“Method Of Making Releasable Polymeric Reagents”

Abstract: The instant disclosure provides (among other things) improved methods of preparing fluorenyl- based polymeric reagents, methods of recovering and purifying such polymeric reagents, methods of reducing unwanted impurities in a fluorenyl-based polymeric reagent, fluorenyl- based polymeric reagents prepared by the methods described herein, and conjugates prepared by reaction with fluorenyl-based polymeric reagents prepared by the methods described herein.

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