The present invention provides design and composition of custom outer membrane Protein LipL32 mRNA (isoforms 1-15) sequences oligonucleotide primers sequences for diagnosis of Leptospira interrogans and mRNA based Human and Veterinary Vaccine against Leptospirosis with improved activity. The disclosed oligonucleotid...

The present invention provides design of F-Spondin peptide for treatment of Alzheimer’s with improved pharmacokinetic activity. The disclosed peptide is amino acid sequence with further modification to treat Alzheimer’s.

The present invention provides design of synthetic long acting analogs of human glucagon with improved pharmacokinetic activity. The disclosed glucagon analog polypeptides are particularly useful in methods of treating metabolic diseases such as type 2 diabetes, weight loss and obesity.

To design mRNA sequence comprises of 21 amino acids signal peptide at N-terminus, 21 amino acid transmembrane domains and 43 amino acid cytoplasmic domains. In the present invention mRNA sequence comprises a coding region encoding at least one antigenic protein for treatment and prevention of rabies virus infection....

The present invention provides to develop novel chimeric antigen receptor (CAR) encoded by an open reading frame 3 (ORF3) mRNA and amino acid sequences of any one of SEQ ID NO: 1 to SEQ ID NO: 109 specific to CD19 against hematologic malignancies associated with expression of Cluster of Differentiation 19 (CD19). Th...