Disclosed herein is improved, cost effective process for preparation of water soluble ferric carboxymaltose with reduced impurity suitable for preparation of medicament without involving further purification. Particularly, the present invention discloses the process of manufacturing ferric carboxymaltose obtained by...
Disclosed herein is a solvent free and cost effective process for preparation of pharmaceutical grade Ferric Citrate. The so obtained Ferric citrate is useful for the treatment of HyperPhosphatemia.
“IMPROVED AND COST EFFECTIVE PROCESS FOR PREPARING IRON-ISOMALTOSIDE”
ABSTRACT:
Disclosed herein is improved, cost effective process for preparation of water soluble Iron isomaltoside complex which is stable, has reduced toxicity useful in the treatment of iron deficiency anaemia.
The present invention discloses industrially viable and cost effective process for preparation of SucroFerric Oxyhydroxide with a particle size of upto 50 microns. The invention further discloses pharmaceutical compositions comprising SucroFerric Oxyhydroxide characterised by Bulk Density of about 0.9(g/cm3); partic...
The present invention provides a process for synthesis of solvent free water soluble
Ferric derisomaltose which is free of toxic impurities. The process includes use of in
situ preparation of modified dextran which is free of low molecular weight
carbohydrate and have molecular weight in range of 850 Dalton-1800 ...
Development and process of synthesis of better soluble Ferric carboxymaltose attaining desired molecular weight, PDI, high solubility, uniform distribution of the complex through an improved process with less contamination effects for treatment of iron deficiency with less anaphylactic shock. The advanced process o...
ABSTRACT
A PHARMACEUTICALLY ACCEPTABLE FERRIC CARBOXYMALTOSE AND PREPARATION THEREOF
The present invention relates to a pharmaceutical acceptable ferric carboxymaltose with better characterisation for bio-available iron and process for preparation thereof. The process comprises a controlled oxidation step to minim...
The present invention relates to a novel polymorphic form of Fe (III) maltol. The novel polymorph ‘S’ of Fe (III) maltol has high solubility, high stability, higher purity and better efficacy as compared to the existing polymorphic forms of ferric maltol. The present invention also provides an economical process of ...
The present invention relates to a pharmaceutical acceptable iron (III) coordination complex having high phosphate binding capacity prepared through a cost-effective and an organic solvent free route. The present invention provides a pharmaceutical composition of iron (III) coordination complex which not only releas...
The present invention relates to an eco-friendly process for the preparation of ferrous Ascorbate, a metal chelate of iron (Fe) in the ferrous state with ascorbic acid, using green chemistry principles. The process is free from harmful chemicals such as halides, sulfates, peroxides, and organic solvents. The process...
The present invention relates to a novel process for the preparation of Iron (III)-Polymaltose Complex (IPC), a widely used pharmaceutical agent for treating iron-deficiency anemia. The process involves the preparation of ferric hydroxide by three alternative methods:
(1) reaction of ferric chloride with sodium car...
The present invention provides a novel, one-pot, scalable process for synthesizing calcium gluconate in its monohydrate and anhydrous or essentially anhydrous forms. The process involves a two-step method: (1) hydrolysis of glucono-delta-lactone (GDL) in water to form gluconic acid under controlled conditions, and (...
The present invention discloses a novel liposomal ferric pyrophosphate composition and its manufacturing process, addressing critical challenges in iron supplementation. This invention utilizes liposome-coated liposomes to enhance iron delivery, achieving high encapsulation efficiency (>89%). The manufacturing proce...
Abstract
Title: Greener Synthetic Approach for producing white Calcium Ascorbate Dihydrate
The invention provides a greener, synthetic process for producing white calcium ascorbate dihydrate, a compound widely used in pharmaceuticals and nutraceuticals. Utilizing only water as a solvent and operating at temperatures...
Title: A Greener one-pot synthetic approach of white Zinc Ascorbate
The present invention relates to a novel, greener, one-pot process for synthesis of white zinc ascorbate in aqueous medium, free from organic solvents, acids, bases, or toxic intermediates. The process is scalable, energy-efficient, cost-effective,...
ABSTRACT:
Title: In-situ Greener Synthetic Approach of L-Ornithine L-Aspartate
The present invention addresses the challenge of synthesizing L-Ornithine L-Aspartate (LOLA) free from toxic impurities such as ammonium, chloride, and sulphate, common in conventional methods. The present invention provides an innovat...
ABSTRACT
Title: Green, Scalable Process for Preparation of Exclusive Unilamellar Liposomal Zinc by Means of Capped Technology
The present invention discloses a novel green, organic solvent-free, scalable method for preparing unilamellar liposomal zinc using water as the solvent, and maltodextrin as a capping agent ...