The present invention relates to active esters of compound of Formula I-A and Formula I-B which are used as key intermediates in the synthesis of Micafungin, an antifungal agent and process of preparation of said active esters. The invention also relates to process of preparing Micafungin from said active esters. ...

The present invention relates to intermediate compounds which are used as key intermediates in the synthesis of Romidepsin and process of preparation of these intermediates. The present invention also provides processes for synthesis of Romidepsin in high purity and good yields from said intermediate compounds. ...

A novel process for preparation of Deutetrabenazine ((RR, SS)-l,3,4,6,7-llb-Hexahydro-9,10-di(methoxy-d6)-3-(2-methylpropyl)-2H- benzo [a] quinolizin-2-one) of formula I comprises of methylation of N-(2-(3,4-dihydroxy-phenyl)-ethyl)-formamide compound of formula III with deuteriated methanol (CD3OD or CD3OH) to obta...

A novel process for the preparation of Lifitegrast of the present invention discloses a preparation method of a Lifitegrast and its novel intermediate. The present invention the novel process for preparation of Lifitegrast ((S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3...

ABSTRACT: The present invention relates to improved manufacturing process for preparing Degarelix Acetate using method of deprotection in solid phase peptide synthesis in which the improvement comprises: treating with Pyrrolidine in Dimethylformamide in small volume. Also disclosed is degarelix of high purity p...

The invention relates to an improved process for preparation of Midostaurin. In one aspect of the invention, to a new process for purifying Midostaurin

The present invention relates to a process for preparation of 6-perdeoxy-6-per-chloro gamma-cyclodextrin which is a key intermediate useful in the synthesis of Sugammadex sodium. The present invention further relates to a process for preparation and purification of Sugammadex sodium.

Title – A METHOD FOR PREPARING GLP-1 ANALOGUE BY SOLID-PHASE PEPTIDE SYNTHESIS ABSTRACT The present invention relates to improved process for manufacturing of glucagon-like peptide-1 (GLP-I) and analogs by utilizing Fmoc protected amino acids and synthesizing peptide by solid phase method. The present invention ...

TITLE – A NOVEL PROCESS FOR SYNTHESIS OF CARBETOCIN OCTAPEPTIDE ABSTRACT The invention provides a solid-phase synthesis (SPPS) method of Carbetocin, and the method comprises the following steps of: sequentially coupling amino acid containing Fmoc (fluorenylmethoxycarbonyl) protecting group by Rink Amide Resi...

TITLE - A PROCESS FOR THE PREPARATION OF PARATHYROID HORMONE ANALOG. ABSTRACT The present invention relates to a process for preparing Abaloparatide by the Solid Phase Process Synthesis (SPPS). The said process employs protected amino acids thereby avoiding problems related to aggregation of peptides on to the ...

TITLE: A NOVEL PROCESS FOR PREPARATION OF REMDESIVIR. ABSTRACT A novel process for the preparation of 2-Ethylbutyl (2S)-2-{[(S)-{[(2R,3S,4R,5R)-5-(4- aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl]methoxy} (phenoxy) phosphoryl] amino} propanoate of formula I (remdesivir) ...

The invention relates to an improved process for the preparation of Saroglitazar. In particular, the invention relates to an improved process for the preparation of Saroglitazar comprising condensation of 2-[2-methyl-5-(4-methylsulfanyl-phenyl)-pyrrol-1-yl] derivate compound of formula II and 2-ethoxy-3-(4-hydroxy-p...

TITLE – AN IMPROVED PROCESS FOR THE PREPARATION OF SAROGLITAZAR CALCIUM ABSTRACT The invention relates to an improved process for the preparation of Saroglitazar calcium. In particular, the invention relates to an improved process for the preparation of Saroglitazar calcium comprising condensation of 2-(2-me...

A Stable pharmaceutical composition for an injectable preparation containing Brexanolone for injection and preparation method thereof. The present invention more particularly relates to pharmaceutical composition more particularly, injectable preparation of Brexanolone for intravenous application. The present invent...