The present disclosure is directed to chemically stable and pharmaceutically acceptable sildenafil oral spray formulations for the treatment of diseases such as pulmonary arterial hypertension and/or SSRI induced sexual dysfunction wherein the oral spray formulation has a pH of about 1.5 to less than 3.0. The present ...

A method to increase the penetration of active agents through mucosal membranes the method comprising the step of: a) administering to a subject in need a composition comprising: i) one or more hydrotropes in a total amount of less than 15% by weight of the composition; and ii) an active agent with a partition co-ef...