The present invention provides an improved process for the preparation of 8-chloro-l-phenyl-lH-benzo[b][l,4]diazepine-2,4(3H,5H)-dione (hereafter referred to as the compound (IV)), which is useful as a key intermediate for the synthesis of Clobazam (referred to as the compound (I)) 7-chloro-l-methyI-5-phenyl...
The present invention provides an improved process for the preparation of (5-amino-2-butylbenzofuran-3-yl)(4-(3-(dibutylamino)propoxy)phenyl)methanone (referred to as the compound-II) and/or salts thereof, which is useful as a key intermediate for the synthesis of Dronedarone;N-{2-butyl-3-[4-(3-dibutylaminop...
The present invention provides an improved process for the preparation of Mebeverine [4-(ethyl(l-(4-methoxyphenyl)propan-2-yl)amino)butyl 3,4-dimethoxybenzoate] or a pharmaceutically acceptable salt thereof and its intermediates. The process comprises use of compound (VI), obtained from compound (V) for the ...
ABSTRACT
DELAYED RELEASE PHARMACEUTICAL COMPOSITION OF PREDNISONE AND PREPARATION THEREOF
The present invention relates to a delayed-release pharmaceutical composition comprising an active ingredient prednisone and one or more pharmaceutical excipient(s). The invention further relates to a process for preparat...
ABSTRACT
PRESS-COATED PREDNISONE TABLETS AND PROCESS FOR ITS PREPARATION
The present invention relates to a press-coated pharmaceutical composition having a core comprising of an active ingredient prednisone and one or more pharmaceutical excipient(s) and a coating comprising a coating agent and one or more ph...
ABSTRACT
AN IMPROVED PROCESS FOR 4-(HYDROXYMETHYL)-5-METHYL-1,3-DIOXOL-2-ONE
The present invention relates to an improved process for 4-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-one (I). The process involves reaction of compound of formula (II) with sodium acetate in presence of catalytic amount of potassium iod...
ABSTRACT
AN IMPROVED SUBSTRATE COCKTAIL ASSAY FOR HIGH-THROUGHPUT SCREENING OF CYTOCHROME P450 INHIBITORS
The present invention relates to obtaining single incubation condition for cocktail of probe substrates of 8 major Cytochrome P450 (CYP) isoforms to assess in vitro drug-drug interactions (DDIs) of novel...
Abstract
STABLE SOLID FORMULATION OF AZILSARTAN OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF
The present invention relates to a stable, solid composition of Azilsartan or its pharmaceutically acceptable salts thereof and one or more pharmaceutically acceptable excipient(s); optionally, the said composition fur...
ABSTRACT
PROCESS FOR THE PREPARATION OF ANAGRELIDE HYDROCHLORIDE MONOHYDRATE
The present invention relates to an industrially feasible and economically viable process for preparation of Anagrelide Hydrochloride Monohydrate of formula (1a).
ABSTRACT
A PROCESS FOR PREPARATION OF DEXMEDETOMIDINE HYDROCHLORIDE
The present invention discloses an improved process for preparation of Dexmedetomidine hydrochloride (1a) which overcomes the problems associated with prior art and provides the preparation of dexmedetomidine hydrochloride in desired yield an...
The present invention provides an improved process for the preparation of 4-((2-isopropoxy ethoxy) methyl) phenol compound (I), used as an intermediate in many organic synthesis; particularly a key intermediate for the synthesis of l-[4[2(l-methylethoxy) ethoxy methyl] phenoxy]-3-(l-methylethylamino)-propan-...
ABSTRACT
AN IMPROVED PROCESS FOR THE PREPARATION OF VORTIOXETINE AND SALTS THEREOF
The present invention relates to a novel crystalline polymorphic form of 1-[2-(2,4-dimethyl-phenylsulfanyl)-phenyl]-piperazine hydrochloride; commonly known as vortioxetine hydrochloride (hereafter referred to as the compound (I...
The present invention relates to a method of evaluating the audit readiness of a pharmaceutical manufacturing site. The method provides for converting an intangible measurement of quality culture in an organization to a tangible value via quantification and hence predicting of audit /inspection.
...
MONITORING COMPLIANCE OF PHARMACEUTICAL MANUFACTURING SITES
The present invention relates to a method of evaluating data integrity (DI) compliance of a pharmaceutical manufacturing site. The method provides quantified measurement of data Integrity compliance of manufacturing site.
A PROCESS FOR PREPARATION OF INTERMEDIATE OF EDOXABAN
The present invention relates to an industrially feasible and economically viable process for preparation of Edoxaban key intermediate viz. compound of formula (1) which is shown below:
To,
The Controller of Patents
The Patent Office
At Mumbai
...
ABSTRACT
AN IMPROVED PROCESS FOR THE PREPARATION OF
ELTROMBOPAG OLAMINE
The present invention relates to an improved process for the preparation of Eltrombopag olamine
intermediates and further conversion to Eltrombopag olamine of a compound of formula (2).
To,
The Controller of Patents...
ABSTRACT
PROCESS FOR THE PREPARATION OF ETORICOXIB
The present invention relates to an improved process for the preparation of Etoricoxib (1).
To, The Controller of Patents ...
ABSTRACT
A PROCESS FOR THE PREPARATION OF
LEVOKETOCONAZOLE
The present invention relates to a process for the preparation of Levoketoconazole (1). It further provides a process for the preparation of crystalline anhydrous Levoketoconazole (1).
ABSTRACT
A PROCESS FOR THE PREPARATION OF BILASTINE
The present invention relates to a process for the preparation Bilastine (1). The process produces Bilastine (1) with greater than or equal to 99.9 % purity.
To,
The Controller of Patents
The Patent Office
At Mumbai
...
ABSTRACT
METHOD FOR PURIFICATION OF LEUPRORELIN OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF
The present invention provides an improved process for purification and isolation of leuprorelin or pharmaceutically acceptable salt(s) thereof by preparative supercritical fluid chromatography (preparative SFC) method...
ABSTRACT
AN IMPROVED ONE-POT PRECESS FOR THE PREPARATION OF 5-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE
The present invention relates to an improved one-pot process for the preparation of 5-methyl-3-(trifluoromethyl)-1H-pyrazole of formula (1).
ABSTRACT
A NOVEL PROCESS FOR THE PREPARATION OF 1-(2-(5-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL) ACETYL) PIPERIDINE-4-CARBOTHIOAMIDE
The present invention relates to a process for the preparation of 1-(2-(5-methyl-3-(trifluoromethyl)-1h-pyrazol-1-yl) acetyl) piperidine-4-carbothioamide (1).
To,
...
ABSTRACT
TELESCOPIC SYNTHESIS OF BRIVARACETAM
The present invention relates to a telescoping process for the preparation of brivaracetam. The process according to the present invention is a cost effective process in that it avoids isolation of intermediates at every step.
ABSTRACT
A PROCESS FOR THE PREPARATION OF LIRAGLUTIDE
The present invention relates to a process for preparing Liraglutide by solid phase peptide synthesis (SPPS). It describes a convergent synthesis by using different fragments including pseudoprolines in one or more of the fragments bound to a solid support....
A PROCESS FOR THE PREPARATION OF SEMAGLUTIDE
The present invention relates to a process for preparing Semaglutide by solid phase peptide synthesis (SPPS). It describes a convergent synthesis by using different fragments including pseudoprolines in one or more of the fragments bound to a solid support.
...
[Class : 31] Foodstuffs And Beverages For Animals; Aromatic Sand [Litter] For Pets; Beverages For Pets; Pet Food; Sand For Pet Toilets; Sanded Paper [Litter] For Pets; Dog Biscuits.
[Class : 5] Pharmaceuticals, Medical And Veterinary Preparations; Sanitary Preparations For Medical Purposes; Dietetic Food And Substances Adapted For Medical Or Veterinary Use, Food For Babies; Dietary Supplements For Human Beings And Animals; Diapers For Pets; Disposable Absorbent Pads For Lining Pet Crates / Disposable Absorbent Mats For Lining Pet Crates; Disposable Hou...
[Class : 3] Non Medicated Cosmetics And Toiletry Preparations; Non Medicated Dentifrices; Perfumery; Essential Oils; Bleaching Preparations And Other Substances For Laundry Use; Cleaning; Polishing ; Scouring And Abrasive Preparations; Deodorants And Shampoos For Pets; Pet Wipes; Bathing And Grooming Hand Brush; Hygiene Set.
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Standard Chartered Bank
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The Hongkong And Shanghai Banking Corporation Limited
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