reacting an aromatic-ring hydroxyl compound with sulfuryl fluoride (SO2F2) in the presence of a tertiary amine exclusive of pyridine and methylpyridine. Sulfuryl fluoride, which is used in the process, is widely used as a fumigant...

This method for improving the preservation stability of 2 2 difluoroacetoaldehyde comprises at least the following first step and second step. First step: a step in which a "2 2 difluoroacetoaldehyde alcohol composite" that contains a hemiacetal of 2 2 difluoroacetoaldehyde and surplus alcohol is prepared. The total...

In this method, a diastereomeric mixture containing a (2R)-2-fluoro-2-C-methyl-D-ribono-γ-lactone precursor is deprotected under acidic conditions; subsequently, by lactonizing the same, a diastereomeric mixture of dihydroxylactone is obtained; and subsequently, by purifying said mixture by recrystallization, high-p...

A purification method of desflurane (difluoromethyl-1, 2, 2, 2-tetrafluoroethyl ether represented by formula (1)) according to the present invention comprises a step wherein a mixture containing desflurane and a trihalomethane is brought into contact with a base in the presence of a phase transfer catalyst so as to ...

The present invention provides an industrially practicable method for producing a fluorine containing cyclopropane carboxylic acid compound that is useful as an intermediate for pharmaceuticals and agrochemicals. A fluorine containing cyclopropane monoester is obtained by: producing a fluorine containing cyclic sulf...

ABSTRACT TITLE: BASIC ALUMINUM CHLORIDE SOLUTION AND METHOD FOR         PRODUCING SAME A method for producing a basic aluminum chloride solution (target solution or high basicity PAC solution) includes the sequential steps of(a) adding an alkali to a basic aluminum chloride solution (raw solution or low basicit...

The production method for an aa-difluoroacetaldehyde hemiacetal ("DFAL-ROH") according to the present invention comprises: a step in which a difluoroacid ester is reacted with hydrogen (H2) in a reactor in the presence of a base and a ruthenium catalyst to produce a mixture containing a DFAL-ROH; a step in which the...

The present invention provides an industrially applicable method for production of a fluorine-containing cyclopropane carboxylic acid compound useful as an intermediate for pharmaceutical and agrichemical products. A fluorine-containing cyclopropane monoester is obtained by: forming a fluorine-containing cyclic sulf...

A 1 2 2 2-tetrafluorethyl methyl ether being a synthetic intermediate of desflurane was conveniently obtained by causing a trimethyl orthoformate to act on a fluoral obtained by a gas phase fluorination reaction of chloral in the presence of a catalyst. The obtained 1 2 2 2-tetrafluorethyl methyl ether can be induce...

This hydrochlorofluoroolefin-based novel composition contains Z-1-chloro-3,3,3-trifluoropropene, 1-chloro-1,3,3,3-tetrafluoropropane, and water. In this composition, the proportion of Z-1-chloro-3,3,3-trifluoropropene is 55.00-99.98 mass%, the proportion of 1-chloro-1,3,3,3-tetrafluoropropane is 0.01-44.99 mass%, an...

One problem addressed by the present invention is to provide a hydrofluoroolefin-based or a hydrochlorofluoroolefin-based azeotropic or azeotrope-like composition. This azeotropic or azeotrope-like composition contains trans-1-chloro-3,3,3-trifluoropropene and 1-chloro-1,3,3,3-tetrafluoropropene. In the azeotropic o...