Half Life Extending Moieties And Methods Of Using The Same

Abstract: The disclosure relates generally to biology and medicine, and more particularly it relates to compounds acting as half-life (t½)-extending moieties for use with therapeutics, especially for improving t½ of biological-based therapeutics (i.e., biotherapeutics or biologics). The disclosure further relates to fusions and conjugates that include one or more of the compounds acting as t½-extending moieties, as well as pharmaceutical compositions including the same and their use in treating various conditions, diseases or disorders.

Patent Information

Application #

Filing Date

14 July 2023

Publication Number

48/2023

Publication Type

INA

Invention Field

BIOTECHNOLOGY

Status

Email

Parent Application

Applicants

ELI LILLY AND COMPANY

LILLY CORPORATE CENTER Indianapolis, Indiana 46285

Inventors

1. FERRANTE, Andrea

c/o ELI LILLY AND COMPANY P.O. Box 6288 Indianapolis, Indiana 46206-6288

2. HEUER, Josef George

c/o ELI LILLY AND COMPANY P.O. Box 6288 Indianapolis, Indiana 46206-6288

3. LEE, Stacey Lynn

c/o ELI LILLY AND COMPANY P.O. Box 6288 Indianapolis, Indiana 46206-6288

4. VERDINO, Petra

c/o ELI LILLY AND COMPANY P.O. Box 6288 Indianapolis, Indiana 46206-6288

Specification

Documents

Application Documents

#	Name	Date
1	202317047517-STATEMENT OF UNDERTAKING (FORM 3) [14-07-2023(online)].pdf	2023-07-14
2	202317047517-Sequence Listing in txt [14-07-2023(online)].txt	2023-07-14
3	202317047517-Sequence Listing in PDF [14-07-2023(online)].pdf	2023-07-14
4	202317047517-POWER OF AUTHORITY [14-07-2023(online)].pdf	2023-07-14
5	202317047517-NOTIFICATION OF INT. APPLN. NO. & FILING DATE (PCT-RO-105-PCT Pamphlet) [14-07-2023(online)].pdf	2023-07-14
6	202317047517-FORM 1 [14-07-2023(online)].pdf	2023-07-14
7	202317047517-DECLARATION OF INVENTORSHIP (FORM 5) [14-07-2023(online)].pdf	2023-07-14
8	202317047517-COMPLETE SPECIFICATION [14-07-2023(online)].pdf	2023-07-14
9	202317047517-CLAIMS UNDER RULE 1 (PROVISIO) OF RULE 20 [14-07-2023(online)].pdf	2023-07-14
10	202317047517-FORM-26 [17-07-2023(online)].pdf	2023-07-17
11	202317047517-Proof of Right [18-08-2023(online)].pdf	2023-08-18
12	202317047517-Information under section 8(2) [07-12-2023(online)].pdf	2023-12-07
13	202317047517-FORM 3 [07-12-2023(online)].pdf	2023-12-07
14	202317047517-FORM 18 [21-01-2025(online)].pdf	2025-01-21