Disclosed herein is an improved process for the preparation of Budesonide using Perchloric acid catalyst in water as a major medium.

The invention discloses an improved process for the preparation of Methyl testosterone of formula III by ring opening of epoxide of formula-I using a reducing agent and subsequent deprotection at 3-position.

The present invention discloses economical and commercial manufacturing process of Methylprednisolone Aceponate and its purification.