The present disclosure relates generally to lipid nanoparticle compositions comprising a nucleic acid an ionizable polymer a cationic lipid a phospholipid a sterol and a PEG lipid. Further the present disclosure relates generally to methods of treating or preventing a disease comprising administering to a sub...

The present disclosure relates generally to nucleic acids comprising a plurality of polynucleotide sequences wherein each polynucleotide sequence of the plurality comprises a target sequence a linker sequence and a self assembling sequence or a linker sequence a target sequence a linker sequence and a self as...