Disclosed herein is a process for the preparation of Darifenacin hydrobromide using novel intermediate of formula X, which is prepared by the reaction of compound of formula VIII with p-Toluene sulfonyl chloride in the presence of a phase transfer catalyst and alkali metal salts to give a compound of formula IX and ...
Disclosed herein is a process for the manufacture of Mirtazapine which comprises a) hydrolysis of 1 -(3-cyanopyridyl-2)-4-methyl-2-phenylpiperazine in alkaline conditions under reflux to give l-(3-carboxypyridyl-2)-4-methyl-2-phenylpiperazine; b) reduction of l-(3-carboxypyridyl-2)-4-methyl-2-phenylpiperazine using ...