Formula (I) The invention relates to C 3 novel triterpenone with C 28 reverse amide derivatives related compounds and pharmaceutical compositions useful for the therapeutic treatment of viral diseases and particularly HIV mediated diseases.
The invention relates to a process for producing tablet compositions of etravirine comprising solid dispersion of etravirine, hydroxylpropyl methyl cellulose and optionally one or more pharmaceutically acceptable excipients, wherein the solid dispersion doesn"t contain microcrystalline cellulose.
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ABSTRACT:
Title: “Process for preparation of ((3R,11bR)-1,3,4,6,7,11b-Hexahydro-9,10-di(methoxy-d3)-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-one”
The present invention provides a process for preparation of deutetrabenazine using tetrabenazine as starting material.
"STABLE BILAYER TABLET COMPOSITIONS"
ABSTRACT:
The invention relates to stable bilayer tablet compositions comprising empagliflozin, linagliptin and pharmaceutically acceptable excipients which show no incompatibilities and the compositions having good stability and superior dissolution profile.
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DISPERSIBLE TABLET COMPOSITIONS OF DOLUTEGRAVIR
ABSTRACT
The present invention relates to dispersible tablet composition of dolutegravir sodium and one or more pharmaceutically acceptable excipients and process for preparation of such compositions.
TABLET COMPOSITIONS COMPRISING BICTEGRAVIR, TENOFOVIR ALAFENAMIDE AND EMTRICITABINE
ABSTRACT
The present invention relates to monolayer tablet compositions comprising bictegravir or a pharmaceutically acceptable salt thereof, tenofovir alafenamide or a pharmaceutically acceptable salt thereof, emtricitabine or...
STABLE ORAL LIQUID COMPOSITIONS OF ENALAPRIL
ABSTRACT
The present invention relates to pharmaceutical compositions of enalapril, particularly stable oral liquid compositions comprising enalapril, one or more buffering agents and at least one pharmaceutically acceptable excipient.
The present invention relates to pharmaceutical compositions of sacubitril and valsartan and a process for the preparation thereof. Particularly, the present invention relates to stable non-aqueous based tablet composition of sacubitril and valsartan and a process for the preparation thereof.
The present invention is directed to taste masked oral liquid suspension composition comprising resinate complex of solifenacin or a pharmaceutically acceptable salt thereof prepared by admixing palatable ingredients of differential polarities.
The present invention relates to novel triterpene derivatives of formula (I); and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, n, and ring (II) are as defined in formula (I). The invention also relates to novel triterpene derivatives, related compounds, and pharmaceutical compositions useful fo...
TABLET COMPOSITIONS OF ETRAVIRINE
ABSTRACT
The invention relates to tablet compositions of etravirine comprising hydroxypropyl methyl cellulose having a methoxy content of 25.0 - 32.0% (w/w), a hydroxypropoxy content of 22.0 - 27.0% (w/w) and a viscosity of 10.0 - 20.0 cps and process for preparing such tablet com...
The present invention relates to pharmaceutical compositions of lopinavir and ritonavir and process for preparation thereof. Particularly, the present invention relates to pharmaceutical capsule compositions of lopinavir and ritonavir and process for preparation thereof.
The present invention relates to process for preparing sartan drugs including intermediates thereof, which avoids formation of Nitrosoamine impurities.
The present invention relates to the efficient solid-phase synthesis of Aviptadil represented by Formula-I. The present invention relates to an efficient process for the preparation of Aviptadil by sequential coupling employing solid phase approach. It involves sequential coupling of protected amino acids to prepare...
TITLE: “AN IMPROVED PROCESS FOR PREPARATION OF ENCORAFENIB”
The present invention relates to an improved process for the preparation of Encorafenib represented by Formula (I). The present invention relates to cost-effective and eco-friendly process for preparation of Encorafenib.
The present invention relates to novel triterpenone derivatives of formula (I); and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5 and R6 are as defined herein. The invention also relates to novel triterpenone derivatives, related compounds, and pharmaceutical compositions useful for the thera...
The present invention relates to novel triterpene derivatives of formula (I); and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, and ring are as defined herein. The invention also relates to novel triterpene derivatives, related compounds, and pharmaceutical compositions useful for the therapeuti...
The invention relates to a stable pharmaceutical liquid composition comprising lisinopril or its pharmaceutically acceptable salt thereof and one or more pharmaceutically acceptable excipients and process of its preparation.
The present invention relates to an improved process for the preparation of Voxelotor and its key intermediate (2-(1-Isopropyl-1H-pyrazol-5-yl)pyridin-3-yl)methanol
The present invention relates to Amorphous Lenacapavir Sodium solid dispersion and its process for preparation thereof. The amorphous Lenacapavir Sodium solid dispersions of the present application can be reproduced easily and is amenable for processing into a dosage form.
The present invention relates to an improved process for preparation of Cabozantinib S-malate, which comprises of reacting 4-[(6,7-dimethoxy-4-quinolyl)oxy]aniline compound of formula IV and 1-[(4-fluorophenyl)carbamoyl]cyclopropane carboxylic acid compound of formula-V in presence of Propanephosphonic acid anhydrid...
The present invention relates to Amorphous solid dispersion of Acalabrutinib maleate with a suitable pharmaceutically acceptable excipient selected from a group consisting of hydroxyl propyl cellulose (HPC), hydroxyl propyl methyl cellulose (HPMC), hydroxyl propyl methyl cellulose – acetate succinate (HPMC-AS), Povi...
The present invention is directed to an improved, industrially viable, cost-effective process for the industrial manufacturing of enantiomerically pure (S,S)-2,8-diazabicyclo[4.3.0]nonane of Formula I which is used as an intermediate in the preparation of Moxifloxacin.
The present invention relates to process for preparation of Trilaciclib or its pharmaceutical acceptable salts, which comprises condensing Chloro-7’,8’-dihydro-6’H-spiro[cyclohexane-1,9’-pyrazino[1’,2’:1,5]pyrrolo[2,3-d]pyrimidin]-6’-one compound of formula IV with 5-(4-Methylpiperazine-1-yl)pyridine-2-amine compoun...
The present invention relates to a process for preparation of oxygen linked pyrimidine derivative, useful as anti-proliferative agent (Pacritinib), its pharmaceutically acceptable salts and intermediates thereof.
The present invention relates to a process for the preparation of Lenacapavir or its
pharmaceutically acceptable salts, wherein involves propylphosphonic anhydride as
amide coupling reagent.
TITLE: “An improved process for preparation of Zastaprazan”
The present invention relates to an improved process for preparation of Zastaprazan or its pharmaceutically acceptable salts, which comprises: a) reaction of methyl 5,6-diaminonicotinate and 3-bromobutan-2-one to obtain methyl 8-amino-2,3-dimethyl imidazo[...
TITLE: “An improved process for preparation of Elacestrant or its dihydrochloride salt”
The present invention relates to an improved process for preparation of Elacestrant or its pharmaceutically acceptable salts, which comprises: a) reacting the compound of Formula II
with the compound of Formula III to obtain co...