A process for preparation of 4-fluoro- α -[2-methyl-l-oxopropyl]-Y-oxo-N-β- diphenylbenzene butane amide also known as a diketone intermediate of atorvastatin, completely devoid of impurities 3,4-difluoro- α -[2-methyl-l-oxopropyl]-y-oxo-n-β-diphenylbenzene butane amide; methyl, 2{-2[-(4-fluorophenyl)-2-oxo-l-phenyl...

The present disclosure relates to an efficient method for preparing 4-oxime-5`-(2- methylpropionyl) uridine compound in substantially pure form and high yield suitable for commercial scale; a novel intermediate N'-(1,2-dihydro-1-((2R,3R,4S,5R)-tetrahydro-3,4-dihydroxy-5-(hydroxymethyl) furan-2-yl)-2-oxopyrimidin-4...

The present invention application provides impurity-controlled and cost-effective process for the preparation of Rosuvastatin intermediate compound of formula (I) in high yields which is suitable for manufacturing in commercial scale. formula (I)

The present application provides an impurity controlled process for the preparation of 4,6-dichloro-2-(propylthio)pyrimidin-5-amine compound of formula (I), in high yields and purity, which is suitable for manufacturing in commercial scale.

The present application provides an improved process for the preparation of Bempedoic acid compound of formula I. formula (I)

The present invention relates to an improved process for the preparation of tert-butyl 5-hydroxy-3-oxohexanoate compound of formula (I) wherein: R1 is CN, halogen, or O-protecting group. (I) The tert-butyl 5-hydroxy-3-oxohexanoate compound of formula (I) is the key intermediate for the preparation of atorvastat...

The present invention relates to a continuous flow process for the preparation of tert-butyl 5-hydroxy-3-oxohexanoatecompound of formula (I) wherein: R1 is CN, halogen or O-protecting group. (I) The tert-butyl 5-hydroxy-3-oxohexanoatecompound of formula (I) is the key intermediate for the preparation of atorvas...

The present application provides an improved process for the preparation of chiral diol sulfones of formula (I) which are useful as potential intermediates for the preparation of Rosuvastatin in high yields and suitable for manufacturing in commercial scale.

The present invention provides a novel and cost effective process for the preparation of Sitagliptin intermediate (3-(trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride) which is suitable to manufacture in commercial scale. formula (I)

The present application provides an improved process for the preparation of chiral diol sulfones of formula (I) which are useful as potential intermediates for the preparation of Rosuvastatin in high yields and suitable for manufacturing in commercial scale. Formula (I)

The present invention relates to a process for the preparation of statin advanced intermediates by using Julia-Kocienski reaction between an aldehyde and a sulfone derivative in the presence of combination of solvents and a metal hydroxy base. The resulting derivatives are advanced intermediates for statin type comp...

The present invention provides an improved process for the preparation of Sitagliptin intermediate (3-(trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride) which is suitable to manufacture in commercial scale. formula (I)

The present invention application relates to cost effective and commercially viable process for the preparation Bempedoic acid compound of formula I. Formula I

The present invention provides improved process for the preparation of substantially pure 4-bromo-1-chloro-2-(4-ethoxybenzyl) benzene a dapagliflozin intermediate compound of formula (I) which is suitable to manufacture in commercial scale. Formula (I)

The present disclosure provides a novel process for the preparation of Bexagliflozin, (2s,3r,4r,5s,6r)-2-(4-chloro-3-(4-(2-cyclopropoxyethoxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol and its salts, solvates compound of formula (I) and its intermediates which is suitable to manufacture in comme...

The present invention provides improved process for the preparation of substantially pure (1R,2S)-2-(3,4-difluorophenyl)cyclopropan-1-amine hydrochloride - a ticagrelor intermediate compound of formula (I) which is suitable to manufacture in commercial scale. Formula (I)

The present invention provides improved process for the preparation of 3-aminopiperidine-2,6-dione hydrochloride a lenalidomide and pomalidomide intermediate compound of formula (I) which is suitable to manufacture in commercial scale.

The present invention provides a process for the preparation of (s)-3-(4-(5-bromo-2-chlorobenzyl)phenoxy)tetrahydrofuran a empagliflozin intermediate compound of formula (I) which is suitable to manufacture in commercial scale.

The present invention provides an improved process for the preparation of substantially pure 2-(((3aR,4S,6R,6aS)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol - a ticagrelor intermediate compound of formula (I) which is suitable to manufacture in commercial scale. ...

Provides an improved process for the preparation of Bexagliflozin, (2s,3r,4r,5s,6r)-2-(4-chloro-3-(4-(2-cyclopropoxyethoxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2h-pyran-3,4,5-triol and its salts, of compound of formula (I) and its intermediates which is suitable to manufacture in commercial scale. Formula (...

The present invention relates to a process for the preparation of(2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-(2-cyclopropoxyethoxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol compound of formula (I) which is suitable to manufacture in commercial scale. Formula (I)

The present invention provides a one-pot process for the preparation of substantially pure (1R,2R,3S,5R)-3-(7-(((1S,2R)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol - a ticagrelor compound of formula (I) which is suitable t...

provides a novel process for the preparation of (2s,3r,4r,5s,6r)-2-(4-chloro-3-(4-(2-cyclopropoxyethoxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2h-pyran-3,4,5-triol; Bexagliflozin and its salts, solvates of compound of formula (I) and its intermediates which is suitable to manufacture in commercial scale. Fo...