Disclosed is a process for preparing ß-agonist, 1-(4-amino-3, 5-dichlorophenyl)-2-(tert-butylamino) ethanol, of Formula I. The process comprises refluxing 1-(4-amino-3, 5-dichlorophenyl) ethanone of Formula II and selenium dioxide in the presence of 1, 4-dioxane to form compound of Formula III. Further, compound of...
The present invention relates to an improved process for synthesis of dexadreson glucocorticoid. The process includes the steps of a) preparation of 9a-fluoro- llß, 17a, 21-trihydroxy-16a-methylpregna-1, 4-diene-3, 20-Dione (I) by ring opening; b) preparation of dexamethasone 21-Methanesulfonate (II) by esterificati...