Abstract Of The Invention
The present invention relates to a novel and improved process for the preparation of Sitagliptin of Formula I and its pharmaceutically acceptable salts.
The present invention also relates to novel intermediates and process for the preparation of intermediates used in the preparation o...
The present invention relates to a new process for preparing the
oxazolidinone antibacterial agent Linezolid including key intermediates of
oxazolidinones, which comprises the following reactions.
Step (a): Reacting 3-fluoro-4-morpholinyl aniline with R-epichlorohydrin
Step (b): Carbonylation to form oxazolidino...
The invention relates to a novel process for preparation of crystalline Linezolid Form-III. The crystalline Linezolid Form-III obtained by the process is highly pure with HPLC purity equal to or greater than 99.9% with single un-known impurity less than 0.05%.
NOVEL OXAZOLIDINONE COMPOUNDS
A novel oxazolidinone compound (S)-N-((3-(4-fluoro-3-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide of formula –I and a process for the preparation thereof.
Compound-I
A commercially viable process for industrial preparation of [(S)-n-tert butoxycarbonyl-3-hydroxy]adamantylglycine which is a key intermediate for saxagliptin synthesis and is represented by compound of Formula-VI. The compound-VI obtained by the process of present invention has more than 99.5% HPLC purity not more ...
The invention relates to the process of obtaining novel polymorphic form of Voriconazole. Voriconazole has the chemical name (2R, 3S)-2-(2,4-difluorophenYl)-3-(5-fluoropyrimidin-4-yl)-l-(lH-l,2,4-triazol-yl)-butan-2-ol represented as Formula (I)
To,
Controller of Patents Patent Office Branch IPR Building, GST R...
Disclosed herein is a cost effective and industrially feasible process for the preparation of clopidogrel bisulphate. The present invention further discloses a novel method of precipitation of clopidogrel bisulphate form 1 directly from solvent mix of methanol and acetone in presence of sulfuric acid at a temperatu...
An improved method for the synthesis of omeprazole form A, comprising the steps of reacting 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methylthio]-1H-benzimidazole in methanol with hydrogen peroxide in presence of a mixture of ammonium molybdate and ammonium dihydrogen ortho phosphate, resulting in crude form...
The present invention provides a process for the preparation of substituted 2-(2-pyridylmethyl) sulphinyl-1H-benzimidazoles a compound comprising the steps of
a) thio compound is oxidized with an oxidizing agent in presence of alcohol,
b) extraction and followed by an isolation in halogenated hydrocarbon,
c) f...
Disclosed herein is process for preparation of crystalline form of (S)-5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methyl]sulfinyl]-lH-benzimidazolemagnesium dihydrate which comprises: dissolving (S)-Omepra2ole potassium in dimethyl formamide; reacting with magnesium chloride hexa hydrate; removing the salts ...
A commercially viable process for industrial preparation of trans-(1R,2R)-cyclohexane 1,2–dicarboxylic acid represented by compound of Formula-I, wherein the compound has more than 99% HPLC purity. The compound of Formula-I is a key intermediate in preparation of Lurasidone hydrochloride which is a well known antips...
A novel oxazolidinone antibacterial compound [(S)- N- [[3-[4-fluoro-3-morpholino phenyl]-2-oxooxazolidin-5-yl] methyl] acetamide] of Formula-I and its broad spectrum antibacterial activities against a large number of gram positive and gram negative pathogens is disclosed.
Compound-I
ABSTRACT
The present invention relates to stable amorphous form of pharmaceutically acceptable salt of a dipeptidyl peptidase-4 (dpp-4) enzyme inhibitor. The present invention specifically relates to stable amorphous form of pharmaceutically acceptable salts of Sitagliptin. The present invention more specifically r...
ABSTRACT
NOVEL PROCESS FOR PREPARATION OF ANTIHISTAMINE AGENT INTERMEDIATES AND USES THEREOF
The present invention relates to novel process for the preparation of intermediate compounds used in the preparation of Antihistamine agents. The present invention particularly relates to novel process for the preparation ...
ABSTRACT
STABLE AMORPHOUS FORM OF POTASSIUM –COMPETITIVE ACID BLOCKER AND PROCESS FOR THE PREPARATION THEREO
The present invention provides a stable amorphous Tegoprazan of the formula (I). The present invention provides stable amorphous Tegoprazan free from other solid state forms and stable over shelf life and...
ABSTRACT
AN IMPROVED PROCESS FOR THE PREPARATION OF GABAPENTINOID
The present invention relates to an improved process for the preparation of compound, 2-((1R,5S,6S)-6-(aminomethyl)-3-ethylbicyclo[3.2.0]hept-3-en-6-yl)acetic acid used in the preparation of Mirogabalin Besylate. The present invention specificall...
ABSTRACT
AN IMPROVED PROCESS FOR THE ENANTIOSELECTIVE PREPARATION OF FINERENONE INTERMEDIATE COMPOUND
The present invention relates to an improved process for the enantioselective Finerenone intermediate compound of Formula (I) used in the preparation of Finerenone. The present invention specifically relates t...
ABSTRACT
AN IMPROVED PROCESS FOR THE PREPARATION OF RESMETIROM FORM I
The present invention relates to an improved process for the preparation of Resmetirom Crystalline Form I. The present invention relates to an improved process for the preparation of Resmetirom Crystalline Form I free from other solid state form...