DESC:FIELD OF THE INVENTION
The present invention relates to a synergistic fungicidal compositions comprising first fungicide A, Prothioconazole and second fungicide B, selected from Cyazofamid, Cymoxanil or Dimethomorph; and third fungicide C, selected from Azoxystrobin, Fenaminstrobin, Picoxystrobin, Pyraclostrobin, Pyraoxystrobin or Trifloxystrobin; formulation thereof and to a method of controlling undesired fungi-pests in economically important crops.
BACKGROUND OF THE INVENTION
Diseases caused by fungi are a common occurrence on plants, often having a significant economic impact on yield and quality, thus managing fungal diseases is an essential component of production for most crops. Fungi often spoil (render unusable) crops in fields, stored fruits, vegetables, tubers, and seeds. Attempts have been made to control the fungal diseases on plants by using single or mixed fungicide active ingredients. Practical agricultural experience has shown that the repeated and exclusive application of an individual active compound in the control of harmful fungi leads in many cases to a rapid selection of those fungus strains which have developed natural or adapted resistance against the active compound in question. Effective control of these fungi with the active compound in question is very difficult in such cases.
To reduce the risk of the selection of resistant fungus strains, mixtures of different active compounds are nowadays conventionally employed for controlling harmful fungi. By combining active compounds having different mechanisms of action, it is possible to ensure successful control of fungi over a relatively long period of time.
However to minimize the cost of efficient integrated fungi-pest management programs, easy availability of fungicides and to delay the fungi-pest resistance it is necessary to develop a novel fungicidal compositions showing a broader scope of activity and a synergistic effect in order to avoid or to control the development of resistant strains to the active ingredients or to the mixtures of known active ingredients used by the farmer while minimising the doses of chemical products sprayed in the agriculture fields and reducing the cost of the treatment. A need also exists for synergistic compositions which shall be physico-chemically compatible formulations in the form of storage stable, safely packed and ready to use formulation.
As a solution to the above mentioned problems, the inventors of the present invention surprisingly found that compositions comprising first fungicide A, Prothioconazole and second fungicide B, selected from Cyazofamid, Cymoxanil or Dimethomorph; and third fungicide C, selected from Azoxystrobin, Fenaminstrobin, Picoxystrobin, Pyraclostrobin, Pyraoxystrobin or Trifloxystrobin provides effective control of a wide spectrum of fungal diseases.
SUMMARY OF THE INVENTION
Accordingly, the present invention provides a compositions comprising first fungicide A, Prothioconazole and second fungicide B, selected from Cyazofamid, Cymoxanil or Dimethomorph; and third fungicide C, selected from Azoxystrobin, Fenaminstrobin, Picoxystrobin, Pyraclostrobin, Pyraoxystrobin or Trifloxystrobin and agriculturally acceptable excipient(s).
In one aspect, the compositions of the present invention comprises first fungicide Prothioconazole in an amount in the range from 5 to 30 % w/w; and second fungicides selected from Cyazofamid in an amount in the range from 0.1 to 10 % w/w or Cymoxanil in an amount in the range from 2 to 13 % w/w or Dimethomorph in an amount in the range from 15 to 35 % w/w; and third fungicides selected from Azoxystrobin in an amount in the range from 2 to 15% w/w or Fenaminstrobin in an amount in the range from 2 to 15% w/w or Picoxystrobin in an amount in the range from 4 to 24% w/w or Pyraclostrobin in an amount in the range from 2 to 12% w/w or Pyraoxystrobin in an amount in the range from 1 to 12% w/w or Trifloxystrobin in an amount in the range from 0.1 to 5% w/w and agriculturally acceptable excipient(s).

In one other aspect, the compositions of the present invention comprises first fungicide Prothioconazole in an amount in the range from 10 to 25 % w/w; and second fungicides selected from Cyazofamid in an amount in the range from 2 to 7% w/w or Cymoxanil in an amount the range from 5 to 10 % w/w or Dimethomorph in an amount in the range from 20 to 30 % w/w; and third fungicides selected from Azoxystrobin in an amount in the range from 5 to 10% w/w or Fenaminstrobin in an amount in the range from 5 to 10% w/w or Picoxystrobin in an amount in the range from 10 to 18% w/w or Pyraclostrobin in an amount in the range from 6 to 8% w/w or Pyraoxystrobin in an amount in the range from 4.5 to 8% w/w or Trifloxystrobin in an amount in the range from 1 to 3% w/w.

In another aspect, the compositions of the present invention is selected from a group comprising:
Prothioconazole is present in an amount in the range from 10 to 25% w/w and Cyazofamid is present in an amount in the range from 2 to 7% w/w and Azoxystrobin is present in an amount in the range from 5 to 10% w/w or Fenaminstrobin is present in an amount in the range from 5 to 10% w/w or Picoxystrobin is present in an amount in the range from 10 to 18% w/w or Pyraclostrobin is present in an amount in the range from 6 to 8% w/w or Pyraoxystrobin is present in an amount in the range from 4.5 to 8% w/w or Trifloxystrobin is present in an amount in the range from 1 to 3% w/w and agriculturally acceptable excipients;
Prothioconazole is present in an amount in the range from 10 to 25% w/w and Cymoxanil is present in an amount in the range from 5 to 10% w/w and Azoxystrobin is present in an amount in the range from 5 to 10% w/w or Fenaminstrobin is present in an amount in the range from 5 to 10% w/w or Picoxystrobin is present in an amount in the range from 10 to 18% w/w or Pyraclostrobin is present in an amount in the range from 6 to 8% w/w or Pyraoxystrobin is present in an amount in the range from 4.5 to 8% w/w or Trifloxystrobin is present in an amount in the range from 1 to 3% w/w and agriculturally acceptable excipients;
Prothioconazole is present in an amount in the range from 15 to 25% w/w and Dimethomorph is present in an amount in the range from 20 to 30% w/w and Fenaminstrobin is present in an amount in the range from 7.5 to 10% w/w or Pyraoxystrobin is present in an amount in the range from 5 to 8% w/w and agriculturally acceptable excipients;
In another aspect, the present invention provides a process of preparation of the compositions comprising first fungicide A, Prothioconazole and second fungicide B, selected from Cyazofamid, Cymoxanil or Dimethomorph; and third fungicide C, selected from Azoxystrobin, Fenaminstrobin, Picoxystrobin, Pyraclostrobin, Pyraoxystrobin or Trifloxystrobin and agriculturally acceptable excipient(s).
In an aspect, the compositions of the present invention are formulated as Suspension concentrate (SC), Dispersible concentrate (DC), Dustable powder (DP), Powder for dry seed treatment (DS), Flowable concentrate for seed treatment (FS), Oil-dispersion (OD), Water dispersible granules (WDG/WG), Wettable powder (WP), Water dispersible powder for slurry seed treatment (WS), Water dispersible tablet (WT), preferably Suspension concentrate (SC), and Wettable powder (WP).
In another aspect, the compositions of the present invention comprises one or more agriculturally acceptable excipient selected from the group comprising of dispersing agent(s), wetting agent(s), dispersing cum wetting agent(s), disintegrating agent(s), defoaming agent(s) / defoamer(s) / antifoaming agent(s) / antifoamer(s), biocide(s)/preservative(s), viscosity modifier(s)/ rheology modifier(s)/ thickener(s), anti-freeze agent(s), pH modifier(s), pH stabilizer(s), anti-caking agent(s), solvent(s), filler(s), diluent(s) or a combination thereof and other excipients as will be required in a particular type of formulation.
In another aspect, the compositions of the present invention comprises;
the dispersing agent, is selected from the group comprising polymethyl methacrylate-polyethylene glycol graft copolymer, acrylate copolymer liquid dispersant, condensed methyl naphthalene sulfonate sodium salt, acrylate copolymer grafted with PEG, polyoxy ethylene alkyl aryl phosphate amine salt, poly-carboxylate dispersant, sodium polycarboxylate, modified styrene acrylic polymeric dispersant, sodium lignosulphonate, sodium salt of naphthalene sulfonate condensate or a combination thereof, and present in an amount in the range from 0.1 to 20% w/w;
the wetting agent, is selected from the group comprising polyoxyethylene alkyl ether, sodium alkyl naphthalene sulfonate blend, Adsee 2610 (non-ionic proprietary blend of supplier), polyalkylene oxide block copolymer, ethoxylated tristyrylphenol, sodium isopropyl naphthalene sulfonate, sodium butyl naphthalene sulfonate, sodium dioctylsulphosuccinate, or a combination thereof and present in an amount in the range from 0.1-10% w/w;
the dispersing cum wetting agent, is selected from the group comprising proprietary blend of phosphate ester and sodium naphthalene sulphate formaldehyde condensate, Jeemox SCR (proprietary blend of supplier), modified styrene acrylic polymeric dispersant or a combination thereof and present in an amount in the range from 2-10% w/w;
the anti-freeze agent, is selected from the group comprising glycerol, propylene glycol, diethylene glycol, monoethylene glycol or a combination thereof and present in an amount in the range from 1 to 10% w/w;
the antifoamer/defoamer, is selected from the group comprising polydimethylsiloxane antifoam emulsion, silicon emulsion, polysiloxane emulsion or a combination thereof and present in an amount in the range from 0.01 to 2% w/w;
the biocide/preservative, is selected from the group comprising 20% aqueous dipropylene glycol solution of 1, 2-benzisothiazolin-3-one, formaldehyde, isothiazolinone or a combination thereof and present in an amount in the range from 0.01 to 1% w/w;
the thickener, is selected from the group comprising xanthan gum, welan gum, guar gum, polyvinyl alcohol, carboxymethylcellulose, polyvinylpyrrolidone, carboxyvinyl polymer, acrylic polymer, starch derivative, polysaccharide, high purity silica, white carbon or a combination thereof and present in an amount in the range from 0.1-0.5% w/w;
the pH stabilizer is citric acid and present in an amount in the range from 0.1 to 1.0% w/w;

the anticaking agent is selected from the group comprising precipitated silica, organic bentonite, polyolefin particles, fumed silica or a combination thereof, and present in an amount in the range from 1 to 3% w/w;
the filler, is selected from the group comprising, silica, precipitated silica, sodium bicarbonate, china clay, lactose, bentonite clay, kaolin, diatomaceous earth or a combination thereof and present in an amount quantity sufficient; and
the diluent is demineralised water and present in an amount quantity sufficient.
DETAILED DESCRIPTION OF THE INVENTION
The definitions provided herein for the terminologies used in the present disclosure are for illustrative purpose only and in no manner limit the scope of the present invention disclosed in the present disclosure.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by a person of ordinary skill in the art to which the invention pertains. Although other methods and materials similar, or equivalent, to those described herein can be used in the practice of the present invention, the preferred materials and methods are described herein.
It is to be noted that, as used in the specification and the appended claims, the singular forms "a", "an" and "the" include plural referents unless the context clearly dictates otherwise. Thus, for example, reference to a composition containing “a compound” includes a mixture of two or more compounds. It should also be noted that the term “or” is generally employed in its sense including “and/or” unless the content clearly dictates otherwise.
As used herein, the terms "comprises", "comprising", "includes", "including", “has”, “having”, “contains”, “containing”, “characterized by” or any other variation thereof, are intended to cover a non-exclusive inclusion, subject to any limitation explicitly indicated. For example, a composition, mixture, process or a method that comprises a list of elements is not necessarily limited to only those elements but may include other elements not expressly listed or inherent to such composition, mixture, process or method.
The transitional phrase “consisting of” excludes any element, step or ingredient not specified. If in the claim, such would close the claim to the inclusion of materials other than those recited except for impurities ordinarily associated therewith. When the phrase “consisting of” appears in a clause of the body of a claim, rather than immediately following the preamble, it limits only the element set forth in that clause; other elements are not excluded from the claim as a whole.
As used herein, the terms “composition” or “compositions” or "formulation" or "formulations" can be used interchangeably, unless stated otherwise, is meant to encompass, and are not limited to, compositions or formulations containing the combination of first fungicide A, Prothioconazole and second fungicide B, selected from Cyazofamid, Cymoxanil or Dimethomorph; and third fungicide C, selected from Azoxystrobin, Fenaminstrobin, Picoxystrobin, Pyraclostrobin, Pyraoxystrobin or Trifloxystrobin.
As used herein, the term “agriculturally acceptable excipient (s)” refers to inert substances and are auxiliary substances added to the processing or use of fungicide preparations and used to improve the physical and chemical properties of formulations. The auxiliaries themselves are essentially free of biological activity, but can affect the control effect.
The expression of various quantities in terms of “% w/w” or “%” means the percentage by weight, relative to the weight of the total solute on or composition unless otherwise specified.
The term “active ingredient” (a.i.) or “active agent” used herein refers to that component of the composition responsible for control of fungi-pests in crops of useful plants.
As used herein, the term "effective amount" means the amount of the active substances in the compositions to achieve an observable effect on death, retardation, prevention, and removal, destruction, or otherwise diminishing the occurrence and activity of the target fungi-pests in an amount not significantly toxic to the crops being treated. An effective amount of the compositions will also vary according to the prevailing conditions such as desired fungicidal effect and duration, weather, target fungi-pests and species, target crops, locus, mode of application, and the like.
As used herein, the term “fungicides”, refers to any chemical substance used to destroy/kill, inhibit or otherwise adversely affect the fungi-pests.
As used herein, the term “Prothioconazole” encompasses prothioconazole or its agrochemically acceptable salt(s), derivative(s), polymorph(s) or any other modified form of prothioconazole belongs to the class of triazolinthione fungicides. It acts as a sterol biosynthesis inhibitor. It is used to control Psuedocercosporella herpotrichoides, Fusarium spp., Microdochium nivale, Septoria tritici, Leptosphaeria nodorum, Pyrenophora spp., Rhynchosporium secalis, Puccinia spp. and Blumeria graminis, in wheat, barley and other crops by foliar application and control of Ustilago spp., Tilletia spp., Fusarium spp., and Microdochium nivale as a seed treatment.
As used herein, the term “Cyazofamid” encompasses cyazofamid or its agrochemically acceptable salt(s), derivative(s), polymorph(s) or any other modified form of cyazofamid and belongs to the class of cyanimidazole fungicides. It is used mainly for controlling Oomycete and Plasmodiophora diseases in potatoes, tomatoes, peppers and other vegetables and downy mildew in grapes, cucurbits, melons and other crops.
As used herein, the term “Cymoxanil” encompasses cymoxanil or its agrochemically acceptable salt(s), derivative(s), polymorph(s) or any other modified form of cymoxanil and belongs to the class of cyanoacetaamide oxime fungicides. It is used mainly for controlling Peronospora, Phytophthora and Plasmopara spp. in crops such as vines, hops, potatoes, tomatoes, curcurbits and lettuce.
As used herein, the term “Dimethomorph” encompasses dimethomorph or its agrochemically acceptable salt(s), derivative(s), polymorph(s) or any other modified form of dimethomorph and belongs to the class of cinnamamide fungicides. It acts by inhibition of phospholipid biosynthesis and cell wall synthesis. It is used to control of Oomycetes, especially Peronosporaceae and Phytophthora spp. in vines, potatoes, tomatoes, and other crops.
Strobilurin class of fungicides such as Azoxystrobin, Fenaminstrobin, Picoxystrobin, Pyraclostrobin, Pyraoxystrobin, Trifloxystrobin etc are widely used for controlling fungus diseases and are a part of the larger group of QoI (quinone outside inhibition) and acts as a Complex III or MET III electron transport inhibition.
As used herein, the term “Azoxystrobin” encompasses azoxystrobin or its agrochemically acceptable salt(s), derivative(s), polymorph(s) or any other modified form of azoxystrobin and belongs to the class of methoxyacrylate fungicides. It has the broadest spectrum of any antifungal treatment and effective against all four major groups of fungi – the Ascomycota, Deuteromycota, Basidiomycota and the Oomycota.
As used herein, the term “Fenaminstrobin” encompasses fenaminstrobin or its agrochemically acceptable salt(s), derivative(s), polymorph(s) or any other modified form of fenaminstrobin and belongs to class of oximinoacetamide fungicides and works as a broad-spectrum fungicide.
As used herein, the term “Picoxystrobin” encompasses picoxystrobin or its agrochemically acceptable salt(s), derivative(s), polymorph(s) or any other modified form of picoxystrobin and belongs to the class of methoxyacrylate fungicides. It is a preventive and curative fungicide and uses on canola, cereals grains, dried peas, corn and soybeans.
As used herein, the term “Pyraclostrobin” encompasses pyraclostrobin or its agrochemically acceptable salt(s), derivative(s), polymorph(s) or any other modified form of pyraclostrobin and belongs to the class of methoxycarbamate fungicides. It is a fungicide with protectant, curative and translaminar properties. It is used to control plant pathogens in cereals, peanuts, soybeans, grapes, potatoes, tomatoes, vegetables, banana, citrus, turf.
As used herein, the term “Pyraoxystrobin” encompasses pyraoxystrobin or its agrochemically acceptable salt(s), derivative(s), isomer(s), polymorph(s) or any other modified form of pyraoxystrobin and belongs to the class of methoxyacrylate fungicides. It is a broad spectrum fungicide used to control a variety of diseases like downey mildew, powdery mildew, Botrytis cinerea, Bipolaris oryzae, Alternmaria solani etc. in rice, vegetables, tomatoes and tea.
As used herein, the term “Trifloxystrobin” encompasses trifloxystrobin or its agrochemically acceptable salt(s), derivative(s), polymorph(s) or any other modified form of Trifloxystrobin and belongs to class of oximinoacetate fungicides. It used as broad spectrum fungicide with preventative and curative action in cereals, soybeans, maize, rice, cotton, peanuts, sugar beet, sunflower, fruit and ornamental, turf and many vegetables.
In an embodiment, the present invention provides a compositions comprising first fungicide A, Prothioconazole and second fungicide B, selected from Cyazofamid, Cymoxanil or Dimethomorph; and third fungicide C, selected from Azoxystrobin, Fenaminstrobin, Picoxystrobin, Pyraclostrobin, Pyraoxystrobin or Trifloxystrobin and agriculturally acceptable excipient(s).
In an embodiment, the present invention provides a compositions comprises first fungicide Prothioconazole in an amount in the range from 5 to 30 % w/w; and second fungicides selected from Cyazofamid in an amount in the range from 0.1 to 10 % w/w or Cymoxanil in an amount in the range from 2 to 13 % w/w or Dimethomorph in an amount in the range from 15 to 35 % w/w; and third fungicides selected from Azoxystrobin in an amount in the range from 2 to 15% w/w or Fenaminstrobin in an amount in the range from 2 to 15% w/w or Picoxystrobin in an amount in the range from 4 to 24% w/w or Pyraclostrobin in an amount in the range from 2 to 12% w/w or Pyraoxystrobin in an amount in the range from 1 to 12% w/w or Trifloxystrobin in an amount in the range from 0.1 to 5% w/w and agriculturally acceptable excipient(s).
In an embodiment, the compositions of the present invention comprises first fungicide Prothioconazole in an amount in the range from 10 to 25 % w/w; and second fungicides selected from Cyazofamid in an amount in the range from 2 to 7% w/w or Cymoxanil in an amount the range from 5 to 10 % w/w or Dimethomorph in an amount in the range from 20 to 30 % w/w; and third fungicides selected from Azoxystrobin in an amount in the range from 5 to 10% w/w or Fenaminstrobin in an amount in the range from 5 to 10% w/w or Picoxystrobin in an amount in the range from 10 to 18% w/w or Pyraclostrobin in an amount in the range from 6 to 8% w/w or Pyraoxystrobin in an amount in the range from 4.5 to 8% w/w or Trifloxystrobin in an amount in the range from 1 to 3% w/w and agriculturally acceptable excipient(s).
In an embodiment, the compositions of the present invention is selected from a group comprising:
Prothioconazole is present in an amount in the range from 10 to 25% w/w and Cyazofamid is present in an amount in the range from 2 to 7% w/w and Azoxystrobin is present in an amount in the range from 5 to 10% w/w or Fenaminstrobin is present in an amount in the range from 5 to 10% w/w or Picoxystrobin is present in an amount in the range from 10 to 18% w/w or Pyraclostrobin is present in an amount in the range from 6 to 8% w/w or Pyraoxystrobin is present in an amount in the range from 4.5 to 8% w/w or Trifloxystrobin is present in an amount in the range from 1 to 3% w/w and agriculturally acceptable excipients;
Prothioconazole is present in an amount in the range from 10 to 25% w/w and Cymoxanil is present in an amount in the range from 5 to 10% w/w and Azoxystrobin is present in an amount in the range from 5 to 10% w/w or Fenaminstrobin is present in an amount in the range from 5 to 10% w/w or Picoxystrobin is present in an amount in the range from 10 to 18% w/w or Pyraclostrobin is present in an amount in the range from 6 to 8% w/w or Pyraoxystrobin is present in an amount in the range from 4.5 to 8% w/w or Trifloxystrobin is present in an amount in the range from 1 to 3% w/w and agriculturally acceptable excipients;
Prothioconazole is present in an amount in the range from 15 to 25% w/w and Dimethomorph is present in an amount in the range from 20 to 30% w/w and Fenaminstrobin is present in an amount in the range from 7.5 to 10% w/w or Pyraoxystrobin is present in an amount in the range from 5 to 8% w/w and agriculturally acceptable excipients;
In an embodiment, the compositions of the present invention is selected from a group comprising:
Prothioconazole is present in an amount in the range from 10 to 20% w/w and Cyazofamid is present in an amount in the range from 2.5 to 6.0% w/w and Azoxystrobin is present in an amount in the range from 6 to 10% w/w and agriculturally acceptable excipients;
Prothioconazole is present in an amount in the range from 15 to 20% w/w and Cyazofamid is present in an amount in the range from 2.0 to 6.0% w/w and Fenaminstrobin is present in an amount in the range from 5 to 9% w/w and agriculturally acceptable excipients;
Prothioconazole is present in an amount in the range from 12 to 20% w/w and Cyazofamid is present in an amount in the range from 2.5 to 6.5% w/w and Picoxystrobin is present in an amount in the range from 10 to 15% w/w and agriculturally acceptable excipients;
Prothioconazole is present in an amount in the range from 12 to 20% w/w and Cyazofamid is present in an amount in the range from 2 to 6% w/w and Pyraclostrobin is present in an amount in the range from 6 to 8% w/w and agriculturally acceptable excipients;
Prothioconazole is present in an amount in the range from 15 to 25% w/w and Cyazofamid is present in an amount in the range from 2.5 to 6.5% w/w and Pyraoxystrobin is present in an amount in the range from 4.5 to 8% w/w and agriculturally acceptable excipients;
Prothioconazole is present in an amount in the range from 15 to 25% w/w and Cyazofamid is present in an amount in the range from 3 to 7% w/w and Trifloxystrobin is present in an amount in the range from 1 to 3% w/w and agriculturally acceptable excipients;
Prothioconazole is present in an amount in the range from 10 to 20% w/w and Cymoxanil is present in an amount in the range from 5 to 8% w/w and Azoxystrobin is present in an amount in the range from 5 to 10% w/w and agriculturally acceptable excipients;
Prothioconazole is present in an amount in the range from 15 to 20% w/w and Cymoxanil is present in an amount in the range from 5 to 8% w/w and Fenaminstrobin is present in an amount in the range from 5 to 9% w/w and agriculturally acceptable excipients;
Prothioconazole is present in an amount in the range from 12 to 20% w/w and Cymoxanil is present in an amount in the range from 6 to 10% w/w and Picoxystrobin is present in an amount in the range from 10 to 18% w/w and agriculturally acceptable excipients;
Prothioconazole is present in an amount in the range from 12 to 20% w/w and Cymoxanil is present in an amount in the range from 6 to 8% w/w and Pyraclostrobin is present in an amount in the range from 6 to 8% w/w and agriculturally acceptable excipients;
Prothioconazole is present in an amount in the range from 15 to 25% w/w and Cymoxanil is present in an amount in the range from 5.5 to 9% w/w and Pyraoxystrobin is present in an amount in the range from 5.5 to 8% w/w and agriculturally acceptable excipients;
Prothioconazole is present in an amount in the range from 12 to 20% w/w and Cymoxanil is present in an amount in the range from 6 to 8% w/w and Trifloxystrobin is present in an amount in the range from 1 to 3% w/w and agriculturally acceptable excipients;
Prothioconazole is present in an amount in the range from 15 to 20% w/w and Dimethomorph is present in an amount in the range from 20 to 30% w/w and Fenaminstrobin is present in an amount in the range from 7.5 to 10% w/w and agriculturally acceptable excipients;
Prothioconazole is present in an amount in the range from 15 to 25% w/w and Dimethomorph is present in an amount in the range from 20 to 30% w/w and Pyraoxystrobin is present in an amount in the range from 5 to 8% w/w and agriculturally acceptable excipients;
In another embodiment, the compositions of the present invention are formulated as Suspension concentrate (SC), Dispersible concentrate (DC), Dustable powder (DP), Powder for dry seed treatment (DS), Flowable concentrate for seed treatment (FS), Oil-dispersion (OD), Water dispersible granules (WDG/WG), Wettable powder (WP), Water dispersible powder for slurry seed treatment (WS), Water dispersible tablet (WT) preferably Suspension concentrate (SC), and Wettable powder (WP).
In one other embodiment, the compositions of the present invention comprises one or more agriculturally acceptable excipient selected from the group comprising of dispersing agent(s), wetting agent(s), dispersing cum wetting agent(s), disintegrating agent(s), defoaming agent(s) / defoamer(s) / antifoaming agent(s) / antifoamer(s), biocide(s)/preservative(s), viscosity modifier(s)/ rheology modifier(s)/ thickener(s), anti-freeze agent(s), pH modifier(s), pH stabilizer(s), anti-caking agent(s), solvent(s), filler(s), diluent(s) or a combination thereof and other excipients as will be required in a particular type of formulation.
The compositions of present invention uses dispersing agents to prevent agglomeration of solid particles and keep them suspended in fluid. Non-limiting examples of dispersing agent that can be used in the present invention include, but not limited to polymethyl methacrylate-polyethylene glycol graft copolymer, acrylate copolymer liquid dispersant, condensed methyl naphthalene sulfonate sodium salt, acrylate copolymer grafted with PEG, polyoxy ethylene alkyl aryl phosphate amine salt, poly-carboxylate dispersant, sodium polycarboxylate, modified styrene acrylic polymeric dispersant, sodium lignosulphonate, sodium salt of naphthalene sulfonate condensate, ethoxylated polyarylphenol phosphate amine salt, polymethyl methacrylate-polyethylene oxide graft copolymer, graft copolymer of polymethyl methacrylate-polyethylene glycol, ethoxylated isodecyl alcohol, blend of acrylic graft copolymer and emulsifier, tristyrylphenol ethoxylate, anionic tristyrylphenol phosphate surfactant, non-ionic surfactant, polyalkoxylated butyl ether dispersant, sodium alkylnaphthalene sulfonate condensate, sodium naphthalene sulphonate salt, sodium alkylnaphthalene sulfonate phenol condensate, sodium alkylnaphthalene sulfonate formaldehyde condensate, modified styrene acrylic polymeric aqueous dispersant, proprietary blend of phosphate ester and sodium naphthalene sulphate formaldehyde condensate, lignosulfonic acid dispersant, kraft lignosulfonate with a low degree sulfonation, modified sodium lignosulphonate, naphthalene sulfonate formaldehyde condensate, mixture of salt of naphthalene sulphonic acid and phenol, alkyl naphthalene sulfonate sodium salt, modified naphthalene sulfonate formaldehyde condensate, highly sulfonated kraft lignin, naphthalene sulfonate phenol condensate, sodium isopropyl naphthalene sulfonate. One or more dispersing agents may be used in the compositions of the present invention. Dispersing agents is present in an amount in the range from 0.1 to 20% w/w;
The compositions of present invention uses wetting agent to facilitate the process of dispersion of the granules in the liquid. Non-limiting examples of wetting agents that can be used in the present invention include, but not limited to polyoxyethylene alkyl ether, sodium alkyl naphthalene sulfonate blend, Adsee 2610 (non-ionic proprietary blend of supplier), polyalkylene oxide block copolymer, ethoxylated tristyrylphenol, sodium isopropyl naphthalene sulfonate, sodium butyl naphthalene sulfonate, sodium dioctylsulphosuccinate, branched short chain alcohol ethoxylate wetter, sodium alkyl naphthalene sulfonate with an anionic blend, polyalkylene glycol ether, EO/PO block co-polymer, sodium alkyl naphthalene sulfonate blend with a anionic blend, nonionic proprietary surfactant blend, sulphonated anionic wetter, copolymer condensate of ethylene and propylene oxide, ethoxylated isodecyl alcohol, sodium alkyl naphthalene sulfonate formaldehyde condensate, comb-type polymeric surfactant, ethoxylated polyarylphenol phosphate amine salt, dibutyl naphthalene sulfonic acid sodium salt, dialkyl naphthalene sulphonate. One or more wetting agent may be used in the compositions of the present invention. Wetting agent is present in an amount in the range from 0.1-10% w/w;
The compositions of present invention also uses dispersing cum wetting agent. Non-limiting examples of dispersing cum wetting agent that can be used in the present invention include, but not limited to proprietary blend of phosphate ester and sodium naphthalene sulphate formaldehyde condensate, Jeemox SCR (proprietary blend of supplier), modified styrene acrylic polymeric dispersant, highly sulfonation and low molecular weight kraft lignin polymer, sodium salt of aromatic ring surfactant, ammonium salt of aromatic ring surfactant, sodium salt of naphthalene sulphonic acid condensation, proprietary blend of anionic surfactant, proprietary blend of polymeric surfactant, sodium methyl oleoyl taurate, tristyrylphenol ethoxylate phosphate ester. One or more dispersing cum wetting agent may be used in the compositions of the present invention. Dispersing cum wetting agent is present in an amount in the range from 2-10% w/w;
The compositions of present invention uses anti-freeze agent which are used to prevent deleterious effects due to freezing and lyophilization (lyophilisation). Suitable anti-freeze agent used herein, but not limited to glycerol, propylene glycol, diethylene glycol, monoethylene glycol. One or more anti-freeze agent may be used in the compositions of the present invention. Anti-freeze agent is present in an amount in the range from 1 to 10% w/w.
The compositions of present invention also uses defoaming agent. The term “defoaming agent(s)” or “defoamer(s)” or “antifoaming agent(s)” “antifoamer(s)” refers to a chemical additive that reduces and hinders the formation of foam in liquid, semi-solid, or solid formulations. The terms defoaming agent and anti-foaming agent can be used interchangeably. Suitable defoamer used herein, but not limited to, polydimethylsiloxane antifoam emulsion, silicon emulsion, polysiloxane emulsion, organic fluorine compounds. One or more defoaming agent may be used in the compositions of the present invention. Defoaming agent is present in in an amount in the range from 0.01 to 2% w/w.
The compositions of present invention uses biocide/preservatives to prevent the composition from spoilage due to bacteria, yeasts and fungi or deterioration due to undesirable chemical changes. Suitable biocide/preservative used herein, but not limited to 20% aqueous dipropylene glycol solution of 1, 2- benzisothiazolin-3-one, formaldehyde, potassium sorbate, 4-hydroxybenzoic acid esters, 2-methyl-4-isothiazolin-3-one, 5-chloro-2-methyl-4-isothiazolin-3-one. One or more biocide/preservatives may be used in the compositions of the present invention. Biocide/preservatives is present in an amount in the range from 0.01-1% w/w.
The compositions of present invention uses thickener which are usually polymeric material, and at a low concentration increases the viscosity of an aqueous solution and helps to stabilize the composition. Suitable thickener used herein, but not limited to, xanthan gum, welan gum, guar gum, polyvinyl alcohol, carboxymethylcellulose, polyvinylpyrrolidone, carboxyvinyl polymer, acrylic polymer, starch derivative, polysaccharide, high purity silica, white carbon. One or more thickener may be used in the compositions of the present invention. Thickener is present in an amount in the range from 0.1-5% w/w.
The compositions of present invention uses pH stabilizer. Suitable pH stabilizer that may be used in the compositions of the present invention is citric acid and present in an amount in the range from 0.1 to 1.0% w/w.
The compositions of present invention uses anticaking agent. Suitable anticaking agent used herein, but not limited to, precipitated silica, organic bentonite, polyolefin particles, fumed silica. One or more anticaking agent may be used in the compositions of the present invention. Anticaking agent is present in an amount in the range from 1 to 3% w/w;
The compositions of present invention uses filler. Suitable fillers used herein, but not limited to, silica, precipitated silica, sodium bicarbonate, china clay, lactose, bentonite clay, kaolin, diatomaceous earth. One or more filler may be used in the compositions of the present invention. The filler may be used in an amount of quantity sufficient to make 100% w/w formulation.
The compositions of present invention uses diluents. Suitable diluents that may be used in the composition of the present invention is demineralised water and present in an amount quantity sufficient to make 100% w/w formulation.
In an embodiment, the present invention provides a process of preparation of the compositions comprising first fungicide A, Prothioconazole and second fungicide B, selected from Cyazofamid, Cymoxanil or Dimethomorph; and third fungicide C, selected from Azoxystrobin, Fenaminstrobin, Picoxystrobin, Pyraclostrobin, Pyraoxystrobin or Trifloxystrobin and agriculturally acceptable excipient(s).
In an embodiment, the present invention provides a process for the preparation of a suspension concentrate (SC) formulations which comprises: a) diluting and solubilizing a biocide, defoamer and antifreeze agent in demineralised water in a mixing vessel and adding dispersing and wetting agent under stirring to get homogeneous mixture; b) adding active ingredients one by one under stirring and mixing till homogeneous slurry obtained; c) wet grinding at suitable temperature till desired particle size obtained, and d) adding previously prepared viscosity modifier solution and stirring to obtain suspension concentrate formulation.

In an embodiment, the present invention provides a process for the preparation of a wettable powder (WP) formulation which comprises: a) weighing and mixing of required active ingredients and other ingredients; b) milling in a suitable air jet mill; c) grinding the material to obtain desired particle size (D90- <10 micron) and d) mixing homogeneously in a blender to obtain the wettable powder formulation.

The compositions of this invention are useful as plant disease control agents. The present invention therefore further comprises a method for controlling plant diseases caused by fungal plant pathogens comprising applying to the plant or plants portions such as seeds, seedlings, saplings, roots, tubers, stems, leaves, stalks, foliage and fruits to be protected an effective amount of one or more of aforesaid fungicidal composition.
The compositions of the present invention can be applied by any one of the methods selected from atomization, spreading, dusting, spraying, diffusion, immersion, irrigation (chemigation), mixing, foaming, dressing, coating, blasting, fumigation, smoking, smog and painting.

The rate of application amount of the prepared compositions varies depending on, for example, the blending ratio of active ingredients, meteorological condition, dosage form, application time, application method, application place, fungi to be controlled, and a target crop, in ordinary cases.

The compositions of present invention provide controls on variety of diseases such as Fruit rot (Anthracnose), Powdery mildew, Damping off, Leaf spot, Die-back, twig blight, Wilt, Stem Rot, Early & late blight, Ring Rot, Buck eye rot, Alternaria leaf spot, Cercospora leaf spot, Blight, Black Scurf, Scab, Anthracnose, Purple blotch, Stemphylium blight, Black mold and neck rot, Collar rot, Rust, Downey mildew, Angular leafspot, Marssonina leaf blotch, Premature leaf fall, Core rot, Greasy spot, Gummosis (Foot Rot) (Phytophthora palmivora), Root rot, Crown rot, Leaf fall and Brown rot, Sooty mould, Anthracnose leaf spot, Sigatoka leaf spot, Fruit rot, Cigar end rot, Tip rot, Leaf and Fruit spots, Downy leafspot, Black Rot, Grey blight, Blister Blight, red rust, Coffee leaf rust, Leaf blotch, Rhizome rot, Sheath blight, Leaf blast, Brown Spot, Sheath rot, neck blast, False smut, Dirty panicle, Grain discoloration, Leafspot, Grey mildew, Alternaria Leaf blight, Turcicum leaf blight, Seed rot, Seedling blight, Browny stripe, Red rot, Smut, White rust, Early leafspot (Cercospora arachidicola), Late leafspot (C. personata), Loose smut, Yellow rust, Karnal bunt, Leaf blight, Stripe rust, flag smut, Myrothecium leaf spot, Fusarium root rot, Phytophthora root rot, Rhizoctonia seedling blight, Pythium seedling blight, Pod & stem blight, Charcoal rot, Frog eye leaf spot, Wilt (Fusarium oxyspor um), Root rot (Rhizoctonia spp.), Seed and Seedling rot disease, Web blight, Grain smut, Fusarium wilt, Alternaria blight, Blackspot etc. in a variety of crops such as Chilli, Okra, Tomato, Brinjal, Potato, Cucumber, Onion, Cabbage, Cauliflower, Beans, Cowpea, Guar, Pea, Cucurbits, Bitter gourd, Sugar beet, Grapes, Mango, Apple, Citrus, Guava, Banana, Pomegranate, Walnut, Ber, Watermelon, Tea, Coffee, Papaya, Turmeric, Rice, Cotton, Maize, Sugarcane, Mustard, Sunflower, Pulses, Pearl millet, Groundnut, Wheat, Soybean, Chickpea, Tobacco, Black gram/Green gram, Sorghum, Pigeon pea, Opium, Cumin, Rose and many other economically important crops.

The inventors of the present invention have surprisingly found that the compositions of the present invention are synergetic in nature. The synergetic compositions of the present invention are more effective than their individual counterparts or when two actives are taken together. The synergetic composition of the present invention also makes it possible to use markedly smaller quantities of the active ingredients as compared to their individual counterparts. This allows a substantial reduction in the application rates of each of these active ingredients, while maintaining good efficacy. The decrease in application rates reduces treatment cost to the farmer and also eases the burden on the environment both from manufacturing waste and crop protection chemical residues.
The fungicidal compositions of present invention provides a wide spectrum control of fungi-pest and minimizes the risk of development of resistance ultimately, which reflects the delays in emergence of the resistant strains hence provide effective and economical control of undesired fungi-pest.
The fungicidal compositions of the present invention provides a number of other advantages:
Significant increased efficacy in comparison to the other formulations tested during the trials.
Are synergistic hence denies the need of sequential application of solo fungicides to control different fungi spectra thereby reducing the environmental load of fungicides.
Uses lesser amounts of active ingredients hence considerable reduction in cost, which would benefit farmers.
The compositions provided one shot solution to farmers to control broad spectrum of fungi-pests.
Are storage stable.
Are completely safer to crops (non-phytotoxic).
Reduction in environmental load of fungicidal residues.
Reduction in quantity of water required for spray of the product in agriculture fields.
Reduction in generation of empty containers of product, thereby, reducing concerns of their disposal.
Provides a broad range of product choice for effective pest management.

Thus, from the foregoing description, it will be apparent to one of the person skilled in the art that many changes and modifications can be made thereto without departing from the scope of the invention as set forth in the description. Accordingly, it is not intended that the scope of the foregoing description be limited to the description set forth above, but rather that such description be construed as encompassing such features that reside in the present invention, including all the features and embodiments that would be treated as equivalents thereof by those skilled in the relevant art.
The embodiments of the present invention are more particularly described in the following examples that are intended as illustrations only, since numerous modifications and variations within the scope of the present invention will be apparent to those of skill in the art. Unless otherwise noted, all parts, percentages and ratios reported in the following examples are on a weight basis and all reagents used in the examples were obtained or are available from the chemical suppliers.
EXAMPLES
The Fungicidal compositions of the present invention comprising first fungicide A, Prothioconazole and second fungicide B, selected from Cyazofamid, Cymoxanil or Dimethomorph; and third fungicide C, selected from Azoxystrobin, Fenaminstrobin, Picoxystrobin, Pyraclostrobin, Pyraoxystrobin or Trifloxystrobin and agriculturally acceptable excipient(s) in the form of suspension concentrate (SC) and wettable powder (WP) is provided in table 1-56. The unit of each component of the compositions are expressed in “% w/w” i.e. the percentage by weight, relative to the weight of the total solution or composition. All the compositions are prepared by following the processes as disclosed in description. All the prepared compositions of the present invention has been tested for stability/shelf life at accelerated temperature.
Table 1: Examples 1 to 6: Compositions of Prothioconazole + Cyazofamid + Azoxystrobin

SN Ingredients Ingredients Description Eg:1 Eg:2 Eg:3 Eg:4 Eg:5 Eg:6
SC SC SC WP WP WP
% w/w
1 Prothioconazole Tech. (100% Basis) Active Ingredient 15.0 20.0 10.0 15.0 20.0 10.0
2 Cyazofamid Tech. (100% Basis) Active Ingredient 4.5 2.5 6.0 4.5 2.5 6.0
3 Azoxystrobin Tech. (100% Basis) Active Ingredient 8.0 10.0 6.0 8.0 10.0 6.0
4 Propylene glycol Anti-freeze Agent 10.0 7.0 10.0 - - -
5 Polymethyl methacrylate-polyethylene glycol graft copolymer Dispersing Agent 3.0 3.5 2.5 - - -
6 Polyoxyethylene alkyl ether Wetting Agent 1.5 2.0 1.0 - - -
7 Polydimethylsiloxane Antifoam Emulsion Defoamer 0.5 0.7 0.3 - - -
8 Benzisothiazolin-3-one Biocide 0.1 0.1 0.1 - - -
9 Xanthan Gum Thickener 0.3 0.3 0.4 - - -
10 D. M. Water Diluent 57.1 54.0 63.7 - - -
11 Poly-carboxylate dispersant Dispersing Agent - - - 5.0 8.0 6.0
12 Sodium Isopropyl Naphthalene Sulfonate Wetting Agent - - - 2.5 3.5 2.0
13 Silicon base Defoamer Defoamer - - - 0.5 0.6 0.3
14 Precipitated Silica Anti-caking agent - - - 3.0 2.4 2.0
15 China Clay Filler - - - 61.5 53.0 67.7
Total 100 100 100 100 100 100

Table 2: Quantities of ingredients in gram charged to prepare the compositions of Eg 1 and 4 of table 1

SN Ingredients Eg:1 Eg:4
1 Prothioconazole Tech. (Purity 98%) 15.30 15.30
2 Cyazofamid Tech. (Purity 96%) 4.68 4.68
3 Azoxystrobin Tech. (Purity 96%) 8.33 8.33
4 Propylene Glycol 10.00 -
5 Polymethyl methacrylate-polyethylene glycol graft copolymer 3.00 -
6 Polyoxyethylene alkyl ether 1.50 -
7 Polydimethylsiloxane Antifoam Emulsion 0.5 -
8 Benzisothiazolin-3-one 0.10 -
9 Xanthan Gum 0.3 -
10 D. M. Water 56.29 -
11 Poly-carboxylate dispersant - 5.0
12 Sodium Isopropyl Naphthalene Sulfonate - 2.5
13 Silicon base Defoamer - 0.50
14 Precipitated Silica - 3.0
15 China Clay - 60.69
Total 100 100

Table 3: Stability studies of the composition of Eg 1 of table 2

Test parameter FAO Specification ‘0’ day RT 14 days HST at 54 ± 2°C
Prothioconazole Content %w/w Min. 15% (±6%) 15.65% 15.70%
Cyazofamid Content %w/w Min. 4.5% (±10%) 4.47% 4.37%
Azoxystrobin Content %w/w Min. 8% (±10%) 8.06% 8.05%
Prothioconazole Suspensibility %w/w Min. 80% 95.00% 96.2%
Cyazofamid Suspensibility %w/w Min. 80% 98.25% 97.25%
Azoxystrobin Suspensibility %w/w Min. 80% 98.67% 96.15%
Wet Sieve Test (75 µm) Max. 98% material pass through test sieve 99.80% 99.90%
pH 1 % (aqueous solution) 6.0 to 8.0 8.3 6.7
Persistent foam Max. 60 mL after 1 min. 5 ml 5 ml
Specific gravity 1.09 (±0.02) 1.09 --

Table 4: Stability studies of the composition of Eg 4 of table 2

Test parameter FAO Specification ‘0’ day RT 14 days HST at 54 ± 2°C
Prothioconazole Content %w/w Min. 15% (±6%) 15.65% 15.70%
Cyazofamid Content %w/w Min. 4.5% (±10%) 4.47% 4.37%
Azoxystrobin Content %w/w Min. 8% (±10%) 8.06% 8.05%
Prothioconazole Suspensibility %w/w Min. 75% 95.00% 96.2%
Cyazofamid Suspensibility %w/w Min. 80% 98.25% 97.25%
Azoxystrobin Suspensibility %w/w Min. 75% 98.67% 96.15%
Wet Sieve Test (75 µm) Max. 98% material pass through test sieve 99.80% 99.90%
pH 1 % (aqueous solution) 6.0 to 8.0 8.3 6.7
Persistent foam Max. 60 mL after 1 min. 5 ml 5 ml
Wetting Out time Max. 60 Sec after 1 min. 44 sec 48 Sec

Table 5: Examples 7 to 12: Compositions of Prothioconazole + Cyazofamid + Fenaminstrobin

SN Ingredients Ingredients Description Eg:7 Eg:8 Eg:9 Eg:10 Eg:11 Eg:12
SC SC SC WP WP WP
% w/w
1 Prothioconazole Tech. (100% Basis) Active Ingredient 20.0 15.0 17.5 20.0 15.0 17.5
2 Cyazofamid Tech. (100% Basis) Active Ingredient 4.0 6.0 2.0 4.0 6.0 2.0
3 Fenaminstrobin Tech. (100% Basis) Active Ingredient 9.0 5.0 7.0 9.0 5.0 7.0
4 Propylene glycol Anti-freeze Agent 10.0 7.0 7.0 - - -
5 Polymethyl methacrylate-polyethylene glycol graft copolymer Dispersing Agent 3.0 2.5 2.5 - - -
6 Polyoxyethylene alkyl ether Wetting Agent 1 2.0 1.5 1.5 - - -
7 Sodium alkyl naphthalene sulfonate blend Wetting Agent 2 1.0 1.0 1.0 - - -
8 Polydimethylsiloxane Antifoam Emulsion Defoamer 0.3 0.2 0.2 - - -
9 Benzisothiazolin-3-one Biocide 0.1 0.1 0.1 - - -
10 Xanthan Gum Thickener 0.3 0.4 0.4 - - -
11 D. M. Water Diluent 50.3 61.3 60.8 - - -
12 Modified styrene acrylic polymeric Dispersing Agent 1 - - - 4.0 3.0 3.0
13 Sodium butyl naphthalene sulfonate Wetting Agent - - - 2.0 1.5 1.5
14 Sodium lignosulphonate Dispersing Agent 2 - - - 4.0 3.0 3.0
15 Silicon base Defoamer Defoamer - - - 1.0 0.5 0.5
16 Precipitated Silica Anti-caking agent - - - 2.0 2.5 2.5
17 China Clay Filler - - - 54.0 63.5 63.0
Total 100 100 100 100 100 100

Table 6: Quantities of ingredients in gram charged to prepare the compositions of Eg 7 and 10 of table 5

SN Ingredients Eg:7 Eg:10
1 Prothioconazole Tech. (Purity 98%) 20.40 20.4
2 Cyazofamid Tech. (Purity 96%) 4.16 4.16
3 Fenaminstrobin Tech. (Purity 98%) 9.18 9.18
4 Propylene Glycol 10.00 -
5 Polymethyl methacrylate-polyethylene glycol graft copolymer 3.00 -
6 Polyoxyethylene alkyl ether 2.00 -
7 Sodium alkyl naphthalene sulfonate blend 1.00 -
8 Polydimethylsiloxane Antifoam Emulsion 0.3 -
9 Benzisothiazolin-3-one 0.10 -
10 Xanthan Gum 0.3 -
11 D. M. Water 49.56 -
12 Modified styrene acrylic polymeric - 4.0
13 Sodium butyl naphthalene sulfonate - 2.0
14 Sodium lignosulphonate - 4.0
15 Silicon base Defoamer - 1.0
16 Precipitated Silica - 2.0
17 China Clay - 53.26
Total 100 100

Table 7: Stability studies of the composition of Eg 7 of table 6

Test parameter FAO Specification ‘0’ day RT 14 days HST at 54 ± 2°C
Prothioconazole Content %w/w Min. 20.00% (±6%) 19.63% 19.16%
Cyazofamid Content %w/w Min. 4.00% (±10%) 4.18% 4.21%
Fenaminstrobin Content %w/w Min. 9.00% (±10%) 9.35% 9.25
Prothioconazole Suspensibility %w/w Min. 80% 92.8% 88.0%
Cyazofamid Suspensibility %w/w Min. 80% 98.73% 97.45%
Fenaminstrobin Suspensibility %w/w Min. 80% 97.95% 97.41%
Wet Sieve Test (75 µm) Max. 98% material pass through test sieve 99.90% 99.80%
pH 1 % (aqueous solution) 6.0 to 8.0 8.6 7.4
Persistent foam Max. 60 mL after 1 min. 5 ml 5 ml
Specific gravity 1.12 (±0.02) 1.10 --

Table 8: Stability studies of the composition of Eg 10 of table 6

Test parameter FAO Specification ‘0’ day RT 14 days HST at 54 ± 2°C
Prothioconazole Content %w/w Min. 20% (±6%) 20.48% 20.38%
Cyazofamid Content %w/w Min. 4.5% (±10%) 4.59% 4.58%
Fenaminstrobin Content %w/w Min. 9% (±10%) 9.67% 9.6%
Prothioconazole Suspensibility %w/w Min. 75% 84.30% 78.00%
Cyazofamid Suspensibility %w/w Min. 80% 95.55% 92.12%
Fenaminstrobin Suspensibility %w/w Min. 80% 95.22% 87.00%
Wet Sieve Test (75 µm) Max. 98% material pass through test sieve 99.5% 99.1%
pH 1 % (aqueous solution) 6.0 to 8.0 8.1 7.9
Persistent foam Max. 60 mL after 1 min. 45 ml 40 ml
Wetting Out time Max. 60 Sec after 1 min 46 sec 40 sec

Table 9: Examples 13 to 18: Compositions of Prothioconazole + Cyazofamid + Picoxystrobin

SN Ingredients Ingredients Description Eg:13 Eg:14 Eg:15 Eg:16 Eg:17 Eg:18
SC SC SC WP WP WP
% w/w
1 Prothioconazole Tech. (100% Basis) Active Ingredient 15.0 20.0 12.0 15.0 20.0 12.0
2 Cyazofamid Tech.(100% Basis) Active Ingredient 4.5 2.5 6.5 4.5 2.5 6.5
3 Picoxystrobin Tech. (100% Basis) Active Ingredient 15.0 12.0 10.0 15.0 12.0 10.0
4 Propylene glycol Anti-freeze Agent 10.0 10.0 8.0 - - -
5 Acrylate copolymer liquid dispersant Dispersing Agent 3.0 3.0 2.5 - - -
6 Adsee 2610 (non-ionic proprietary blend of supplier) Wetting Agent 2.0 2.0 1.5 - - -
7 Polydimethylsiloxane Antifoam Emulsion Defoamer 0.3 0.3 0.2 - - -
8 Benzisothiazolin-3-one Biocide 0.1 0.1 0.1 - - -
9 Xanthan Gum Thickener 0.3 0.3 0.4 - - -
10 D. M. Water Diluent 49.8 49.8 58.8 - - -
11 Sodium polycarboxylate Dispersing Agent 1 - - - 2.5 2.5 2.0
12 Sodium butyl naphthalene sulfonate Wetting Agent - - - 2.0 2.0 1.5
13 Sodium lignosulphonate Dispersing Agent 2 - - - 5.5 5.5 3.0
14 Silicon base Defoamer Defoamer - - - 0.5 0.5 0.3
15 Precipitated Silica Anti-caking agent - - - 2.0 2.0 3.0
16 China Clay Filler - - - 53.0 53.0 61.7
Total 100 100 100 100 100 100

Table 10: Quantities of ingredients in gram charged to prepare the compositions of Eg 13 and 16 of table 9

SN Ingredients Eg:13 Eg:16
1 Prothioconazole Tech. (Purity 98%) 15.30 15.30
2 Cyazofamid Tech. (Purity 96%) 4.68 4.68
3 Picoxystrobin Tech. (Purity 97%) 15.46 15.46
4 Propylene Glycol 10.00 -
5 Acrylate copolymer liquid dispersant 3.00 -
6 Adsee 2610 (non-ionic proprietary blend of Supplier) 2.00 -
7 Polydimethylsiloxane Antifoam Emulsion 0.3 -
8 Benzisothiazolin-3-one 0.10 -
9 Xanthan Gum 0.3 -
10 D. M. Water 48.86 -
11 Sodium polycarboxylate - 2.5
12 Sodium butyl naphthalene sulfonate - 2.0
13 Sodium lignosulphonate - 5.5
14 Silicon base Defoamer - 0.5
15 Precipitated Silica - 2.0
16 China Clay - 52.00
Total 100 100

Table 11: Stability studies of the composition of Eg 13 of table 10

Test parameter FAO Specification ‘0’ day RT 14 days HST at 54 ± 2°C
Prothioconazole Content %w/w Min. 15% (±6%) 15.25% 15.28%
Cyazofamid Content %w/w Min. 4.5% (±10%) 4.3% 4.06%
Picoxystrobin Content %w/w Min. 15% (±6%) 15.04% 15.05%
Prothioconazole Suspensibility %w/w Min. 80% 96.00% 90.2%
Cyazofamid Suspensibility %w/w Min. 80% 98.73% 97.45%
Picoxystrobin Suspensibility %w/w Min. 80% 98.52% 94.15%
Wet Sieve Test (75 µm) Max. 98% material pass through test sieve 99.90% 99.90%
pH 1 % (aqueous solution) 6.0 to 8.0 8.7 7.9
Persistent foam Max. 60 mL after 1 min. 5 ml 5 ml
Specific gravity 1.12 (±0.02) 1.12 --

Table 12: Stability studies of the composition of Eg 16 of table 10

Test parameter FAO Specification ‘0’ day RT 14 days HST at 54 ± 2°C
Prothioconazole Content %w/w Min. 15% (±6%) 16.09% 16.15%
Cyazofamid Content %w/w Min. 5.0% (±10%) 5.09% 4.57%
Picoxystrobin Content %w/w Min. 15% (±10%) 15.14% 15.1%
Prothioconazole Suspensibility %w/w Min. 75% 78.20% 76.8%
Cyazofamid Suspensibility %w/w Min. 80% 85.04% 82.76%
Picoxystrobin Suspensibility %w/w Min. 80% 97.57% 90.58%
Wet Sieve Test (75 µm) Max. 98% material pass through test sieve 99.21% 99.42%
pH 1 % (aqueous solution) 6.0 to 8.0 9.2 9.1
Persistent foam Max. 60 mL after 1 min. 40 ml 30 ml
Wetting Out time Max. 60 Sec after 1 min 45sec 38 sec

Table 13: Examples 19 to 24: Compositions of Prothioconazole + Cyazofamid + Pyraclostrobin

SN Ingredients Ingredients Description Eg:19 Eg:20 Eg:21 Eg:22 Eg:23 Eg:24
SC SC SC WP WP WP
% w/w
1 Prothioconazole Tech. (100% Basis) Active Ingredient 20.0 16.0 12.0 20.0 16.0 12.0
2 Cyazofamid Tech. (100% Basis) Active Ingredient 2.0 4.0 6.0 2.0 4.0 6.0
3 Pyraclostrobin Tech. (100% Basis) Active Ingredient 6.0 8.0 6.0 6.0 8.0 6.0
4 Propylene glycol Anti-freeze Agent 7.0 7.0 10.0 - - -
5 Polymethyl methacrylate-polyethylene glycol graft copolymer Dispersing Agent 1 3.0 3.5 2.8 - - -
6 Polyoxyethylene alkyl ether Wetting Agent 2.0 2.0 1.5 - - -
7 Condensed methyl naphthalene sulfonate sodium salt Dispersing Agent 2 0.5 0.4 0.3 - - -
8 Polydimethylsiloxane Antifoam Emulsion Defoamer 0.3 0.3 0.3 - - -
9 Benzisothiazolin-3-one Biocide 0.1 0.1 0.1 - - -
10 Xanthan Gum Thickener 0.3 0.3 0.4 - - -
11 D. M. Water Diluent 58.8 58.4 60.7 - - -
12 Sodium salt of naphthalene sulfonate condensate Dispersing Agent - - - 3.0 3.0 2.5
13 Sodium Isopropyl Naphthalene Sulfonate Wetting Agent - - - 2.0 2.0 1.5
14 Proprietary blend of phosphate ester and sodium naphthalene Sulphate formaldehyde condensate Dispersing cut wetting agent - - - 2.0 2.0 1.5
15 Precipitated Silica Anti-caking agent - - - 2.0 2.0 3.0
16 China Clay Filler - - - 62.0 62.0 67.0
17 Silicon base defoamer Defoamer - - - 1.0 1.0 0.5
Total 100 100 100 100 100 100

Table 14: Quantities of ingredients in gram charged to prepare the compositions of Eg 19 and 22 of table 13

SN Ingredients Eg:19 Eg:22
1 Prothioconazole Tech. (Purity 98%) 20.40 20.40
2 Cyazofamid Tech. (Purity 96%) 2.08 2.08
3 Pyraclostrobin Tech. (Purity 98%) 6.12 6.12
4 Propylene Glycol 7.00 -
5 Polymethyl methacrylate-polyethylene glycol graft copolymer 3.00 -
6 Polyoxyethylene alkyl ether 2.00 -
7 Condensed methyl naphthalene sulfonate sodium salt 0.5 -
8 Polydimethylsiloxane Antifoam Emulsion 0.3 -
9 Benzisothiazolin-3-one 0.10 -
10 Xanthan Gum 0.3 -
11 D. M. Water 58.2 -
12 Sodium salt of naphthalene sulfonate condensate - 3.0
13 Sodium Isopropyl Naphthalene Sulfonate - 2.0
14 Proprietary blend of phosphate ester and sodium naphthalene sulphate formaldehyde condensate - 2.0
15 Precipitated Silica - 2.0
16 China Clay - 61.4
17 Silicon base defoamer - 1.0
Total 100 100

Table 15: Stability studies of the composition of Eg 19 of table 14

Test parameter FAO Specification ‘0’ day RT 14 days HST at 54 ± 2°C
Prothioconazole Content %w/w Min. 20.00% (±6%) 20.72 19.31
Cyazofamid Content %w/w Min. 2.00% (±10%) 2.20 2.08
Pyraclostrobin Content %w/w Min. 6.00% (±10%) 6.35 6.10
Prothioconazole Suspensibility %w/w Min. 80% 96.6 88.00
Cyazofamid Suspensibility %w/w Min. 80% 97.47 89.82
Pyraclostrobin Suspensibility %w/w Min. 80% 97.1 93.68
Wet Sieve Test (75 µm) Max. 98% material pass through test sieve 99.38 99.48
pH 1 % (aqueous solution) 6.0 to 8.0 8.6 8.4
Persistent foam Max. 60 mL after 1 min. 4 ml 6 ml
Specific gravity 1.09 (±0.02) 1.09 1.10

Table 16: Stability studies of the composition of Eg 22 of table 14

Test parameter FAO Specification ‘0’ day RT 14 days HST at 54 ± 2°C
Prothioconazole Content %w/w Min. 20.00% (±6%) 20.5 20.35
Cyazofamide Content %w/w Min. 2.00% (±10%) 2.16 2.03
Pyraclostrobin Content %w/w Min. 6.00% (±10%) 6.39 6.29
Prothioconazole Suspensibility %w/w Min. 75% 79.00 78.00
Cyazofamide Suspensibility %w/w Min. 80% 82.52 78.99
Pyraclostrobin Suspensibility %w/w Min. 80% 86.51 81.80
Wet Sieve Test (75 µm) Max. 98% material pass through test sieve 99.4 99.1
pH 1 % (aqueous solution) 6.0 to 8.0 7.6 6.8
Persistent foam Max. 60 mL after 1 min. 50 ml 50 ml
Wetting Out Time Max. 60 sec after 1 min. 10 sec 18 sec

Table 17: Examples 25 to 30: Compositions of Prothioconazole + Cyazofamid + Pyraoxystrobin

SN Ingredients Ingredients Description Eg:25 Eg:26 Eg:27 Eg:28 Eg:29 Eg:30
SC SC SC WP WP WP
% w/w
1 Prothioconazole Tech. (100% Basis) Active Ingredient 20.0 25.0 15.0 20.0 25.0 15.0
2 Cyazofamid Tech. (100% Basis) Active Ingredient 2.5 6.5 4.5 2.5 6.5 4.5
3 Pyraoxystrobin Tech. (100% Basis) Active Ingredient 8.0 6.5 4.5 8.0 6.5 4.5
4 Propylene glycol Anti-freeze Agent 10.0 7.0 8.0 - - -
5 Acrylate copolymer liquid dispersant Dispersing Agent 3.0 3.5 3.0 - - -
6 Adsee 2610 (non-ionic proprietary blend of Supplier) Wetting Agent 2.0 2.5 2.0 - - -
7 Polydimethylsiloxane Antifoam Emulsion Defoamer 0.3 0.5 0.3 - - -
8 Benzisothiazolin-3-one Biocide 0.1 0.2 0.1 - - -
9 Xanthan Gum Thickener 0.3 0.3 0.4 - - -
10 D. M. Water Diluent 53.8 48.1 62.3 - - -
11 Sodium salt of naphthalene sulfonate condensate Dispersing Agent 1 - - - 3.0 4.0 2.5
12 Sodium Isopropyl Naphthalene Sulfonate Wetting Agent - - - 2.0 3.0 1.5
13 Mdified styrene acrylic polymeric Dispersant Dispersing Agent 2 - - - 3.0 4.0 1.6
14 Silicon base defoamer Defoamer - - - 0.5 0.8 0.5
15 Precipitated Silica Anti-caking agent - - - 2.0 3.0 2.5
16 China Clay Filler - - - 59.0 47.2 67.4
Total 100 100 100 100 100 100

Table 18: Quantities of ingredients in gram charged to prepare the compositions of Eg 25 and 28 of table 17

SN Ingredients Eg:25 Eg:28
1 Prothioconazole Tech. (Purity 98%) 20.4 20.4
2 Cyazofamid Tech. (Purity 96%) 2.6 2.55
3 Pyraoxystrobin Tech. (Purity 96%) 8.33 8.33
4 Propylene Glycol 10.00 -
5 Acrylate copolymer liquid dispersant 3.00 -
6 Adsee 2610 (non-ionic proprietary blend of Supplier) 2.00 -
7 Polydimethylsiloxane Antifoam Emulsion 0.3 -
8 Benzisothiazolin-3-one 0.10 -
9 Xanthan Gum 0.3 -
10 D. M. Water 52.97 -
11 Sodium salt of naphthalene sulfonate condensate - 3.0
12 Sodium alkyl naphthalene sulfonate blend - 2.0
13 Modified styrene acrylic polymeric dispersant - 3.0
14 Silicon base defoamer - 0.5
15 Precipitated Silica - 2.0
16 China Clay - 58.22
Total 100 100

Table 19: Stability studies of the composition of Eg 25 of table 18

Test parameter FAO Specification ‘0’ day RT 14 days HST at 54 ± 2°C
Prothioconazole Content %w/w Min. 20% (±6%) 19.29 19.45
Cyazofamid Content %w/w Min. 2.5% (±10%) 2.6 2.23
Pyraoxystrobin Content %w/w Min. 8% (±6%) 8.02 8.22
Prothioconazole Suspensibility %w/w Min. 80% 86.10% 75.2%
Cyazofamid Suspensibility %w/w Min. 80% 97.88 89.75
Pyraoxystrobin Suspensibility %w/w Min. 80% 96.00% 94.86%
Wet Sieve Test (75 µm) Max. 98% material pass through test sieve 99.90% 99.80%
pH 1 % (aqueous solution) 6.0 to 8.0 7.9 7.1
Persistent foam Max. 60 mL after 1 min. 10 ml 14 ml
Specific gravity 1.11 (±0.02) 1.11 1.12-

Table 20: Stability studies of the composition of Eg 28 of table 18

Test parameter FAO Specification ‘0’ day RT 14 days HST at 54 ± 2°C
Prothioconazole Content %w/w Min. 20% (±6%) 20.82% 20.81%
Cyazofamid Content %w/w Min. 2.5% (±10%) 2.59% 2.55%
Pyraoxystrobin Content %w/w Min. 8% (±10%) 8.59% 8.63%
Prothioconazole Suspensibility %w/w Min. 75% 77.34% 75.4%
Cyazofamid Suspensibility %w/w Min. 80% 87.18% 87.57%
Pyraoxystrobin Suspensibility %w/w Min. 80% 95.9% 96.1%
Wet Sieve Test (75 µm) Max. 98% material pass through test sieve 99.21% 99.10%
pH 1 % (aqueous solution) 6.0 to 8.0 9.2 8.6
Persistent foam Max. 60 mL after 1 min. 50 ml 55 ml
Wetting Out time Max. 60 Sec after 1 min 21sec 30 sec

Table 21: Examples 31 to 36: Compositions of Prothioconazole + Cyazofamid + Trifloxystrobin

SN Ingredients Ingredients Description Eg:31 Eg:32 Eg:33 Eg:34 Eg:35 Eg:36
SC SC SC WP WP WP
% w/w
1 Prothioconazole Tech. (100% Basis) Active Ingredient 20.0 15.0 18.0 20.0 15.0 18.0
2 Cyazofamid Tech.(100% Basis) Active Ingredient 3.0 5.0 7.0 3.0 5.0 7.0
3 Trifloxystrobin Tech. (100% Basis) Active Ingredient 3.0 2.0 1.0 3.0 2.0 1.0
4 Propylene glycol Anti-freeze Agent 10.0 8.0 10.0 - - -
5 Polymethyl methacrylate-polyethylene glycol graft copolymer Dispersing Agent 1 2.0 2.5 3.0 - - -
6 Polyalkylene oxide block copolymer Wetting Agent 1.5 2.0 2.5 - - -
7 Acrylate copolymer grafted with PEG Dispersing Agent 2 3.0 3.0 3.5 - - -
8 Polydimethylsiloxane Antifoam Emulsion Defoamer 0.3 0.5 0.3 - - -
9 Benzisothiazolin-3-one Biocide 0.1 0.1 0.1 - - -
10 Xanthan Gum Thickener 0.3 0.4 0.3 - - -
11 D. M. Water Diluent 56.8 61.6 54.3 - - -
12 Sodium Polycarboxylate Dispersing Agent 1 - - - 3.0 3.5 4.0
13 Sodium alkyl naphthalene sulfonate blend Wetting Agent - - - 2.0 2.5 3.0
14 Sodium Lignosulphonate Dispersing Agent 2 - - - 5.0 3.5 5.0
15 Silicon base defoamer Defoamer - - - 0.5 0.8 1.0
16 Precipitated Silica Anti-caking agent - - - 2.0 3.0 2.0
17 China Clay Filler - - - 61.5 64.7 59.0
Total 100 100 100 100 100 100

Table 22: Quantities of ingredients in gram charged to prepare the compositions of Eg 31 and 34 of table 21

SN Ingredients Eg:31 Eg:34
1 Prothioconazole Tech. (Purity 98%) 20.40 20.4
2 Cyazofamid Tech. (Purity 96%) 3.12 3.12
3 Trifloxystrobin Tech. (Purity 98%) 3.1 3.09
4 Propylene Glycol 10.00 -
5 Polymethyl methacrylate-polyethylene glycol graft copolymer 2.00 -
6 Polyalkylene oxide block copolymer 1.5 -
7 Acrylate copolymer grafted with PEG 3.00 -
8 Polydimethylsiloxane Antifoam Emulsion 0.3 -
9 Benzisothiazolin-3-one 0.10 -
10 Xanthan Gum 0.3 -
11 D. M. Water 56.18 -
12 Sodium polycarboxylate - 3.0
13 Sodium alkyl naphthalene sulfonate blend - 2.0
14 Sodium lignosulphonate - 5.0
15 Silicon base defoamer - 0.5
16 Precipitated Silica - 2.0
17 China Clay - 60.89
Total 100 100

Table 23: Stability studies of the composition of Eg 31 of table 22

Test parameter FAO Specification ‘0’ day RT 14 days HST at 54 ± 2°C
Prothioconazole Content %w/w Min. 20.00% (±6%) 20.93 19.14
Cyazofamid Content %w/w Min. 3.00% (±10%) 3.04 3.02
Trifloxystrobin Content %w/w Min. 3.00% (±10%) 3.12 3.14
Prothioconazole Suspensibility %w/w Min. 80% 93.6 93.8
Cyazofamid Suspensibility %w/w Min. 80% 96.84 98.12
Trifloxystrobin Suspensibility %w/w Min. 80% 98.78 98.66
Wet Sieve Test (75 µm) Max. 98% material pass through test sieve 99.94 99.95
pH 1 % (aqueous solution) 6.0 to 8.0 7.6 7.8
Persistent foam Max. 60 mL after 1 min. 10 ml 12 ml
Specific gravity 1.12 (±0.02) 1.11 1.11

Table 24: Stability studies of the composition of Eg 34 of table 22

Test parameter FAO Specification ‘0’ day RT 14 days HST at 54 ± 2°C
Prothioconazole Content %w/w Min. 20% (±6%) 20.82% 20.81%
Cyazofamid Content %w/w Min. 2.5% (±10%) 2.59% 2.55%
Trifloxystrobin Content %w/w Min. 8% (±10%) 8.59% 8.63%
Prothioconazole Suspensibility %w/w Min. 75% 77.34% 75.4%
Cyazofamid Suspensibility %w/w Min. 80% 87.18% 87.57%
Pyraoxystrobin Suspensibility %w/w Min. 80% 95.9% 96.1%
Wet Sieve Test (75 µm) Max. 98% material pass through test sieve 99.21% 99.10%
pH 1 % (aqueous solution) 6.0 to 8.0 9.2 8.6
Persistent foam Max. 60 mL after 1 min. 50 ml 55 ml
Wetting Out time Max. 60 Sec after 1 min 30 sec 25 sec

Table 25: Examples 37 to 42: Compositions of Prothioconazole + Cymoxanil + Azoxystrobin

SN Ingredients Ingredients Description Eg:37 Eg:38 Eg:39 Eg:40 Eg:41 Eg:42
SC SC SC WP WP WP
% w/w
1 Prothioconazole Tech. (100% Basis) Active Ingredient 16.0 20.0 10.0 16.0 20.0 10.0
2 Cymoxanil Tech. (100% Basis) Active Ingredient 8.0 6.0 5.0 8.0 6.0 5.0
3 Azoxystrobin Tech. (100% Basis) Active Ingredient 8.0 10.0 5.0 8.0 10.0 5.0
4 Propylene glycol Anti-freeze Agent 10.0 7.0 10.0 - - -
5 Polymethyl methacrylate-polyethylene glycol graft copolymer Dispersing Agent 3.0 4.0 3.5 - - -
6 Polyoxyethylene alkyl ether Wetting Agent 1.5 2.0 1.5 - - -
7 Citric Acid pH stabilizer 1.0 1.0 1.0 - - -
8 Polydimethylsiloxane Antifoam Emulsion Defoamer 0.5 1.0 0.5 - - -
9 Benzisothiazolin-3-one Biocide 0.1 0.2 0.1 - - -
10 Xanthan Gum Thickener 0.3 0.3 0.4 - - -
11 D. M. Water Diluent 51.6 48.6 63.05
12 Poly-carboxylate dispersant Dispersing Agent - - - 5.0 6.0 4.0
13 Sodium Isopropyl Naphthalene Sulfonate Wetting Agent - - - 2.5 4.0 3.0
14 Silicon base defoamer Defoamer - - - 0.5 1.0 0.5
15 Precipitated Silica Anti-caking agent - - - 3.0 2.0 3.0
16 China Clay Filler - - - 57.0 51.0 69.5
Total 100 100 100 100 100 100

Table 26: Quantities of ingredients in gram charged to prepare the compositions of Eg 37 and 40 of table 25

SN Ingredients Eg:37 Eg:40
1 Prothioconazole Tech. (Purity 98%) 16.32 16.32
2 Cymoxanil Tech. (Purity 97%) 8.24 8.24
3 Azoxystrobin Tech. (Purity 96%) 8.33 8.33
4 Propylene Glycol 10.00 -
5 Polymethyl methacrylate-polyethylene glycol graft copolymer 3.00 -
6 Polyoxyethylene alkyl ether 1.50 -
7 Citric Acid 1.0 -
8 Polydimethylsiloxane antifoam emulsion 0.5 -
9 Benzisothiazolin-3-one 0.10 -
10 Xanthan Gum 0.3 -
11 D. M. Water 50.71 -
12 Poly-carboxylate dispersant - 5.0
13 Sodium Isopropyl Naphthalene Sulfonate. - 2.5
14 Silicon base defoamer - 0.50
15 Precipitated Silica - 3.0
16 China Clay - 56.11
Total 100 100

Table 27: Stability studies of the composition of Eg 37 of table 26

Test parameter FAO Specification ‘0’ day RT 14 days HST at 54 ± 2°C
Prothioconazole Content %w/w Min. 16% (±6%) 16.69% 16.57%
Cymoxanil Content %w/w Min. 8% (±10%) 8.57% 8.51%
Azoxystrobin Content %w/w Min. 8% (±10%) 8.58% 8.55%
Prothioconazole Suspensibility %w/w Min. 80% 93.40% 90.2%
Cymoxanil Suspensibility %w/w Min. 80% 98.50% 97.35%
Azoxystrobin Suspensibility %w/w Min. 80% 98.32% 94.73%
Wet Sieve Test (75 µm) Max. 98% material pass through test sieve 99.21% 99.23%
pH 1 % (aqueous solution) 3.0 to 4.5 3.2 3.2
Persistent foam Max. 60 mL after 1 min. 5 ml 3 ml
Specific gravity 1.11 (±0.02) 1.11 1.09

Table 28: Stability studies of the composition of Eg 40 of table 26

Test parameter FAO Specification ‘0’ day RT 14 days HST at 54 ± 2°C
Prothioconazole Content %w/w Min. 16% (±6%) 16.71% 16.68%
Cymoxanil Content %w/w Min. 8% (±10%) 7.93% 7.81%
Azoxystrobin Content %w/w Min. 8% (±10%) 8.63% 8.50%
Prothioconazole Suspensibility %w/w Min. 75% 78.00% 78.00%
Cymoxanil Suspensibility %w/w Min. 80% 92.46% 87.66%
Azoxystrobin Suspensibility %w/w Min. 75% 75.67% 74.15%
Wet Sieve Test (75 µm) Max. 98% material pass through test sieve 99.80% 99.75%
pH 1 % (aqueous solution) 6.0 to 8.5 8.2 8.3
Persistent foam Max. 60 mL after 1 min. 50 ml 50 ml
Wetting Out time Max. 60 Sec after 1 min. 50 sec 48 Sec

Table 29: Examples 43 to 48: Compositions of Prothioconazole + Cymoxanil + Fenaminstrobin

SN Ingredients Ingredients Description Eg:43 Eg:44 Eg:45 Eg:46 Eg:47 Eg:48
SC SC SC WP WP WP
% w/w
1 Prothioconazole Tech. (100% Basis) Active Ingredient 20.0 20.0 15.0 20.0 20.0 15.0
2 Cymoxanil Tech.(100% Basis) Active Ingredient 5.0 8.0 6.0 5.0 8.0 6.0
3 Fenaminstrobin Tech. (100% Basis) Active Ingredient 7.0 9.0 5.0 7.0 9.0 5.0
4 Propylene glycol Anti-freeze Agent 10.0 8.0 10.0 - - -
5 Polyoxy Ethylene Alkyl Aryl Phosphate Amine Salt Dispersing Agent 3.0 4.0 2.5 - - -
6 Ethoxylated tristyrylphenol Wetting Agent 2.0 3.0 1.5 - - -
7 Citric Acid pH stabilizer 1.0 1.0 1.0 - - -
8 Polydimethylsiloxane Antifoam Emulsion Defoamer 0.3 0.5 0.3 - - -
9 Benzisothiazolin-3-one Biocide 0.1 0.1 0.2 - - -
10 Xanthan Gum Thickener 0.3 0.3 0.4 - - -
11 D. M. Water Diluent 51.3 46.2 58.2 - - -
12 Modified styrene acrylic polymeric Dispersing Agent 1 - - - 4.0 6.0 3.5
13 Sodium butyl naphthalene sulfonate Wetting Agent - - - 2.0 3.0 2.0
14 Sodium lignosulphonate Dispersing Agent 2 - - - 4.0 6.0 3.5
15 Silicon base antifoam Defoamer - - - 1.0 1.0 0.5
16 Precipitated Silica Anti-caking agent - - - 3.0 2.5 3.0
17 China Clay Filler - - - 54.0 44.5 61.5
Total 100 100 100 100 100 100

Table 30: Quantities of ingredients in gram charged to prepare the compositions of Eg 43 and 46 of table 29

SN Ingredients Eg:43 Eg:46
1 Prothioconazole Tech. (Purity 98%) 20.40 20.4
2 Cymoxanil Tech. (Purity 96%) 5.2 5.2
3 Fenaminstrobin Tech. (Purity 98%) 7.14 7.14
4 Propylene Glycol 10.00 -
5 Polyoxy Ethylene Alkyl Aryl Phosphate Amine Salt 3.00 -
6 Ethoxylated tristyrylphenol 2.00 -
7 Citric Acid 1.00 -
8 Polydimethylsiloxane Antifoam Emulsion 0.3 -
9 Benzisothiazolin-3-one 0.10 -
10 Xanthan Gum 0.3 -
11 D. M. Water 51.56 -
12 Modified styrene acrylic polymeric - 4.0
13 Sodium butyl naphthalene sulfonate - 2.0
14 Sodium lignosulphonate - 4.0
15 Silicon base defoamer - 1.0
16 Precipitated Silica - 3.0
17 China Clay - 53.26
Total 100 100

Table 31: Stability studies of the composition of Eg 43 of table 30

Test parameter FAO Specification ‘0’ day RT 14 days HST at 54 ± 2°C
Prothioconazole Content %w/w Min. 20.00% (±6%) 20.2% 20.3%
Cymoxanil Content %w/w Min. 5.00% (±10%) 4.94% 4.99%
Fenaminstrobin Content %w/w Min. 7.00% (±10%) 7.06% 7.00%
Prothioconazole Suspensibility %w/w Min. 80% 97.1% 97.2%
Cymoxanil Suspensibility %w/w Min. 80% 98.71% 97.79%
Fenaminstrobin Suspensibility %w/w Min. 80% 97.61% 97.51%
Wet Sieve Test (75 µm) Max. 98% material pass through test sieve 99.90% 99.80%
pH 1 % (aqueous solution) 3.0 to 4.0 3.20 3.19
Persistent foam Max. 60 mL after 1 min. 15 ml 10 ml
Specific gravity 1.12 (±0.02) 1.12 1.11

Table 32: Stability studies of the composition of Eg 46 of table 30

Test parameter FAO Specification ‘0’ day RT 14 days HST at 54 ± 2°C
Prothioconazole Content %w/w Min. 20% (±6%) 21.09% 20.97%
Cymoxanil Content %w/w Min 5% (±10%) 5.01% 4.98%
Fenaminstrobin Content %w/w Min. 7% (±10%) 7.44% 7.37%
Prothioconazole Suspensibility %w/w Min. 75% 79.30% 76.00%
Cymoxanil Suspensibility %w/w Min. 80% 98.00% 98.00%
Fenaminstrobin Suspensibility %w/w Min. 80% 84.00% 87.00%
Wet Sieve Test (75 µm) Max. 98% material pass through test sieve 99.8% 99.9%
pH 1 % (aqueous solution) 6.0 to 8.0 7.09 7.06
Persistent foam Max. 60 mL after 1 min. 52 ml 56 ml
Wetting Out time Max. 60 Sec after 1 min 35 sec 39 sec

Table 33: Examples 49 to 54: Compositions of Prothioconazole + Cymoxanil + Picoxystrobin

SN Ingredients Ingredients Description Eg:49 Eg:50 Eg:51 Eg:52 Eg:53 Eg:54
SC SC SC WP WP WP
% w/w
1 Prothioconazole Tech. (100% Basis) Active Ingredient 15.0 20.0 12.0 15.0 20.0 12.0
2 Cymoxanil Tech. (100% Basis) Active Ingredient 8.0 6.0 10.0 8.0 6.0 10.0
3 Picoxystrobin Tech.(100% Basis) Active Ingredient 18.0 15.0 10.0 18.0 15.0 10.0
4 Propylene glycol Anti-freeze Agent 7.0 8.0 10.0 - - -
5 Polymethyl methacrylate-polyethylene glycol graft copolymer Dispersing Agent 3.0 3.0 4.0 - - -
6 Polyoxyethylene alkyl ether Wetting Agent 2.0 2.0 2.5 - - -
7 Citric Acid PH stabilizer 1.0 1.0 1.0 - - -
8 Polydimethylsiloxane Antifoam Emulsion Defoamer 0.3 0.3 0.5 - - -
9 Benzisothiazolin-3-one Biocide 0.1 0.2 0.1 - - -
10 Xanthan Gum Thickener 0.3 0.3 0.4 - - -
11 D. M. Water Diluent 45.3 44.3 49.6 - - -
12 Sodium polycarboxylate Dispersing Agent 1 - - - 3.0 3.5 4.0
13 Sodium butyl naphthalene sulfonate Wetting Agent - - - 2.0 2.5 2.5
14 Sodium lignosulphonate Dispersing Agent 2 - - - 6.0 5.0 4.0
15 Silicon base antifoam Defoamer - - - 0.5 0.5 0.8
16 Precipitated Silica Anti-caking agent - - - 3.0 2.5 3.0
17 China Clay Filler - - - 44.5 45.0 53.7
Total 100 100 100 100 100 100

Table 34: Quantities of ingredients in gram charged to prepare the compositions of Eg 49 and 52 of table 33

SN Ingredients Eg:49 Eg:52
1 Prothioconazole Tech. (Purity 98%) 15.30 12.24
2 Cymoxanil Tech. (Purity 96%) 8.33 10.41
3 Picoxystrobin Tech. (Purity 97%) 18.55 10.30
4 Propylene Glycol 7.00 -
5 Polymethyl methacrylate-polyethylene glycol graft copolymer 3.00 -
6 Polyoxyethylene alkyl ether 2.00 -
7 Citric Acid 1.00 -
8 Polydimethylsiloxane antifoam emulsion 0.3 -
9 Benzisothiazolin-3-one 0.10 -
10 Xanthan Gum 0.3 -
11 D. M. Water 44.12 -
12 Sodium polycarboxylate - 3.00
13 Sodium butyl naphthalene sulfonate - 2.0
14 Sodium lignosulphonate - 6.00
15 Silicon base antifoam - 0.5
16 Precipitated Silica - 3.0
17 China Clay - 52.55
Total 100 100

Table 35: Stability studies of the composition of Eg 49 of table 34

Test parameter FAO Specification ‘0’ day RT 14 days HST at 54 ± 2°C
Prothioconazole Content %w/w Min. 15% (±6%) 15.11% 15.22%
Cymoxanil Content %w/w Min. 8% (±10%) 8.07% 8.01%
Picoxystrobin Content %w/w Min. 18% (±6%) 18.52% 18.66%
Prothioconazole Suspensibility %w/w Min. 75% 88.00% 73.2%
Cymoxanil Suspensibility %w/w Min. 80% 98.33% 97.43%
Picoxystrobin Suspensibility %w/w Min. 80% 98.84% 97.5%
Wet Sieve Test (75 µm) Max. 98% material pass through test sieve 99.15% 99.26%
pH 1 % (aqueous solution) 3.0 to 4.5 3.4 3.4
Persistent foam Max. 60 mL after 1 min. 10 ml 12 ml
Specific gravity 1.12 (±0.02) 1.12 --

Table 36: Stability studies of the composition of Eg 52 of table 34
Test parameter FAO Specification ‘0’ day RT 14 days HST at 54 ± 2°C
Prothioconazole Content %w/w Min. 12% (±6%) 12.68% 12.54%
Cymoxanil Content %w/w Min. 10% (±6%) 10.14% 10.1%
Picoxystrobin Content %w/w Min. 10% (±6%) 9.75% 9.52%
Prothioconazole Suspensibility %w/w Min. 75% 77.7% 76.7%
Cymoxanil Suspensibility %w/w Min. 80% 98.45% 92.25%
Picoxystrobin Suspensibility %w/w Min. 80% 96.11% 90.32%
Wet Sieve Test (75 µm) Max. 98% material pass through test sieve 99.9% 99.91%
pH 1 % (aqueous solution) 6.0 to 8.0 8.00 7.90
Persistent foam Max. 60 mL after 1 min. 55 ml 52 ml
Wetting Out time Max. 60 Sec after 1 min 36 sec 39 sec

Table 37: Examples 55 to 60: Compositions of Prothioconazole + Cymoxanil + Pyraclostrobin

SN Ingredients Ingredients Description Eg:55 Eg:56 Eg:57 Eg:58 Eg:59 Eg:60
SC SC SC WP WP WP
% w/w
1 Prothioconazole Tech. (100% Basis) Active Ingredient 20.0 16.0 12.0 20.0 16.0 12.0
2 Cymoxanil Tech. (100% Basis) Active Ingredient 6.0 8.0 6.0 6.0 8.0 6.0
3 Pyraclostrobin Tech. (100% Basis) Active Ingredient 6.0 8.0 6.0 6.0 8.0 6.0
4 Propylene glycol Anti-freeze Agent 7.0 8.0 10.0 - - -
5 Polymethyl methacrylate-polyethylene glycol graft copolymer Dispersing Agent 1 3.0 3.5 3.5 - - -
6 Polyoxyethylene alkyl ether Wetting Agent 2.0 2.5 2.5 - - -
7 Polydimethylsiloxane Antifoam Emulsion Defoamer 0.3 0.5 0.5 - - -
8 Citric Acid pH Stabilizer 1.0 1.0 1.0 - - -
9 Benzisothiazolin-3-one Biocide 0.1 0.1 0.2 - - -
10 Xanthan Gum Thickener 0.3 0.3 0.4 - - -
11 D. M. Water Diluent 54.3 52.1 58.0 - - -
12 Sodium salt of naphthalene sulfonate condensate Dispersing Agent - - - 3.0 5.0 3.5
13 Sodium Isopropyl Naphthalene Sulfonate Wetting Agent - - - 2.0 3.0 3.5
14 Proprietary blend of phosphate ester and sodium naphthalene Sulphate formaldehyde condensate Dispersing cum wetting agent - - - 2.0 3.0 3.0
15 Precipitated Silica Anti-caking agent - - - 2.0 3.0 3.0
16 China Clay Filler - - - 57.2 53.0 62.0
17 Silicon base defoamer Defoamer - - - 1.0 1.0 1.0
Total 100 100 100 100 100 100

Table 38: Quantities of ingredients in gram charged to prepare the compositions of Eg 55 and 58 of table 37

SN Ingredients Eg: 55 Eg: 58
1 Prothioconazole Tech. (Purity 98%) 20.40 20.4
2 Cymoxanil Tech. (Purity 96%) 6.25 6.25
3 Pyraclostrobin Tech. (Purity 98%) 6.12 6.12
4 Propylene Glycol 7.00 -
5 Polymethyl methacrylate-polyethylene glycol graft copolymer 3.00 -
6 Polyoxyethylene alkyl ether 2.00 -
7 Polydimethylsiloxane antifoam emulsion 0.3 -
8 Citric Acid 1.00 -
9 Benzisothiazolin-3-one 0.10 -
10 Xanthan Gum 0.3 -
11 D. M. Water 46.47 -
12 Sodium salt of naphthalene sulfonate condensate - 3.0
13 Sodium Isopropyl Naphthalene Sulfonate - 2.0
14 Proprietary blend of phosphate ester and sodium naphthalene Sulphate formaldehyde condensate - 2.0
15 Precipitated Silica - 2.0
16 China Clay - 57.23
17 Silicon base antifoam - 1.0
Total 100 100

Table 39: Stability studies of the composition of Eg 55 of table 38

Test parameter FAO Specification ‘0’ day RT 14 days HST at 54 ± 2°C
Prothioconazole Content %w/w Min. 20.00% (±6%) 20.43 20.39
Cymoxanil Content %w/w Min. 6.00% (±10%) 6.20 5.73
Pyraclostrobin Content %w/w Min. 6.00% (±10%) 6.28 6.00
Prothioconazole Suspensibility %w/w Min. 75% 96.1 85.01
Cymoxanil Suspensibility %w/w Min. 80% 98.31 88.30
Pyraclostrobin Suspensibility %w/w Min. 80% 98.3 91.18
Wet Sieve Test (75 µm) Max. 98% material pass through test sieve 99.10 99.48
pH 1 % (aqueous solution) 3.0 to 4.5 3.4 3.4
Persistent foam Max. 60 mL after 1 min. 4 ml 6 ml
Specific gravity 1.12 (±0.02) 1.12 1.12

Table 40: Stability studies of the composition of Eg 58 of table 38

Test parameter FAO Specification ‘0’ day RT 14 days HST at 54 ± 2°C
Prothioconazole Content %w/w Min. 20.00% (±6%) 20.98 20.15
Cymoxanil Content %w/w Min. 6.00% (±10%) 6.35 6.34
Pyraclostrobin Content %w/w Min. 6.00% (±10%) 6.24 6.26
Prothioconazole Suspensibility %w/w Min. 75% 77.00 74.40
Cymoxanil Suspensibility %w/w Min. 80% 81.21 87.57
Pyraclostrobin Suspensibility %w/w Min. 80% 98.14 88.59
Wet Sieve Test (75 µm) Max. 98% material pass through test sieve 99.4 99.1
pH 1 % (aqueous solution) 6.0 to 8.0 7.2 7.06
Persistent foam Max. 60 mL after 1 min. 50 ml 50 ml
Wetting Out Time Max. 60 sec after 1 min. 17sec 21 sec

Table 41: Examples 61 to 66: Compositions of Prothioconazole + Cymoxanil + Pyraoxystrobin

SN Ingredients Ingredients Description Eg:61 Eg:62 Eg:63 Eg:64 Eg:65 Eg:66
SC SC SC WP WP WP
% w/w
1 Prothioconazole Tech.(100% Basis) Active Ingredient 20.0 25.0 15.0 20.0 25.0 15.0
2 Cymoxanil Tech. (100% Basis) Active Ingredient 9.0 7.5 5.5 9.0 7.5 5.5
3 Pyraoxystrobin Tech.(100% Basis) Active Ingredient 8.0 6.5 5.5 8.0 6.5 5.5
4 Propylene glycol Anti-freeze Agent 7.0 8.0 10.0 - - -
5 Polymethyl methacrylate-polyethylene glycol graft copolymer Dispersing Agent 3.0 3.5 2.5 - - -
6 Polyoxyethylene alkyl ether Wetting Agent 2.0 2.5 2.0 - - -
7 Citric Acid PH stabilizer 1.0 1.0 0.5 - - -
8 Polydimethylsiloxane Antifoam Emulsion Defoamer 0.3 0.3 0.3 - - -
9 Benzisothiazolin-3-one Biocide 0.1 0.1 0.1 - - -
10 Xanthan Gum Thickener 0.3 0.3 0.4 - - -
11 D. M. Water Diluent 49.3 45.35 58.25 - - -
12 Sodium salt of naphthalene sulfonate condensate Dispersing Agent - - - 3.0 4.0 2.5
13 Sodium Isopropyl Naphthalene Sulfonate Wetting Agent - - - 2.0 2.5 2.5
14 Silicon base defoamer Defoamer - - - 0.5 0.5 0.3
15 Precipitated Silica Anti-caking agent - - - 3.0 2.5 3.0
China Clay Filler - - - 54.5 51.5 65.7
Total 100 100 100 100 100 100

Table 42 Quantities of ingredients in gram charged to prepare the compositions of Eg 61 and 64 of table 41

SN Ingredients Eg:61 Eg: 64
1 Prothioconazole Tech. (Purity 98%) 20.4 20.4
2 Cymoxanil Tech. (Purity 96%) 9.37 9.37
3 Pyraoxystrobin Tech. (Purity 96%) 8.33 8.33
4 Propylene Glycol 7.00 -
5 Polymethyl methacrylate-polyethylene glycol graft copolymer 3.00 -
6 Polyoxyethylene alkyl ether 2.00 -
7 Citric Acid 1.00 -
8 Polydimethylsiloxane antifoam emulsion 0.3 -
9 Benzisothiazolin-3-one 0.10 -
10 Xanthan Gum 0.3 -
11 D. M. Water 48.2 -
12 Sodium salt of naphthalene sulfonate condensate - 3.0
13 Sodium alkyl naphthalene sulfonate blend - 2.0
14 Silicon base antifoam - 0.5
15 Precipitated Silica - 3.0
16 China Clay - 53.4
Total 100 100

Table 43: Stability studies of the composition of Eg 61 of table 42

Test parameter FAO Specification ‘0’ day RT 14 days HST at 54 ± 2°C
Prothioconazole Content %w/w Min. 20% (±6%) 20.35 19.6
Cymoxanil Content %w/w Min. 9% (±6%) 9.11 9.08
Pyraoxystrobin Content %w/w Min. 8% (±6%) 8.28 8.07
Prothioconazole Suspensibility %w/w Min. 80% 98.20% 92.02%
Cymoxanil Suspensibility %w/w Min. 80% 98.56% 98.74%
Pyraoxystrobin Suspensibility %w/w Min. 80% 98.61% 96.83%
Wet Sieve Test (75 µm) Max. 98% material pass through test sieve 99.15% 99.18%
pH 1 % (aqueous solution) 6.0 to 8.0 3.5 3.4
Persistent foam Max. 60 mL after 1 min. 10 ml 14 ml
Specific gravity 1.12 (±0.02) 1.12 1.12-

Table 44: Stability studies of the composition of Eg 64 of table 42
Test parameter FAO Specification ‘0’ day RT 14 days HST at 54 ± 2°C
Prothioconazole Content %w/w Min. 20% (±6%) 20.59% 20.57%
Cymoxanil Content %w/w Min. 9% (±10%) 9.33% 9.3%
Pyraoxystrobin Content %w/w Min. 8% (±10%) 8.2% 8.19%
Prothioconazole Suspensibility %w/w Min. 75% 78.30% 76.12%
Cymoxanil Suspensibility %w/w Min. 80% 90.3% 85.04%
Pyraoxystrobin Suspensibility %w/w Min. 80% 91.18% 92.43%
Wet Sieve Test (75 µm) Max. 98% material pass through test sieve 99.1% 99.9%
pH 1 % (aqueous solution) 6.0 to 8.0 7.1 7.9
Persistent foam Max. 60 mL after 1 min. 50 ml 55 ml
Wetting Out time Max. 60 Sec after 1 min 40 sec 43 sec

Table 45: Examples 67 to 72: Compositions of Prothioconazole + Cymoxanil + Trifloxystrobin

SN Ingredients Ingredients Description Eg:67 Eg:68 Eg:69 Eg:70 Eg:71 Eg:72
SC SC SC WP WP WP
% w/w
1 Prothioconazole Tech. (100% Basis) Active Ingredient 16.0 20.0 12.0 16.0 20.0 12.0
2 Cymoxanil Tech. (100% Basis) Active Ingredient 8.0 6.0 6.0 8.0 6.0 6.0
3 Trifloxystrobin Tech. (100% Basis) Active Ingredient 2.0 1.0 3.0 2.0 1.0 3.0
4 Propylene glycol Anti-freeze Agent 10.0 10.0 7.0 - - -
5 Polymethyl methacrylate-polyethylene glycol graft copolymer Dispersing Agent 3.0 3.5 3.0 - - -
6 Polyalkylene oxide block copolymer Wetting Agent 1.5 2.0 1.0 - - -
7 Citric Acid pH stabilizer 1.0 1.0 1.0 - - -
8 Polydimethylsiloxane Antifoam Emulsion Defoamer 0.3 0.3 0.3 - - -
9 Benzisothiazolin-3-one Biocide 0.1 0.1 0.1 - - -
10 Xanthan Gum Thickener 0.3 0.3 0.4 - - -
11 D. M. Water Diluent 57.9 55.8 66.3 - - -
12 Sodium Polycarboxylate Dispersing Agent 1 - - - 3.0 3.0 3.5
13 Sodium Dioctylsulphosuccinate Wetting Agent - - - 2.0 2.0 2.5
14 Sodium Lignosulphonate Dispersing Agent 2 - - - 5.0 5.0 3.0
15 Silicon base defoamer Defoamer - - - 0.5 0.5 0.3
16 Precipitated Silica Anti-caking agent - - - 2.0 2.0 3.0
17 China Clay Filler - - - 61.5 60.5 66.7
Total 100 100 100 100 100 100

Table 46: Quantities of ingredients in gram charged to prepare the compositions of Eg 67 and 70 of table 45

SN Ingredients Eg:67 Eg:70
1 Prothioconazole Tech. (Purity 98%) 16.32 16.32
2 Cymoxanil Tech. (Purity 96%) 8.33 8.33
3 Trifloxystrobin Tech. (Purity 98%) 2.04 2.04
4 Propylene Glycol 10.00 -
5 Polymethyl methacrylate-polyethylene glycol graft copolymer 3.00 -
6 Polyalkylene oxide block copolymer 1.5 -
7 Citric Acid 1.00 -
8 Polydimethylsiloxane antifoam emulsion 0.3 -
9 Benzisothiazolin-3-one 0.10 -
10 Xanthan Gum 0.25 -
11 D. M. Water 57.14 -
12 Sodium Polycarboxylate - 3.0
13 Sodium Dioctylsulphosuccinate - 2.0
14 Sodium Lignosulphonate - 5.0
15 Silicon base antifoam - 0.5
16 Precipitated Silica - 2.0
17 China Clay - 60.81
Total 100 100

Table 47: Stability studies of the composition of Eg 67 of table 46

Test parameter FAO Specification ‘0’ day RT 14 days HST at 54 ± 2°C
Prothioconazole Content %w/w Min. 16.00% (±6%) 16.3 16.45
Cymoxanil Content %w/w Min. 8.00% (±10%) 8.06 8.07
Trifloxystrobin Content %w/w Min. 2.00% (±10%) 1.97 1.95
Prothioconazole Suspensibility %w/w Min. 80% 94.8 83.3
Cymoxanil Suspensibility %w/w Min. 80% 97.45 84.11
Trifloxystrobin Suspensibility %w/w Min. 80% 98.40 81.33
Wet Sieve Test (75 µm) Max. 98% material pass through test sieve 99.1 99.5
pH 1 % (aqueous solution) 3.0 to 4.5 3.5 3.5
Persistent foam Max. 60 mL after 1 min. 5 ml 4 ml
Specific gravity 1.07 (±0.02) 1.07 1.07

Table 48: Stability studies of the composition of Eg 70 of table 46

Test parameter FAO Specification ‘0’ day RT 14 days HST at 54 ± 2°C
Prothioconazole Content %w/w Min. 16% (±6%) 16.14% 16.28%
Cymoxani Content %w/w Min. 8% (±10%) 8.21% 8.15%
Trifloxystrobin Content %w/w Min. 2% (±10%) 2.14% 2.14%
Prothioconazole Suspensibility %w/w Min. 75% 78.2% 79.7%
Cymoxanil Suspensibility %w/w Min. 80% 98.33% 97.45%
Trifloxystrobin Suspensibility %w/w Min. 80% 87.31% 85.6%
Wet Sieve Test (75 µm) Max. 98% material pass through test sieve 99.29% 99.24%
pH 1 % (aqueous solution) 6.0 to 8.0 9.2 8.6
Persistent foam Max. 60 mL after 1 min. 30 ml 20 ml
Wetting Out time Max. 60 Sec after 1 min 35 sec 30 sec

Table 49: Examples 73 to 78: Compositions of Prothioconazole + Dimethomorph + Fenaminstrobin

SN Ingredients Ingredients Description Eg:73 Eg:74 Eg:75 Eg:76 Eg:77 Eg:78
SC SC SC WP WP WP
% w/w
1 Prothioconazole Tech. (100% Basis) Active Ingredient 20.0 17.5 15.0 20.0 17.5 15.0
2 Dimethomorph Tech. (100% Basis) Active Ingredient 20.0 30.0 25.0 20.0 30.0 25.0
3 Fenaminstrobin Tech. (100% Basis) Active Ingredient 10.0 7.5 9.0 10.0 7.5 9.0
4 Propylene glycol Anti-freeze Agent 5.0 5.0 7.0 - - -
5 Polymethyl methacrylate-polyethylene glycol graft copolymer Dispersing Agent 1.5 2.0 1.5 - - -
6 Polyalkylene oxide block copolymer Wetting Agent 2.5 3.0 2.5 - - -
7 Polydimethylsiloxane Antifoam Emulsion Defoamer 0.3 0.5 0.3 - - -
8 Benzisothiazolin-3-one Biocide 0.1 0.2 0.1 - - -
9 Xanthan Gum Thickener 0.2 0.2 0.2 - - -
10 D. M. Water Diluent 40.4 34.2 39.4 - - -
11 Condensed methyl naphthalene sulfonate sodium salt Dispersing Agent 1 - - - 2.5 3.0 3.5
12 Sodium alkyl naphthalene sulfonate Wetting Agent - - - 1.5 2.0 2.5
13 Sodium Lignosulphonate Dispersing Agent 2 - - - 4.0 5.0 4.0
14 Silicon base defoamer Defoamer - - - 1.0 1.5 1.0
15 Precipitated Silica Anti-caking agent - - - 1.0 2.0 1.5
16 China Clay Filler - - - 40.0 31.5 38.5
Total 100 100 100 100 100 100

Table 50: Quantities of ingredients in gram charged to prepare the compositions of Eg 73 and 76 of table 49

SN Ingredients Eg:73 Eg:76
1 Prothioconazole Tech. (Purity 98%) 20.40 20.40
2 Dimethomorph Tech. (Purity 98%) 20.40 20.40
3 Fenaminstrobin Tech. (Purity 98%) 10.20 10.20
4 Propylene Glycol 5.00 -
5 Polymethyl methacrylate-polyethylene glycol graft copolymer 1.5 -
6 Polyalkylene oxide block copolymer 2.5 -
7 Polydimethylsiloxane Antifoam Emulsion 0.3 -
8 Benzisothiazolin-3-one 0.10 -
9 Xanthan Gum 0.2 -
10 D. M. Water 39.4 -
11 Condensed methyl naphthalene sulfonate sodium salt - 2.5
12 Sodium Isopropyl Naphthalene Sulfonate - 1.5
13 Sodium lignosulphonate - 4.0
14 Precipitated Silica - 2.0
15 Silicon base antifoam - 1.0
16 China Clay - 38
Total 100 100

Table 51: Stability studies of the composition of Eg 73 of table 50

Test parameter FAO Specification ‘0’ day RT 14 days HST at 54 ± 2°C
Prothioconazole Content %w/w Min. 20.00% (±6%) 20.15 20.7
Dimethomorph Content %w/w Min. 20.00% (±10%) 20.23 20.74
Fenaminstrobin Content %w/w Min. 10.00% (±10%) 10.73 10.49
Prothioconazole Suspensibility %w/w Min. 80% 96.9 83.3
Dimethomorph Suspensibility %w/w Min. 80% 98.6 96.63
Fenaminstrobin Suspensibility %w/w Min. 80% 98.37 94.85
Wet Sieve Test (75 µm) Max. 98% material pass through test sieve 99.94 99.95
pH 1 % (aqueous solution) 6.0 to 8.0 7.8 7.1
Persistent foam Max. 60 mL after 1 min. 12 ml 15 ml
Specific gravity 1.19 (±0.02) 1.19 1.19

Table 52: Stability studies of the composition of Eg 76 of table 50

Test parameter FAO Specification ‘0’ day RT 14 days HST at 54 ± 2°C
Prothioconazole Content %w/w Min. 20.00% (±6%) 20.2 20.23
Dimethomorph Content %w/w Min. 20.00% (±10%) 20.21 20.16
Fenaminstrobin Content %w/w Min. 10.00% (±10%) 10.38 10.37
Prothioconazole Suspensibility %w/w Min. 75% 80.3 78.00
Dimethomorph Suspensibility %w/w Min. 80% 85.32 82.52
Fenaminstrobin Suspensibility %w/w Min. 80% 82.00 80.89
Wet Sieve Test (75 µm) Max. 98% material pass through test sieve 99.1 99.9
pH 1 % (aqueous solution) 6.0 to 8.0 7.4 8.1
Persistent foam Max. 60 mL after 1 min. 12 ml 15 ml
Wetting Out time Max. 60 Sec after 1 min. 45 sec 50 sec

Table 53: Examples 79 to 84: Compositions of Prothioconazole + Dimethomorph + Pyraoxystrobin

SN Ingredients Ingredients Description Eg:79 Eg:80 Eg:81 Eg:82 Eg:83 Eg:84
SC SC SC WP WP WP
% w/w
1 Prothioconazole Tech. (100% Basis) Active Ingredient 15.0 25.0 20.0 15.0 25.0 20.0
2 Dimethomorph Tech. (100% Basis) Active Ingredient 30.0 25.0 20.0 30.0 25.0 20.0
3 Pyraoxystrobin Tech. (100% Basis) Active Ingredient 5.0 6.0 8.0 5.0 6.0 8.0
4 Propylene glycol Anti-freeze Agent 5.0 5.0 7.0 - - -
5 Polymethyl methacrylate-polyethylene glycol graft copolymer Dispersing Agent 1.5 2.0 1.5 - - -
6 Polyalkylene oxide block copolymer Wetting Agent 2.5 3.0 2.5 - - -
7 Polydimethylsiloxane Antifoam Emulsion Defoamer 0.3 0.5 0.3 - - -
8 Benzisothiazolin-3-one Biocide 0.1 0.1 0.1 - - -
9 Xanthan Gum Thickener 0.2 0.1 0.2 - - -
10 D. M. Water Diluent 40.4 33.3 40.4 - - -
11 Sodium salt of naphthalene sulfonate condensate Dispersing Agent - - - 3.0 5.0 3.5
12 Sodium alkyl naphthalene sulfonate Wetting Agent - - - 3.0 5.0 3.5
13 Proprietary blend of phosphate ester and sodium naphthalene Sulphate formaldehyde condensate Dispersing cum wetting Agent - - - 3.0 5.0 3.5
14 Silicon base defoamer Defoamer - - - 2.0 2.0 2.0
15 Precipitated Silica Anti-caking agent - - - 1.0 2 1.0
16 China Clay Filler - - - 38.0 25.0 38.5
Total 100 100 100 100 100 100

Table 54: Quantities of ingredients in gram charged to prepare the compositions of Eg 79 and 82 of table 53

SN Ingredients Eg:79 Eg:82
1 Prothioconazole Tech. (Purity 98%) 15.3 15.3
2 Dimethomorph Tech. (Purity 98%) 30.6 30.6
3 Pyraoxystrobin Tech. (Purity 96%) 5.20 5.20
4 Propylene Glycol 5.00 -
5 Polymethyl methacrylate-polyethylene glycol graft copolymer 1.5 -
6 Polyalkylene oxide block copolymer 2.5 -
7 Polydimethylsiloxane antifoam emulsion 0.3 -
8 Benzisothiazolin-3-one 0.10 -
9 Xanthan Gum 0.2 -
10 D. M. Water 39.2 -
11 Sodium salt of naphthalene sulfonate condensate - 3.0
12 Sodium Isopropyl Naphthalene Sulfonate - 3.0
13 Proprietary blend of phosphate ester and sodium naphthalene sulphate formaldehyde condensate - 3.0
14 Precipitated Silica - 2.0
15 China Clay - 36.9
16 Silicon base antifoam - 1.0
Total 100 100

Table 55: Stability studies of the composition of Eg 82 of table 54

Test parameter FAO Specification ‘0’ day RT 14 days HST at 54 ± 2°C
Prothioconazole Content %w/w Min. 15.00% (±6%) 15.81 15.68
Dimethomorph Content %w/w Min. 30.00% (±10%) 30.14 30.02
Pyraoxystrobin Content %w/w Min. 5.00% (±10%) 5.68 5.73
Prothioconazole Suspensibility %w/w Min. 80% 97.3 91.04
Dimethomorph Suspensibility %w/w Min. 80% 98.23 96.72
Pyraoxystrobin Suspensibility %w/w Min. 80% 98.49 97.67
Wet Sieve Test (75 µm) Max. 98% material pass through test sieve 99.27 99.47
pH 1 % (aqueous solution) 6.0 to 8.0 6.8 6.6
Persistent foam Max. 60 mL after 1 min. 5.0 ml 5.0 ml
Specific Gravity 1.17 (±0.02) 1.17 1.16

Table 56: Stability studies of the composition of Eg 79 of table 54

Test parameter FAO Specification ‘0’ day RT 14 days HST at 54 ± 2°C
Prothioconazole Content %w/w Min. 15.00% (±6%) 16.04 15.95
Dimethomorph Content %w/w Min. 30.00% (±10%) 30.37 30.22
Pyraoxystrobin Content %w/w Min. 5.00% (±10%) 5.93 5.91
Prothioconazole Suspensibility %w/w Min. 75% 78.85 76.00
Dimethomorph Suspensibility %w/w Min. 80% 82.65 84.64
Pyraoxystrobin Suspensibility %w/w Min. 80% 92.91 94.82
Wet Sieve Test (75 µm) Max. 98% material pass through test sieve 99.27 99.47
pH 1 % (aqueous solution) 6.0 to 8.0 7.8 7.6
Persistent foam Max. 60 mL after 1 min. 50 ml 50 ml
Wetting Out Time Max. 60 sec after 1 min. 40 sec 38 sec

As evident from the foregoing tables (1-56) that all the desired compositions have been prepared successfully and has been tested for stability/shelf life at accelerated temperature. After 14 days of storage at 54.0 ± 2 °C, there were no significant changes in active ingredient content, suspensibility, wettability, dispersibility, pH and has passes the sieve test. Therefore, it is concluded that compositions of present invention has good stability and shelf life.

BIO-EFFICACY OF THE FUNGICIDAL COMPOSITIONS OF THE PRESENT INVENTION
Experimental trial were conducted to evaluate the fungicidal compositions of the present invention in India against major fungi-pests on Chilli and Potato Crop with ternary compositions of present invention and comparative solo and binary compositions as per the details provided in Table 57-84. The abbreviations used in Table 57-84 are as follows:
TN: Treatment Number;
g.a.i.: gram active ingredients;
ha: hectare;
O=Observed % fungi-pest reduction (%) Calculated using Abbott Formula;
E=Expected % fungi-pest reduction Calculated using Colby Formula;
CR=Colby ratio;
UTC: Untreated control

Experimental design and method for Chilli Crop
The present field experiment were conducted at Baptala of Guntur district of Andhra Pradesh state during the season Rabi-2022 with twenty-two treatments replicated thrice in randomized block design. The popular and widely cultivated Guntur Chilli variety S-4 selected for this experiment was sown in a plot size of 5m X 5m for each replication with a spacing of 50 X 50cm in sandy loam soil. The crop was maintained well by adapting standard agronomic practices. Total two round of sprays were given, 1st at 0 days and 2nd at after 10 days. The observation were recorded on percent disease index and fruit yield. The data on disease incidence were recorded after each application and presented as mean percent PDI of two spray. The first spray of fungicide was done after the first appearances of disease symptoms. Unsprayed plots served as control (Untreated). The applications were carried out by using the hand operated aspire Knapsack sprayer pump fitted with hollow cone nozzle. The required quantity of water volume was used @ 500 litre per hectare. The severity of Chilli die-back disease were recorded on randomly tagged 5 plants per plot by using 0-9 disease rating scale and expressed as Percent Disease index (PDI) (Wheeler, 1969).
The Chilli fruits were harvested periodically and the yield per hectare was calculated and recorded as tones/ha.

Assessment of PDI (Percent Disease Index)

Scale Disease severity / Per cent infection
0 0% (No symptom)
1 1-10 %
3 11-25 %
5 26-50 %
7 51-75%
9 >75%

The percent disease index (PDI) was calculated by using the formula given by Wheeler (1969)
Sum of Numerical rating
Percent Disease Index (PDI) = --------------------------------------------------------------
Number of plant assessed x Maximum rating

The % reduction in target pest over control was calculated by using Abbott's formula (Reference: Abbott, W.S. (1925). A method of computing the effectiveness of an insecticide. J. Econ. Entomol.; 18 : 265-267.
Corrected % = (1 - n in T after treatment
-----------------------------
n in Co after treatment
) X 100

Where: n = Percent PDI, T = treated, Co = control

Experimental design and method for Potato Crop
The present field experiment were conducted at Aligarh district of Uttar Pradesh state during the season Rabi-2023 with twenty-two treatments replicated thrice in randomized block design. The popular and widely cultivated Potato variety Kufri Ashoka selected for this experiment was sown in a plot size of 4m X 4m for each replication with a spacing of 60 X 20cm in sandy loam soil. The crop was maintained well by adapting standard agronomic practices. Total two round of sprays were given, 1st at 0 days and 2nd at after 10 days. The observation were recorded on disease incidence and fruit yield. The data on disease incidence were recorded after each application and presented as mean percent PDI of two spray. The first spray of fungicide was done after the first appearances of disease symptoms. Unsprayed plots served as control (Untreated). The applications were carried out by using the hand operated aspire Knapsack sprayer pump fitted with hollow cone nozzle. The required quantity of water volume was used @ 500 litre per hectare. The disease severity of late blight of potato were recorded from randomly selected 10 plants per plot and 1 upper leaf, 1 middle leaf and 1 lower leaf of each plant and percent disease index (PDI) is calculated by using the formula given by Wheeler (1969). The % reduction in target pest over control was calculated by using Abbott's formula as given above.
The Potato tuber were harvested periodically and the yield per hectare was calculated and recorded as tones/ha.
Assessment of PDI (Percent Disease Index)
Rating scale for the assessment of late blight severity on potato leaves
Scale Disease incidence (% ) Level of resistance/susceptibility
0 No disease Small lesion on the inoculated point with the lesion area
1 10% Less than 10% of the whole leaflet
3 10% and 20% Lesion area between 10% and 20% of the whole leaflet
5 20% and 30% Lesion area between 20% and 30% of the whole leaflet, Waterish area less than 50% of the whole leaflet
7 30% and 60% Lesion area between 30% and 60%
9 Over 60% Lesion area over 60% of the whole leaflet

Evaluation of synergistic effect
A synergistic effect exists whenever the action of an active ingredient combination is greater than the sum of the actions of the individual components. Synergism was calculated by using Colby’s method, Weeds, vol. 15 No. 1(Jan 1967), pp. 20-2.
The synergistic action expected for a given combination of two active components can be calculated as follows:
?(E=(X+Y) - ((XY))/100 ) ?( )
The synergistic action expected for a given combination of three active components can be calculated as follows:
?(E=(X+Y+Z) - ((XY+YZ+XZ))/100 +) ?( XYZ/10000)
Where:
E represents expected percentage of control for the combination of the three active ingredients at defined doses (for example equal to x, y and z respectively),
X is the percentage of control observed by the compound (I) at a defined dose (equal to x),
Y is the percentage of control observed by the compound (II) at a defined dose (equal to y),
Z is the percentage of control observed by the compound (III) at a defined dose (equal to z).
If observed control of the combination > Expected control, the combination is synergistic (Colby ratio > 1)
If observed control of the combination < Expected control, the combination is antagonistic (Colby ratio < 1)
If observed control of the combination = Expected control, the combination is additive (Colby ratio =1)
Table 57: Efficacy of Fungicidal Compositions of Prothioconazole + Cyazofamid + Azoxystrobin in Potato Crop against Late blight

TN Treatments a.i. % Dose Mean after two applications E CR
g. a.i. / ha gm - ml /ha Late blight
PDI% %ROC
T1 Prothioconazole 20% + Cyazofamid 2.5% + Azoxystrobin 10% SC 20+2.5+10 200+25+100 1000 10.40 80.00 43.30 1.85
T2 Prothioconazole 15% + Cyazofamid 4.5% + Azoxystrobin 8% SC 15+4.5+8 150+45+80 1000 11.44 78.00 45.79 1.70
T3 Prothioconazole 10% + Cyazofamid 6% + Azoxystrobin 6% WP 10+6+6 100+60+60 1000 12.48 76.00 44.73 1.70
T4 Prothioconazole 25% EC + Cyazofamid 34.5% SC 25% EC + 34.5% SC 200+25 700 + 200 33.28 36.00 37.00 0.97
T5 Prothioconazole 25% EC + Cyazofamid 34.5% SC 25% EC + 34.5% SC 150+45 700 + 200 33.80 35.00 38.40 0.91
T6 Prothioconazole 25% EC + Cyazofamid 34.5% SC 25% EC + 34.5% SC 100+60 700 + 200 34.84 33.00 37.90 0.87
T7 Prothioconazole 25% EC + Azoxystrobin 23% SC 25% EC + 23% SC 200+100 700 + 500 43.68 16.00 19.00 0.84
T8 Prothioconazole 25% EC + Azoxystrobin 23% SC 25% EC + 23% SC 150+80 700 + 500 44.20 15.00 22.56 0.66
T9 Prothioconazole 25% EC + Azoxystrobin 23% SC 25% EC + 23% SC 100+60 700 + 500 45.76 12.00 19.90 0.60
T10 Cyazofamid 34.5% SC + Azoxystrobin 23% SC 34.5% SC + 23% SC 25+100 200 + 500 33.80 35.00 37.00 0.95
T11 Cyazofamid 34.5% SC + Azoxystrobin 23% SC 34.5% SC + 23% SC 45+80 200 + 500 34.32 34.00 38.40 0.89
T12 Cyazofamid 34.5% SC + Azoxystrobin 23% SC 34.5% SC + 23% SC 60+60 200 + 500 34.84 33.00 38.59 0.86
T13 Prothioconazole 25% EC 25% EC 200 700 46.80 10.00 - -
T14 Prothioconazole 25% EC 25% EC 150 700 45.76 12.00 - -
T15 Prothioconazole 25% EC 25% EC 100 700 46.80 10.00 - -
T16 Cyazofamid 34.5% SC 34.5% SC 25 200 36.40 30.00 - -
T17 Cyazofamid 34.5% SC 34.5% SC 45 200 36.40 30.00 - -
T18 Cyazofamid 34.5% SC 34.5% SC 60 200 35.88 31.00 - -
T19 Azoxystrobin 23% SC 23% SC 100 500 46.80 10.00 - -
T20 Azoxystrobin 23% SC 23% SC 80 500 45.76 12.00 - -
T21 Azoxystrobin 23% SC 23% SC 60 500 46.28 11.00 - -
T22 Untreated Control - - - 52.00 - - -

Table 58: Effect on yield of Fungicidal Compositions of table 57

TN Treatments a.i. % Dose Yield (t/ha) % Yield increase over control E CR
g. a.i. / ha gm - ml /ha

T1 Prothioconazole 20% + Cyazofamid 2.5% + Azoxystrobin 10% SC 20+2.5+10 200+25+100 1000 38.00 245.45 34.18 1.11
T2 Prothioconazole 15% + Cyazofamid 4.5% + Azoxystrobin 8% SC 15+4.5+8 150+45+80 1000 37.00 236.36 36.07 1.03
T3 Prothioconazole 10% + Cyazofamid 6% + Azoxystrobin 6% WP 10+6+6 100+60+60 1000 37.00 236.36 36.14 1.02
T4 Prothioconazole 25% EC + Cyazofamid 34.5% SC 25%EC + 34.5% SC 200+25 700 + 200 20.00 81.82 25.20 0.79
T5 Prothioconazole 25% EC + Cyazofamid 34.5% SC 25%EC + 34.5% SC 150+45 700 + 200 18.40 67.27 27.35 0.67
T6 Prothioconazole 25% EC + Cyazofamid 34.5% SC 25%EC + 34.5% SC 100+60 700 + 200 16.00 45.45 27.84 0.57
T7 Prothioconazole 25% EC + Azoxystrobin 23% SC 25% EC + 23% SC 200+100 700 + 500 17.00 54.55 22.56 0.75
T8 Prothioconazole 25% EC + Azoxystrobin 23% SC 25% EC + 23% SC 150+80 700 + 500 16.20 47.27 22.03 0.74
T9 Prothioconazole 25% EC + Azoxystrobin 23% SC 25% EC + 23% SC 100+60 700 + 500 17.30 57.27 22.12 0.78
T10 Cyazofamid 34.5% SC + Azoxystrobin 23% SC 34.5% SC + 23% SC 25+100 200 + 500 16.00 45.45 25.20 0.63
T11 Cyazofamid 34.5% SC + Azoxystrobin 23% SC 34.5% SC + 23% SC 45+80 200 + 500 17.20 56.36 27.84 0.62
T12 Cyazofamid 34.5% SC + Azoxystrobin 23% SC 34.5% SC + 23% SC 60+60 200 + 500 18.00 63.64 22.12 0.81
T13 Prothioconazole 25% EC 25% EC 200 700 12.00 9.09 - -
T14 Prothioconazole 25% EC 25% EC 150 700 11.40 3.64 - -
T15 Prothioconazole 25% EC 25% EC 100 700 12.00 9.09 - -
T16 Cyazofamid 34.5% SC 34.5% SC 25 200 15.00 36.36 - -
T17 Cyazofamid 34.5% SC 34.5% SC 45 200 18.00 63.64 - -
T18 Cyazofamid 34.5% SC 34.5% SC 60 200 18.00 63.64 - -
T19 Azoxystrobin 23% SC 23% SC 100 500 12.00 9.09 - -
T20 Azoxystrobin 23% SC 23% SC 80 500 12.00 9.09 - -
T21 Azoxystrobin 23% SC 23% SC 60 500 11.50 4.55 - -
T22 Untreated Control - - - 11.00 - - -

Table 59: Efficacy of Fungicidal Compositions of Prothioconazole + Cyazofamid + Fenaminstrobin in Potato Crop against Late blight

TN Treatments a.i. % Dose Mean after two applications E CR
g. a.i. / ha gm - ml /ha Late blight
PDI% %ROC
T1 Prothioconazole 20% + Cyazofamid 4% + Fenaminstrobin 9% SC 20+4+9 200+40+90 1000 10.00 80.00 51.46 1.55
T2 Prothioconazole 15% + Cyazofamid 6% + Fenaminstrobin 5% SC 15+6+5 150+60+50 1000 12.50 75.00 49.82 1.51
T3 Prothioconazole 17.5% + Cyazofamid 2% + Fenaminstrobin 7% WP 17.5+2+7 175+20+70 1000 11.00 78.00 48.91 1.59
T4 Prothioconazole 25% EC + Cyazofamid 34.5% SC 25% EC + 34.5% SC 200+40 700 + 200 30.00 40.00 40.80 0.98
T5 Prothioconazole 25% EC + Cyazofamid 34.5% SC 25% EC + 34.5% SC 150+60 700 + 200 32.00 36.00 40.96 0.88
T6 Prothioconazole 25% EC + Cyazofamid 34.5% SC 25% EC + 34.5% SC 175+20 700 + 200 31.00 38.00 38.44 0.99
T7 Prothioconazole 25% EC + Fenaminstrobin 20% SC 25% EC + 20% SC 200+90 700 + 500 39.00 22.00 34.40 0.64
T8 Prothioconazole 25% EC + Fenaminstrobin 20% SC 25% EC + 20% SC 150+50 700 + 500 38.00 24.00 30.30 0.79
T9 Prothioconazole 25% EC + Fenaminstrobin 20% SC 25% EC + 20% SC 175+70 700 + 500 37.00 26.00 32.77 0.79
T10 Cyazofamid 34.5% SC + Fenaminstrobin 20% SC 34.5% SC + 20% SC 40+90 200 + 500 31.00 38.00 39.32 0.97
T11 Cyazofamid 34.5% SC + Fenaminstrobin 20% SC 34.5% SC + 20% SC 60+50 200 + 500 31.50 37.00 38.80 0.95
T12 Cyazofamid 34.5% SC + Fenaminstrobin 20% SC 34.5% SC + 20% SC 20+70 200 + 500 32.00 36.00 36.92 0.98
T13 Prothioconazole 25% EC 25% EC 200 700 40.00 20.00 - -
T14 Prothioconazole 25% EC 25% EC 150 700 41.00 18.00 - -
T15 Prothioconazole 25% EC 25% EC 175 700 40.50 19.00 - -
T16 Cyazofamid 34.5% SC 34.5% SC 40 200 37.00 26.00 - -
T17 Cyazofamid 34.5% SC 34.5% SC 60 200 36.00 28.00 - -
T18 Cyazofamid 34.5% SC 34.5% SC 20 200 38.00 24.00 - -
T19 Fenaminstrobin 20% SC 20% SC 90 500 41.00 18.00 - -
T20 Fenaminstrobin 20% SC 20% SC 50 500 42.50 15.00 - -
T21 Fenaminstrobin 20% SC 20% SC 70 500 41.50 17.00 - -
T22 Untreated Control - - - 50.00 - - -

Table 60: Effect on yield of Fungicidal Compositions of table 59

TN Treatments a.i. % Dose Yield (t/ha) % Yield increase over control E CR
g.a.i. / ha gm - ml /ha

T1 Prothioconazole 20% + Cyazofamid 4% + Fenaminstrobin 9% SC 20+4+9 200+40+90 1000 39.00 225.00 37.64 1.04
T2 Prothioconazole 15% + Cyazofamid 6% + Fenaminstrobin 5% SC 15+6+5 150+60+50 1000 37.00 208.33 36.47 1.01
T3 Prothioconazole 17.5% + Cyazofamid 2% + Fenaminstrobin 7% WP 17.5+2+7 175+20+70 1000 38.20 218.33 36.25 1.05
T4 Prothioconazole 25% EC + Cyazofamid 34.5% SC 25% EC + 34.5% SC 200+40 700 + 200 25.00 108.33 27.15 0.92
T5 Prothioconazole 25% EC + Cyazofamid 34.5% SC 25% EC + 34.5% SC 150+60 700 + 200 22.00 83.33 26.39 0.83
T6 Prothioconazole 25% EC + Cyazofamid 34.5% SC 25% EC + 34.5% SC 175+20 700 + 200 24.00 100.00 25.87 0.93
T7 Prothioconazole 25% EC + Fenaminstrobin 20% SC 25% EC + 20% SC 200+90 700 + 500 18.20 51.67 27.15 0.67
T8 Prothioconazole 25% EC + Fenaminstrobin 20% SC 25% EC + 20% SC 150+50 700 + 500 16.40 36.67 25.44 0.64
T9 Prothioconazole 25% EC + Fenaminstrobin 20% SC 25% EC + 20% SC 175+70 700 + 500 17.20 43.33 26.30 0.65
T10 Cyazofamid 34.5% SC + Fenaminstrobin 20% SC 34.5% SC + 20% SC 40+90 200 + 500 16.30 35.83 26.73 0.61
T11 Cyazofamid 34.5% SC + Fenaminstrobin 20% SC 34.5% SC + 20% SC 60+50 200 + 500 17.45 45.42 26.47 0.66
T12 Cyazofamid 34.5% SC + Fenaminstrobin 20% SC 34.5% SC + 20% SC 20+70 200 + 500 18.22 51.83 26.30 0.69
T13 Prothioconazole 25% EC 25% EC 200 700 14.90 24.17 - -
T14 Prothioconazole 25% EC 25% EC 150 700 13.60 13.33 - -
T15 Prothioconazole 25% EC 25% EC 175 700 14.30 19.17 - -
T16 Cyazofamid 34.5% SC 34.5% SC 40 200 14.40 20.00 - -
T17 Cyazofamid 34.5% SC 34.5% SC 60 200 14.80 23.33 - -
T18 Cyazofamid 34.5% SC 34.5% SC 20 200 13.50 12.50 - -
T19 Fenaminstrobin 20% SC 20% SC 90 500 14.40 20.00 - -
T20 Fenaminstrobin 20% SC 20% SC 50 500 13.70 14.17 - -
T21 Fenaminstrobin 20% SC 20% SC 70 500 14.00 16.67 - -
T22 Untreated Control - - - 12.00 - - -

Table 61: Efficacy of Fungicidal Compositions of Prothioconazole + Cyazofamid + Picoxystrobin in Potato Crop against Late blight

TN Treatments a.i. % Dose Mean after two applications E CR
g.a.i. / ha gm - ml /ha Late blight
PDI% %ROC
T1 Prothioconazole 20% + Cyazofamid 2.5% + Picoxystrobin 12% SC 20+2.5+12 200+25+120 1000 12.50 75.00 42.40 1.77
T2 Prothioconazole 15% + Cyazofamid 4.5% + Picoxystrobin 15% SC 15+4.5+15 150+45+150 1000 17.50 65.00 43.68 1.49
T3 Prothioconazole 12% + Cyazofamid 6.5% + Picoxystrobin 10% WP 12+6.5+10 120+65+100 1000 20.00 60.00 43.30 1.39
T4 Prothioconazole 25% EC + Cyazofamid 34.5% SC 25% EC + 34.5% SC 200+25 700 + 200 33.50 33.00 36.00 0.92
T5 Prothioconazole 25% EC + Cyazofamid 34.5% SC 25% EC + 34.5% SC 150+45 700 + 200 37.50 25.00 29.60 0.84
T6 Prothioconazole 25% EC + Cyazofamid 34.5% SC 25% EC + 34.5% SC 120+65 700 + 200 37.50 25.00 37.00 0.68
T7 Prothioconazole 25% EC + Picoxystrobin 22.52% SC 25% EC + 22.52% SC 200+120 700 + 400 37.50 25.00 28.00 0.89
T8 Prothioconazole 25% EC + Picoxystrobin 22.52% SC 25% EC + 22.52% SC 150+150 700 + 400 37.50 25.00 29.60 0.84
T9 Prothioconazole 25% EC + Picoxystrobin 22.52% SC 25% EC + 22.52% SC 120+100 700 + 400 42.50 15.00 19.00 0.79
T10 Cyazofamid 34.5% SC + Picoxystrobin 22.52% SC 34.5% SC + 22.52% SC 25+120 200 + 400 37.50 25.00 28.00 0.89
T11 Cyazofamid 34.5% SC + Picoxystrobin 22.52% SC 34.5% SC + 22.52% SC 45+150 200 + 400 37.50 25.00 36.00 0.69
T12 Cyazofamid 34.5% SC + Picoxystrobin 22.52% SC 34.5% SC + 22.52% SC 65+100 200 + 400 33.50 33.00 37.00 0.89
T13 Prothioconazole 25% EC 25% EC 200 700 40.00 20.00 - -
T14 Prothioconazole 25% EC 25% EC 150 700 44.00 12.00 - -
T15 Prothioconazole 25% EC 25% EC 120 700 45.00 10.00 - -
T16 Cyazofamid 34.5% SC 34.5% SC 25 200 40.00 20.00 - -
T17 Cyazofamid 34.5% SC 34.5% SC 45 200 40.00 20.00 - -
T18 Cyazofamid 34.5% SC 34.5% SC 65 200 35.00 30.00 - -
T19 Picoxystrobin 22.52% SC 22.52% SC 120 400 45.00 10.00 - -
T20 Picoxystrobin 22.52% SC 22.52% SC 150 400 40.00 20.00 - -
T21 Picoxystrobin 22.52% SC 22.52% SC 100 400 45.00 10.00 - -
T22 Untreated Control - - - 50.00 - - -

Table 62: Effect on yield of Fungicidal Compositions of table 61

TN Treatments a.i. % Dose Yield (t/ha) % Yield increase over control E CR
g.a.i. / ha gm - ml /ha

T1 Prothioconazole 20% + Cyazofamid 2.5% + Picoxystrobin 12% SC 20+2.5+12 200+25+120 1000 40.30 207.63 39.99 1.01
T2 Prothioconazole 15% + Cyazofamid 4.5% + Picoxystrobin 15% SC 15+4.5+15 150+45+150 1000 43.10 229.01 42.11 1.02
T3 Prothioconazole 12% + Cyazofamid 6.5% + Picoxystrobin 10% WP 12+6.5+10 120+65+100 1000 43.90 235.11 43.33 1.01
T4 Prothioconazole 25% EC + Cyazofamid 34.5% SC 25% EC + 34.5% SC 200+25 700 + 200 22.00 67.94 30.05 0.73
T5 Prothioconazole 25% EC + Cyazofamid 34.5% SC 25% EC + 34.5% SC 150+45 700 + 200 23.50 79.39 32.30 0.73
T6 Prothioconazole 25% EC + Cyazofamid 34.5% SC 25% EC + 34.5% SC 120+65 700 + 200 24.80 89.31 34.41 0.72
T7 Prothioconazole 25% EC + Picoxystrobin 22.52% SC 25% EC + 22.52% SC 200+120 700 + 400 18.00 37.40 26.81 0.67
T8 Prothioconazole 25% EC + Picoxystrobin 22.52% SC 25% EC + 22.52% SC 150+150 700 + 400 16.20 23.66 26.73 0.61
T9 Prothioconazole 25% EC + Picoxystrobin 22.52% SC 25% EC + 22.52% SC 120+100 700 + 400 17.00 29.77 25.44 0.67
T10 Cyazofamid 34.5% SC + Picoxystrobin 22.52% SC 34.5% SC + 22.52% SC 25+120 200 + 400 16.22 23.82 29.64 0.55
T11 Cyazofamid 34.5% SC + Picoxystrobin 22.52% SC 34.5% SC + 22.52% SC 45+150 200 + 400 17.40 32.82 32.46 0.54
T12 Cyazofamid 34.5% SC + Picoxystrobin 22.52% SC 34.5% SC + 22.52% SC 65+100 200 + 400 18.00 37.40 25.44 0.71
T13 Prothioconazole 25% EC 25% EC 200 700 14.70 12.21 - -
T14 Prothioconazole 25% EC 25% EC 150 700 14.30 9.16 - -
T15 Prothioconazole 25% EC 25% EC 120 700 13.70 4.58 - -
T16 Cyazofamid 34.5% SC 34.5% SC 25 200 18.00 37.40 - -
T17 Cyazofamid 34.5% SC 34.5% SC 45 200 21.00 60.31 - -
T18 Cyazofamid 34.5% SC 34.5% SC 65 200 24.00 83.21 - -
T19 Picoxystrobin 22.52% SC 22.52% SC 120 400 14.20 8.40 - -
T20 Picoxystrobin 22.52% SC 22.52% SC 150 400 14.50 10.69 - -
T21 Picoxystrobin 22.52% SC 22.52% SC 100 400 13.60 3.82 - -
T22 Untreated Control - - - 13.10 - - -

Table 63: Efficacy of Fungicidal Compositions of Prothioconazole + Cyazofamid + Pyraclostrobin in Potato Crop against Late blight

TN Treatments a.i. % Dose Mean after two applications E CR
g. a.i. / ha gm - ml /ha Late blight
PDI% %ROC
T1 Prothioconazole 20% + Cyazofamid 2% + Pyraclostrobin 6% SC 20+2+6 200+20+60 1000 2.42 78.00 43.30 1.80
T2 Prothioconazole 16% + Cyazofamid 4% + Pyraclostrobin 8% SC 16+4+8 160+40+80 1000 3.30 70.00 45.79 1.53
T3 Prothioconazole 12% + Cyazofamid 6% + Pyraclostrobin 6% WP 12+6+6 120+60+60 1000 3.85 65.00 44.11 1.47
T4 Prothioconazole 25% EC + Cyazofamid 34.5% SC 25% EC + 34.5% SC 200+20 700 + 200 7.15 35.00 37.00 0.95
T5 Prothioconazole 25% EC + Cyazofamid 34.5% SC 25% EC + 34.5% SC 160+40 700 + 200 7.21 34.50 38.40 0.90
T6 Prothioconazole 25% EC + Cyazofamid 34.5% SC 25% EC + 34.5% SC 120+60 700 + 200 7.37 33.00 37.90 0.87
T7 Prothioconazole 25% EC + Pyraclostrobin 22% WG 25% EC + 22% WG 200+60 700 + 500 9.24 16.00 19.00 0.84
T8 Prothioconazole 25% EC + Pyraclostrobin 22% WG 25% EC + 22% WG 160+80 700 + 500 9.35 15.00 22.56 0.66
T9 Prothioconazole 25% EC + Pyraclostrobin 22% WG 25% EC + 22% WG 120+60 700 + 500 9.68 12.00 19.00 0.63
T10 Cyazofamid 34.5% SC + Pyraclostrobin 22% WG 34.5% SC + 22% WG 20+60 200 + 500 7.70 30.00 37.00 0.81
T11 Cyazofamid 34.5% SC + Pyraclostrobin 22% WG 34.5% SC + 22% WG 40+80 200 + 500 7.70 30.00 38.40 0.78
T12 Cyazofamid 34.5% SC + Pyraclostrobin 22% WG 34.5% SC + 22% WG 60+60 200 + 500 7.15 35.00 37.90 0.92
T13 Prothioconazole 25% EC 25% EC 200 700 9.90 10.00 - -
T14 Prothioconazole 25% EC 25% EC 160 700 9.68 12.00 - -
T15 Prothioconazole 25% EC 25% EC 120 700 9.90 10.00 - -
T16 Cyazofamid 34.5% SC 34.5% SC 20 200 7.70 30.00 - -
T17 Cyazofamid 34.5% SC 34.5% SC 40 200 7.70 30.00 - -
T18 Cyazofamid 34.5% SC 34.5% SC 60 200 7.59 31.00 - -
T19 Pyraclostrobin 22% WG 22% WG 60 500 9.90 10.00 - -
T20 Pyraclostrobin 22% WG 22% WG 80 500 9.68 12.00 - -
T21 Untreated Control - - - 11.00 - - -

Table 64: Effect on yield of Fungicidal Compositions of table 63
TN Treatments a.i. % Dose Yield (t/ha) % Yield increase over control E CR
g. a.i. / ha gm - ml /ha

T1 Prothioconazole 20% + Cyazofamid 2% + Pyraclostrobin 6% SC 20+2+6 200+20+60 1000 42.30 249.59 39.21 1.08
T2 Prothioconazole 16% + Cyazofamid 4% + Pyraclostrobin 8% SC 16+4+8 160+40+80 1000 42.10 247.93 41.05 1.03
T3 Prothioconazole 12% + Cyazofamid 6% + Pyraclostrobin 6% WP 12+6+6 120+60+60 1000 44.00 263.64 43.11 1.02
T4 Prothioconazole 25% EC + Cyazofamid 34.5% SC 25% EC + 34.5% SC 200+20 700 + 200 26.00 114.88 28.99 0.90
T5 Prothioconazole 25% EC + Cyazofamid 34.5% SC 25% EC + 34.5% SC 160+40 700 + 200 26.00 114.88 30.40 0.86
T6 Prothioconazole 25% EC + Cyazofamid 34.5% SC 25% EC + 34.5% SC 120+60 700 + 200 23.00 90.08 35.28 0.65
T7 Prothioconazole 25% EC + Pyraclostrobin 22% WG 25% EC + 22% WG 200+60 700 + 500 16.20 33.88 25.87 0.63
T8 Prothioconazole 25% EC + Pyraclostrobin 22% WG 25% EC + 22% WG 160+80 700 + 500 17.20 42.15 26.31 0.65
T9 Prothioconazole 25% EC + Pyraclostrobin 22% WG 25% EC + 22% WG 120+60 700 + 500 15.20 25.62 24.14 0.63
T10 Cyazofamid 34.5% SC + Pyraclostrobin 22% WG 34.5% SC + 22% WG 20+60 200 + 500 18.20 50.41 29.81 0.61
T11 Cyazofamid 34.5% SC + Pyraclostrobin 22% WG 34.5% SC + 22% WG 40+80 200 + 500 17.45 44.21 32.24 0.54
T12 Cyazofamid 34.5% SC + Pyraclostrobin 22% WG 34.5% SC + 22% WG 60+60 200 + 500 19.00 57.02 24.14 0.79
T13 Prothioconazole 25% EC 25% EC 200 700 13.40 10.74 - -
T14 Prothioconazole 25% EC 25% EC 160 700 13.00 7.44 - -
T15 Prothioconazole 25% EC 25% EC 120 700 13.70 13.22 - -
T16 Cyazofamid 34.5% SC 34.5% SC 20 200 18.00 48.76 - -
T17 Cyazofamid 34.5% SC 34.5% SC 40 200 20.00 65.29 - -
T18 Cyazofamid 34.5% SC 34.5% SC 60 200 25.00 106.61 - -
T19 Pyraclostrobin 22% WG 22% WG 60 500 14.40 19.01 - -
T20 Pyraclostrobin 22% WG 22% WG 80 500 15.30 26.45 - -
T21 Untreated Control - - - 12.10 - - -

Table 65: Efficacy of Fungicidal Compositions of Prothioconazole + Cyazofamid + Pyraoxystrobin in Potato Crop against Late blight

TN Treatments a.i. % Dose Mean after two applications E CR
g.a.i. / ha gm - ml /ha Late blight
PDI% %ROC
T1 Prothioconazole 25% + Cyazofamid 6.5% + Pyraoxystrobin 6.5% SC 25+6.5+6.5 250+65+65 1000 11.00 80.00 54.51 1.47
T2 Prothioconazole 20% + Cyazofamid 6.5% + Pyraoxystrobin 8% SC 20+2.5+8 200+25+80 1000 12.65 77.00 52.00 1.48
T3 Prothioconazole 15% + Cyazofamid 4.5% + Pyraoxystrobin 4.5% WP 15+4.5+4.5 150+45+45 1000 13.75 75.00 50.25 1.49
T4 Prothioconazole 25% EC + Cyazofamid 34.5% SC 25% EC + 34.5% SC 250+65 700 + 200 31.35 43.00 43.84 0.98
T5 Prothioconazole 25% EC + Cyazofamid 34.5% SC 25% EC + 34.5% SC 200+25 700 + 200 33.55 39.00 40.00 0.98
T6 Prothioconazole 25% EC + Cyazofamid 34.5% SC 25% EC + 34.5% SC 150+45 700 + 200 34.65 37.00 40.06 0.92
T7 Prothioconazole 25% EC + Pyraoxystrobin 20% SC 25% EC + 20% SC 250+65 700 + 500 36.85 33.00 36.82 0.90
T8 Prothioconazole 25% EC + Pyraoxystrobin 20% SC 25% EC + 20% SC 200+80 700 + 500 37.40 32.00 36.00 0.89
T9 Prothioconazole 25% EC + Pyraoxystrobin 20% SC 25% EC + 20% SC 150+45 700 + 500 38.50 30.00 32.77 0.92
T10 Cyazofamid 34.5% SC + Pyraoxystrobin 20% SC 34.5% SC + 20% SC 250+65 200 + 500 34.10 38.00 41.68 0.91
T11 Cyazofamid 34.5% SC + Pyraoxystrobin 20% SC 34.5% SC + 20% SC 200+25 200 + 500 35.20 36.00 40.00 0.90
T12 Cyazofamid 34.5% S + Pyraoxystrobin 20% SC 34.5% SC + 20% SC 150+45 200 + 500 35.75 35.00 38.58 0.91
T13 Prothioconazole 25% EC 25% EC 250 700 42.90 22.00 - -
T14 Prothioconazole 25% EC 25% EC 200 700 44.00 20.00 - -
T15 Prothioconazole 25% EC 25% EC 150 700 44.55 19.00 - -
T16 Cyazofamid 34.5% SC 34.5% SC 65 200 39.60 28.00 - -
T17 Cyazofamid 34.5% SC 34.5% SC 25 200 41.25 25.00 - -
T18 Cyazofamid 34.5% SC 34.5% SC 45 200 40.70 26.00 - -
T19 Pyraoxystrobin 20% SC 20% SC 65 500 44.55 19.00 - -
T20 Pyraoxystrobin 20% SC 20% SC 80 500 44.00 20.00 - -
T21 Pyraoxystrobin 20% SC 20% SC 45 500 45.65 17.00 - -
T22 Untreated Control - - 55.00 - - -

Table 66: Effect on yield of Fungicidal Compositions of table 65
TN Treatments a.i. % Dose Yield (t/ha) % Yield increase over control E CR
g. a.i. / ha gm - ml /ha

T1 Prothioconazole 25% + Cyazofamid 6.5% + Pyraoxystrobin 6.5% SC 25+6.5+6.5 250+65+65 1000 39.00 254.55 35.55 1.10
T2 Prothioconazole 20% + Cyazofamid 6.5% + Pyraoxystrobin 8% SC 20+2.5+8 200+25+80 1000 38.00 245.45 35.49 1.07
T3 Prothioconazole 15% + Cyazofamid 4.5% + Pyraoxystrobin 4.5% WP 15+4.5+4.5 150+45+45 1000 37.00 236.36 34.90 1.06
T4 Prothioconazole 25% EC + Cyazofamid 34.5% SC 25% EC + 34.5% SC 250+65 700+ 200 24.00 118.18 24.67 0.97
T5 Prothioconazole 25% EC + Cyazofamid 34.5% SC 25% EC + 34.5% SC 200+25 700+ 200 22.00 100.00 24.23 0.91
T6 Prothioconazole 25% EC + Cyazofamid 34.5% SC 25% EC + 34.5% SC 150+45 700+ 200 19.00 72.73 24.34 0.78
T7 Prothioconazole 25% EC + Pyraoxystrobin 20% SC 25% EC + 20% SC 250+65 700+ 500 17.00 54.55 24.71 0.69
T8 Prothioconazole 25% EC + Pyraoxystrobin 20% SC 25% EC + 20% SC 200+80 700+ 500 17.40 58.18 25.08 0.69
T9 Prothioconazole 25% EC + Pyraoxystrobin 20% SC 25% EC + 20% SC 150+45 700+ 500 16.44 49.45 23.60 0.70
T10 Cyazofamid 34.5% SC + Pyraoxystrobin 20% SC 34.5% SC + 20% SC 250+65 200+ 500 18.30 66.36 26.76 0.68
T11 Cyazofamid 34.5% SC + Pyraoxystrobin 20% SC 34.5% SC + 20% SC 200+25 200+ 500 17.45 58.64 26.69 0.65
T12 Cyazofamid 34.5% SC + Pyraoxystrobin 20% SC 34.5% SC + 20% SC 150+45 200+ 500 16.22 47.45 23.60 0.69
T13 Prothioconazole 25% EC 25% EC 250 700 12.00 9.09 - -
T14 Prothioconazole 25% EC 25% EC 200 700 12.00 9.09 - -
T15 Prothioconazole 25% EC 25% EC 150 700 11.20 1.82 - -
T16 Cyazofamid 34.5% SC 34.5% SC 65 200 14.40 30.91 - -
T17 Cyazofamid 34.5% SC 34.5% SC 25 200 13.90 26.36 - -
T18 Cyazofamid 34.5% SC 34.5% SC 45 200 14.80 34.55 - -
T19 Pyraoxystrobin 20% SC 20% SC 65 500 14.44 31.27 - -
T20 Pyraoxystrobin 20% SC 20% SC 80 500 14.86 35.09 - -
T21 Pyraoxystrobin 20% SC 20% SC 45 500 13.96 26.91 - -
T22 Untreated Control - - - 11.00 - - -

Table 67: Efficacy of Fungicidal Compositions of Prothioconazole + Cyazofamid + Trifloxystrobin in Potato Crop against Late blight

TN Treatments a.i. % Dose Mean after two applications E CR
g. a.i. / ha gm - ml /ha Late blight
PDI% %ROC
T1 Prothioconazole 20% + Cyazofamid 3% + Trifloxystrobin 3% SC 20+3+3 200+30+30 1000 13.50 75.00 46.45 1.61
T2 Prothioconazole 15% + Cyazofamid 5% + Trifloxystrobin 2% SC 15+5+2 150+50+20 1000 21.60 60.00 45.79 1.31
T3 Prothioconazole 18% + Cyazofamid 7% + Trifloxystrobin 1% SC 18+7+1 180+70+10 1000 18.90 65.00 44.11 1.47
T4 Prothioconazole 25% EC + Cyazofamid 34.5% SC 25% EC + 34.5% SC 200+30 700 + 200 35.64 34.00 37.00 0.92
T5 Prothioconazole 25% EC + Cyazofamid 34.5% SC 25% EC + 34.5% SC 150+50 700 + 200 37.80 30.00 38.40 0.78
T6 Prothioconazole 25% EC + Cyazofamid 34.5% SC 25% EC + 34.5% SC 180+70 700 + 200 35.10 35.00 37.90 0.92
T7 Prothioconazole 25% EC + Trifloxystrobin 42.6% SC 25% EC + 42.6% SC 200+30 700 + 253 43.20 20.00 23.50 0.85
T8 Prothioconazole 25% EC + Trifloxystrobin 42.6% SC 25% EC + 42.6% SC 150+20 700 + 253 48.06 11.00 22.56 0.49
T9 Prothioconazole 25% EC + Trifloxystrobin 42.6% SC 25% EC + 42.6% SC 180+10 700 + 253 45.90 15.00 19.00 0.79
T10 Cyazofamid 34.5% SC + Trifloxystrobin 42.6% SC 34.5% SC + 42.6% SC 30+30 200 + 253 37.80 30.00 40.50 0.74
T11 Cyazofamid 34.5% SC + Trifloxystrobin 42.6% SC 34.5% SC + 42.6% SC 50+20 200 + 253 37.80 30.00 38.40 0.78
T12 Cyazofamid 34.5% SC + Trifloxystrobin 42.6% SC 34.5% SC + 42.6% SC 70+10 200 + 253 35.10 35.00 37.90 0.92
T13 Prothioconazole 25% EC 25% EC 200 700 48.60 10.00 - -
T14 Prothioconazole 25% EC 25% EC 150 700 47.52 12.00 - -
T15 Prothioconazole 25% EC 25% EC 180 700 48.60 10.00 - -
T16 Cyazofamid 34.5% SC 34.5% SC 30 200 37.80 30.00 - -
T17 Cyazofamid 34.5% SC 34.5% SC 50 200 37.80 30.00 - -
T18 Cyazofamid 34.5% SC 34.5% SC 70 200 37.26 31.00 - -
T19 Trifloxystrobin 42.6% SC 42.6% SC 30 253 45.90 15.00 - -
T20 Trifloxystrobin 42.6% SC 42.6% SC 20 253 47.52 12.00 - -
T21 Trifloxystrobin 42.6% SC 42.6% SC 10 253 48.60 10.00 - -
T22 Untreated Control - - - 54.00 - - -

Table 68: Effect on yield of Fungicidal Compositions of table 67
TN Treatments a.i. % Dose Yield (t/ha) % Yield increase over control E CR
g. a.i. / ha gm - ml /ha

T1 Prothioconazole 2 % + Cyazofamid 3% + Trifloxystrobin 3% SC 20+3+3 200+30+30 1000 41.00 228.00 40.06 1.02
T2 Prothioconazole 15% + Cyazofamid 5% + Trifloxystrobin 2% SC 15+5+2 150+50+20 1000 41.00 228.00 40.49 1.01
T3 Prothioconazole 18% + Cyazofamid 7% + Trifloxystrobin 1% SC 18+7+1 180+70+10 1000 44.20 253.60 43.53 1.02
T4 Prothioconazole 25% EC + Cyazofamid 34.5% SC 25% EC + 34.5% SC 200+30 700 + 200 25.00 100.00 29.89 0.84
T5 Prothioconazole 25% EC + Cyazofamid 34.5% SC 25% EC + 34.5% SC 150+50 700 + 200 26.00 108.00 30.72 0.85
T6 Prothioconazole 25% EC + Cyazofamid 34.5% SC 25% EC + 34.5% SC 180+70 700 + 200 30.00 140.00 34.64 0.87
T7 Prothioconazole 25% EC + Trifloxystrobin 42.6% SC 25% EC + 42.6% SC 200+30 700 + 253 18.20 45.60 26.90 0.68
T8 Prothioconazole 25% EC + Trifloxystrobin 42.6% SC 25% EC + 42.6% SC 150+20 700 + 253 16.50 32.00 25.61 0.64
T9 Prothioconazole 25% EC + Trifloxystrobin 42.6% SC 25% EC + 42.6% SC 180+10 700 + 253 17.50 40.00 25.70 0.68
T10 Cyazofamid 34.5% SC + Trifloxystrobin 42.6% SC 34.5% SC + 42.6% SC 30+30 200 + 253 16.30 30.40 29.89 0.55
T11 Cyazofamid 34.5% SC + Trifloxystrobin 42.6% SC 34.5% SC + 42.6% SC 50+20 200 + 253 17.50 40.00 31.28 0.56
T12 Cyazofamid 34.5% SC + Trifloxystrobin 42.6% SC 34.5% SC + 42.6% SC 70+10 200 + 253 18.30 46.40 25.70 0.71
T13 Prothioconazole 25% EC 25% EC 200 700 14.50 16.00 - -
T14 Prothioconazole 25% EC 25% EC 150 700 13.40 7.20 - -
T15 Prothioconazole 25% EC 25% EC 180 700 14.00 12.00 - -
T16 Cyazofamid 34.5% SC 34.5% SC 30 200 18.00 44.00 - -
T17 Cyazofamid 34.5% SC 34.5% SC 50 200 20.00 60.00 - -
T18 Cyazofamid 34.5% SC 34.5% SC 70 200 24.00 92.00 - -
T19 Trifloxystrobin 42.6% SC 42.6% SC 30 253 14.50 16.00 - -
T20 Trifloxystrobin 42.6% SC 42.6% SC 20 253 14.10 12.80 - -
T21 Trifloxystrobin 42.6% SC 42.6% SC 10 253 13.60 8.80 - -
T22 Untreated Control - - - 12.50 - - -

Table 69: Efficacy of Fungicidal Compositions of Prothioconazole + Cymoxanil + Azoxystrobin in Chilli Crop against Die back

TN Treatments a.i. % Dose Mean after two applications E CR
g.a.i. / ha gm - ml /ha Die back
PDI% %ROC
T1 Prothioconazole 20% + Cymoxanil 6%+ Azoxystrobin 10% SC 20+6+10 200+60+100 1000 7.36 84.00 56.04 1.50
T2 Prothioconazole 16% + Cymoxanil 8%+ Azoxystrobin 8% SC 16+8+8 160+80+80 1000 8.74 81.00 54.62 1.48
T3 Prothioconazole 10% + Cymoxanil 5%+ Azoxystrobin 5% WP 10+5+5 100+50+50 1000 10.12 78.00 51.72 1.51
T4 Prothioconazole 25% EC + Cymoxanil 50% WP 25% EC + 50% WP 200+60 700 + 120 29.90 35.00 38.08 0.92
T5 Prothioconazole 25% EC + Cymoxanil 50% WP 25% EC + 50% WP 160+80 700 + 160 30.82 33.00 37.84 0.87
T6 Prothioconazole 25% EC + Cymoxanil 50% WP 25% EC + 50% WP 100+50 700 + 100 31.28 32.00 34.75 0.92
T7 Prothioconazole 25% EC + Azoxystrobin 23% SC 25% EC + 23% SC 200+100 700 + 500 25.76 44.00 48.88 0.90
T8 Prothioconazole 25% EC + Azoxystrobin 23% SC 25% EC + 23% SC 160+80 700 + 500 26.68 42.00 45.98 0.91
T9 Prothioconazole 25% EC + Azoxystrobin 23% SC 25% EC + 23% SC 100+50 700 + 500 27.14 41.00 44.50 0.92
T10 Cymoxanil 50% WP + Azoxystrobin 23% SC 50% WP + 23% SC 60+100 120 + 500 31.28 32.00 38.94 0.82
T11 Cymoxanil 50% WP + Azoxystrobin 23% SC 50% WP + 23% SC 80+80 160 + 500 31.28 32.00 38.68 0.83
T12 Cymoxanil 50% WP + Azoxystrobin 23% SC 50% WP + 23% SC 50+50 100 + 500 31.74 31.00 35.62 0.87
T13 Prothioconazole 25% EC 25% EC 200 700 33.12 28.00 - -
T14 Prothioconazole 25% EC 25% EC 160 700 34.04 26.00 - -
T15 Prothioconazole 25% EC 25% EC 100 700 34.50 25.00 - -
T16 Cymoxanil 50% WP 50% WP 60 120 39.56 14.00 - -
T17 Cymoxanil 50% WP 50% WP 80 160 38.64 16.00 - -
T18 Cymoxanil 50% WP 50% WP 50 100 40.02 13.00 - -
T19 Azoxystrobin 23% SC 23% SC 100 500 32.66 29.00 - -
T20 Azoxystrobin 23% SC 23% SC 80 500 33.58 27.00 - -
T21 Azoxystrobin 23% SC 23% SC 50 500 34.04 26.00 - -
T22 Untreated Control - - - 46.00 - - -

Table 70: Effect on yield of Fungicidal Compositions of table 69
TN Treatments a.i. % Dose Yield (t/ha) % Yield increase over control E CR
g.a.i. / ha gm - ml /ha

T1 Prothioconazole 20% + Cymoxanil 6% + Azoxystrobin 10% SC 20+6+10 200+60+100 1000 12.20 237.02 11.72 1.04
T2 Prothioconazole 16% + Cymoxanil 8% + Azoxystrobin 8% SC 16+8+8 160+80+80 1000 11.12 207.18 11.35 0.98
T3 Prothioconazole 10% + Cymoxanil 5% + Azoxystrobin 5% WP 10+5+5 100+50+50 1000 12.98 258.56 12.73 1.02
T4 Prothioconazole 25% EC + Cymoxanil 50% WP 25% EC + 50% WP 200+60 700 + 120 5.50 51.93 7.85 0.70
T5 Prothioconazole 25% EC + Cymoxanil 50% WP 25% EC + 50% WP 160+80 700 + 160 5.80 60.22 7.17 0.81
T6 Prothioconazole 25% EC + Cymoxanil 50% WP 25% EC + 50% WP 100+50 700 + 100 6.20 71.27 8.04 0.77
T7 Prothioconazole 25% EC + Azoxystrobin 23% SC 25% EC + 23% SC 200+100 700 + 500 7.60 109.94 8.89 0.85
T8 Prothioconazole 25% EC + Azoxystrobin 23% SC 25% EC + 23% SC 160+80 700 + 500 7.90 118.23 8.51 0.93
T9 Prothioconazole 25% EC + Azoxystrobin 23% SC 25% EC + 23% SC 100+50 700 + 500 7.80 115.47 9.94 0.78
T10 Cymoxanil 50% WP + Azoxystrobin 23% SC 50% WP + 23% SC 60+100 120 + 500 6.00 65.75 7.17 0.84
T11 Cymoxanil 50% WP + Azoxystrobin 23% SC 50% WP + 23% SC 80+80 160 + 500 5.70 57.46 7.46 0.76
T12 Cymoxanil 50% WP + Azoxystrobin 23% SC 50% WP + 23% SC 50+50 100 + 500 5.30 46.41 9.94 0.53
T13 Prothioconazole 25% EC 25% EC 200 700 4.90 35.36 - -
T14 Prothioconazole 25% EC 25% EC 160 700 4.20 16.02 - -
T15 Prothioconazole 25% EC 25% EC 100 700 5.10 40.88 - -
T16 Cymoxanil 50% WP 50% WP 60 120 3.10 -14.36 - -
T17 Cymoxanil 50% WP 50% WP 80 160 3.10 -14.36 - -
T18 Cymoxanil 50% WP 50% WP 50 100 3.10 -14.36 - -
T19 Azoxystrobin 23% SC 23% SC 100 500 4.20 16.02 - -
T20 Azoxystrobin 23% SC 23% SC 80 500 4.50 24.31 - -
T21 Azoxystrobin 23% SC 23% SC 50 500 5.10 40.88 - -
T22 Untreated Control - - - 3.62 - - -

Table 71: Efficacy of Fungicidal Compositions of Prothioconazole + Cymoxanil + Fenaminstrobin in Chilli Crop against Die back

TN Treatments a.i. % Dose Mean after two applications E CR
g.a.i. / ha gm - ml /ha Die back
PDI% %ROC
T1 Prothioconazole 20% + Cymoxanil 8% + Fenaminstrobin 9% SC 20+8+9 200+80+90 1000 8.64 82.00 54.08 1.52
T2 Prothioconazole 15% + Cymoxanil 6% + Fenaminstrobin 5% SC 15+6+5 150+60+50 1000 11.04 77.00 49.76 1.55
T3 Prothioconazole 20% + Cymoxanil 5% + Fenaminstrobin 7% WP 20+5+7 200+50+70 1000 9.60 80.00 51.18 1.56
T4 Prothioconazole 25% EC + Cymoxanil 50% WP 25% EC + 50% WP 200+80 700 + 160 31.68 34.00 37.95 0.90
T5 Prothioconazole 25% EC + Cymoxanil 50% WP 25% EC + 50% WP 150+60 700 + 120 32.64 32.00 34.75 0.92
T6 Prothioconazole 25% EC + Cymoxanil 50% WP 25% EC + 50% WP 200+50 700 + 100 31.68 34.00 35.76 0.95
T7 Prothioconazole 25% EC + Fenaminstrobin 20% SC 25% EC + 20% SC 200 +90 700 + 500 27.36 43.00 45.98 0.94
T8 Prothioconazole 25% EC + Fenaminstrobin 20% SC 25% EC + 20% SC 150 +50 700 + 500 28.80 40.00 42.25 0.95
T9 Prothioconazole 25% EC + Fenaminstrobin 20% SC 25% EC + 20% SC 200 +70 700 + 500 27.36 43.00 44.52 0.97
T10 Cymoxanil 50% WP + Fenaminstrobin 20% SC 50% WP + 20% SC 80+90 160 + 500 32.16 33.00 37.10 0.89
T11 Cymoxanil 50% WP + Fenaminstrobin 20% SC 50% WP + 20% SC 60+50 120 + 500 33.60 30.00 33.01 0.91
T12 Cymoxanil 50% WP + Fenaminstrobin 20% SC 50% WP + 20% SC 50+70 100 + 500 33.60 30.00 33.12 0.91
T13 Prothioconazole 25% EC 25% EC 200 700 35.04 27.00 - -
T14 Prothioconazole 25% EC 25% EC 150 700 36.00 25.00 - -
T15 Prothioconazole 25% EC 25% EC 200 700 35.04 27.00 - -
T16 Cymoxanil 50% WP 50% WP 80 160 40.80 15.00 - -
T17 Cymoxanil 50% WP 50% WP 60 120 41.76 13.00 - -
T18 Cymoxanil 50% WP 50% WP 50 100 42.24 12.00 - -
T19 Fenaminstrobin 20% SC 20% SC 90 500 35.52 26.00 - -
T20 Fenaminstrobin 20% SC 20% SC 50 500 36.96 23.00 - -
T21 Fenaminstrobin 20% SC 20% SC 70 500 36.48 24.00 - -
T22 Untreated Control - - - 48.00 - - -

Table 72: Effect on yield of Fungicidal Compositions of table 71
TN Treatments a.i. % Dose Yield (t/ha) % Yield increase over control E CR
g.a.i. / ha gm - ml /ha

T1 Prothioconazole 20% + Cymoxanil 8% + Fenaminstrobin 9% SC 20+8+9 200+80+90 1000 12.80 212.20 11.74 1.09
T2 Prothioconazole 15% + Cymoxanil 6% + Fenaminstrobin 5% SC 15+6+5 150+60+50 1000 11.80 187.80 11.26 1.05
T3 Prothioconazole 20% + Cymoxanil 5% + Fenaminstrobin 7% WP 20+5+7 200+50+70 1000 14.00 241.46 12.73 1.10
T4 Prothioconazole 25% EC + Cymoxanil 50% WP 25% EC + 50% WP 200+80 700 + 160 6.90 68.29 7.87 0.88
T5 Prothioconazole 25% EC + Cymoxanil 50% WP 25% EC + 50% WP 150+60 700 + 120 6.60 60.98 7.07 0.93
T6 Prothioconazole 25% EC + Cymoxanil 50% WP 25% EC + 50% WP 200+50 700 + 100 7.00 70.73 8.04 0.87
T7 Prothioconazole 25% EC + Fenaminstrobin 20% SC 25% EC + 20% SC 200 +90 700 + 500 7.86 91.71 8.89 0.88
T8 Prothioconazole 25% EC + Fenaminstrobin 20% SC 25% EC + 20% SC 150 +50 700 + 500 7.50 82.93 8.51 0.88
T9 Prothioconazole 25% EC + Fenaminstrobin 20% SC 25% EC + 20% SC 200 +70 700 + 500 8.00 95.12 9.94 0.80
T10 Cymoxanil 50% WP + Fenaminstrobin 20% SC 50% WP + 20% SC 80+90 160 + 500 6.80 65.85 7.19 0.95
T11 Cymoxanil 50% WP + Fenaminstrobin 20% SC 50% WP + 20% SC 60+50 120 + 500 6.90 68.29 7.37 0.94
T12 Cymoxanil 50% WP + Fenaminstrobin 20% SC 50% WP + 20% SC 50+70 100 + 500 7.25 76.83 9.94 0.73
T13 Prothioconazole 25% EC 25% EC 200 700 4.90 19.51 - -
T14 Prothioconazole 25% EC 25% EC 150 700 4.20 2.44 - -
T15 Prothioconazole 25% EC 25% EC 200 700 5.10 24.39 - -
T16 Cymoxanil 50% WP 50% WP 80 160 3.12 23.90 - -
T17 Cymoxanil 50% WP 50% WP 60 120 3.00 26.83 - -
T18 Cymoxanil 50% WP 50% WP 50 100 3.10 24.39 - -
T19 Fenaminstrobin 20% SC 20% SC 90 500 4.20 2.44 - -
T20 Fenaminstrobin 20% SC 20% SC 50 500 4.50 9.76 - -
T21 Fenaminstrobin 20% SC 20% SC 70 500 5.10 24.39 - -
T22 Untreated Control - - - 4.10 - - -

Table 73: Efficacy of Fungicidal Compositions of Prothioconazole + Cymoxanil + Picoxystrobin in Chilli Crop against Die back

TN Treatments a.i. % Dose Mean after two applications E CR
g. a.i. / ha gm - ml /ha Die back
PDI% %ROC
T1 Prothioconazole 20% + Cymoxanil 6% + Picoxystrobin 15% SC 20+6+15 200+60+150 1000 12.00 75.00 52.70 1.42
T2 Prothioconazole 15% + Cymoxanil 8% + Picoxystrobin 18% SC 15+8+18 150+80+180 1000 13.44 72.00 52.71 1.37
T3 Prothioconazole 12% + Cymoxanil 10% + Picoxystrobin 10% WP 12+10+10 120+100+100 1000 14.40 70.00 51.16 1.37
T4 Prothioconazole 25% EC + Cymoxanil 50% WP 25% EC + 50% WP 200+60 700 + 120 32.16 33.00 35.20 0.94
T5 Prothioconazole 25% EC + Cymoxanil 50% WP 25% EC + 50% WP 150+80 700 + 160 32.64 32.00 33.40 0.96
T6 Prothioconazole 25% EC + Cymoxanil 50% WP 25% EC + 50% WP 120+100 700 + 200 33.60 30.00 34.00 0.88
T7 Prothioconazole 25% EC + Picoxystrobin 22.52% SC 25% EC + 22.52% SC 200 +150 700 + 400 27.84 42.00 47.44 0.89
T8 Prothioconazole 25% EC + Picoxystrobin 22.52% SC 25% EC + 22.52% SC 150 +180 700 + 400 27.84 42.00 47.46 0.88
T9 Prothioconazole 25% EC + Picoxystrobin 22.52% SC 25% EC + 22.52% SC 120+100 700 + 400 28.32 41.00 44.50 0.92
T10 Cymoxanil 50% WP + Picoxystrobin 22.52% SC 50% WP + 22.52% SC 60+150 120 + 400 32.64 32.00 34.30 0.93
T11 Cymoxanil 50% WP + Picoxystrobin 22.52% SC 50% WP + 22.52% SC 80+180 160 + 400 32.64 32.00 36.10 0.89
T12 Cymoxanil 50% WP + Picoxystrobin 22.52% SC 50% WP + 22.52% SC 100+100 200 + 400 33.60 30.00 34.88 0.86
T13 Prothioconazole 25% EC 25% EC 200 700 34.56 28.00 - -
T14 Prothioconazole 25% EC 25% EC 150 700 35.52 26.00 - -
T15 Prothioconazole 25% EC 25% EC 120 700 36.00 25.00 - -
T16 Cymoxanil 50% WP 50% WP 60 120 43.20 10.00 - -
T17 Cymoxanil 50% WP 50% WP 80 160 43.20 10.00 - -
T18 Cymoxanil 50% WP 50% WP 100 200 42.24 12.00 - -
T19 Picoxystrobin 22.52% SC 22.52% SC 150 400 35.04 27.00 - -
T20 Picoxystrobin 22.52% SC 22.52% SC 180 400 34.08 29.00 - -
T21 Picoxystrobin 22.52% SC 22.52% SC 100 400 35.52 26.00 - -
T22 Untreated Control - - - 48.00 - - -

Table 74: Effect on yield of Fungicidal Compositions of table 73
TN Treatments a.i. % Dose Yield (t/ha) % Yield increase over control E CR
g. a.i. / ha gm - ml /ha

T1 Prothioconazole 20% + Cymoxanil 6% + Picoxystrobin 15% SC 20+6+15 200+60+150 1000 14.20 259.49 11.74 1.21
T2 Prothioconazole 15% + Cymoxanil 8% + Picoxystrobin 18% SC 15+8+18 150+80+180 1000 13.00 229.11 11.26 1.15
T3 Prothioconazole 12 % + Cymoxanil 10% + Picoxystrobin 10% WP 12+10+10 120+100+100 1000 13.00 229.11 12.73 1.02
T4 Prothioconazole 25% EC + Cymoxanil 50% WP 25% EC + 50% WP 200+60 700+ 120 7.00 77.22 7.87 0.89
T5 Prothioconazole 25% EC + Cymoxanil 50% WP 25% EC + 50% WP 150+80 700+ 160 6.60 67.09 7.07 0.93
T6 Prothioconazole 25% EC + Cymoxanil 50% WP 25% EC + 50% WP 120+100 700+ 200 7.00 77.22 8.04 0.87
T7 Prothioconazole 25% EC + Picoxystrobin 22.52% SC 25% EC + 22.52% SC 200 +150 700+ 400 8.00 102.53 8.89 0.90
T8 Prothioconazole 25% EC + Picoxystrobin 22.52% SC 25% EC + 22.52% SC 150 +180 700+ 400 7.50 89.87 8.51 0.88
T9 Prothioconazole 25% EC + Picoxystrobin 22.52% SC 25% EC + 22.52% SC 120+100 700+ 400 7.00 77.22 9.94 0.70
T10 Cymoxanil 50% WP + Picoxystrobin 22.52% SC 50% WP + 22.52% SC 60+150 120+ 400 6.80 72.15 7.19 0.95
T11 Cymoxanil 50% WP + Picoxystrobin 22.52% SC 50% WP + 22.52% SC 80+180 160+ 400 6.90 74.68 7.37 0.94
T12 Cymoxanil 50% WP + Picoxystrobin 22.52% SC 50% WP + 22.52% SC 100+100 200+ 400 7.50 89.87 9.94 0.75
T13 Prothioconazole 25% EC 25% EC 200 700 4.90 24.05 - -
T14 Prothioconazole 25% EC 25% EC 150 700 4.20 6.33 - -
T15 Prothioconazole 25% EC 25% EC 120 700 5.10 29.11 - -
T16 Cymoxanil 50% WP 50% WP 60 120 3.12 21.01 - -
T17 Cymoxanil 50% WP 50% WP 80 160 3.00 24.05 - -
T18 Cymoxanil 50% WP 50% WP 100 200 3.10 21.52 - -
T19 Picoxystrobin 22.52% SC 22.52% SC 150 400 4.20 6.33 - -
T20 Picoxystrobin 22.52% SC 22.52% SC 180 400 4.50 13.92 - -
T21 Picoxystrobin 22.52% SC 22.52% SC 100 400 5.10 29.11 - -
T22 Untreated Control - - - 3.95 - - -

Table 75: Efficacy of Fungicidal Compositions of Prothioconazole + Cymoxanil + Pyraclostrobin in Chilli Crop against Die back

TN Treatments a.i. % Dose Mean after two applications E CR
g. a.i. / ha gm - ml /ha Die back
PDI% %ROC
T1 Prothioconazole 20% + Cymoxanil 6% + Pyraclostrobin 6% SC 20+6+6 200+60+60 1000 9.40 80.00 51.85 1.54
T2 Prothioconazole 16% + Cymoxanil 8% + Pyraclostrobin 8% SC 16+8+8 160+80+80 1000 9.40 80.00 52.91 1.51
T3 Prothioconazole 12% + Cymoxanil 6% + Pyraclostrobin 6% WP 12+6+6 120+60+60 1000 10.34 78.00 48.21 1.62
T4 Prothioconazole 25% EC + Cymoxanil 50% WP 25% EC + 50% WP 200+60 700 + 120 30.55 35.00 36.64 0.96
T5 Prothioconazole 25% EC + Cymoxanil 50% WP 25% EC + 50% WP 160+80 700 + 160 31.02 34.00 36.36 0.94
T6 Prothioconazole 25% EC + Cymoxanil 50% WP 25% EC + 50% WP 120+60 700 + 120 31.96 32.00 33.12 0.97
T7 Prothioconazole 25% EC + Pyraclostrobin 20% WG 25% EC + 20% WG 200+60 700 + 500 26.32 44.00 45.28 0.97
T8 Prothioconazole 25% EC + Pyraclostrobin 20% WG 25% EC + 20% WG 160+80 700 + 500 27.26 42.00 45.24 0.93
T9 Prothioconazole 25% EC + Pyraclostrobin 20% WG 25% EC + 20% WG 120+60 700 + 500 28.20 40.00 42.24 0.95
T10 Cymoxanil 50% WP + Pyraclostrobin 20% WG 50% WP + 20% WG 60+60 120 + 500 31.96 32.00 33.12 0.97
T11 Cymoxanil 50% WP + Pyraclostrobin 20% WG 50% WP + 20% WG 80+80 160 + 500 31.02 34.00 36.36 0.94
T12 Prothioconazole 25% EC 25% EC 200 700 33.84 28.00 - -
T13 Prothioconazole 25% EC 25% EC 160 700 34.78 26.00 - -
T14 Prothioconazole 25% EC 25% EC 120 700 35.72 24.00 - -
T15 Cymoxanil 50% WP 50% WP 60 120 41.36 12.00 - -
T16 Cymoxanil 50% WP 50% WP 80 160 40.42 14.00 - -
T17 Pyraclostrobin 20% WG 20% WG 60 500 35.72 24.00 - -
T18 Pyraclostrobin 20% WG 20% WG 80 500 34.78 26.00 - -
T19 Untreated Control - - - 47.00 - - -

Table 76: Effect on yield of Fungicidal Compositions of table 75
TN Treatments a.i. % Dose Yield (t/ha) % Yield increase over control E CR
g.a.i. / ha gm - ml /ha

T1 Prothioconazole 20% + Cymoxanil 6% + Pyraclostrobin 6% SC 20+6+6 200+60+60 1000 12.10 303.33 9.01 1.34
T2 Prothioconazole 16% + Cymoxanil 8% + Pyraclostrobin 8% SC 16+8+8 160+80+80 1000 11.00 266.67 6.98 1.58
T3 Prothioconazole 12% + Cymoxanil 6% + Pyraclostrobin 6% WP 12+6+6 120+60+60 1000 10.00 233.33 7.00 1.43
T4 Prothioconazole 25% EC + Cymoxanil 50% WP 25% EC + 50% WP 200+60 700 + 120 7.00 133.33 6.20 1.13
T5 Prothioconazole 25% EC + Cymoxanil 50% WP 25% EC + 50% WP 160+80 700 + 160 6.60 120.00 6.98 0.95
T6 Prothioconazole 25% EC + Cymoxanil 50% WP 25% EC + 50% WP 120+60 700 + 120 6.50 116.67 7.00 0.93
T7 Prothioconazole 25% EC + Pyraclostrobin 20% WG 25% EC + 20% WG 200+60 700 + 500 6.00 100.00 6.01 1.00
T8 Prothioconazole 25% EC + Pyraclostrobin 20% WG 25% EC + 20% WG 160+80 700 + 500 3.00 0.00 3.10 0.97
T9 Prothioconazole 25% EC + Pyraclostrobin 20% WG 25% EC + 20% WG 120+60 700 + 500 3.00 0.00 3.12 0.96
T10 Cymoxanil 50% WP + Pyraclostrobin 20% WG 50% WP + 20% WG 60+60 120 + 500 4.00 33.33 6.10 0.66
T11 Cymoxanil 50% WP + Pyraclostrobin 20% WG 50% WP + 20% WG 80+80 160 + 500 3.80 26.67 4.00 0.95
T12 Prothioconazole 25% EC 25% EC 200 700 3.20 6.67 - -
T13 Prothioconazole 25% EC 25% EC 160 700 3.10 3.33 - -
T14 Prothioconazole 25% EC 25% EC 120 700 3.10 3.33 - -
T15 Cymoxanil 50% WP 50% WP 60 120 3.12 4.00 - -
T16 Cymoxanil 50% WP 50% WP 80 160 3.20 6.67 - -
T17 Pyraclostrobin 20% WG 20% WG 60 500 4.00 33.33 - -
T18 Pyraclostrobin 20% WG 20% WG 80 500 4.00 33.33 - -
T19 Untreated Control - - - 3.00 - - -

Table 77: Efficacy of Fungicidal Compositions of Prothioconazole + Cymoxanil + Pyraoxystrobin in Chilli Crop against Die back

TN Treatments a.i. % Dose Mean after two applications E CR
g.a.i. / ha gm - ml /ha Die back
PDI% %ROC
T1 Prothioconazole 25% + Cymoxanil 7.5% + Pyraoxystrobin 6.5% SC 25+7.5+6.5 250+75+65 1000 9.60 80.00 52.84 1.51
T2 Prothioconazole 20% + Cymoxanil 9% + Pyraoxystrobin 8% SC 20+9+8 200+90+80 1000 10.56 78.00 53.94 1.45
T3 Prothioconazole 15% + Cymoxanil 5.5% + Pyraoxystrobin 5.5% WP 15+5.5+5.5 150+55+55 1000 12.00 75.00 47.82 1.57
T4 Prothioconazole 25% EC + Cymoxanil 50% WP 25% EC + 50% WP 250+75 700 + 150 30.24 37.00 37.95 0.97
T5 Prothioconazole 25% EC + Cymoxanil 50% WP 25% EC + 50% WP 200+90 700 + 180 31.20 35.00 37.75 0.93
T6 Prothioconazole 25% EC + Cymoxanil 50% WP 25% EC + 50% WP 150+55 700 + 110 32.64 32.00 32.24 0.99
T7 Prothioconazole 25% EC + Pyraoxystrobin 20% SC 25% EC + 20% SC 250 +65 700 + 500 26.88 44.00 44.52 0.99
T8 Prothioconazole 25% EC + Pyraoxystrobin 20% SC 25% EC + 20% SC 200 +80 700 + 500 27.36 43.00 44.50 0.97
T9 Prothioconazole 25% EC + Pyraoxystrobin 20% SC 25% EC + 20% SC 150+55 700 + 500 28.80 40.00 40.71 0.98
T10 Cymoxanil 50% WP + Pyraoxystrobin 20% SC 50% WP + 20% SC 75+65 150 + 500 31.68 34.00 35.40 0.96
T11 Cymoxanil 50% WP + Pyraoxystrobin 20% SC 50% WP + 20% SC 90+80 180 + 500 30.72 36.00 38.58 0.93
T12 Cymoxanil 50% WP + Pyraoxystrobin 20% SC 50% WP + 20% SC 55+55 110 + 500 33.12 31.00 32.24 0.96
T13 Prothioconazole 25% EC 25% EC 250 700 35.04 27.00 - -
T14 Prothioconazole 25% EC 25% EC 200 700 36.00 25.00 - -
T15 Prothioconazole 25% EC 25% EC 150 700 36.96 23.00 - -
T16 Cymoxanil 50% WP 50% WP 75 150 40.80 15.00 - -
T17 Cymoxanil 50% WP 50% WP 90 180 39.84 17.00 - -
T18 Cymoxanil 50% WP 50% WP 55 110 42.24 12.00 - -
T19 Pyraoxystrobin 20% SC 20% SC 65 500 36.48 24.00 - -
T20 Pyraoxystrobin 20% SC 20% SC 80 500 35.52 26.00 - -
T21 Pyraoxystrobin 20% SC 20% SC 55 500 36.96 23.00 - -
T22 Untreated Control - - - 48.00 - - -

Table 78: Effect on yield of Fungicidal Compositions of table 77
TN Treatments a.i. % Dose Yield
(t/ha) % Yield increase over control E CR
g. a.i. / ha gm - ml /ha

T1 Prothioconazole 25% + Cymoxanil 7.5% + Pyraoxystrobin 6.5% SC 25+7.5+6.5 250+75+65 1000 15.20 289.74 14.86 1.02
T2 Prothioconazole 20% + Cymoxanil 9% + Pyraoxystrobin 8% SC 20+9+8 200+90+80 1000 15.04 285.64 14.96 1.01
T3 Prothioconazole 15% + Cymoxanil 5.5% + Pyraoxystrobin 5.5% WP 15+5.5+5.5 150+55+55 1000 14.10 261.54 13.82 1.02
T4 Prothioconazole 25% EC + Cymoxanil 50% WP 25% EC + 50% WP 250+75 700 + 150 8.60 120.51 9.86 0.87
T5 Prothioconazole 25% EC + Cymoxanil 50% WP 25% EC + 50% WP 200+90 700 + 180 7.90 102.56 9.20 0.86
T6 Prothioconazole 25% EC + Cymoxanil 50% WP 25% EC + 50% WP 150+55 700 + 110 8.10 107.69 8.90 0.91
T7 Prothioconazole 25% EC + Pyraoxystrobin 20% SC 25% EC + 20% SC 250 +65 700 + 500 7.20 84.62 11.31 0.64
T8 Prothioconazole 25% EC + Pyraoxystrobin 20% SC 25% EC + 20% SC 200 +80 700 + 500 8.12 108.21 11.30 0.72
T9 Prothioconazole 25% EC + Pyraoxystrobin 20% SC 25% EC + 20% SC 150+55 700 + 500 7.30 87.18 10.32 0.71
T10 Cymoxanil 50% WP + Pyraoxystrobin 20% SC 50% WP + 20% SC 75+65 150 + 500 8.43 116.15 9.33 0.90
T11 Cymoxanil 50% WP + Pyraoxystrobin 20% SC 50% WP + 20% SC 90+80 180 + 500 7.30 87.18 10.20 0.72
T12 Cymoxanil 50% WP + Pyraoxystrobin 20% SC 50% WP + 20% SC 55+55 110 + 500 8.42 115.90 10.32 0.82
T13 Prothioconazole 25% EC 25% EC 250 700 6.10 56.41 - -
T14 Prothioconazole 25% EC 25% EC 200 700 5.30 35.90 - -
T15 Prothioconazole 25% EC 25% EC 150 700 5.20 33.33 - -
T16 Cymoxanil 50% WP 50% WP 75 150 4.00 2.56 - -
T17 Cymoxanil 50% WP 50% WP 90 180 4.12 5.64 - -
T18 Cymoxanil 50% WP 50% WP 55 110 3.90 0.00 - -
T19 Pyraoxystrobin 20% SC 20% SC 65 500 5.55 42.31 - -
T20 Pyraoxystrobin 20% SC 20% SC 80 500 6.34 62.56 - -
T21 Pyraoxystrobin 20% SC 20% SC 55 500 5.40 38.46 - -
T22 Untreated Control - - - 3.90 - - -

Table 79: Efficacy of Fungicidal Compositions of Prothioconazole + Cymoxanil + Pyraoxystrobin in Chilli Crop against Die back

TN Treatments a.i. % Dose Mean after two applications E CR
g. a.i. / ha gm - ml /ha Die back
PDI% %ROC
T1 Prothioconazole 20% + Cymoxanil 6% + Trifloxystrobin 1% SC 20+6+1 200+60+10 1000 9.18 82.00 51.82 1.58
T2 Prothioconazole 16% + Cymoxanil 8% + Trifloxystrobin 2% SC 16+8+2 160+80+20 1000 10.71 79.00 51.88 1.52
T3 Prothioconazole 12% + Cymoxanil 6% + Trifloxystrobin 3% WP 12+6+3 120+60+30 1000 12.24 76.00 49.89 1.52
T4 Prothioconazole 25% EC + Cymoxanil 50% WP 25% EC + 50% WP 200+60 700 + 120 33.15 35.00 35.76 0.98
T5 Prothioconazole 25% EC + Cymoxanil 50% WP 25% EC + 50% WP 160+80 700 + 160 33.66 34.00 34.64 0.98
T6 Prothioconazole 25% EC + Cymoxanil 50% WP 25% EC + 50% WP 120+60 700 + 120 35.19 31.00 31.36 0.99
T7 Prothioconazole 25% EC + Trifloxystrobin 42.6% SC 25% EC + 42.6% SC 200+10 700 + 253 28.56 44.00 45.25 0.97
T8 Prothioconazole 25% EC + Trifloxystrobin 42.6% SC 25% EC + 42.6% SC 160+20 700 + 253 29.07 43.00 43.76 0.98
T9 Prothioconazole 25% EC + Trifloxystrobin 42.6% SC 25% EC + 42.6% SC 120+30 700 + 253 30.09 41.00 43.06 0.95
T10 Cymoxanil 50% WP + Trifloxystrobin 42.6% SC 50% WP + 42.6% SC 60+10 120 + 253 34.68 32.00 34.00 0.94
T11 Cymoxanil 50% WP + Trifloxystrobin 42.6% SC 50% WP + 42.6% SC 80+20 160 + 253 33.66 34.00 36.36 0.94
T12 Cymoxanil 50% WP + Trifloxystrobin 42.6% SC 50% WP + 42.6% SC 60+30 120 + 253 34.17 33.00 35.76 0.92
T13 Prothioconazole 25% EC 25% EC 200 700 37.23 27.00 - -
T14 Prothioconazole 25% EC 25% EC 160 700 38.76 24.00 - -
T15 Prothioconazole 25% EC 25% EC 120 700 39.78 22.00 - -
T16 Cymoxanil 50% WP 50% WP 60 120 44.88 12.00 - -
T17 Cymoxanil 50% WP 50% WP 80 160 43.86 14.00 - -
T18 Trifloxystrobin 42.6% SC 42.6% SC 10 253 38.25 25.00 - -
T19 Trifloxystrobin 42.6% SC 42.6% SC 20 253 37.74 26.00 - -
T20 Trifloxystrobin 42.6% SC 42.6% SC 30 253 37.23 27.00 - -
T21 Untreated Control - - - 51.00 - - -

Table 80: Effect on yield of Fungicidal Compositions of table 79
TN Treatments a.i. % Dose Yield (t/ha) % Yield increase over control E CR
g.a.i. / ha gm - ml /ha

T1 Prothioconazole 20% + Cymoxanil 6% + Trifloxystrobin 1% SC 20+6+1 200+60+10 1000 17.00 233.33 16.65 1.02
T2 Prothioconazole 16% + Cymoxanil 8% + Trifloxystrobin 2% SC 16+8+2 160+80+20 1000 16.89 231.18 16.77 1.01
T3 Prothioconazole 12% + Cymoxanil 6% + Trifloxystrobin 3% WP 12+6+3 120+60+30 1000 16.12 216.08 15.97 1.01
T4 Prothioconazole 25% EC + Cymoxanil 50% WP 25% EC + 50% WP 200+60 700 + 120 9.00 76.47 11.19 0.80
T5 Prothioconazole 25% EC + Cymoxanil 50% WP 25% EC + 50% WP 160+80 700 + 160 8.40 64.71 11.08 0.76
T6 Prothioconazole 25% EC + Cymoxanil 50% WP 25% EC + 50% WP 120+60 700 + 120 7.40 45.10 11.45 0.65
T7 Prothioconazole 25% EC + Trifloxystrobin 42.6% SC 25% EC + 42.6% SC 200+10 700 + 253 7.45 46.08 12.15 0.61
T8 Prothioconazole 25% EC + Trifloxystrobin 42.6% SC 25% EC + 42.6% SC 160+20 700 + 253 8.23 61.37 12.20 0.67
T9 Prothioconazole 25% EC + Trifloxystrobin 42.6% SC 25% EC + 42.6% SC 120+30 700 + 253 8.00 56.86 10.79 0.74
T10 Cymoxanil 50% WP + Trifloxystrobin 42.6% SC 50% WP + 42.6% SC 60+10 120 + 253 8.20 60.78 10.95 0.75
T11 Cymoxanil 50% WP + Trifloxystrobin 42.6% SC 50% WP + 42.6% SC 80+20 160 + 253 7.80 52.94 11.27 0.69
T12 Cymoxanil 50% WP + Trifloxystrobin 42.6% SC 50% WP + 42.6% SC 60+30 120 + 253 8.24 61.57 10.79 0.76
T13 Prothioconazole 25% EC 25% EC 200 700 6.40 25.49 - -
T14 Prothioconazole 25% EC 25% EC 160 700 6.20 21.57 - -
T15 Prothioconazole 25% EC 25% EC 120 700 6.00 17.65 - -
T16 Cymoxanil 50% WP 50% WP 60 120 5.12 0.39 - -
T17 Cymoxanil 50% WP 50% WP 80 160 5.20 1.96 - -
T18 Trifloxystrobin 42.6% SC 42.6% SC 10 253 5.80 13.73 - -
T19 Trifloxystrobin 42.6% SC 42.6% SC 20 253 6.14 20.39 - -
T20 Trifloxystrobin 42.6% SC 42.6% SC 30 253 6.40 25.49 - -
T21 Untreated Control - - - 5.10 - - -

Table 81: Efficacy of Fungicidal Compositions of Prothioconazole + Dimethomorph + Fenaminstrobin in Chilli Crop against Die back

TN Treatments a.i. % Dose Mean after two applications E CR
g. a.i. / ha gm - ml /ha Die back
PDI% %ROC
T1 Prothioconazole 17.5% + Dimethomorph 30% + Fenaminstrobin 7.5% SC 17.5+30+7.5 175+300+75 1000 13.20 70.00 52.19 1.34
T2 Prothioconazole 15% + Dimethomorph 25% + Fenaminstrobin 9% SC 15+25+9 150+250+90 1000 14.08 68.00 49.60 1.37
T3 Prothioconazole 20% + Dimethomorph 20% + Fenaminstrobin 10% WP 20+20+10 200+200+100 1000 11.00 75.00 59.05 1.27
T4 Prothioconazole 25% EC + Dimethomorph 50% WP 25% EC + 50% WP 175+300 700 + 1000 28.60 35.00 36.25 0.97
T5 Prothioconazole 25% EC + Dimethomorph 50% WP 25% EC + 50% WP 150+250 700 + 1000 32.12 27.00 28.00 0.96
T6 Prothioconazole 25% EC + Dimethomorph 50% WP 25% EC + 50% WP 200+200 700 + 1000 29.92 32.00 37.00 0.86
T7 Prothioconazole 25% EC + Fenaminstrobin 20% SC 25% EC + 20% SC 175+75 700 + 500 26.40 40.00 43.75 0.91
T8 Prothioconazole 25% EC + Fenaminstrobin 20% SC 25% EC + 20% SC 150+90 700 + 500 26.40 40.00 44.00 0.91
T9 Prothioconazole 25% EC + Fenaminstrobin 20% SC 25% EC + 20% SC 200+100 700 + 500 24.20 45.00 54.50 0.83
T10 Dimethomorph 50% WP + Fenaminstrobin 20% SC 50% WP + 20% SC 300+75 1000 + 500 31.68 28.00 36.25 0.77
T11 Dimethomorph 50% WP + Fenaminstrobin 20% SC 50% WP + 20% SC 250+90 1000 + 500 30.80 30.00 37.00 0.81
T12 Dimethomorph 50% WP + Fenaminstrobin 20% SC 50% WP + 20% SC 200+100 1000 + 500 27.28 38.00 41.50 0.92
T13 Prothioconazole 25% EC 25% EC 175 700 33.00 25.00 - -
T14 Prothioconazole 25% EC 25% EC 150 700 35.20 20.00 - -
T15 Prothioconazole 25% EC 25% EC 200 700 30.80 30.00 - -
T16 Dimethomorph 50% WP 50% WP 300 1000 37.40 15.00 - -
T17 Dimethomorph 50% WP 50% WP 250 1000 39.60 10.00 - -
T18 Dimethomorph 50% WP 50% WP 200 1000 39.60 10.00 - -
T19 Fenaminstrobin 20% SC 20% SC 75 500 33.00 25.00 - -
T20 Fenaminstrobin 20% SC 20% SC 90 500 30.80 30.00 - -
T21 Fenaminstrobin 20% SC 20% SC 100 500 28.60 35.00 - -
T22 Untreated Control - - - 44.00 - - -

Table 82: Effect on yield of Fungicidal Compositions of table 81
TN Treatments a.i. % Dose Yield (t/ha) % Yield increase over control E CR
g.a.i. / ha gm - ml /ha

T1 Prothioconazole 17.5% + Dimethomorph 30% + Fenaminstrobin 7.5% SC 17.5+30+7.5 175+300+75 1000 12.80 341.38 11.74 1.09
T2 Prothioconazole 15% + Dimethomorph 25% + Fenaminstrobin 9% SC 15+25+9 150+250+90 1000 11.80 306.90 11.26 1.05
T3 Prothioconazole 20% + Dimethomorph 20% + Fenaminstrobin 10% WP 20+20+10 200+200+100 1000 14.10 386.21 12.73 1.11
T4 Prothioconazole 25% EC + Dimethomorph 50% WP 25% EC + 50% WP 175+300 700+ 1000 6.90 137.93 7.87 0.88
T5 Prothioconazole 25% EC + Dimethomorph 50% WP 25% EC + 50% WP 150+250 700+ 1000 6.60 127.59 7.07 0.93
T6 Prothioconazole 25% EC + Dimethomorph 50% WP 25% EC + 50% WP 200+200 700+ 1000 7.00 141.38 8.04 0.87
T7 Prothioconazole 25% EC + Fenaminstrobin 20% SC 25% EC + 20% SC 175+75 700+ 500 7.86 171.03 8.89 0.88
T8 Prothioconazole 25% EC + Fenaminstrobin 20% SC 25% EC + 20% SC 150+90 700+ 500 7.50 158.62 8.51 0.88
T9 Prothioconazole 25% EC + Fenaminstrobin 20% SC 25% EC + 20% SC 200+100 700+ 500 8.00 175.86 9.94 0.80
T10 Dimethomorph 50% WP + Fenaminstrobin 20% SC 50% WP + 20% SC 300+75 1000+ 500 6.80 134.48 7.19 0.95
T11 Dimethomorph 50% WP + Fenaminstrobin 20% SC 50% WP + 20% SC 250+90 1000 + 500 6.90 137.93 7.37 0.94
T12 Dimethomorph 50% WP + Fenaminstrobin 20% SC 50% WP + 20% SC 200+100 1000 + 500 7.25 150.00 9.94 0.73
T13 Prothioconazole 25% EC 25% EC 175 700 4.90 68.97 - -
T14 Prothioconazole 25% EC 25% EC 150 700 4.20 44.83 - -
T15 Prothioconazole 25% EC 25% EC 200 700 5.10 75.86 - -
T16 Dimethomorph 50% WP 50% WP 300 1000 3.12 7.59 - -
T17 Dimethomorph 50% WP 50% WP 250 1000 3.00 3.45 - -
T18 Dimethomorph 50% WP 50% WP 200 1000 3.10 6.90 - -
T19 Fenaminstrobin 20% SC 20% SC 75 500 4.20 44.83 - -
T20 Fenaminstrobin 20% SC 20% SC 90 500 4.50 55.17 - -
T21 Fenaminstrobin 20% SC 20% SC 100 500 5.10 75.86 - -
T22 Untreated Control - - - 2.90 - - -

Table 83: Efficacy of Fungicidal Compositions of Prothioconazole + Dimethomorph + Pyraoxystrobin in Chilli Crop against Die back

TN Treatments a.i. % Dose Mean after two applications E CR
g. a.i. / ha gm - ml /ha Die back
PDI% %ROC
T1 Prothioconazole 15% + Dimethomorph 30% + Pyraoxystrobin 5% SC 15+30+5 150+300+50 1000 8.36 78.00 53.46 1.46
T2 Prothioconazole 25% + Dimethomorph 25% + Pyraoxystrobin 6% SC 25+25+6 250+250+60 1000 7.60 80.00 53.76 1.49
T3 Prothioconazole 20% + Dimethomorph 20% + Pyraoxystrobin 8% WP 20+20+8 200+200+80 1000 9.50 75.00 53.34 1.41
T4 Prothioconazole 25% EC + Dimethomorph 50% WP 25% EC + 50% WP 150+300 700 + 1000 25.08 34.00 37.95 0.90
T5 Prothioconazole 25% EC + Dimethomorph 50% WP 25% EC + 50% WP 250+250 700 + 1000 24.70 35.00 37.52 0.93
T6 Prothioconazole 25% EC + Dimethomorph 50% WP 25% EC + 50% WP 200+200 700 + 1000 25.46 33.00 35.20 0.94
T7 Prothioconazole 25% EC + Pyraoxystrobin 20% SC 25% EC + 20% SC 150+50 700 + 500 22.42 41.00 45.25 0.91
T8 Prothioconazole 25% EC + Pyraoxystrobin 20% SC 25% EC + 20% SC 250+60 700 + 500 21.28 44.00 47.46 0.93
T9 Prothioconazole 25% EC + Pyraoxystrobin 20% SC 25% EC + 20% SC 200+80 700 + 500 22.04 42.00 48.16 0.87
T10 Dimethomorph 50% WP + Pyraoxystrobin 20% SC 50% WP + 20% SC 300+50 1000 + 500 25.46 33.00 36.25 0.91
T11 Dimethomorph 50% WP + Pyraoxystrobin 20% SC 50% WP + 20% SC 250+60 1000 + 500 25.84 32.00 34.88 0.92
T12 Dimethomorph 50% WP + Pyraoxystrobin 20% SC 50% WP + 20% SC 200+80 1000 + 500 26.22 31.00 35.20 0.88
T13 Prothioconazole 25% EC 25% EC 150 700 27.74 27.00 - -
T14 Prothioconazole 25% EC 25% EC 250 700 26.98 29.00 - -
T15 Prothioconazole 25% EC 25% EC 200 700 27.36 28.00 - -
T16 Dimethomorph 50% WP 50% WP 300 1000 32.30 15.00 - -
T17 Dimethomorph 50% WP 50% WP 250 1000 33.44 12.00 - -
T18 Dimethomorph 50% WP 50% WP 200 1000 34.20 10.00 - -
T19 Pyraoxystrobin 20% SC 20% SC 50 500 28.50 25.00 - -
T20 Pyraoxystrobin 20% SC 20% SC 60 500 28.12 26.00 - -
T21 Pyraoxystrobin 20% SC 20% SC 80 500 27.36 28.00 - -
T22 Untreated Control - - - 38.00 - - -

Table 84: Effect on yield of Fungicidal Compositions of table 83
TN Treatments a.i. % Dose Yield (t/ha) % Yield increase over control E CR
g. a.i. / ha gm - ml /ha

T1 Prothioconazole 15% + Dimethomorph 30% + Pyraoxystrobin 5% SC 15+30+5 150+300+50 1000 12.10 303.33 11.72 1.03
T2 Prothioconazole 25% + Dimethomorph 25% + Pyraoxystrobin 6% SC 25+25+6 250+250+60 1000 11.65 288.33 11.35 1.03
T3 Prothioconazole 20% + Dimethomorph 20% + Pyraoxystrobin 8% WP 20+20+8 200+200+80 1000 13.90 363.33 12.73 1.09
T4 Prothioconazole 25% EC + Dimethomorph 50% WP 25% EC + 50% WP 150+300 700 + 1000 5.50 83.33 7.85 0.70
T5 Prothioconazole 25% EC + Dimethomorph 50% WP 25% EC + 50% WP 250+250 700 + 1000 5.90 96.67 7.17 0.82
T6 Prothioconazole 25% EC + Dimethomorph 50% WP 25% EC + 50% WP 200+200 700 + 1000 6.30 110.00 8.04 0.78
T7 Prothioconazole 25%EC + Pyraoxystrobin 20% SC 25% EC + 20% SC 150+50 700 + 500 7.90 163.33 8.89 0.89
T8 Prothioconazole 25% EC + Pyraoxystrobin 20% SC 25% EC + 20% SC 250+60 700 + 500 8.00 166.67 8.51 0.94
T9 Prothioconazole 25% EC + Pyraoxystrobin 20% SC 25% EC + 20% SC 200+80 700 + 500 7.80 160.00 9.94 0.78
T10 Dimethomorph 50% WP + Pyraoxystrobin 20% SC 50% WP + 20% SC 300+50 1000 + 500 6.00 100.00 7.17 0.84
T11 Dimethomorph 50% WP + Pyraoxystrobin 20% SC 50% WP + 20% SC 250+60 1000 + 500 5.70 90.00 7.46 0.76
T12 Dimethomorph 50% WP + Pyraoxystrobin 20% SC 50% WP + 20% SC 200+80 1000 + 500 5.30 76.67 9.94 0.53
T13 Prothioconazole 25% EC 25% EC 150 700 4.90 63.33 - -
T14 Prothioconazole 25% EC 25% EC 250 700 4.20 40.00 - -
T15 Prothioconazole 25% EC 25% EC 200 700 5.10 70.00 - -
T16 Dimethomorph 50% WP 50% WP 300 1000 3.10 3.33 - -
T17 Dimethomorph 50% WP 50% WP 250 1000 3.10 3.33 - -
T18 Dimethomorph 50% WP 50% WP 200 1000 3.10 3.33 - -
T19 Pyraoxystrobin 20% SC 20% SC 50 500 4.20 40.00 - -
T20 Pyraoxystrobin 20% SC 20% SC 60 500 4.50 50.00 - -
T21 Pyraoxystrobin 20% SC 20% SC 80 500 5.10 70.00 - -
T22 Untreated Control - - - 3.00 - - -

It is evident from the above tables 57-84 that the fungicidal compositions of the present invention gave excellent control on crops against tested fungi-pests wherein all the prepared fungicidal compositions found synergistic as compared to the reference products (solo or binary compositions). It has also been found that use of the compositions of present invention not only gave better efficiency by using low a.i., content compared to binary and solo composition but also broaden the spectrum of compositions as the solo and binary compositions are not providing sufficient fungi-pests control in given duration.

Phytotoxicity Observations: Fungicidal compositions of the present invention were found completely safe (non-phytotoxic) on tested crops. In the above field trials, phytotoxicity was assessed for the synergistic composition of the present invention. For phytotoxicity evaluation on Potatoes and Chilli, following observations were made by observing temporary or long lasting damage to the leaves if any viz., leaf injury on tips and leaf surface, wilting, vein clearing, necrosis, epinasty and hyponasty after 10 days of spray of the synergistic fungicidal compositions of the present invention. Crop injury was observed on visual rating from 1-10 scale as given in Table 85. Table 86 provides phytotoxic effect of the synergistic compositions of the present invention on Potatoes and Chilli.

Table 85:

Rating Crop Injury (%) Verbal Description
0 - No symptoms
1 1-10 Very slight discoloration
2 11-20 More severe, but not lasting
3 21-30 Moderate and more lasting
4 31-40 Medium and lasting
5 41-50 Moderately heavy
6 51-60 Heavy
7 61-70 Very Heavy
8 71-80 Nearly destroyed
9 81-90 Destroyed
10 91-100 Completely destroyed

Table 86: Phytotoxic effect of synergistic compositions of the present invention on Potatoes and Chilli crop

Treatments
Dose (ml/ha) Phytotoxicity rating
Leaf tip injury Wilting Vein Clearing Necrosis Epinasty Hyponasty
Prothioconazole 20% + Cyazofamid 2.5% + Azoxystrobin 10% SC 1000 0 0 0 0 0 0
Prothioconazole 15% + Cyazofamid 4.5% + Azoxystrobin 8% SC 1000 0 0 0 0 0 0
Prothioconazole 10% + Cyazofamid 6% + Azoxystrobin 6% WP 1000 0 0 0 0 0 0
Prothioconazole 20% + Cyazofamid 4% + Fenaminstrobin 9% SC 1000 0 0 0 0 0 0
Prothioconazole 15% + Cyazofamid 6% + Fenaminstrobin 5% SC 1000 0 0 0 0 0 0
Prothioconazole 17.5% + Cyazofamid 2% + Fenaminstrobin 7% WP 1000 0 0 0 0 0 0
Prothioconazole 20% + Cyazofamid 2.5% + Picoxystrobin 12% SC 1000 0 0 0 0 0 0
Prothioconazole 15% + Cyazofamid 4.5% + Picoxystrobin 15% SC 1000 0 0 0 0 0 0
Prothioconazole 12% + Cyazofamid 6.5% + Picoxystrobin 10% WP 1000 0 0 0 0 0 0
Prothioconazole 20% + Cyazofamid 2% + Pyraclostrobin 6% SC 1000 0 0 0 0 0 0
Prothioconazole 16% + Cyazofamid 4% + Pyraclostrobin 8% SC 1000 0 0 0 0 0 0
Prothioconazole 12% + Cyazofamid 6% + Pyraclostrobin 6% WP 1000 0 0 0 0 0 0
Prothioconazole 25% + Cyazofamid 6.5% + Pyraoxystrobin 6.5% SC 1000 0 0 0 0 0 0
Prothioconazole 20% + Cyazofamid 6.5% + Pyraoxystrobin 8% SC 1000 0 0 0 0 0 0
Prothioconazole 15% + Cyazofamid 4.5% + Pyraoxystrobin 4.5% WP 1000 0 0 0 0 0 0
Prothioconazole 20% + Cyazofamid 3% + Trifloxystrobin 3% SC 1000 0 0 0 0 0 0
Prothioconazole 15% + Cyazofamid 5% + Trifloxystrobin 2% SC 1000 0 0 0 0 0 0
Prothioconazole 18% + Cyazofamid 7% + Trifloxystrobin 1% SC 1000 0 0 0 0 0 0
Prothioconazole 20% + Cymoxanil 6%+ Azoxystrobin 10% SC 1000 0 0 0 0 0 0
Prothioconazole 16% + Cymoxanil 8%+ Azoxystrobin 8% SC 1000 0 0 0 0 0 0
Prothioconazole 10% + Cymoxanil 5%+ Azoxystrobin 5% WP 1000 0 0 0 0 0 0
Prothioconazole 20% + Cymoxanil 8% + Fenaminstrobin 9% SC 1000 0 0 0 0 0 0
Prothioconazole 15% + Cymoxanil 6% + Fenaminstrobin 5% SC 1000 0 0 0 0 0 0
Prothioconazole 20% + Cymoxanil 5% + Fenaminstrobin 7% WP 1000 0 0 0 0 0 0
Prothioconazole 20% + Cymoxanil 6% + Picoxystrobin 15% SC 1000 0 0 0 0 0 0
Prothioconazole 15% + Cymoxanil 8% + Picoxystrobin 18% SC 1000 0 0 0 0 0 0
Prothioconazole 12% + Cymoxanil 10% + Picoxystrobin 10% WP 1000 0 0 0 0 0 0
Prothioconazole 20% + Cymoxanil 6% + Pyraclostrobin 6% SC 1000 0 0 0 0 0 0
Prothioconazole 16% + Cymoxanil 8% + Pyraclostrobin 8% SC 1000 0 0 0 0 0 0
Prothioconazole 12% + Cymoxanil 6% + Pyraclostrobin 6% WP 1000 0 0 0 0 0 0
Prothioconazole 25% + Cymoxanil 7.5% + Pyraoxystrobin 6.5% SC 1000 0 0 0 0 0 0
Prothioconazole 20% + Cymoxanil 9% + Pyraoxystrobin 8% SC 1000 0 0 0 0 0 0
Prothioconazole 15% + Cymoxanil 5.5% + Pyraoxystrobin 5.5% WP 1000 0 0 0 0 0 0
Prothioconazole 20% + Cymoxanil 6% + Trifloxystrobin 1% SC 1000 0 0 0 0 0 0
Prothioconazole 16% + Cymoxanil 8% + Trifloxystrobin 2% SC 1000 0 0 0 0 0 0
Prothioconazole 12% + Cymoxanil 6% + Trifloxystrobin 3% WP 1000 0 0 0 0 0 0
Prothioconazole 17.5% + Dimethomorph 30% + Fenaminstrobin 7.5% SC 1000 0 0 0 0 0 0
Prothioconazole 15% + Dimethomorph 25% + Fenaminstrobin 9% SC 1000 0 0 0 0 0 0
Prothioconazole 20% + Dimethomorph 20% + Fenaminstrobin 10% WP 1000 0 0 0 0 0 0
Prothioconazole 15% + Dimethomorph 30% + Pyraoxystrobin 5% SC 1000 0 0 0 0 0 0
Prothioconazole 25% + Dimethomorph 25% + Pyraoxystrobin 6% SC 1000 0 0 0 0 0 0
Prothioconazole 20% + Dimethomorph 20% + Pyraoxystrobin 8% WP 1000 0 0 0 0 0 0

It is evident from the above tables 86 that the use of fungicidal compositions of the present invention did not produce any phytotoxic symptoms on the crops.

From the foregoing it will be observed that numerous modifications and variations can be effectuated without departing from the true spirit and scope of the novel concepts of the present invention. It is to be understood that no limitations with respect to the specific embodiments illustrated is intended or should be inferred. It should be understood that all such modifications and improvements have been deleted herein for the sake of conciseness and readability but are properly within the scope of the following claims.
,CLAIMS:We Claim:
1. A synergistic fungicidal compositions comprising:
a) first fungicide A, Prothioconazole;
b) second fungicide B, selected from Cyazofamid, Cymoxanil or Dimethomorph;
c) third fungicide C, selected from Azoxystrobin, Fenaminstrobin, Picoxystrobin, Pyraclostrobin, Pyraoxystrobin or Trifloxystrobin; and
d) agriculturally acceptable excipients.

2. The synergistic fungicidal compositions as claimed in claim 1, wherein,
a) Prothioconazole is present in an amount in the range from 5 to 30 % w/w;
b) Cyazofamid is present in an amount in the range from 0.1 to 10 % w/w or Cymoxanil is present in an amount in the range from 2 to 13 % w/w or Dimethomorph is present in an amount in the range from 15 to 35 % w/w;
c) Azoxystrobin is present in an amount in the range from 2 to 15% w/w or Fenaminstrobin is present in an amount in the range from 2 to 15% w/w or Picoxystrobin is present in an amount in the range from 4 to 24% w/w or Pyraclostrobin is present in an amount in the range from 2 to 12% w/w or Pyraoxystrobin is present in an amount in the range from 1 to 12% w/w or Trifloxystrobin is present in an amount in the range from 0.1 to 5% w/w.

3. The synergistic fungicidal compositions as claimed in claim 1, wherein,
a) Prothioconazole is present in an amount in the range from 10 to 25 % w/w;
b) Cyazofamid is present in an amount in the range from 2 to 7% w/w or Cymoxanil is present in an amount the range from 5 to 10 % w/w or Dimethomorph is present in an amount in the range from 20 to 30 % w/w;
c) Azoxystrobin is present in an amount in the range from 5 to 10% w/w or Fenaminstrobin is present in an amount in the range from 5 to 10% w/w or Picoxystrobin is present in an amount in the range from 10 to 18% w/w or Pyraclostrobin is present in an amount in the range from 6 to 8% w/w or Pyraoxystrobin is present in an amount in the range from 4.5 to 8% w/w or Trifloxystrobin is present in an amount in the range from 1 to 3% w/w.

4. The synergistic fungicidal compositions as claimed in claim 1, wherein the composition is one of:
a) Prothioconazole is present in an amount in the range from 10 to 25% w/w and Cyazofamid is present in an amount in the range from 2 to 7% w/w and Azoxystrobin is present in an amount in the range from 5 to 10% w/w or Fenaminstrobin is present in an amount in the range from 5 to 10% w/w or Picoxystrobin is present in an amount in the range from 10 to 18% w/w or Pyraclostrobin is present in an amount in the range from 6 to 8% w/w or Pyraoxystrobin is present in an amount in the range from 4.5 to 8% w/w or Trifloxystrobin is present in an amount in the range from 1 to 3% w/w and agriculturally acceptable excipients;
b) Prothioconazole is present in an amount in the range from 10 to 25% w/w and Cymoxanil is present in an amount in the range from 5 to 10% w/w and Azoxystrobin is present in an amount in the range from 5 to 10% w/w or Fenaminstrobin is present in an amount in the range from 5 to 10% w/w or Picoxystrobin is present in an amount in the range from 10 to 18% w/w or Pyraclostrobin is present in an amount in the range from 6 to 8% w/w or Pyraoxystrobin is present in an amount in the range from 4.5 to 8% w/w or Trifloxystrobin is present in an amount in the range from 1 to 3% w/w and agriculturally acceptable excipients;
c) Prothioconazole is present in an amount in the range from 15 to 25% w/w and Dimethomorph is present in an amount in the range from 20 to 30% w/w and Fenaminstrobin is present in an amount in the range from 7.5 to 10% w/w or Pyraoxystrobin is present in an amount in the range from 5 to 8% w/w and agriculturally acceptable excipients;

5. The synergistic fungicidal compositions as claimed in claim 1, wherein the compositions is one of:
a) Prothioconazole is present in an amount in the range from 10 to 20% w/w and Cyazofamid is present in an amount in the range from 2.5 to 6.0% w/w and Azoxystrobin is present in an amount in the range from 6 to 10% w/w and agriculturally acceptable excipients;
b) Prothioconazole is present in an amount in the range from 15 to 20% w/w and Cyazofamid is present in an amount in the range from 2.0 to 6.0% w/w and Fenaminstrobin is present in an amount in the range from 5 to 9% w/w and agriculturally acceptable excipients;
c) Prothioconazole is present in an amount in the range from 12 to 20% w/w and Cyazofamid is present in an amount in the range from 2.5 to 6.5% w/w and Picoxystrobin is present in an amount in the range from 10 to 15% w/w and agriculturally acceptable excipients;
d) Prothioconazole is present in an amount in the range from 12 to 20% w/w and Cyazofamid is present in an amount in the range from 2 to 6% w/w and Pyraclostrobin is present in an amount in the range from 6 to 8% w/w and agriculturally acceptable excipients;
e) Prothioconazole is present in an amount in the range from 15 to 25% w/w and Cyazofamid is present in an amount in the range from 2.5 to 6.5% w/w and Pyraoxystrobin is present in an amount in the range from 4.5 to 8% w/w and agriculturally acceptable excipients;
f) Prothioconazole is present in an amount in the range from 15 to 25% w/w and Cyazofamid is present in an amount in the range from 3 to 7% w/w and Trifloxystrobin is present in an amount in the range from 1 to 3% w/w and agriculturally acceptable excipients;
g) Prothioconazole is present in an amount in the range from 10 to 20% w/w and Cymoxanil is present in an amount in the range from 5 to 8% w/w and Azoxystrobin is present in an amount in the range from 5 to 10% w/w and agriculturally acceptable excipients;
h) Prothioconazole is present in an amount in the range from 15 to 20% w/w and Cymoxanil is present in an amount in the range from 5 to 8% w/w and Fenaminstrobin is present in an amount in the range from 5 to 9% w/w and agriculturally acceptable excipients;
i) Prothioconazole is present in an amount in the range from 12 to 20% w/w and Cymoxanil is present in an amount in the range from 6 to 10% w/w and Picoxystrobin is present in an amount in the range from 10 to 18% w/w and agriculturally acceptable excipients;
j) Prothioconazole is present in an amount in the range from 12 to 20% w/w and Cymoxanil is present in an amount in the range from 6 to 8% w/w and Pyraclostrobin is present in an amount in the range from 6 to 8% w/w and agriculturally acceptable excipients;
k) Prothioconazole is present in an amount in the range from 15 to 25% w/w and Cymoxanil is present in an amount in the range from 5.5 to 9% w/w and Pyraoxystrobin is present in an amount in the range from 5.5 to 8% w/w and agriculturally acceptable excipients;
l) Prothioconazole is present in an amount in the range from 12 to 20% w/w and Cymoxanil is present in an amount in the range from 6 to 8% w/w and Trifloxystrobin is present in an amount in the range from 1 to 3% w/w and agriculturally acceptable excipients;
m) Prothioconazole is present in an amount in the range from 15 to 20% w/w and Dimethomorph is present in an amount in the range from 20 to 30% w/w and Fenaminstrobin is present in an amount in the range from 7.5 to 10% w/w and agriculturally acceptable excipients;
n) Prothioconazole is present in an amount in the range from 15 to 25% w/w and Dimethomorph is present in an amount in the range from 20 to 30% w/w and Pyraoxystrobin is present in an amount in the range from 5 to 8% w/w and agriculturally acceptable excipients;

6. The synergistic fungicidal compositions as claimed in claim 1, wherein the compositions are formulated as Suspension concentrate (SC), Dispersible concentrate (DC), Dustable powder (DP), Powder for dry seed treatment (DS), Flowable concentrate for seed treatment (FS), Oil-dispersion (OD), Water dispersible granules (WDG/WG), Wettable powder (WP), Water dispersible powder for slurry seed treatment (WS), Water dispersible tablet (WT), preferably Suspension concentrate (SC), and Wettable powder (WP).

7. The synergistic fungicidal compositions, as claimed in claim 1, wherein the agriculturally acceptable excipient is selected from the group comprising dispersing agent, wetting agent, dispersing cum wetting agent, anti-freezing agent, defoamer, biocide, thickener, pH stabilizer, anti-caking agent, diluent or filler.

8. The synergistic fungicidal compositions as claimed in claim 7, wherein,
a) the dispersing agent is selected from the group comprising polymethyl methacrylate-polyethylene glycol graft copolymer, acrylate copolymer liquid dispersant, condensed methyl naphthalene sulfonate sodium salt, acrylate copolymer grafted with PEG, polyoxy ethylene alkyl aryl phosphate amine salt, poly-carboxylate dispersant, sodium polycarboxylate, modified styrene acrylic polymeric dispersant, sodium lignosulphonate, sodium salt of naphthalene sulfonate condensate or a combination thereof, and present in an amount in the range from 0.1 to 20% w/w;
b) the wetting agent is selected from the group comprising polyoxyethylene alkyl ether, sodium alkyl naphthalene sulfonate blend, Adsee 2610 (non-ionic proprietary blend of supplier), polyalkylene oxide block copolymer, ethoxylated tristyrylphenol, sodium isopropyl naphthalene sulfonate, sodium butyl naphthalene sulfonate, sodium dioctylsulphosuccinate or a combination thereof, and present in an amount in the range from 0.1 to 10% w/w;
c) the dispersing cum wetting agent is selected from the group comprising proprietary blend of phosphate ester and sodium naphthalene sulphate formaldehyde condensate, Jeemox SCR (proprietary blend of supplier), modified styrene acrylic polymeric dispersant or a combination thereof, and present in an amount in the range from 2 to 10% w/w;
d) the anti-freezing agent is selected from the group comprising glycerol, propylene glycol, diethylene glycol, monoethylene glycol or a combinations thereof, and present in an amount in the range from 1 to 10% w/w;
e) the defoamer is selected from the group comprising polydimethylsiloxane antifoam emulsion, silicon emulsion, polysiloxane emulsion or a combination thereof, and present in an amount in the range from 0.01 to 2% w/w;
f) the biocide is selected from the group comprising 20% aqueous dipropylene glycol solution of 1, 2-benzisothiazolin-3-one, formaldehyde, isothiazolinone or a combinations thereof, and present in an amount in the range from 0.01 to 1% w/w;
g) the thickener is selected from the group comprising xanthan gum, welan gum, guar gum, polyvinyl alcohol, carboxymethylcellulose, polyvinylpyrrolidone, carboxyvinyl polymer, acrylic polymer, starch derivative, polysaccharide, high purity silica, white carbon or a combination thereof, and present in an amount in the range from 0.1 to 0.5% w/w;
h) the pH stabilizer is citric acid and present in an amount in the range from 0.1 to 1.0% w/w;
i) the anticaking agent is selected from the group comprising precipitated silica, organic bentonite, polyolefin particles, fumed silica or a combination thereof, and present in an amount in the range from 1 to 3% w/w;
j) the filler is selected from the group comprising, silica, precipitated silica, sodium bicarbonate, china clay, lactose, bentonite clay, kaolin, diatomaceous earth or a combination thereof, and present in an amount quantity sufficient; and
k) the diluents is demineralized water and present in an amount quantity sufficient.