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2,3 Dihydrobenzo[1,4] Dioxin 2 Ylmethyl Derivatives As Alpha2 C Antagonists For Use In The Treatment Of Peripheric And Central Nervous Systeme Diseases
Abstract: Compounds of formula (I), wherein X, Z, R1-R4, and m are as defined in the claims, exhibit alpha2C antagonistic activity and are thus useful for the treatment of diseases and conditions of the peripheric system and the central nervous system (CNS).
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Notices, Deadlines & Correspondence
Notices, Deadlines & Correspondence
Patent Information
Application #
Filing Date
23 December 2009
Publication Number
21/2010
Publication Type
INA
Invention Field
CHEMICAL
Status
Email
Parent Application
Patent Number
Legal Status
Grant Date
2016-03-08
Renewal Date
Applicants
ORION CORPORATION
ORIONINTIE 1, FI-02200 ESPOO, FINLAND
Inventors
1. DIN BELLE, DAVID
LOUHENTIE 13 A 5, FIN-02130 ESPOO, FINLAND
2. HOLM, PATRIK
NILSBYNKAARI 77, 21630 LIELAHTI TL FINLAND
3. KARLJALAINEN, ARTO
ALBERGANESPLANADI 11 A, FI-02600 ESPOO FINLAND
4. TOLVANEN, ARTO
TONTUNMAENTIE 25 B, FIN-02200 ESPOO FINLAND
5. WOHLFAHRT, GERD
VATTUNIEMENKATU 14 C 35, FI-00210 HELSINKI, FINLAND
6. RUMMAKKO, PETTERI
HAAGANKAARI 12, FIN-02580 SIUNTIO FINLAND
Specification
(54) Title: 2,3-DIHYDROBENZ0[l, 4] D[OXIN-2-YLMETHYL DERIVATIVES AS ALPHA2C ANTAGONISTS FOR USE IN
THE TREATMENT OF PERIPHERIC AND CENTRAL NERVOUS SYSTEME DISEASES
(57) Abstract: Compounds of formula (I), wherein
X, Z, R1-R4, and in are as defined in the claims, exhibit
alpha2C antagonistic activity and are thus useful
for the treatment of diseases and conditions of
the peripheric system and the central nervous system (CNS).
Documents
Application Documents
| # | Name | Date |
|---|---|---|
| 1 | 4467-KOLNP-2009-FORM-27 [18-09-2024(online)].pdf | 2024-09-18 |
| 1 | abstract-4467-kolnp-2009.jpg | 2011-10-08 |
| 2 | 4467-KOLNP-2009-RELEVANT DOCUMENTS [10-07-2023(online)].pdf | 2023-07-10 |
| 2 | 4467-kolnp-2009-specification.pdf | 2011-10-08 |
| 3 | 4467-KOLNP-2009-RELEVANT DOCUMENTS [21-09-2022(online)].pdf | 2022-09-21 |
| 3 | 4467-kolnp-2009-pct request form.pdf | 2011-10-08 |
| 4 | 4467-KOLNP-2009-RELEVANT DOCUMENTS [07-09-2021(online)].pdf | 2021-09-07 |
| 4 | 4467-kolnp-2009-pct priority document notification.pdf | 2011-10-08 |
| 5 | 4467-KOLNP-2009-PA.pdf | 2011-10-08 |
| 5 | 4467-KOLNP-2009-FORM-26 [09-02-2021(online)].pdf | 2021-02-09 |
| 6 | 4467-KOLNP-2009-RELEVANT DOCUMENTS [29-02-2020(online)].pdf | 2020-02-29 |
| 6 | 4467-kolnp-2009-international publication.pdf | 2011-10-08 |
| 7 | 4467-KOLNP-2009-RELEVANT DOCUMENTS [05-03-2019(online)].pdf | 2019-03-05 |
| 7 | 4467-KOLNP-2009-FORM-18.pdf | 2011-10-08 |
| 8 | 4467-KOLNP-2009-RELEVANT DOCUMENTS [08-03-2018(online)].pdf | 2018-03-08 |
| 8 | 4467-kolnp-2009-form 5.pdf | 2011-10-08 |
| 9 | 4467-KOLNP-2009-CANCELLED PAGES.pdf | 2017-09-05 |
| 9 | 4467-KOLNP-2009-FORM 5-1.1.pdf | 2011-10-08 |
| 10 | 4467-kolnp-2009-form 3.pdf | 2011-10-08 |
| 10 | Form 27 [08-02-2017(online)].pdf | 2017-02-08 |
| 11 | 4467-KOLNP-2009-FORM 3.1.1.pdf | 2011-10-08 |
| 11 | 4467-KOLNP-2009_EXAMREPORT.pdf | 2016-06-30 |
| 12 | 4467-KOLNP-2009-ASSIGNMENT.pdf | 2016-04-29 |
| 12 | 4467-kolnp-2009-form 2.pdf | 2011-10-08 |
| 13 | 4467-kolnp-2009-correspondence.pdf | 2016-04-29 |
| 13 | 4467-kolnp-2009-form 1.pdf | 2011-10-08 |
| 14 | 4467-KOLNP-2009-EXAMINATION REPORT.pdf | 2016-04-29 |
| 14 | 4467-KOLNP-2009-FORM 1-1.1.pdf | 2011-10-08 |
| 15 | 4467-kolnp-2009-description (complete).pdf | 2011-10-08 |
| 15 | 4467-KOLNP-2009-FORM 13.pdf | 2016-04-29 |
| 16 | 4467-KOLNP-2009-CORRESPONDENCE-1.3.pdf | 2011-10-08 |
| 16 | 4467-KOLNP-2009-FORM 18.pdf | 2016-04-29 |
| 17 | 4467-KOLNP-2009-GPA.pdf | 2016-04-29 |
| 17 | 4467-KOLNP-2009-CORRESPONDENCE-1.1.pdf | 2011-10-08 |
| 18 | 4467-KOLNP-2009-CORRESPONDENCE 1.2.pdf | 2011-10-08 |
| 18 | 4467-KOLNP-2009-GRANTED-ABSTRACT.pdf | 2016-04-29 |
| 19 | 4467-kolnp-2009-claims.pdf | 2011-10-08 |
| 19 | 4467-KOLNP-2009-GRANTED-CLAIMS.pdf | 2016-04-29 |
| 20 | 4467-KOLNP-2009-ASSIGNMENT 1.1.pdf | 2011-10-08 |
| 20 | 4467-KOLNP-2009-GRANTED-DESCRIPTION (COMPLETE).pdf | 2016-04-29 |
| 21 | 4467-kolnp-2009-abstract.pdf | 2011-10-08 |
| 21 | 4467-KOLNP-2009-GRANTED-FORM 1.pdf | 2016-04-29 |
| 22 | 4467-KOLNP-2009-(22-12-2015)-PETITION UNDER RULE 137.pdf | 2015-12-22 |
| 22 | 4467-KOLNP-2009-GRANTED-FORM 2.pdf | 2016-04-29 |
| 23 | 4467-KOLNP-2009-(22-12-2015)-OTHERS.pdf | 2015-12-22 |
| 23 | 4467-KOLNP-2009-GRANTED-FORM 3.pdf | 2016-04-29 |
| 24 | 4467-KOLNP-2009-GRANTED-FORM 5.pdf | 2016-04-29 |
| 24 | 4467-KOLNP-2009-(22-12-2015)-CORRESPONDENCE.pdf | 2015-12-22 |
| 25 | 4467-KOLNP-2009-(22-12-2015)-CLAIMS.pdf | 2015-12-22 |
| 25 | 4467-KOLNP-2009-GRANTED-LETTER PATENT.pdf | 2016-04-29 |
| 26 | 4467-KOLNP-2009-(22-12-2015)-ANNEXURE TO FORM 3.pdf | 2015-12-22 |
| 26 | 4467-KOLNP-2009-GRANTED-SPECIFICATION-COMPLETE.pdf | 2016-04-29 |
| 27 | 4467-KOLNP-2009-INTERNATIONAL SEARCH REPORT & OTHERS.pdf | 2016-04-29 |
| 27 | 4467-KOLNP-2009-REPLY TO EXAMINATION REPORT.pdf | 2016-04-29 |
| 28 | 4467-KOLNP-2009-OTHERS.pdf | 2016-04-29 |
| 28 | 4467-KOLNP-2009-PETITION UNDER RULE 137.pdf | 2016-04-29 |
| 29 | 4467-KOLNP-2009-OTHERS.pdf | 2016-04-29 |
| 29 | 4467-KOLNP-2009-PETITION UNDER RULE 137.pdf | 2016-04-29 |
| 30 | 4467-KOLNP-2009-INTERNATIONAL SEARCH REPORT & OTHERS.pdf | 2016-04-29 |
| 30 | 4467-KOLNP-2009-REPLY TO EXAMINATION REPORT.pdf | 2016-04-29 |
| 31 | 4467-KOLNP-2009-(22-12-2015)-ANNEXURE TO FORM 3.pdf | 2015-12-22 |
| 31 | 4467-KOLNP-2009-GRANTED-SPECIFICATION-COMPLETE.pdf | 2016-04-29 |
| 32 | 4467-KOLNP-2009-(22-12-2015)-CLAIMS.pdf | 2015-12-22 |
| 32 | 4467-KOLNP-2009-GRANTED-LETTER PATENT.pdf | 2016-04-29 |
| 33 | 4467-KOLNP-2009-(22-12-2015)-CORRESPONDENCE.pdf | 2015-12-22 |
| 33 | 4467-KOLNP-2009-GRANTED-FORM 5.pdf | 2016-04-29 |
| 34 | 4467-KOLNP-2009-(22-12-2015)-OTHERS.pdf | 2015-12-22 |
| 34 | 4467-KOLNP-2009-GRANTED-FORM 3.pdf | 2016-04-29 |
| 35 | 4467-KOLNP-2009-(22-12-2015)-PETITION UNDER RULE 137.pdf | 2015-12-22 |
| 35 | 4467-KOLNP-2009-GRANTED-FORM 2.pdf | 2016-04-29 |
| 36 | 4467-KOLNP-2009-GRANTED-FORM 1.pdf | 2016-04-29 |
| 36 | 4467-kolnp-2009-abstract.pdf | 2011-10-08 |
| 37 | 4467-KOLNP-2009-ASSIGNMENT 1.1.pdf | 2011-10-08 |
| 37 | 4467-KOLNP-2009-GRANTED-DESCRIPTION (COMPLETE).pdf | 2016-04-29 |
| 38 | 4467-kolnp-2009-claims.pdf | 2011-10-08 |
| 38 | 4467-KOLNP-2009-GRANTED-CLAIMS.pdf | 2016-04-29 |
| 39 | 4467-KOLNP-2009-CORRESPONDENCE 1.2.pdf | 2011-10-08 |
| 39 | 4467-KOLNP-2009-GRANTED-ABSTRACT.pdf | 2016-04-29 |
| 40 | 4467-KOLNP-2009-CORRESPONDENCE-1.1.pdf | 2011-10-08 |
| 40 | 4467-KOLNP-2009-GPA.pdf | 2016-04-29 |
| 41 | 4467-KOLNP-2009-CORRESPONDENCE-1.3.pdf | 2011-10-08 |
| 41 | 4467-KOLNP-2009-FORM 18.pdf | 2016-04-29 |
| 42 | 4467-kolnp-2009-description (complete).pdf | 2011-10-08 |
| 42 | 4467-KOLNP-2009-FORM 13.pdf | 2016-04-29 |
| 43 | 4467-KOLNP-2009-EXAMINATION REPORT.pdf | 2016-04-29 |
| 43 | 4467-KOLNP-2009-FORM 1-1.1.pdf | 2011-10-08 |
| 44 | 4467-kolnp-2009-correspondence.pdf | 2016-04-29 |
| 44 | 4467-kolnp-2009-form 1.pdf | 2011-10-08 |
| 45 | 4467-KOLNP-2009-ASSIGNMENT.pdf | 2016-04-29 |
| 45 | 4467-kolnp-2009-form 2.pdf | 2011-10-08 |
| 46 | 4467-KOLNP-2009_EXAMREPORT.pdf | 2016-06-30 |
| 46 | 4467-KOLNP-2009-FORM 3.1.1.pdf | 2011-10-08 |
| 47 | 4467-kolnp-2009-form 3.pdf | 2011-10-08 |
| 47 | Form 27 [08-02-2017(online)].pdf | 2017-02-08 |
| 48 | 4467-KOLNP-2009-CANCELLED PAGES.pdf | 2017-09-05 |
| 48 | 4467-KOLNP-2009-FORM 5-1.1.pdf | 2011-10-08 |
| 49 | 4467-kolnp-2009-form 5.pdf | 2011-10-08 |
| 49 | 4467-KOLNP-2009-RELEVANT DOCUMENTS [08-03-2018(online)].pdf | 2018-03-08 |
| 50 | 4467-KOLNP-2009-FORM-18.pdf | 2011-10-08 |
| 50 | 4467-KOLNP-2009-RELEVANT DOCUMENTS [05-03-2019(online)].pdf | 2019-03-05 |
| 51 | 4467-KOLNP-2009-RELEVANT DOCUMENTS [29-02-2020(online)].pdf | 2020-02-29 |
| 51 | 4467-kolnp-2009-international publication.pdf | 2011-10-08 |
| 52 | 4467-KOLNP-2009-PA.pdf | 2011-10-08 |
| 52 | 4467-KOLNP-2009-FORM-26 [09-02-2021(online)].pdf | 2021-02-09 |
| 53 | 4467-KOLNP-2009-RELEVANT DOCUMENTS [07-09-2021(online)].pdf | 2021-09-07 |
| 53 | 4467-kolnp-2009-pct priority document notification.pdf | 2011-10-08 |
| 54 | 4467-KOLNP-2009-RELEVANT DOCUMENTS [21-09-2022(online)].pdf | 2022-09-21 |
| 54 | 4467-kolnp-2009-pct request form.pdf | 2011-10-08 |
| 55 | 4467-KOLNP-2009-RELEVANT DOCUMENTS [10-07-2023(online)].pdf | 2023-07-10 |
| 55 | 4467-kolnp-2009-specification.pdf | 2011-10-08 |
| 56 | 4467-KOLNP-2009-FORM-27 [18-09-2024(online)].pdf | 2024-09-18 |
| 56 | abstract-4467-kolnp-2009.jpg | 2011-10-08 |