DESC:FIELD OF THE INVENTION:
The present invention relates to novel synergistic herbicidal compositions and methods related thereto. More particularly, the present invention relates to a synergistic herbicidal composition comprising Chlorimuron ethyl, Mesotrione, Tembotrione and agriculturally acceptable formulation additives, and the method of preparation and use thereof as herbicides for the control of weeds in agricultural crops, in particular weeds in Sugarcane crop.
BACKGROUND OF THE INVENTION:
Weeds are undesirable plants that can severely damage yield in crops. Further, weeds are a persistent problem that needs constant monitoring. Several herbicides and methods of using such herbicides to control weed species are known in the art. Chemical herbicides are typically categorized according to the time of application (e.g., pre-emergence or post-emergence herbicides). Pre-emergence herbicides are applied prior to germination of weed for control of germinating seeds without harming the desired plant species. Post-emergence herbicides are applied after planting and over the top of establishing or established plants for control of weed species.
Moreover, current methods of attempting to control weeds include applications of pre-emergent herbicides followed by post emergent herbicides i.e. sequential applications of herbicides to address the issue of weeds in agricultural crop cultivation. Most of the rice lands under cultivation are weeded by hand, hence, significant human effort and time are expended in raising rice. Most of the times, the dosage used varies as the herbicide selection is not based on the technical knowhow which results in poor weed control affecting the productivity of the crop. Additionally, farmers are using different herbicidal combinations without knowing the mode of action and the weed spectrum. Due to lack of knowledge, there is inappropriate and/or under dosage of the weed products and this frequently leads to resistance development or poor control of the weeds. Similarly, other conventional methods of producing agricultural crops include the use of different combinations of herbicides such as tank mix herbicides to address the issue of emerged weeds without having proper application knowledge of the weed spectrum individual herbicides. In such usage the chances of varied dosage of individual herbicides end up with poor weed control, phytotoxicity on rice crop resulting in poor productivity. Therefore, successful weed management is essential for economical rice production. Furthermore, environmental considerations increasingly require that lower amounts of herbicidal active substances be used in the control of undesired vegetation.
It is known to overcome this type of problem to some extent by the use of herbicidal compositions in which more than one type of herbicide is present. Such compositions, however, should preferably still show the advantageous properties of the individual herbicide constituents and display a synergistic effect between them, whilst maintaining selectivity of herbicidal action with respect to the crop. It is, nonetheless, difficult to determine appropriate combinations of herbicides in view of the considerable number of different types of herbicides available and the plurality of individual herbicides within each such type.
Chlorimuron-ethyl, chemical name: ethyl 2- (4-chloro-6-methoxypyrimidin-2-ylcarbamoylsulfamoyl) benzoate. Blocking acetolactate synthase (ALS) activity in plants and interrupting valine and isoleucine synthesis. The chlorimuron-ethyl is a selective pre-emergence herbicide and post-emergence herbicide and is mainly used for preventing and removing broadleaf weeds in soybean fields. Chlorimuron-ethyl belongs to sulfonylurea herbicides, has an action mechanism of inhibiting the activity of acetolactate synthase in plants to interfere the synthesis of branched chain amino acid, and is mainly used for weeding soybeans and preventing and removing broadleaf weeds and certain gramineous weeds.
Mesotrione (2-[4-(methylsulfonyl)-2-nitrobenzoyl]-1,3-cyclohexanedione), is a herbicide developed for selective control of broad-leaved weeds along with some grass weeds in maize. Mesotrione is also now being used in cranberry crops for control of broad-leaved weeds. Mesotrione is effective for both preemergence and postemergence application, and unlike diuron, lower application rates are typically needed for satisfactory control from postemergence compared to preemergence applications. Although mesotrione is useful for postemergent weed control, it is weak on some weeds, particularly grasses. For control of these weeds, new solutions are desirable.
The tembotrione is one of triketone herbicides and belongs to HPPD inhibitor herbicides, the herbicidal activity of the tembotrione is shown by a 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitor, after the HPPD is inhibited, tyrosine is accumulated in the meristem of weeds and plastoquinone is deficient, after 3-5 days, the weeds have yellowing symptoms, and finally spread to the whole plant, and the weeds are albino and die. The tembotrione mainly prevents and removes annual setaria and wild Ribes weeds, and also can effectively prevent and remove a plurality of weeds such as thistle, convolvulus, veronica, capsicum, ambari, chamomile and cleavers.
WO 03/047340 and WO 2007/006415 describe herbicidal compositions comprising tembotrione. However, in practice, there are frequently disadvantages associated with the use of the herbicidal compositions known from these documents. Thus, the herbicidal activity is not always satisfactory or undesirable damage to the rice plants is observed with a satisfactory herbicidal activity.
However, still there is a need to develop a novel synergistic herbicidal composition which overcomes some of the existing problems and which will exhibit better effectiveness with optimum use of both actives at minimum herbicide application rate or concentration. A minimum application rate reduces not only the amount of an active substance required for the application but generally also reduces the amounts of formulation auxiliaries necessary. Both reduce the economic cost and improve the ecological compatibility of the herbicide treatment.
The inventors of the present invention also found that the novel synergistic herbicidal composition of Chlorimuron ethyl, Mesotrione and Tembotrione with agriculturally acceptable formulation additives exhibit qualities such as but not limited to stability, easy application, easy dose adjustment, no phytotoxicity, broad spectrum, better efficacy, minimal impact on environment, and better compliance, wherein said composition is designated for its use for controlling undesired vegetation in Sugarcane crop.
OBJECTIVE OF THE INVENTION:
The main objective of the present invention is to provide a novel synergistic herbicidal composition comprising Chlorimuron ethyl, Mesotrione, Tembotrione and one or more inactive excipient.
Another objective of the present invention is to provide a process for the preparation of a novel synergistic herbicidal composition comprising a combination of Chlorimuron ethyl, Mesotrione, Tembotrione and one or more inactive excipient.
Another objective of the present invention is to provide a novel synergistic herbicidal composition comprising a combination of Chlorimuron ethyl, Mesotrione, Tembotrione and one or more inactive excipient.
Yet another objective of the present invention is to provide a novel synergistic herbicidal composition which exhibit better effectiveness with optimum use of both actives at lower herbicide application rate or concentration for management and control of weeds in Sugarcanecrop.
Yet another objective of the present invention is to provide an herbicidal composition that efficaciously contributes in Herbicide Resistance Management (HRM).
Yet another objective of the present invention is to provide an economical and cost-effective composition for management and control of weeds.
Yet another objective of the present invention is to provide a cost-effective and convenient method for the preparation of said composition, which is effective against a wide variety of weeds in crops, especially for management of weed flora in sugarcanecrop.
Yet another objective of the present invention is to provide a stable synergistic herbicidal composition which meets the environmental and economic requirements imposed on modern-day herbicides which are continually increasing, with regard, for example, to the spectrum of action, toxicity, selectivity, application rate, formation of residues, low costs and favorable preparation ability.
The present invention, described hereinafter, achieves at least one, and preferably more than one, of the above mentioned objectives of the invention.
SUMMARY OF THE INVENTION:
Accordingly, the present invention provides a novel synergistic herbicidal composition comprising Chlorimuron ethyl, Mesotrione, Tembotrione and agriculturally acceptable formulation additives.
In one aspect, the present invention provides a novel synergistic composition comprising Chlorimuron ethyl, Mesotrione, Tembotrione and one or more inactive excipient.

In another aspect, the present invention provides a process for the preparation of a novel synergistic herbicidal composition comprising Chlorimuron ethyl, Mesotrione, Tembotrione and one or more inactive excipient.
In yet another aspect, the present invention provides a novel synergistic herbicidal composition which exhibit better effectiveness with optimum use of both actives at minimal herbicide application rate or concentration for management and control of weeds in sugarcane crop.
In yet another aspect, the present invention provides a composition comprising Chlorimuron ethyl, Mesotrione, Tembotrione and one or more inactive excipient to control a wide variety of weeds in crops.
In yet another aspect, the present invention provides a composition that achieves increased yield in the crops to which it is applied.
In yet another aspect, the present invention provides a composition of Chlorimuron ethyl, Mesotrione, Tembotrione and one or more inactive excipient that causes an enhanced herbicidal activity.
DETAILED DESCRIPTION OF THE INVENTION:
ABBREVIATIONS
AE: Aerosol SG: Water soluble granule
CS: Capsule suspension SP: Water soluble powder
DP: Dustable powder SU: Ultra-low volume (ULV) suspension
EC: Emulsifiable concentrate ME: Micro-emulsion
EG: Emulsifiable granule OD: Oil dispersion
EW: Oil-in water or water in oil emulsion UL: Ultra-low volume liquid
e.g.: Example WDG: Water dispersible granule
GR: Granule WP: Wettable powder
SC: Suspension concentrate WT: Water dispersible tablet
SE: Suspo-emulsion.

DEFINITIONS
The foregoing definitions provided herein for the terminologies used in the present disclosure are for illustrative purpose only and in no manner limit, the scope of the present invention disclosed in the present disclosure.
It will be understood that the terminology used herein is for the purpose of describing embodiments only, and is not intended to be limiting. As used in this specification, the singular forms "a", "an" and "the" include plural referents unless the context clearly dictates otherwise. Thus, for example, the reference to "a surfactant" includes one or more of such surfactants.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one ordinary skilled in the art to which the invention pertains. Although other methods and materials similar, or equivalent, to those described herein can be used in the practice of the present invention, the preferred materials and methods are described herein.
As used herein, the terms "comprises", "comprising", "includes", "including", or any other variation.
Thereof, are intended to cover a non-exclusive inclusion, subject to any limitation explicitly indicated.
For example, a composition or a method that comprises a list of elements is not necessarily limited to only those elements but may include other elements not expressly listed or inherent to such composition, or method.
As used herein, the term “composition” or "formulation" can be used interchangeably, unless stated otherwise, is meant to encompass, and are not limited to, compositions or formulations containing the combination of Chlorimuron ethyl, Mesotrione and Tembotrione.
As used herein, the term “additive(s)” or "auxiliary agent(s)" or “agrochemically acceptable carrier(s)” can be used interchangeably and refers to inert substances which are commonly used as diluent, to provide stability or to increase the activity profile of the composition or formulation with or without having agrochemical activity or direct effect on the undesired phytopathogenic fungi and/or microorganisms.
As used herein, the term "agrochemically acceptable salts" are typically acid addition salts of inorganic or organic acids, preferably of hydrochloric acid, hydrobromic acid, sulfuric acid, nitric acid, perchloric acid, phosphoric acid, formic acid, acetic acid, trifluoroacetic acid, oxalic acid, malonic acid, toluenesulfonic acid or benzoic acid.
As used herein, the term “additive(s)” or "auxiliary agent(s)" or “agriculturally acceptable carrier(s)”can be used interchangeably and refers to inert substances which are commonly used as diluent, to provide stability or to increase the activity profile of the composition or formulation with or without having agrochemical activity.
Unless otherwise specified, % refers to % weight; and % weight refers to % of the weight of the respective component with respect to the total weight of the composition.
As used herein, the term “lower” or “minimal” or “minimum” can be used interchangeably and refers to the optimum concentration of active or inactive ingredients of formulation to achieve the expected efficacy.
As used herein, the term "effective amount" means the amount of the active substances in thecompositions to achieve an observable effect on growth, including the effects of necrosis, death,retardation, prevention, and removal, destruction, or otherwise diminishing the occurrence and activity of the target organism. The effective amount can vary for the various compositions used in the present invention. An effective amount of the compositions will also vary according to the prevailing conditions such as desired pesticidal effect and duration, weather, target species, locus, mode of application, and the like.
As used herein, the term “herbicide” shall mean an active ingredient that kills, controls or otherwise adversely modifies the growth of plants. As used herein, a herbicidally effective or vegetation controlling amount is an amount of active ingredient that causes a "herbicidal effect," i.e., an adversely modifying effect and includes deviations from natural development, killing, regulation, desiccation, retardation. The terms "plants" and "vegetation" include, but are not limited to, germinant seeds, emerging seedlings, plants emerging from vegetative propagules, and established vegetation.
As used herein, the term “plant parts” are understood to mean all above-ground and below-ground parts and organs of plants, such as shoot, leaf, flower and root, examples including leaves, needles, stems, stalks, flowers, fruit-bodies, fruits and seeds, and also roots, tubers and rhizomes. The plant parts also include harvested plants and vegetative and generative propagation material, for example seedlings, tubers, rhizomes, cuttings and seeds.
In one embodiment, the present invention relates to a novel synergistic herbicidal composition comprising Chlorimuron ethyl, Mesotrione and Tembotrione and one or more inactive excipient.
In another embodiment, the present invention provides a synergistic composition of Chlorimuron ethyl, Mesotrione and Tembotrione, wherein the composition is used as herbicidal composition. The composition is selected from suspension concentrate (SC), wettable granules (WG), wettable powder (WP), a water dispersible granule (WDG), a water dispersible tablet (WT), an ultra-low volu (ULV) liquid (UL), an ultra-low volume (ULV) suspension (SU), a water soluble powder (SP), a suspo-emulsion (SE), granule (GR), an emulsifiable granule (EG), an oil-in-water or water in oil emulsion (EW), an emulsifiable concentrate (EC), a micro-emulsion (ME), an oil dispersion (OD), a capsule suspension (CS), a dustable powder (DP) or an aerosol (AE).
In a specific embodiment, the present invention provides a Oil Dispersion (OD) composition of Chlorimuron ethyl, Mesotrione and Tembotrione.
The composition comprising organic or inorganic carrier material, including agrochemically acceptable additive(s) are selected from the group comprising of Emulsifier, wetting agent(s), Dispersing agent(s), Rheology modifier and carrier(s), or a combination thereof. The composition may also contain if desired, one or more auxiliaries customary for crop protection compositions.
Examples of emulsifiers include but not limited to calcium dodecyl benzene sulfonate, tristyryl phenyl ethoxylate, Ethylhexyl Stearoyl Polyhydroxysterate, Calcium dodecyl benzenesulphonatetriglyceride, calcium alkyl benzen sulfonate, either alone or mixtures thereof. The emulsifiers is present in an amount of from 2% to15 % by weight based on a total weight of the composition.
Examples of rheology modifier include but not limited to polysaccharides, carboxymethyl cellulose, bentonite clay, aluminum magnesium silicate, either alone or mixtures thereof. The rheology modifier is present in an amount of from 5% to15 % by weight based on a total weight of the composition
Examples of dispersing/co-dispersing agents include but not limited to methyl methacrylate polymer, sodium lignosulfonates; sodium naphthalene sulphonate formaldehyde condensates; tristyryl phenol ethoxylate phosphate esters, polyarylphenyl ether phosphate, polyalkelene glycol ether, tristyrylphenol phosphate ester, tristyrylphenol ethoxylate amine salt of phosphate, tristyrylphenol phosphate amine salt, tristyrylphenol ethoxylated, tristyryl phenol ethylated, acrylic co-polymer, acrylate copolymer, acrylic copolymer, acrylic copolymer sodium salt, alkyl naphthalene sulfonate formaldehyde condensate, alkyl naphthalene sulfonate, naphthalene sulfonic acid, sodium alkyl naphthalene sulfonate blend, sodium polycarboxylate, sodium polyacrylate, ethoxylated oleyl cetyl alcohol, ethoxylated tristryl phenol sulphate, ethoxylated fatty alcohol, polymeric non-aqueous dispersing agent, polyoxyethyleneisotridecanol, tristyrylphenol ethoxylate phosphate ester, sodium salt condensate with formaldehyde, aliphatic alcohol ethoxylates; alky ethoxylates; Dodecyl Benzene Sulphonic Acid Sodium Salt, EO-PO block copolymers; and graft copolymers, either alone or mixtures thereof. The dispersing is present in an amount of from 3% to10 % by weight based on a total weight of the composition.
Examples of wetting/co-wetting agents include but not limited to block copolymer, alkoxylated alcohol, ethoxylated propoxylated alcohol, polyalkoxylated butyl ether, sodium alkyl sulphate, sodium lauryl sulphate, sodium alkyl benzene sulfonate, dioctyl sulfosuccinate, polyoxyethylene sorbitol hexaoleate, polyoxyethylenesorbitan monolaurate, polyoxyethylene polyoxypropylenesorbitan monolaurate, polyoxyethylene lauryl ether, tristyrylphenol ethoxylated, alkoxyletedalcohol, alkyl naphthalene sulfonate formaldehyde condensate, block copolymer, sodium dioctyl sulpho succinate, alkyl phenol ethoxylates and aliphatic alcohol ethoxylates, either alone or mixtures thereof. The wetting agent is present in an amount of from 3% to 10 % by weight based on a total weight of the composition.
Examples of carrier(s) for use in the composition include, but not limited to, natural ground minerals, such as kaolin or china clay, oil, alumina, talc, chalk, quartz, attapulgite, montmorillonite, and diatomaceous earth, or synthetic ground minerals, such as highly dispersed silicic acid, aluminium oxide, silicates, N-Methyl-2-pyrrolidone and calcium phosphates and calcium hydrogen phosphates, crushed and fractionated natural minerals, such as calcite, marble, pumice, precipitated silica, sepiolite, bentonite, river sand, zeolites, starch, sand, talc, quartz, dolomite, synthetic granules of inorganic and organic ground materials and mixtures thereof.
In an embodiment, the composition is formulated in a form selected from the group comprising water-soluble concentrates (SL), emulsifiable concentrates (EC), emulsions (EW), micro-emulsions (ME), Suspension concentrates (SC), oil-based suspension concentrates (OD), flowable suspensions (FS), water-dispersible granules (WG), water-soluble granules (SG), wettable powders (WP), water soluble powders (SP), granules (GR), encapsulated granules (CG), fine granules (FG), macrogranules (GG), dry flowables (DF), aqueous Suspo-emulsions (SE), capsule suspensions (CS) and microgranules (MG). In a preferred embodiment, the herbicidal composition is in the form of Oil Dispersible (OD), water-dispersible granule (WDG) and wettable powder (WP).
In a preferred embodiment, the herbicidal composition of the present invention is formulated as an Oil Dispersion (OD).
In another embodiment, the present invention further provides a composition to control a wide variety of undesirable weeds, wherein the Chlorimuron ethyl is present in an amount ranging from 0.5-15%w/w, Mesotrione is present in an amount ranging from 5-25%w/w Tembotrione is present in an amount ranging from 5-25%w/w of the herbicidal composition.
In a preferred embodiment, Chlorimuron ethylis present in an amount 2%w/w, Mesotrione is present in an amount of 10%w/w and Tembotrione is present in an amount of 14%w/w of the herbicidal composition.
The herbicidal combination of the present invention maybe used to target weeds among the crops such corn, rice, wheat, barley, rye, oat, sorghum, cotton, soybean, maize common bean, hemp, peanut, buckwheat, beet, rapeseed, sunflower, sugar cane, tobacco, etc.; vegetables: solanaceous vegetables such as eggplant, tomato, pimento, pepper, potato, etc., cucurbit vegetables such as cucumber, pumpkin, zucchini, water melon, melon, squash, etc., cruciferous vegetables such as radish, white turnip, horseradish, kohlrabi, Chinese cabbage, cabbage, leaf mustard, broccoli, cauliflower, etc., asteraceous vegetables such as burdock, crown daisy, artichoke, lettuce, etc, liliaceous vegetables such as green onion, onion, garlic, and asparagus, ammiaceous vegetables such as carrot, parsley, celery, parsnip, etc., chenopodiaceous vegetables such as spinach, Swiss chard, etc., lamiaceous vegetables such as Perilla frutescens, mint, basil, etc, strawberry, sweet potato, Dioscorea japonica, colocasia, etc., flowers, foliage plants, turf grasses, fruits: pome fruits such apple, pear, quince, etc., stone fleshy fruits such as peach, plum, nectarine, Prunus mume, cherry fruit, apricot, prune, etc., citrus fruits such as orange, lemon, rime, grapefruit, etc., nuts such as chestnuts, walnuts, hazelnuts, almond, pistachio, cashew nuts, macadamia nuts, etc. berries such as blueberry, cranberry, blackberry, raspberry, etc., vines, kaki fruit, olive, plum, banana, oil palm, coffee, date palm, coconuts, etc., trees other than fruit trees; tea, mulberry, flowering plant, trees such as ash, birch, dogwood, Eucalyptus, Ginkgo biloba, lilac, maple, Quercus, poplar, Judas tree, Liquidambar formosana, plane tree, zelkova, Japanese arborvitae, fir wood, hemlock, juniper, Pinus, Picea, and Taxus cuspidate, etc..
Thus, in another aspect, the present invention provides a method of controlling weeds at a locus, the method comprising applying a combination comprising Chlorimuron ethyl, Mesotrione and Tembotrione to the locus.
In an embodiment, the present invention provides a method of controlling weeds at a locus for the burn down of weeds, said method comprising application at the locus of the weed a synergistic combination of Chlorimuron ethyl, Mesotrione and Tembotrione.
The target weeds may be selected from Urticaceae weeds: Urticaurens Polygonaceae weeds: Polygonum convolvulus, Polygonum lapathifolium, Polygonum pensylvanicum, Polygonum persicaria, Polygonum longisetum, Polygonum aviculare, Polygonum arenastrum, Polygonum cuspidatum, Rumex japonicus, Rumexcrispus, Rumexobtusifolius, Rumexacetosa; Portulacaceae weeds: Portulaca oleracea; Caryophyllaceae weeds: Stellaria media, Cerastiumholosteoides, Cerastiumglomeratum, Spergula arvensis, Silene gallica Molluginaceae weeds: Mollugoverticillata; Chenopodiaceae weeds: Chenopodium album, Chenopodium ambrosioides, Kochia scoparia, Salsola kali, Atriplex spp.; Amaranthaceae weeds: Echinochloa colona, Echinochloa Crus-galli, Leptochloachinensis, Cyperusiria Cyperusdifformis, Fimbristylis Spp., Monochoria vaginalis, Eclipta alba, Ludwigia Spp., Sagittaria Spp. and Marsilea Spp.; Amaranthus retroflexus, Amaranthus viridis, Amaranthus lividus, Amaranthus spinosus, Amaranthus hybridus, Amaranthus palmeri, Amaranthus rudis, Amaranthus patulus, Amaranthus tuberculatos, Amaranthus blitoides, Amaranthus deflexus, Amaranthus quitensis, Alternanthera philoxeroides, Alternanthera sessilis, Alternanthera tenella; Papaveraceae weeds: Papaver rhoeas, Argemone Mexicana; Brassicaceae weeds: Raphanusraphanistrum, Raphanus sativus, Sinapis arvensis, Capsella bursa-pastoris, Brassica juncea, Brassica campestris, Descurainiapinnata, Rorippaislandica, Rorippasylvestris, Thlaspiarvense, Myagrumrugosum, Lepidium virginicum, Coronopusdidymus; Dinebra weeds: Dinebra Americana, Dinebra aquatic, Dinebraaristidoides, Dinebrabromoides, Dinebracalycina, Dinebracaudata, Dinebrachinensis, Dinebra chloride, Dinebrachondrosioides, Dinebracoerulescens, Dinebracristata, Dinebracurtipendula, Dinebradecipiens, Dinebra divaricate, Dinebradivaricatissima, Dinebra dura, Dinebraguineensis, Dinebra hirsute, Dinebrahirta, Dinebrajuncifolia, Dinebraligulata, Dinebra lima, Dinebramelicoides, Dinebranealleyi, Dinebraneesii, Dinebrapanicea, Dinebrapanicoides, Dinebrapubescens, Dinebrarepens, Dinebrascabra, Dinebrasecunda, Dinebrasimoniana, Dinebrasouthwoodii, Dinebrasquarrosa, Dinebrasrilankensis, Dinebratuaensis, Dinebra verticillate, Dinebraretroflexa. Dinebrahaareri, Dinebramarquisensis, Dinebraperrieri, Dinebrapolycarpha, Dinebrasomalensis Capparaceae weeds: Cleome affinis; Fabaceae weeds: Aeschynomeneindica, Aeschynomenerudis, Sesbaniaexaltata, Cassia obtusifolia, Cassia occidentalis, Desmodiumtortuosum, Desmodiumadscendens, Trifoliumrepens, Pueraria lobata, Vicia angustifolia, Indigoferahirsuta, Indigoferatruxillensis, Vigna sinensis; Oxalidaceae weeds: Oxalis corniculata, Oxalis strica, Oxalis oxyptera; Geraniaceae weeds: Geranium carolinense, Erodium cicutarium; Euphorbiaceae weeds: Euphorbia helioscopia, Euphorbia maculate, Euphorbia humistrata, Euphorbia esula, Euphorbia heterophylla, Euphorbia brasiliensis, Acalyphaaustralis, Croton glandulosus, Croton lobatus, Phyllanthus corcovadensis, Ricinus communis; Malvaceae weeds: Abutilon theophrasti, Sidarhombiforia, Sidacordifolia, Sida spinosa, Sidaglaziovii, Sidasantaremnensis, Hibiscus trionum, Anodacristata, Malvastrumcoromandelianum Sterculiaceae weeds: Waltheriaindica; Violaceae weeds: Viola arvensis, Viola tricolor; Cucurbitaceae weeds: Sicyos angulatus, Echinocystislobata, Momordica charantia; Lythraceae weeds: Lythrumsalicaria, Ammaniabaccifera; Apiaceae weeds: Hydrocotylesibthorpioides; Sapindaceae weeds: Cardiospermumhalicacabum; Primulaceae weeds: Anagallis arvensis; Asclepiadaceae weeds: Asclepiassyriaca, Ampelamusalbidus; Rubiaceae weeds: Galiumaparine, Galiumspurium var. echinospermon, Spermacocelatifolia, Richardia brasiliensis, Borreriaalata; Convolvulaceae weeds: Ipomoea nil, Ipomoea hederacea, Ipomoea purpurea, Ipomoea hederacea var. integriuscula, Ipomoea lacunosa, Ipomoea triloba, Ipomoea acuminata, Ipomoea hederifolia, Ipomoea coccinea, Ipomoea quamoclit, Ipomoea grandifolia, Ipomoea aristolochiafolia, Ipomoea cairica, Convolvulus arvensis, Calystegiahederacea, Calystegia japonica, Merremiahedeacea, Merremiaaegyptia, Merremiacissoides, Jacquemontiatamnifolia; Boraginaceae weeds: Myosotis arvensis; Lamiaceae weeds: Lamium purpureum, Lamiumamplexicaule, Leonotisnepetaefolia, Hyptissuaveolens, Hyptislophanta, Leonurussibiricus, Stachys arvensis; Solanaceae weeds: Datura stramonium, Solanum nigrum, Solanum Americanum, Solanum ptycanthum, Solanum sarrachoides, Solanum rostratum, Solanum aculeatissimum, Solanum sisymbriifolium, Solanum carolinense, Physalis angulata, Physalis subglabrata, Nicandraphysaloides; Scrophulariaceae weeds: Veronica hederaefolia, Veronica persica, Veronica arvensis; Plantaginaceae weeds: Plantagoasiatica; Asteraceae weeds: Xanthium pensylvanicum, Xanthium occidentale, Helianthus annuus, Matricaria chamomilla, Matricariaperforata, Chrysanthemum segetum, Matricariamatricarioides, Artemisia princeps, Artemisia vulgaris, Artemisia verlotorum, solidagoaltissima, Taraxacumofficinale, Galinsogaciliata, Galinsogaparviflora, Senecio vulgaris, Seneciobrasiliensis, Seneciogrisebachii, Conyzabonariensis, Conyza canadensis, Ambrosia artemisiaefolia, Ambrosia trifida, Bidenspilosa, Bidensfrondosa, Bidenssubalternans, Cirsium arvense, Cirsium vulgare, Silybummarianum, Carduus nutans, Lactucaserriola, Sonchusoleraceus, Sonchus asper, Wedelia glauca, Melampodiumperfoliatum, Emilia sonchifolia, Tagetesminuta, Blainvillealatifolia, Tridaxprocumbens, Porophyllumruderale, Acanthospermumaustrale, Acanthospermumhispidum, Cardiospermumhalicacabum, Ageratum conyzoides, Eupatorium perfoliatum, Eclipta alba, Erechtiteshieracifolia, Gamochaeta spicata, Gnaphalium spicatum, Jaegeriahirta, Parthenium hysterophorus, Siegesbeckiaorientalis, Solivasessilis; Liliaceae weeds: Allium canadense, Allium vineale; Commelinaceae weeds: Commelinacommunis, Commelinabengharensis, Commelinaerecta; Poaceae weeds: Echinochloa crus-galli, Setariaviridis, Setariafaberi, Setaria glauca, Setariageniculata, Digitariaciliaris, Digitariasanguinalis, Digitariahorizontalis, Digitariainsularis, Eleusineindica, Poaannus, Alospecurusaequalis, Alopecurus myosuroides, Avenafatua, Sorghum halepense, Sorghum vulgare, Agropyronrepens, Loliummultiflorum, Loliumperenne, Loliumrigidum, Bromussecalinus, Bromus tectorum, Hordeumjubatum, Aegilops cylindrica, Phalarisarundinacea, Phalaris minor, Aperaspica-venti, Panicum dichotomiflorum, Panicum texanum, Panicum maximum, Brachiariaplatyphylla, Brachiariaruziziensis, Brachiariaplantaginea, Brachiariadecumbens, Brachiariabrizantha, Brachiariahumidicola, Cenchrusechinatus, Cenchruspauciflorus, Eriochloavillosa, Pennisetumsetosum, Chloris gayana, Eragrostispilosa, Rhynchelitrumrepens, Dactylocteniumaegyptium, Ischaemumrugosum, Oryza sativa, Paspalum notatum, Paspalummaritimum, Pennisetumclandestinum, Pennisetumsetosum, Rottboelliacochinchinensis; Cyperaceae weeds: Cyperusmicroiria, Cyperusiria, Cyperusodoratus, Cyperusrotundus, Cyperusesculentus, Kyllingagracillima, Equisetaceae weeds: Equisetum arvense, Equisetum palustre, Trianthema weeds, Onagraceae weeds: Ludwigiaparvifloraand the like.
Preferred control of Narrow Leaf / Grass Weeds:
1. Digitariaspp
2. Eleusineindica
3. Echinochloaspp
4. Cynodondactylon
5. Panicum repens
6. Imperatacylindrica
7. Paspalumspp
8. Avenafatua
9. Phalaris minor
10. Brachiariaspp
11. Setariaspp
12. Rottboelliaspp
13. Dinebraretroflexa
14. Dactylocteniumaegyptium

Preferred control of Broad Leaf Weeds:
1. Amaranthus spp.
2. Euphorbia spp.
3. Phyllannthus spp.
4. Parthenium hysterophorus
5. Ammanniabaccifera
6. Mollugo spp.
7. Ageratum conyzoides
8. Mimosa pudica
9. Stachytarphetaindica
10. Trianthema spp.
11. Commelina spp.
12. Digera arvensis
13. Borreriahispida
14. Celosia argentea
15. Acanthospermumhispidum
16. Rumex spp.
17. Medicago spp.
18. Coronopusdidymus
19. Chenopodium album
20. Lathyrusaphaca
21. Convolvulus arvensis
22. Ipomea spp.
23. Alternanthera spp.
24. Cleome spp.
25. Coccinia spp.
26. Tribulus terrestris
27. Cassia spp.
28. Physalis spp.
29. Eclipta spp.

Preferred control of Sedge Weeds:
1. Cyperusrotundus
2. Cyperusdifformis
3. Cyperusiria
4. Cyperusesculentus
5. Cyperusimbricatus
6. Other Cyperspp
7. Fimbristylisspp

In yet another preferred embodiment, the present invention provides aherbicidal combination or
composition comprising of Chlorimuron ethyl, Mesotrione and Tembotrione to control the weeds on economically important crops such as Sugarcane and Maize.
In an embodiment, combination of the present invention may be applied either early-post and post-emergent. In a preferred embodiment, the combination of the present invention may be used early-post and post-emergent or 1-10 leaf stage of weed. The advantage of the combination is surprisingly good residual effects, Broad spectrum and quick burndown of the weeds when applied early-post and post-emergent.
Examples:
The examples below are given solely for the purpose of illustration and are not to be construed as limitations of the present invention, as many variations thereof are possible without departing from the spirit and scope of the invention.
Example 1: Preparation of Herbicidal composition as Oil Dispersible (OD).

In an embodiment, the chemical composition of the present Herbicidalis depicted below in Table 1 (a) below:
Table-1: Composition of the Herbicidal composition
S.no. Ingredients Percentage range
1 Chlorimuron ethyl Technical 2.0% m/m
2 Mesotrione Technical 10.0% m/m
3 Tembotrione Technical 14.0% m/m
4 Ethylhexyl Stearoyl Polyhydroxysterate 05.0% m/m
5 Calcium dodecyl benzenesulphonate 10.0% m/m
6 Alcohols Ethoxylated 5.00% m/m
7 Dodecyl Benzene Sulphonic Acid Sodium Salt 5.00% m/m
8 Bentonite clay (Rheology modifier) 10.0% m/m
9 Oil carrier Q.S.

Preparation method of Oil dispersible.
a) Take the oil carrier into a high-shear mixing kettle.
b) Add Ethylhexyl Stearoyl Polyhydroxysterate and mix for 30 minutes.
c) Add Calcium Dodecylbenzenesulphonate, Alcohols Ethoxylated, and Dodecyl Benzene Sulphonic Acid Sodium Salt to the mixture.
d) Stir at 1500 RPM for an additional 30 minutes.
e) Add Chlorimuron Ethyl, Mesotrione, and Tembotrionetechnicals to the mixture one at a time.
f) Mix for 1 hour after adding each component.
g) Once mixing is complete, transfer the material to a Dyno mill.
h) Grind for 30 minutes to achieve the desired consistency.
i) Add an appropriate amount of the rheology modifier to finalize the formulation.
Table-1(a): Quality parameters of (Oil dispersible) OD formulation
S.no. Parameters Desired Quality
1 Description/ physical appearance
The material shall be form of the paleyellow colour cream liquid
2 A.I. content of
Chlorimuron ethyl 2.0% w/w (±15%)
Mesotrione10.0% w/w (±10%)
Tembotrione14.0% w/w (±6%)
3 Dispersion Stability Less than or equal to 2 ml creaming or sedimentation after 24.5h.
4 Persistence of foam
persistent of foam shall not be more than 60 ml in 12 min.
5 pH of 1% aq. Solution 3.0- 6.0
6 Pourability 05% max.
7 Wet Sieve Min. 98% through 75µm sieve
8 Heat stability test Take 100ml sample & keep it in 54°C±2 for 14 days.
9 Cold test Take 100ml sample & keep it in 5°C±2 for 14 days

Table-1(c): Composition of the Fungicidal composition
S.no. Ingredients Percentage range
1 Chlorimuron ethyl Technical 2.0% m/m

2 Mesotrione Technical 10.0% m/m
3 Tembotrione Technical 10.0% m/m
4 Sodium salt of naphthalene sulfonate condensate 05.0% m/m

5 Sodium alkyl naphthalene sulfonate 03.0% m/m

6 ß-D-galactopyranosyl-(1?4)-D-glucose 5.00% m/m
7 Ammonium sulphate 5.00% m/m

8 China clay Q.S

Preparation method of Wettable Powder .
Step 1. Place China clay into the premixing blender.
Step 2. Add surfactants to the blender and mix for 30 minutes to ensure thorough blending.
Step 3. Add the pre-mixed mass from Step 1 to Ammonium sulphate in the blender.
Step 4. Mix this combination for an additional 30 minutes.
Step 5. Add Chlorimuron ethyl and Tembotrione one by one to the blender, followed by Mesotrione.
Step 6. Mix all ingredients for 1 hour to ensure even distribution.
Step 7. After mixing, transfer the material to an ACM or Jet mill.
Step 8. Mill the material until the particle size reaches the desired fineness (=15µm).
Step 9. Transfer the milled material to the post-blender for final blending.

Example-2: Field evaluation of the bio-efficacy of the present Herbicidal composition.
Experimental design Randomized Block Design
Replication 3
Treatments 9
Crop Sugarcane
Plot size(m2) 48Sq.m.
Spacing 75cm (Row to Row)
Variety CO-0238
Type of formulation Oil Dispersion (OD)
Date of planting 02- Oil Dispersion (OD)05-2023

Application method Uniform application with knapsack sprayer fitted with flat fan nozzle
Time of application 25-30 days after planting of sugarcane at 2-4 leaf stages of weeds
Water volume 500 L/ha

Application Method: Measured quantity of the chemical was added to required volume of water @ 500L/ha for spraying. The spray tank was filled with ½ the quantity of clean required volume of water and then the measured chemical (according to the dose) was added followed by the rest half quantity of water. The solution was stirred well and thorough coverage was ensured.

Study details:
Bio efficacy and weed dry matter:
Herbicides were applied as post emergence at 2 to 4 leaf stage with the help of Knapsack sprayer fitted with flat fan nozzle with a water volume of 500 L/ha. A quadrate with a dimension of 1 m x 1 m was placed randomly at five places in each plot and the weeds from that area were counted and expressed as number per square meter. The total numbers of different weed species were counted at 15, 30, 45 and 60 days after applications. After sun drying, weed samples transferred to hot air oven for drying at 60 °C. Biomass of the weeds of each sample was recorded in g/m2 at 15, 30, 45 and 60 days after application.
Weed control efficiency:
The weed control efficiency (WCE) was calculated by adopting the formula given by Mani et al. (1976).
Weed dry weight of weedy check - Weed dry weight of treatment
WCE (%) = ----------------------------------------------------------------------------------- X 100

Weed dry weight of weedy check

Treatment details:
Table-2:“Chlorimuron ethyl 2.0% + Mesotrione 10.0% + Tembotrione 14.0% OD”.
Protocol-A: Treatment details: Code: JU (3) MW-021014: Sugarcane

Sr. No.
Treatment details Individual component dosages
(g a.i./ha) Combined dosages of all components
(g a.i./ha) Formulation dose/ha
(ml/gm)
T-1 Chlorimuron ethyl 2.0% + Mesotrione 10.0% + Tembotrione 14.0% OD 12.50 + 62.50 + 87.50 162.50 625
T-2 Chlorimuron ethyl 2.0% + Mesotrione 10.0% + Tembotrione 14.0% OD 18.75 + 93.75 + 131.25 243.75 937.5
T-3 Chlorimuron ethyl 2.0% + Mesotrione 10.0% + Tembotrione 14.0% OD 25.0 + 125.0 + 175.0 325.00 1250
T-4 Chlorimuron ethyl 2.0% + Mesotrione 10.0% + Tembotrione 14.0% OD 31.25 + 156.25 + 218.75 406.25 1562.5
T-5 Chlorimuron ethyl 2.0% + Mesotrione 10.0% + Tembotrione 14.0% OD 50.0 + 250.0 + 350.0 650.00 2500
T-6 Chlorimuron ethyl 25% WG (Market standard) 9.0 - 36.0
T-7 Mesotrione 10.0% SC (Market standard) 75.0 - 750.0
T-8 Tembotrione 42.0% SC (Market standard) 120.0 - 286.0
T-9 Untreated Check - - -

Table-3:Bio-efficacy of test herbicides against Sugarcane Weed Complex, 2023-24
Protocol-A: Code: JU (3) MW-021014
Sr. No. Treatment details Dosage (ga.i./ha) Percent Weed Control Efficacy (% WCE) at 15 Days After Application (DAA)
Narrow Leaves / Grasses Broad Leaves Sedges
T-1 Chlorimuron ethyl 2.0% + Mesotrione 10.0% + Tembotrione 14.0% OD 162.50 63.0 66.0 52.0
T-2 Chlorimuron ethyl 2.0% + Mesotrione 10.0% + Tembotrione 14.0% OD 243.75 68.0 71.0 57.0
T-3 Chlorimuron ethyl 2.0% + Mesotrione 10.0% + Tembotrione 14.0% OD 325.00 73.0 76.0 62.0
T-4 Chlorimuron ethyl 2.0% + Mesotrione 10.0% + Tembotrione 14.0% OD 406.25 76.0 79.0 65.0
T-5 Chlorimuron ethyl 2.0% + Mesotrione 10.0% + Tembotrione 14.0% OD 650.00 79.0 82.0 68.0
T-6 Chlorimuron ethyl 25% WG (Market standard) 9.00 9.0 36.0 32.0
T-7 Mesotrione 10.0% SC (Market standard) 75.00 28.0 26.0 9.0
T-8 Tembotrione 42.0% SC (Market standard) 120.00 33.0 36.0 23.0
T-9 Untreated Check - - - -
DAA-Days after application

Table-4: Bio-efficacy of test herbicides against Sugarcane Weed Complex, 2023-24
Protocol-A: Code: JU (3) MW-021014
Sr. No. Treatment details Dosage (g a.i./ha) Percent Weed Control Efficacy (% WCE) at 30 Days After Application (DAA)
Narrow Leaves / Grasses Broad Leaves Sedges
T-1 Chlorimuron ethyl 2.0% + Mesotrione 10.0% + Tembotrione 14.0% OD 162.50 65.0 68.0 54.0
T-2 Chlorimuron ethyl 2.0% + Mesotrione 10.0% + Tembotrione 14.0% OD 243.75 70.0 73.0 59.0
T-3 Chlorimuron ethyl 2.0% + Mesotrione 10.0% + Tembotrione 14.0% OD 325.00 78.0 81.0 67.0
T-4 Chlorimuron ethyl 2.0% + Mesotrione 10.0% + Tembotrione 14.0% OD 406.25 80.0 83.0 69.0
T-5 Chlorimuron ethyl 2.0% + Mesotrione 10.0% + Tembotrione 14.0% OD 650.00 82.0 85.0 71.0
T-6 Chlorimuron ethyl 25% WG (Market standard) 9.00 12.0 39.0 35.0
T-7 Mesotrione 10.0% SC (Market standard) 75.00 31.0 29.0 12.0
T-8 Tembotrione 42.0% SC (Market standard) 120.00 36.0 39.0 26.0
T-9 Untreated Check - - - -
DAA- Days after application

Table-5: Bio-efficacy of test herbicides against Sugarcane Weed Complex, 2023-24
Protocol-A: Code: JU (3) MW-021014
Sr. No. Treatment details
Dosage (g a.i./ha) Percent Weed Control Efficacy (% WCE) at 45 Days After Application (DAA)
Narrow Leaves / Grasses Broad Leaves Sedges
T-1 Chlorimuron ethyl 2.0% + Mesotrione 10.0% + Tembotrione 14.0% OD 162.50 67.0 70.0 56.0
T-2 Chlorimuron ethyl 2.0% + Mesotrione 10.0% + Tembotrione 14.0% OD 243.75 72.0 75.0 61.0
T-3 Chlorimuron ethyl 2.0% + Mesotrione 10.0% + Tembotrione 14.0% OD 325.00 83.0 86.0 72.0
T-4 Chlorimuron ethyl 2.0% + Mesotrione 10.0% + Tembotrione 14.0% OD 406.25 84.0 87.0 73.0
T-5 Chlorimuron ethyl 2.0% + Mesotrione 10.0% + Tembotrione 14.0% OD 650.00 86.0 89.0 75.0
T-6 Chlorimuron ethyl 25% WG (Market standard) 9.00 15.0 42.0 38.0
T-7 Mesotrione 10.0% SC (Market standard) 75.00 34.0 32.0 15.0
T-8 Tembotrione 42.0% SC (Market standard) 120.00 39.0 42.0 29.0
T-9 Untreated Check - - - -
DAA- Days after application

Table-6: Bio-efficacy of test herbicides against Sugarcane Weed Complex, 2023-24
Protocol-A: Code: JU (3) MW-021014
Sr. No. Treatment details Dosage (g a.i./ha) Percent Weed Control Efficacy (% WCE) at 60 Days After Application (DAA)
Narrow Leaves / Grasses Broad Leaves Sedges
T-1 Chlorimuron ethyl 2.0% + Mesotrione 10.0% + Tembotrione 14.0% OD 162.50 69.0 72.0 58.0
T-2 Chlorimuron ethyl 2.0% + Mesotrione 10.0% + Tembotrione 14.0% OD 243.75 74.0 77.0 63.0
T-3 Chlorimuron ethyl 2.0% + Mesotrione 10.0% + Tembotrione 14.0% OD 325.00 88.0 91.0 77.0
T-4 Chlorimuron ethyl 2.0% + Mesotrione 10.0% + Tembotrione 14.0% OD 406.25 89.0 92.0 78.0
T-5 Chlorimuron ethyl 2.0% + Mesotrione 10.0% + Tembotrione 14.0% OD 650.00 91.0 94.0 80.0
T-6 Chlorimuron ethyl 25% WG (Market standard) 9.00 18.0 45.0 41.0
T-7 Mesotrione 10.0% SC (Market standard) 75.00 37.0 35.0 18.0
T-8 Tembotrione 42.0% SC (Market standard) 120.00 42.0 45.0 32.0
T-9 Untreated Check - - - -
DAA- Days after application

Phytotoxicity:
Phytotoxicity was assessed for the testing herbicides in sugarcane crop. The observations on leaf tip injury, yellowing, necrosis, wilting, vein clearing, hyponasty and epinasty of sugarcane were recorded at 0, 1, 3, 5, 7 and 10 days after application of the chemical herbicides. The phytotoxicity symptoms were estimated by visual assessment on Phytotoxicity Rating Scale (PRS) i.e. 0-10 scale.
Phytotoxicity Rating Scale (PRS):
Grade Per cent leaf tip/surface injury Grade Per cent leaf tip/surface injury
0 0-0.00 6 51-60
1 0-10 7 61-70
2 11-20 8 71-80
3 21-30 9 81-90
4 31-40 10 91-100
5 41-50

Table7. Phytotoxicity of test in secticides for Leaf tip injury, Chlorosis, Scorching, Epinasty & Hyponasty in Sugarcane, 2023-24
Protocol-A: Code: JU (3) MW-021014
Sr. No. Treatments Dosage (ga.i./ha) Leaf tip injury/Chlorosis/Scorching/Epinasty or Hyponasty/Necrosis(%)
1DBA 1DAA 3DAA 7DAA 10DAA 14DAA
T-1 Chlorimuron ethyl 2.0% + Mesotrione 10.0% + Tembotrione 14.0% OD 162.50 0 0 0 0 0 0
T-2 Chlorimuron ethyl 2.0% + Mesotrione 10.0% + Tembotrione 14.0% OD 243.75 0 0 0 0 0 0
T-3 Chlorimuron ethyl 2.0% + Mesotrione 10.0% + Tembotrione 14.0% OD 325.00 0 0 0 0 0 0
T-4 Chlorimuron ethyl 2.0% + Mesotrione 10.0% + Tembotrione 14.0% OD 406.25 0 0 0 0 0 0
T-5 Chlorimuron ethyl 2.0% + Mesotrione 10.0% + Tembotrione 14.0% OD 650.00 0 0 0 0 0 0
T-6 Chlorimuron ethyl 25% WG (Market standard) 9.00 0 0 0 0 0 0
T-7 Mesotrione 10.0% SC (Market standard) 75.00 0 0 0 0 0 0
T-8 Tembotrione 42.0% SC (Market standard) 120.00 0 0 0 0 0 0
T-9 Untreated Check - 0 0 0 0 0 0
DBA-Days before application; DAA-Days after application

Marketable Yield:
The harvesting was done at physiological maturity, the cane yield of sugarcane was recorded treatment wise and the data thus collected were subjected for ANOVA (Gomez and Gomez, 1984; Hosmand, 1988). Further, in each treatment the additional gain in yield over untreated control is calculated as below:
Yield in treatment – yield in control
Additional gain yield (%) = x 100
Yield in control

Table-8: Bio-efficacy of test herbicides on marketable yield of Sugarcane, 2023-24
Protocol-A: Code: JU (3) MW-021014

Sr. No.
Treatments Dosage (ga.i./ha) Caneyield (q/ha) Percent
Increase over UT Check
T-1 Chlorimuron ethyl 2.0% + Mesotrione 10.0% + Tembotrione 14.0% OD 162.50 847.5 21.51
T-2 Chlorimuron ethyl 2.0% + Mesotrione 10.0% + Tembotrione 14.0% OD 243.75 872.5 25.09
T-3 Chlorimuron ethyl 2.0% + Mesotrione 10.0% + Tembotrione 14.0% OD 325.00 1007.5 44.44
T-4 Chlorimuron ethyl 2.0% + Mesotrione 10.0% + Tembotrione 14.0% OD 406.25 1017.5 45.88
T-5 Chlorimuron ethyl 2.0% + Mesotrione 10.0% + Tembotrione 14.0% OD 650.00 1022.5 46.59
T-6 Chlorimuron ethyl 25% WG (Market standard) 9.00 812.5 16.49
T-7 Mesotrione 10.0% SC (Market standard) 75.00 817.5 17.20
T-8 Tembotrione 42.0% SC (Market standard) 120.00 842.5 20.79
T-9 Untreated Check - 697.5 -
Q-Quintal; UT-Untreated; ha-hectare

Summary and Conclusion:
Evaluation of Bio-efficacy of Novel Herbicide Combinations Against Weed Complex in Sugarcane Crop
Overview: The evaluation of the novel trimix-herbicide combination “Chlorimuron ethyl 2.0% + Mesotrione 10.0% + Tembotrione 14.0% OD” (coded as JU (3) MW-021014) reveals promising results in controlling weed complexes in sugarcane crops. When applied at 25-30 days after planting (at the 2-4 leaf stage of weeds), this formulation outperformed market-standard products, providing superior and longer-lasting weed control without causing any phytotoxicity to the sugarcane plants.
1. Novel Trimix-Herbicide Combination (JU (3) MW-021014) - Protocol-A:
• Composition: Chlorimuron ethyl 2.0% + Mesotrione 10.0% + Tembotrione 14.0% OD
• Application: Applied at 25-30 days after planting of sugarcane crop when weeds are at the 2-4 leaf stage.
• Effectiveness: This combination demonstrated maximum control of the weed complex, with a longer duration of action compared to other tested formulations.
• Phytotoxicity: No phytotoxic effects observed on the sugarcane crop, highlighting its crop safety.
• Dosage: Treatment-3 (Protocol-A) was applied at 1250 ml/ha, equating to 25.0 + 125.0 + 175.0 g a.i./ha, which proved to be the most effective dosage for weed control.
2. Market-Standard Products Comparison:
• Effectiveness: The novel trimix combination (T-3) outperformed market-standard products applied alone (T-6 to T-8). It provided superior weed control with no adverse effects on the crop.
• Comparison with Other Treatments: Treatments T-1, T-2, T-4, and T-5 also showed effective control, but none reached the performance level of Treatment-3.
3. Best Treatment Option - Protocol-A (T-3):
• Composition: Chlorimuron ethyl 2.0% + Mesotrione 10.0% + Tembotrione 14.0% OD applied at 1250 ml/ha.
• Effectiveness: Treatment-3 was observed as the most suitable, effective, and economical option for controlling the weed complex in sugarcane.
• Synergistic Success: The formulation’s success lies in the positive synergy between the three active ingredients. Their unique ratio and composition contribute to enhanced weed control without harming the sugarcane crop.
4. Phytotoxicity:
• Protocol-A (T-3): The formulation did not cause any phytotoxicity at the tested dosages.
• Other Treatments (T-1 to T-5): No significant phytotoxicity was observed, but Treatment-3 still outperformed these in terms of efficacy and crop safety.
5. Impact on Weed Complex Control:
• Weed Control Duration: Treatment-3, along with Treatments T-4, T-5, T-2, and T-1, showed excellent control of the weed complex, but Treatment-3 provided the longest duration of effectiveness.
• Success of the Combination: The efficacy of the trimix combination is attributed to the synergistic effect of the three active molecules, providing optimal control of weeds without harming the crop.
Conclusion:
The Novel Trimix-Herbicide Combination of Chlorimuron ethyl 2.0% + Mesotrione 10.0% + Tembotrione 14.0% OD at 1250 ml/ha is the recommended formulation for managing the weed complex in sugarcane crops. It offers superior weed control, longer duration of action, and crop safety compared to market-standard herbicides. This combination is also economically beneficial for farmers, making it an optimal choice for effective weed management.
Impact on Yield:
Table 8 (Protocol-A), revealed that recently invented Novel Trimix Herbicide Combinations/Formulation of “Chlorimuron ethyl 2.0% + Mesotrione 10.0% + Tembotrione 14.0% OD” [(JU (3) MW-021014)], contributed significantly higher cane yield i.e. 1007.50 to 1022.50 q/ha, with an incremental of 44.44 to 46.59% (Protocol-A) over rest of the treatments or tested combinations and also found very close to each other (T-3 to T-5).
Phytotoxicity:
The data on phytotoxicity symptoms revealed that recently invented Novel Trimix Herbicide Combinations of JU (3) MW-021014 (Chlorimuron ethyl 2.0% + Mesotrione 10.0% + Tembotrione 14.0% OD) did not cause any phytotoxicity at any tested dosages on Sugarcane crop (Table 7, Protocol-A).
Conclusion:
Hence, “Chlorimuron ethyl 2.0% + Mesotrione 10.0% + Tembotrione 14.0% OD” and “Chlorimuron ethyl 2.0% + Tembotrione 10.0% + Mesotrione 14.0% OD” @ 1250ml/ha (25.0 + 125.0 + 175.0= 325.0 g a.i./ha) may be recommended in Sugarcane crop for the management of Weed complex, as well as it is found economically suitable to the farmer in terms of weed controlefficacy and efficiency based on the bioefficacy data of the experiments of respective combinations.
,CLAIMS: 1. A herbicidal composition comprising:
a) Chlorimuron ethyl;
b) Mesotrion; and
c) Tembotrione.
2. The herbicidal composition as claimed in claim 1, wherein Chlorimuron ethyl is in range of 0.5-15 wt.%, Mesotrion in range of 5-25 wt.%, Tembotrione in the range of 5-25 wt.% of the total composition.
3. The herbicidal composition as claimed in claim 1, comprising at least one agriculturally acceptable excipient
4. The herbicidal composition as claimed in claim 1, wherein said herbicidal composition is formulated in a form selected from the group consisting of water-soluble concentrates (SL), emulsifiable concentrates (EC), emulsions (EW), micro-emulsions (ME), Suspension concentrates (SC), oil-based suspension concentrates (OD), flowable suspensions (FS), water-dispersible granules (WDG), 15 water-soluble granules (SG), wettable powders (WP), water soluble powders (SP), dry flowables (DF), granules (GR), encapsulated granules (CG), fine granules (FG), macrogranules (GG), aqueous Suspo-emulsions (SE), capsule suspensions (CS), and microgranules (MG).
5. The herbicidal composition as claimed in claim 4, wherein said herbicidal composition is formulated in the form of a Oil dispersible (OD).
6. The herbicidal composition as claimed in claim 5, comprising at least a wetting agent; at least a dispersing agent; at least Rheology Modifier and at least Emulsifier; at least carrier.
7. The herbicidal composition as claimed in claim 6, wherein said wetting agents are selected form alkyl phenol ethoxylate, fatty oil ethoxylate, phenyl naphthalene sulphonates, alkyl naphthalene sulfonates, sodium alkyl naphthalene sulfonate, sodium salt of sulfonated alkyl carboxylate, dioctyl sulfosuccinate sodium salt polyoxyalkylated ethyl phenols, polyoxyethoxylated fatty alcohols, polyoxyethoxylated fatty amines, lignin derivatives, alkane sulfonates, alpha olefin sulfonates, alkylbenzene sulfonates, salts of polycarboxylic acids, salts of esters of sulfosuccinic acid, octyl phenol ether sulphate, anionic phosphate esters, disodium laureth sulfosuccinate, diisodecyl sodium sulfosuccinate, 5 alkylnaphthalenesulfonates, alkylbenzenesulfonates, alkylpolyglycol ether sulfonates, alkyl ether phosphates, alkyl ether sulfates and alkyl sulfosuccinic monoesters, and mixtures thereof.
8. The herbicidal composition as claimed in claim 6, wherein said dispersing agent is selected from lignosulphonates, phenyl naphthalene sulphonates, condensed methyl naphthalene sulfonate, polyaromatic sulfonates, sodium alkyl aryl sulfonates, maleic anhydride copolymers, phosphate esters, condensation products of aryl/alkyl sulphonic acids and formaldehyde, addition products of ethylene oxide and fatty acid esters, polycarboxylates alkali earth metal salt of alkylbenzene sulfonate, calcium dodecylbenzene sulfonate, salts of sulfonated naphthalene, polystyrenatedacrylated co- polymer, salts of polyacrylic acids, salts of phenol sulfonic acids, and mixtures thereof.
9. The herbicidal composition as claimed in claim 6, wherein said rheology modifier is selected polysaccharides, carboxymethyl cellulose, bentonite clay, aluminum magnesium silicate, either alone or mixtures thereof.
10. The herbicidal composition as claimed in claim 6, wherein said Emulsifier is selected calcium dodecyl benzene sulfonate, tristyryl phenyl ethoxylate, Ethylhexyl Stearoyl Polyhydroxysterate, Calcium dodecyl benzenesulphonatetriglyceride, calcium alkyl benzen sulfonate, either alone or mixtures thereof.
11. The herbicidal composition as claimed in claim 6, wherein said Carrier is selected from natural ground minerals, such as kaolin or china clay, oil, alumina, talc, chalk, quartz, attapulgite, montmorillonite, and diatomaceous earth, or synthetic ground minerals, such as highly dispersed silicic acid, aluminium oxide, silicates, N-Methyl-2-pyrrolidone and calcium phosphates and calcium hydrogen phosphates, crushed and fractionated natural minerals, such as calcite, marble, pumice, precipitated silica, sepiolite, bentonite, river sand, zeolites, starch, sand, talc, quartz, dolomite, synthetic granules of inorganic and organic ground materials and mixtures thereof.
12. A process for preparing aherbicidal composition as claimed in claim 1 as Oil dispersible formulation, said process comprising:
a) Take the oil carrier into a high-shear mixing kettle.
b) Add Ethylhexyl Stearoyl Polyhydroxysterate and mix for 30 minutes.
c) Add Calcium Dodecylbenzenesulphonate, Alcohols Ethoxylated, and Dodecyl Benzene Sulphonic Acid Sodium Salt to the mixture.
d) Stir at 1500 RPM for an additional 30 minutes.
e) Add Chlorimuron Ethyl, Mesotrione, and Tembotrionetechnicals to the mixture one at a time.
f) Mix for 1 hour after adding each component.
g) Once mixing is complete, transfer the material to a Dyno mill.
h) Grind for 30 minutes to achieve the desired consistency.
i) Add an appropriate amount of the rheology modifier to finalize the formulation.