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Use Of Mevidalen And Other D1 Positive Allosteric Modulators For Slowing Of Parkinson's Disease Progression

Abstract: The present invention relates to methods of treating and dosing regimens using Mevidalen, also described as 2-(2,6-dichlorophenyl)-1-[(1S,3R)-3-(hydroxymethyl)-5-(3- hydroxy-3-methylbutyl)-1-methyl-3,4-dihydroisoquinolin-2(1H)-yl]ethanone, and/or pharmaceutical compositions thereof, for slowing Parkinson's disease progression.

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Patent Information

Application #
Filing Date
05 October 2023
Publication Number
36/2024
Publication Type
INA
Invention Field
CHEMICAL
Status
Email
Parent Application

Applicants

ELI LILLY AND COMPANY
Lilly Corporate Center Indianapolis, IN 46285

Inventors

1. BIGLAN, Kevin Michael
c/o Eli Lilly and Company P.O. Box 6288 Indianapolis, IN 46206-6288
2. SVENSSON, Kjell Anders Ivan
c/o Eli Lilly and Company P.O. Box 6288 Indianapolis, IN 46206-6288

Specification

Documents

Application Documents

# Name Date
1 202317066697-STATEMENT OF UNDERTAKING (FORM 3) [05-10-2023(online)].pdf 2023-10-05
2 202317066697-REQUEST FOR EXAMINATION (FORM-18) [05-10-2023(online)].pdf 2023-10-05
3 202317066697-POWER OF AUTHORITY [05-10-2023(online)].pdf 2023-10-05
4 202317066697-FORM 18 [05-10-2023(online)].pdf 2023-10-05
5 202317066697-FORM 1 [05-10-2023(online)].pdf 2023-10-05
6 202317066697-FIGURE OF ABSTRACT [05-10-2023(online)].pdf 2023-10-05
7 202317066697-DRAWINGS [05-10-2023(online)].pdf 2023-10-05
8 202317066697-DECLARATION OF INVENTORSHIP (FORM 5) [05-10-2023(online)].pdf 2023-10-05
9 202317066697-COMPLETE SPECIFICATION [05-10-2023(online)].pdf 2023-10-05
10 202317066697-Proof of Right [17-10-2023(online)].pdf 2023-10-17
11 202317066697-FORM 3 [05-04-2024(online)].pdf 2024-04-05