ABSTRACT
The present invention relates to an improved and industrially advantageous process for the preparation of 5-methyl-3-pyridine methanol or its salts of Formula I.
This compound is a key intermediate in the synthesis of Rupatadine, an antihistaminic agent.
The present invention relates to identification, synthesis and structural studies of new rearranged impurity 3-(methylsulfonyl)-10H-phenothiazine in novel crystalline Form of Metopimazine.
The present invention provides an improved process for producing an optically active quinuclidinol. More preferably, the present invention provides process for preparation of optically active quinuclidinol by resolution of racemic 3-quinuclidinol using a chiral acid.
An improved process for the preparation of N-methylpentylamine which comprises reacting 1-halopentane of formula (II)
wherein X represents halogen atom with methylamine using a solvent, wherein the reaction is carried out in the absence of base.
1. An improved process for the preparation of palonosetron hydrochloride, comprising the steps of:
a) hydrogenating the salt of 2-(l-azabicyclo[2.2.2]oct-3-yl)-2,4,5,6-tetrahydro-lH-benz[de]isoquinolin-l-one of formula (II)
wherein x represents salt, using hydrogenation catalyst, in water to obtain p...
Abstract
The present invention relates to an improved process for reducing esters. Particularly, the present invention relates to an improved process of reducing esters of organic compounds into corresponding alcohols. More particularly the present invention relates to preparation of cyclic alcohols of compound of ...
This invention relates to a process for the preparation of "Cinacalcet
Hydrochloride and its key intermediate 3-[3-
(triflurornethyl)phenyl]propionaldehyde", the said process comprises reductive animation of3-[3-(trifluromethyl)phenyl]propionaldehydeand (R)-(l -napthyl ethylamine) in presence of activated sodium b...
This invention relates to a process for the preparation of N-benzyl-4-formylpiperidine, a key intermediate used in the synthesis Donepezil. The said process comprises of decomposition of compound of formula VII in the presence of base. This invention also provides a process for preparing a compound of formula VII, s...
This invention relates to a process for the preparation of 3-Quinuclidinone(III), a key intermediate used in the synthesis of Quinuclidinol based drugs.. The said process comprises of decomposition of compound of formula VII in the presence of base. This invention also provides a process for preparing a compound of ...
The present invention relates to an improved process for the preparation of Tenofovir. More particularly the present invention relates to the preparation of Tenofovir disoproxil fumarate.
The present invention provides a novel high melting crystalline Form of Metopimazine. Further, the present invention also provides a process for preparing novel high melting crystalline Form of Metopimazine.
Abstract
The present invention relates to an improved process for the preparation of Cinacalcet of Formula I.
More particularly, the present invention relates to the process for the preparation of 1-(naphthalen-5-yl)ethanamine or its salts of Formula II which are used as intermediates in the preparation of C...
The present invention relates to a process for the preparation of indoline derivatives and salts thereof. In particular the present invention relates to process for the preparation of indoline derivative and salts thereof which may be used as intermediates in the preparation of alpha-1 adrenergic receptor antagonist...