Title of the Invention: SOLUBLE SALTS AND COCRYSTALS OF CLOTRIMAZOLE
ABSTRACT:
The present invention discloses new solid forms of the anti-mycotic drug Clotrimazole (CLT) with pharmaceutically acceptable coformers, such as 2,5-Dihydroxybenzoic acid (2,5DHBA), 2,4,6-Trihydroxybenzoic acid (2,4,6THBA), p-Coumaric ...
Disclosed herein is the synthesis of N-heterocyclic N-alkyl piperazine N-oxide derivatives for use in the treatment of type-2 diabetes mellitus (T2DM). The invention particularly discloses synthesis of N-oxide derivatives of Blonanserin, Clozapine, and Olanzapine. The present invention further discloses a process fo...
ABSTRACT:
The invention discloses novel co-amorphous solids of curcumin with naturally occurring molecules such as Artemisinin, Artesunate, Piperine, and cocrystals with Quercetin with improved bioavailability. The invention further relates to process for preparation of novel co-amorphous solids of curcumin-artem...
This invention discloses novel cocrystals of bioactive agent Andrographolide with GRAS coformers which inhibits chemical transformation of Andrographolide in in vitro conditions, improves solubility and dissolution rate of Andrographolide and enhances its bioavailabilty. The present invention further discloses the...