The invention relates to an in-situ process for the preparation of amoxicillin trihydrate from sugarcane juice without isolation of the intermediates produced during the reaction sequence viz penicillin G and 6-aminopenicillanic acid. The invention provides an in-situ cost effective and environment friendly proce...

The present invention relates to a process for the preparation of isoxazolyl penicillins from sugarcane juice. The invention focuses on in-situ synthesis of isoxazolyl penicillins without isolation of the intermediates like Penicillin G and 6-APA from the reaction sequence.

An improved process for preparing ascorbic acid, wherein the said process involves the reaction of 2-keto-L-gulonic acid with an aldehyde in the presence of an inert solvent and an acid chloride.

The present invention discloses a novel process for determination of gabapentin without derivatization in bulk, pharmaceutical formulations and human urine samples by HPLC using UV detector. The same has been achieved by optimization of isocratic mobile phase, appropriate column use and HPLC performance conditions. ...

The present invention discloses a novel process for synthesis of pure Sodium 2-ethyl hexanoate which is simple, fast, cost effective, less energy consuming and more efficient. The same has been achieved by dehydrating the aqueous solution of salt and subsequent drying in a pan to obtain purified salt in fine powdere...

The invention relates to a novel process for the direct estimation of pregabalin in bulk pharmaceuticals, formulations and human urine samples with the help of High Performance Liquid Chromatography system (HPLC) using UV detector and without the need for derivatization, thus enabling fast and easy analysis of sampl...

An improved process for preparing sterile amoxicillin and an alkali metal salt thereof, wherein the said process involves the steps of: i) dissolving amoxicillin trihydrate in methyl acetate, methanol and triethylamine; ii) Passing the resulting solution through a series of filters iii) addition of mixture of sodium...

An improved process for the production of penicillins, preferably amoxicillin trihydrate, having a low concentration of halogen-containing solvents. The reaction is carried out in the presence of vacuum and simultaneous purging of an inert gas which results in lowering the concentration of solvent as an impurity pre...

The present invention relates to an improved process for the preparation of isoxazolyl penicillins of formula (I). wherein X1 and X2 can be independently selected from the group comprising hydrogen, chlorine or fluorine, and its pharmaceutically suitable salts. The invention also focuses on an in-situ synthes...

The invention relates to a process for preparation of a premixed form of piperacillin and tazobactam. The admixture is prepared by dissolving piperacillin acid and tazobactam acid in a definite ratio in the presence of sodium ethyl hexanoate which is then crystallised under specific conditions to obtain the homogene...

Penicillanic acid 1 1-dioxide  and esters thereof such as Sulbactam Sodium are used as antibacterial agents and also enhance the effectiveness of several ß-lactam antibiotics against many ß-lactamase producing bacteria. A process for the production of crystal of Sulbactam Sodium is disclosed here involving reaction ...