The invention relates to MCT absorbate composition comprising MCT oil, inorganic silicate substrate and at least one excipient which is acceptable in nutraceutical, food and pharmaceutical industry. More preferably MCT absorbate as described herein, is comprised of calcium silicate and at least one excipient selecte...
The present invention relates to solid oral pharmaceutical compositions comprising amorphous dapagliflozin. The invention further relates to a process for the preparation of the said pharmaceutical compositions. The said compositions are administered orally for the treatment of diabetes mellitus. The said compositio...
The present invention relates to compositions comprising one or more curcuminoids, and at least one dissolution enhancer. The said compositions exhibit improved dissolution and are substantially free of surfactants. The said compositions are stable and orally bioavailable. The present invention also provides a proce...
The present invention relates to a melt composite comprising one or more curcuminoids and a carrier selected from rice bran extract, mannitol, maltodextrin and mixtures thereof. The invention also provides a process for preparation of the melt composite, wherein the mixture of curcuminoids, rice bran extract, mannit...
The invention describes a non-staining composition comprising high content of curcuminoids in granular form, which is substantially free of excipients and is comprised of at least about 94% of curcuminoids. The non-staining composition may be comprised of 0 to 5% by weight of excipients, which are used as processing...
The present invention provides stable, solid dosage forms for co-administration of two or more, incompatible, active agents wherein one active agent is a polyphenol such as resveratrol and the other active agent is a transition metal ion such as copper. The present invention also provides a process for the preparati...
The invention describes a gut-protective composition comprising boswellic acid, at least one pH modifier, wherein the composition exhibits enhanced dissolution. The composition as described herein may be comprised of about 5 to 95% of boswellic acid. The said composition is stable and exhibits improved bioavailabili...
The present invention provides a solid, non-hygroscopic curing agent in a powdered / granular form easy to use, handle and optionally reconstitute, comprising a plant-based nitrite derived from a concentrated liquid extract obtained from plant material selected from Beet, radish, onion, celery and chicory leaf. In p...
The present invention relates to stable, room-temperature storable, liquid compositions comprising posaconazole. The liquid compositions, when stored at room temperature conditions, exhibit no significant coloration and no significant loss in chemical stability. The liquid compositions also exhibit good dilution sta...
The present invention relates to non-granulated compositions comprising rivaroxaban for oral administration, wherein rivaroxaban is at a concentration of not more than 20% by weight of the composition. The said non-granulated compositions provide the desired dissolution, and storage stability of rivaroxaban, and are...
The present invention relates to solid oral pharmaceutical compositions comprising amorphous dapagliflozin. The invention further relates to a process for the preparation of the said pharmaceutical compositions. The said compositions are administered orally for the treatment of diabetes mellitus. The said compositio...
The invention relates to granular psyllium formulation comprised of 10 to 60% by weight of gelation retardant, which exhibits delayed gelation property. The invention also relates to the process for preparation of granular formulation, wherein psyllium husk is treated with at least one gelation retardant and optiona...
The present invention provides a solid, non-hygroscopic water-soluble curing agent in a powdered / granular form easy to use, handle and optionally reconstitute, comprising a plant-based nitrite derived from a concentrated liquid extract obtained from plant material selected from celery. In particular, it relates to...
The present invention relates to a non-colouring turmeric formulation comprised of a blend of turmeric powder and curcumin extract, combined with at least about 10 to 25% by weight of a non-polymeric encapsulating agent and at least one excipient. The formulation may be comprised of blend of turmeric powder and curc...
The present invention relates to a prolonged release formulation of caffeine, which comprises of caffeine embedded in a continuous phase of non-polymeric release controlling carrier. The formulation may be optionally comprised of one or more excipients which are acceptable in nutraceutical and food industry. The inv...
ANGIOTENSIN RECEPTOR BLOCKER (ARB) COMPOSITIONS
The present invention relates to stable, oral compositions comprising at least one angiotensin II receptor blocker (ARB), wherein the ARB is non-granulated. The present invention also relates to stable compositions for oral co-delivery, comprising at least one ARB and...
Abstract
The invention relates to modified release granular composition comprising melatonin and at least one non-swelling release controlling agent. The matrix granular composition as described herein may be specifically comprised of about 1 to 70% by weight of melatonin and about 10 to 70% by weight of non-swelli...
Abstract
The invention relates to stable prolonged release vitamin C formulation, which is free of any added stabilizer and exhibits prolonged release of the active. The formulation is comprised of at least one hydrophobic non-polymeric excipient and hydrophilic release controlling agent along with at least one exc...
Title of the invention: Modified Release Formulation comprising Withanolides
Abstract
The invention describes a modified release formulation comprising 2 to 10% withanolides, obtained from root powder of Withania somnifera. The formulation is comprised of at least one pH independent release controlling agent o...
The present invention relates to stable, oral, non-granulated, rapid release compositions comprising varenicline and at least one excipient. The non-granulated compositions are in the form of powder blends, directly compressed tablets, or capsules. The present invention also provides a process for the preparation of...
The present invention relates to dosage forms comprising bead compositions of acotiamide for oral administration, wherein the bead composition comprises a core and at least one coat. The bead compositions exhibit immediate release and/or modified release of acotiamide. The oral dosage form may further comprise at l...
The present invention relates to photostable and room-temperature storable liquid compositions of sugammadex. The sugammadex liquid compositions comprise sugammadex and a vehicle, and have a dissolved oxygen content of less than about 3 ppm. In preferred liquid compositions, the dissolved oxygen content of the liqui...
The present invention relates to storage-stable pharmaceutical compositions comprising a drug substance containing amine, and at least one excipient, wherein the nitrosamine impurities in the said compositions are within acceptable levels. The nitrite content of the storage-stable pharmaceutical compositions is not ...
The present invention relates to stable, lyophilized compositions comprising parecoxib, for parenteral administration. The lyophilized compositions are capable of being reconstituted in a suitable reconstitution diluent to obtain liquid parecoxib compositions, the said liquid compositions having an in-use stability ...
The present invention relates to layered tablet compositions comprising a dipeptidyl peptidase-4 (DPP-4) inhibitor such as teneligliptin, and a sodium glucose cotransporter (SGLT) inhibitor such as dapagliflozin. The said layered tablet compositions comprise lubricant in a concentration of not more than 2% by weight...
The present invention relates to rapid release compositions comprising a granular component, wherein the granular component comprises amifampridine phosphate. The present invention also provides a process for the preparation of such compositions.