DESC:FIELD OF THE INVENTION:

The present invention relates to a fungicidal composition comprising of a) Fungicide compound A is Fluxapyroxad or its agrochemically acceptable salts esters and derivatives; b) Fungicide compound B, Strobilurin is selected from Azoxystrobin, Picoxystrobin, Pyraclostrobin, Trifloxystrobin, Metominostrobin, Kresoxim methyl; c) Insecticide compound C is selected from Tolfenpyrad, Fluxametamide, Isocycloseram, Broflanilide, Chlorantraniliprole, Cyantraniliprole, Cyclaniliprole, Tetraniliprole, Pioxaniliprole, Methoxyfenozide, Chromafenozide, Tebufenozide, Emamectin benzoate, Indoxacarb, Novaluron; and d) one or more inactive excipients. The present invention further relates to process of preparing said composition along with one or more excipients and formulation thereof.

BACKGROUND OF THE INVENTION:

Combination of fungicides and insecticide are used to broaden the spectrum of control of insect–pests and fungi, to improve the pest control with synergistic effect, to mitigate the effect of biotic and abiotic stress on crop plants, to reduce dosage, thereby reducing environmental impact, decrease chances of resistance development and to enhance residual control so lesser the number of sprays for crop protections and minimizing the pesticidal load in ecosystem. The combination of fungicides and insecticides at times demonstrate an additive or synergistic effect that results in an improved control on the insect-pests and fungi.

Fungicides and insecticides in combination are used widely and very frequently in commercial agriculture and have enabled an enormous increase in crop yields and product quality which ultimately increased the ease to farmers in term of economic advantage as well as ease of farming activities.

There are many combinations of Fluxapyroxad along with other insecticide known in the prior art for the control of insect-fungi. For example, US9167818B2 relates to active compound combinations, in particular within a fungicide composition, which comprises fungicide compound A, prothioconazole and fungicide compound B Fluxapyroxad and optionally insecticide compound C, a further fungicidally active compound. Moreover, the invention relates to a method for curatively or preventively controlling the phytopathogenic fungicidally of plants or crops (e.g. cereals such as wheat, barley, lye, oats, millet and triticale; soya beans; rice; corn/maize; oil seed rape including canola; beans, peas, peanuts; sugar beet, fodder beet, beetroot; potatoes; cotton), and to the use of a combination according to the invention for the treatment of seed, to a method for protecting a seed and not at least to the treated seed.

US20190045784A1 relates to a Fungicidal mixtures comprising, as active components, 1) Fluxapyroxad and 2) one fungicidal compound I and/or 3) One insecticidal compound II, methods for controlling harmful fungi using mixtures of Fluxapyroxad and one fungicidal compound I and/or one insecticidal compound II, the use of Fluxapyroxad with one fungicidal compound I and/or one insecticidal compound II for preparing such mixtures, and also compositions and plant propagation material comprising such mixtures.

CN104585181A relates to an invention discloses a fungicidal composition containing Fluxapyroxad and prothioconazole. The fungicidal composition comprises the effective components Fluxapyroxad and prothioconazole in binary combination at the weight ratio of (1-50) to (50-1); the ratio of the effective components Fluxapyroxad and prothioconazole in the preparation in parts by weight is 1%-80%; and the balance is allowed and acceptable auxiliary components in the pesticide. The dosage forms of the fungicidal composition are missible oil, a suspending agent, wettable powder, water aqua, a water dispersible granule, an emulsion in water, a microemulsion, a granule and a microcapsule; and the fungicidal composition is mainly used for preventing and treating diseases such as sheath blight, gray mold, powdery mildew, blight, leaf spot disease and rust disease.

EP3536150A1 relates to an invention relates to fungicidal mixtures comprising, as active components, (I) and a copper containing substance (II) selected from Bordeaux mixture, copper acetate, copper hydroxide, copper oxychloride and basic copper sulfate, and optionally a third fungicidal compound III, wherein compound III is selected from groups (A) to (E), as well as methods to combat phytopathogenic fungi based on such mixtures.

CA2782433C relates to an invention relates to an agrochemical mixture for increasing the health of a plant comprising as active ingredients 1) an imidazolinone herbicide as compound (I) selected from the group consisting of imazamox, imazethapyr, imazapic, imazapyr, imazamethabenz-methyl and imazaquin; and 2) a fungicidal compound (II) selected from N-(3',4',5'-trifluorobiphenyl-2-yl)-3-difluoromethyl-1-methyl-1H-pyrazole-4-carboxamide (common name: Fluxapyroxad ) and boscalid in synergistically effective amounts. The present invention further relates to a method for improving the health of a plant, wherein the plant, the locus where the plant is growing or is expected to grow or plant propagation material from which the plant grows is treated with an effective amount of a mixture as defined above. In addition, the invention relates to the use of a mixture as defined above for synergistically increasing the health of a plant.

WO2020148660 relates to a synergistic combination of tolfenpyrad and pyraclostrobin with its composition and a method for controlling a wide variety of undesired pathogenic microorganisms, insect pests and mites, for a plant, including the treatment of plant/plant parts and a region around the plant. The present invention also discloses an enhanced efficacy against pests and diseases in comparison to individual components of the said combination. The combination also widens the spectrum and said to have longer residual effects against undesired pathogenic microorganisms, insect pests and mites.

There is however a need for improvement of these combinations. Single active combinations used over a long period of time has resulted in resistance. With the onset of resistance to certain fungi, there is a need in the art for a combination of actives that decreases chances of resistance and improves the spectrum of control over fungi, insect and pest.

However still there is a need for a composition comprises Fluxapyroxad; a strobilurin fungicide and an insecticide selected from a list. The present invention further relates to process of preparing said composition along with at least one inactive formulation excipients and formulation thereof which overcomes some of the existing problems and can be prepared easily without much complex manufacturing process.

In general use, the fungicides actives are used in the form of a dilute aqueous composition because it can attain a good interaction with the target organism. However, most active fungicide compounds that are used as fungicides are only sparingly or even insoluble in water. The low solubility of such compounds present the challenges and difficulties to formulator in formulating fungicide compounds in stable formulations that can be easily stored for a long time and which still have a high stability and effective activity until end use. This problem especially occurs and may get worsen if more than one active compound is present in the composition.

Therefore, one object of the present invention is to provide improved compositions of fungicides and insecticides for the control of fungi and insect-pests another object of the present invention is to provide a method and a composition for controlling fungi, insect and pests.

Yet another object of the present invention is to provide improved compositions of fungicides and insecticides that promote plant health and to increase plant or crop yield.
Another object of the present invention is to provide a fungicidal formulation that gives broad spectrum control of fungi and insect-pests in one shot application.

Further object of the present invention is to provide a fungicidal formulation that gives residual control i.e. longer duration of control.

Another object of the present invention is to provide a fungicidal formulation which prevents or causes delayed development of resistance to fungi against fungicides with a specific site/ mode of action.

Further object of the present invention is to provide a fungicidal formulation that gives synergistic control; i.e. grams of active ingredients required are less to achieve desired level of control.

Another object of the present invention is to provide a fungicidal formulation that gives immediate protection to crops.

Further object of the present invention is to provide a fungicidal formulation that has improved rain-fastness properties.

Another object of the present invention is to provide a fungicidal formulation with environment-friendly formulations; i.e. formulations are with minimum organic solvent as carrier.

Yet another object of the present invention is to provide a fungicidal formulation that is safe to the crops.

Still another object of the present invention is to provide a process for preparing a stable and non-phytotoxic formulation.

Embodiment of the present invention can ameliorate one or more of the above mentioned problems.

The present invention have found that the novel fungicidal composition of Fluxapyroxad; a Strobilurin fungicide and an insecticides. The present invention further relates to process of preparing said composition along with at least one inactive formulation excipients and formulation thereof as described herein which can provide solution to the above mentioned problems.

SUMMARY OF THE INVENTION

The main aspect of the present invention is a fungicidal composition comprising of a) fungicide compound A is Fluxapyroxad or its agrochemically acceptable salts esters and derivatives; b) fungicide compound B strobilurin is selected from Azoxystrobin, Picoxystrobin, Pyraclostrobin, Trifloxystrobin, Metominostrobin or Kresoxim methyl; c) insecticide compound C is selected from Tolfenpyrad, Fluxametamide, Isocycloseram, Broflanilide, Chlorantraniliprole, Cyantraniliprole, Cyclaniliprole, Tetraniliprole, Pioxaniliprole, Methoxyfenozide, Chromafenozide, Tebufenozide, Emamectin benzoate, Indoxacarb or Novaluron ; d) One or more excipients.

Another aspect of the present invention is in addition to active ingredients further comprises inactive formulation excipients including wetting agents, wetting-spreading-penetrating agent, dispersant or dispersing agent, anti-freezing agent, emulsifying agent, anti-foam agent, preservatives, solvents, co-solvents, preservative, stabilizer, diluent, carriers, suspension aid or suspending agent, thickener, and buffering agent.

In further aspect the present invention relates to the fungicidal composition comprising of a) fungicide compound A is in an amount of 4% to 30% w/w of the composition; b) fungicide compound B is in an amount of 4% to 30%w/w of the composition; and c) insecticide compound C is in an amount of 1% to 30% w/w of the composition.

Formulation for the fungicidal composition is selected from Wettable granule/Water dispersible granule (WG/WDG), Suspension concentrate (SC) or Suspo-emulsion (SE).

Further aspect of the present invention provides a method of protecting a plant propagation material, a plant, parts of a plant and/or plant organs that grow at a later point in time against insect-pests damage by applying to the plant propagation material a composition comprising a pesticidal composition defined in the first aspect.

The remainder of the aqueous formulation is preferably wholly water but may comprise other materials, such as inorganic salts. The formulation is completely free from organic solvents.

DETAILED DESCRIPTION OF THE INVENTION:

The present invention relates to a fungicidal composition comprising of a) fungicide compound A Fluxapyroxad or its agrochemically acceptable salts esters and derivatives; b) fungicide compound B strobilurin is selected from Azoxystrobin, Picoxystrobin, Pyraclostrobin, Trifloxystrobin, Metominostrobin or Kresoxim methyl; c) insecticide compound C is selected from Tolfenpyrad, Fluxametamide, Isocycloseram, Broflanilide, Chlorantraniliprole, Cyantraniliprole, Cyclaniliprole, Tetraniliprole, Pioxaniliprole, Methoxyfenozide, Chromafenozide, Tebufenozide, Emamectin benzoate, Indoxacarb or Novaluron; d) One or more inactive excipients.

Another embodiment of the present invention is in addition to active ingredients it further comprises inactive formulation excipients including wetting agents, wetting-spreading-penetrating agent, dispersant or dispersing agent, anti-freezing agent, emulsifying agent, anti-foam agent, preservatives, solvents, co-solvents, preservative, stabilizer, diluent, carriers, suspension aid or suspending agent, thickener, and buffering agent.

Further embodiment of the present invention relates to the fungicidal composition comprising of a) fungicide compound A is in an amount of 4% to 30% w/w of the composition; b) fungicide compound B is in an amount of 4% to 30%w/w of the composition; c) insecticide compound C is in an amount of 1% to 30% w/w of the composition; and d) one or more inactive excipients.

Formulation for the fungicidal composition is selected from Wettable granule/Water dispersible granule (WG/WDG), Suspension concentrate (SC) or Suspo-emulsion (SE).

Fluxapyroxad is a pyrazole-carboxamide fungicide used on a large variety of commercial crops. Fluxapyroxad Molecular formula is C18H12F5N3O.

Fluxapyroxad stunts fungus growth by inhibiting the succinate dehydrogenase (SQR) enzyme. Application of Fluxapyroxad helps prevent many wilts and other fungal infections from taking hold. As with other systemic pesticides that have a long chemical half-life, there are concerns about keeping Fluxapyroxad out of the groundwater, especially when combined with pyraclostrobin. There is also concern that some fungi may develop resistance to Fluxapyroxad.

Fluxapyroxad is succinate dehydrogenase inhibitor (SDHI). It interferes with a number of key fungal life functions, including spore germination, germ tube growth, appresoria formation and mycelium growth. Specifically it interferes with the production of succinate dehydrogenase, the complex II in the mitochondrial respiration chain, which in turn interferes with the tricarboxylic cycle and mitochondrial electron transport. SDHIs are not specific to fungi, they inhibit SDH, the CII of the mitochondrial respiratory chain. As a result, they act on all organisms that have mitochondria.

Further embodiment of the present invention produced a synergistic effect by integrating two fungicides with the insecticides, the formulation offers a wide range of control against insect pests and fungi, while also enhancing plant vigor and yield. Additionally, it provides extended residual control, reducing the frequency of applications needed.

The broad spectrum of the present combination also provides a solution for preventing the development of resistance. The fungicidal composition of specific active ingredient has the special advantage of being highly active against insect-pests and fungi.

Further embodiment of the present invention results in a synergistic action. The combinations of the present invention allow for a broad spectrum of pest control and has surprisingly improved plant vigour and yield. The broad spectrum of the present combination also provides a solution for preventing the development of resistance.

The present compositions are used to protect the crops and plants from fungi, insect and pests. the crops on which the present compositions used, include GMO (Genetically Modified Organism) and Non GMO traits, hybrids and conventional varieties of Cotton (Gossypium spp.), Paddy (Oryza sativa), Wheat (Triticum aestavum), Barley (Hordeum vulgare), Maize (Zea mays), Sorghum (Sorghum bicolor), Oat (Avena sativa), Pearl millet (Pennisetum glaucum), Sugarcane (Saccharum officinarum), Sugarbeet (Beta vulgaris), Soybean (Glycin max), Groundnut/Peanut (Arachis hypogaea), Sunflower (Helianthus annuus), Mustard (Brassica juncea), Rape seed (Brassica napus), Sesame (Sesamum indicum), Green gram (Vigna radiata), Black gram (Vigna mungo), Chickpea (Cicer aritinum), Cowpea (Vigna unguiculata), Red gram (Cajanus cajan), French bean (Phaseolus vulgaris), Indian bean (Lablab purpureus), Horse gram (Macrotyloma uniflorum), Field pea (Pisum sativum), Cluster bean (Cyamopsis tetragonoloba), Lentils (Lens culinaris), Brinjal (Solanum melongena), Cabbage (Brassica oleracea var. capitata), Cauliflower (Brassica oleracea var. botrytis), Okra (Abelmoschus esculentus), Onion (Allium cepa L.), Tomato (Solanum lycopersicun), Potato (Solanum tuberosum), Sweet potato (Ipomoea batatas), Chilli (Capsicum annum), Bell pepper (Capsicum annum), Garlic (Allium sativum), Cucumber (Cucumis sativus), Muskmelons (Cucumis melo), Watermelon (Citrullus lanatus), Bottle gourd (Lagenaria siceraria), Bitter gourd (Momordica charantia), Radish (Raphanus sativus), Carrot (Dacus carota subsp. sativus), Turnip (Brassica rapa rapa), Apple (Melus domestica), Banana (Musa spp.), Citrus groups (Citrus spp.), Grape (Vitis vinifera), Guava (Psidium guajava), Mango (Mangifera indica), Papaya (Carica papaya), Pineapple (Ananas comosus), Pomegranate (Punica granatum), Sapota (Manilkara zapota), Tea (Camellia sinensis), Coffea (Coffea Arabica), Turmeric (Curcuma longa), Ginger (Zingiber officinale), Cumin (Cuminum cyminum), Black Pepper (Piper nigrum), Mentha ( Mentha spp.), Rose (Rosa spp.), Jasmine (Jasminum spp.), Marigold ( Tagetes spp.), Common daisy (Bellis perennis), Dahlia (Dahlia hortnesis), Gerbera ( Gerbera jamesonii), Carnation (Dianthus caryophyllus).

Crops are to be understood as also including those crops which have been rendered tolerant to herbicides or classes of herbicides (e.g. ALS-, GS-, EPSPS-, PPO-, ACCase- and HPPD-inhibitors) by conventional methods of breeding or by genetic engineering. An example of a crop that has been rendered tolerant to imidazolinones, e.g. imazamox, by conventional methods of breeding is summer rape (canola). Examples of crops that have been rendered tolerant to herbicides by genetic engineering methods include e.g. glyphosate- and glufosinate-resistant maize varieties commercially available.

Crops are also to be understood as being those which have been rendered resistant to harmful insects by genetic engineering methods, for example Bt maize (resistant to European corn borer), Bt cotton (resistant to cotton boll weevil) and also Bt potatoes (resistant to Colorado beetle). Examples of Bt maize are the Bt 176 maize hybrids of Syngenta Seeds. The Bt toxin is a protein that is formed naturally by Bacillus thuringiensis soil bacteria. Examples of transgenic plants comprising one or more genes that code for an insecticidal resistance and express one or more toxins are maize, maize, cotton, potatoes. Plant crops or seed material thereof can be both resistant to herbicides and, at the same time, resistant to insect feeding (“stacked” transgenic events). For example, seed can have the ability to express an insecticidal Cry3 protein while at the same time being tolerant to glyphosate.

Other useful plants include turf grass for example in golf-courses, lawns, parks and roadsides, or grown commercially for sod, and ornamental plants such as flowers or bushes. The fungicidal combination of the present invention used to control the insects-pests and fungi.

The major insect-pests are belongs to the order Hemiptera, for example, rice leafhopper/green leaf hopper (GLH) Nephotettix nigropictus, rice brown plant hopper (BPH) Nilaparvata lugen, rice backed plant hopper (WBPH) Sogatella furcifera , Apple Mealy bug Phenococcus aceris, bean aphid Aphis fabae, black citrus aphid Toxoptera aurantii, citrus black scale Saissetia oleae, cabbage aphid Brevicoryne brassicae, Lipaphis erysimi, citrus red scale Aonidiella aurantii, yellow scale Aonidiella citrine, citrus mealybug Planococcus citri, corn leaf aphid Rhopalosiphum maidis, aphid Aphis gossypii, jassid Amrasca biguttula biguttla, mealy bug Planococcus spp. And Pseudococcus spp., cotton stainer Dysdercus suturellus, whitefly Bemisia tabaci, cowpea aphid Aphis crassivora, grain aphid Sitobion avenae, golden glow aphid Uroleucon spp., grape mealybug Pseudococcus maritimus, green peach aphid Myzus persicae, greenhouse whitefly Trialeurodes vaporariorum, papaya mealy bug Pracoccus marginatus, pea aphid Acyrthosiphon pisum, sugarcane mealybug Saccharicoccus sacchari, potato aphid Myzus persicae, potato leaf hopper Empoasca fabae, cotton whitefly Bemisia tabaci, tarnished plant bug Lygus lineolaris, wooly apple aphid Eriosoma lanigerum, mango hopper Amritodus atkinsoni, Idioscopus spp.; order Lepidoptera, army worm Mythimna unipuncta, asiatic rice borer Chilo suppressalis, bean pod borer Maruca vitrata, beet armyworm Spodoptera exigua, black cutworm Agrotis ipsilon, bollworm Helicoverpa armigera , cabbage looper Trichoplusia ni, codling moth Cydia pomonella, croton caterpillar Achea janata, diamond backmoth Plutella xylostella, cabbage worm Pieris rapae, pink bollworm Pectinophora gossypiella, sugarcane borer Diatraea saccharalis, sugarcane early shoot borer Chilo infuscatellus tobacco budworm Heliothis virescens, tomato fruit worm Helicoverpa zea, velvet bean caterpillar Anticarsia gemmatalis, yellow stem borer Scirpophaga incertulas, spotted bollworm Earias vittella, rice leaffolder Cnaphalocrocis medinalis, pink stem borer Sesamia spp., tobacco leafeating caterpillar Spodoptera litura; brinjal fruit and shoot borer Leucinodes orbonalis, bean pod borer Maruca vitrata, Maruca testulalis, armyworm Mythimna separata, cotton pinkbollworm Pectinophora gossypiella, citrus leafminer Phyllocnistis citrella, cabbage butterfly Pieris bras-sicae, diamond backmoth Plutella xylostella, paddy stem borer Scirpophaga excerptallis, Scirpophaga incertulas, Scirpophaga innotata, wheat stem borer Sesamia inferens, Sitotroga cerealella, Spilosoma obliqua, fall armyworm Spodoptera frugiperda, Spodoptera littoralis, Spodoptera litura, Trichoplusia ni, Tryporyza nivella, Tryporyza incertulas, Tuta absoluta.

From the order of Coleoptera, for example, apple twig borer Amphicerus spp., corn root worm Diabrotica virgifera, cucumber beetle diabrotica balteata, boll weevil Anthonomus grandis, grape flea beetle Altica chalybea, grape root worm Fidia viticola, grape trunk borer Clytoleptus albofasciatus, radish flea beetle Phyllotreta armoraciae, maize weevil Sitophilus zeamais, northern corn rootworm Diabrotica barberi, rice water weevil Lissorhoptrus oryzophilus, Anthonomus grandis, Bruchus lentis, Diabrotica semipunctata, Diabrotica virgifera, Dicladispa armigera, Epila-chna varivestis, various species of white grubs are Holotrichia bicolor, Holotrichia consanguinea, Holotrichia serrata, Leptinotarsa decemlineata, Phyllotreta chrysocephala, Popillia japonica etc; from the order Orthoptera, for example, Gryllotalpa spp., Locusta spp., and Schistocerca is spp., from the order Thysanoptera, for example, Frankliniella spp., Thrips palmi, Thrips tabaci, Thrips parvispinus and Scirtothrips dorsalis; termites (Isoptera), e.g. Calotermes flavicollis, Coptotermes formosanus, Heterotermes aureus, Leucotermes flavipes, Microtermes obesi, Odontotermes obesus, Reticulitermes flavipes, Termes natalensis; from the order Heteroptera, for example, Dysdercus spp., Leptocorisa spp., from the order Hymenoptera, for example, Solenopsis spp., from the order Diptera, for example, Antherigona soccata, Dacus spp., Liriomyza spp., Melanagromyza spp.

The major plant parasitic mites are from the order Acarina, for example, Aceria mangiferae, Brevipalpus spp., Eriophyes spp., Oligonychus mangiferus, Oligonychus punicae, Panonychus citri, Panonychus ulmi, Chilli yellow mite-Polyphagotarsonemus latus, Tarsonemus spp., Red spider mite-Tetranychus urticae, Tetranychus cinnabarinus.

The compositions can be employed for controlling diseases caused by phytopathogenic fungi belongs to Ascomycetes, Basidiomycetes, Chytridiomycetes, Deuteromycetes, Oomycetes, Plasmodiophoromycetes, Zygomycetes.

Examples which may be mentioned, but not by limitation, are some pathogens of fungal diseases which come under the above generic terms:

Diseases caused by pathogens causing powdery mildew such as for example, Blumeria species such as for example, Blumeria graminis; Podosphaera species such as for example, Podosphaera leucotricha; Oidium species such as for example Oidium mangiferae, Sphaerotheca species such as for example, Sphaerotheca fuliginea; Uncinula species such as for example, Uncinula necator; Leveillula species such as for example Leveillula taurica, Erysiphe species such as for example Erysiphe polygoni, diseases caused by pathogens of rust diseases such as for example, Gymnosporangium species such as for example, Gymnosporangium sabinae, Hemileia species such as for example, Hemileia vastatrix; Phakopsora species such as for example, Phakopsora pachyrhizi and Phakopsora meibomiae; Puccinia species such as for example, Puccinia graminis, Puccinia recondita or Puccinia triticina, Puccinia striiformis; Uromyces species such as for example, Uromyces phaseoli; diseases caused by pathogens of smut diseases such as for example, Sporisorium species such as for example, Sporisorium scitamineum; Ustilago species such as for example Ustilago maydis, Tilletia species such as for example Tilletia tritici, Ustilaginoidea species such as , for example Ustilaginoidea virens, diseases caused by pathogens of ergot diseases such as for example Claviceps species, Claviceps purpurea; diseases caused by pathogens from the group of the Oomycetes such as for example, Bremia species such as for example, Bremia lactucae; Peronospora species such as for example, Peronospora pisi or P. brassicae; Phytophthora species such as for example, Phytophthora infestans; Plasmopara species such as for example, Plasmopara viticola; Pseudoperonospora species such as for example, Pseudoperonospora humuli or Pseudoperonospora cubensis; Pythium species such as for example, Pythium ultimum; leaf spot diseases and leaf wilt caused by, for example, Alternaria species such as for example, Alternaria solani, Alternaria alternata, Alternaria porii; Cercospora species such as for example, Cercospora arachidicola; Cladiosporum species such as for example, Cladiosporium cucumerinum; Cochliobolus species such as for example, Cochliobolus sativus (conidial form: Drechslera, syn: Helminthosporium);

Colletotrichum species such as for example, Colletotrichum capsici; Cycloconium species such as for example, Cycloconium oleaginum; Diaporthe species such as for example, Diaporthe citri;

Elsinoe species such as for example, Elsinoe fawcettii; Gloeosporium species such as for example, Gloeosporium laeticolor; Glomerella species such as for example, Glomerella cingulata; Guignardia species such as for example, Guignardia bidwelli; Leptosphaeria species such as for example, Leptosphaeria maculans; Magnaporthe species such as for example, Magnaporthe grisea;

Mycosphaerella species such as for example, Mycosphaerella graminicola; Phaeosphaeria species such as for example, Phaeosphaeria nodorum; Pyrenophora species such as for example, Pyrenophora teres;

Ramularia species such as for example, Ramularia collo-cygni; Rhynchosporium species such as for example, Rhynchosporium secalis; Septoria species such as for example, Septoria apii;

Typhula species such as for example, Typhula incarnata; Venturia species such as for example, Venturia inaequalis; root and stalk diseases, caused by, for example, Corticium species such as for example, Corticium graminearum; Fusarium species such as for example, Fusarium oxysporum;

Gaeumannomyces species such as for example, Gaeumannomyces graminis; Rhizoctonia species such as for example, Rhizoctonia solani; Tapesia species such as for example, Tapesia acuformis;

Thielaviopsis species such as for example, Thielaviopsis basicola; ear and panicle diseases (including maize cobs), caused by, for example, Alternaria species such as for example, Alternaria spp;

Aspergillus species such as for example, Aspergillus flavus; Cladosporium species such as for example, Cladosporium spp.; Claviceps species such as for example, Claviceps purpurea;
Fusarium species such as for example, Fusarium culmorum; Gibberella species such as for example, Gibberella zeae; Monographella species such as for example, Monographella nivalis; diseases caused by smuts such as for example, Sphacelotheca species such as for example, Sphacelotheca reiliana;

Tilletia species such as for example, Tilletia caries; Urocystis species such as for example, Urocystis occulta; Ustilago species such as for example, Ustilago nuda; fruit rot caused by, for example, Aspergillus species such as for example, Aspergillus flavus;
Botrytis species such as for example, Botrytis cinerea; Penicillium species such as for example, Penicillium expansum; Sclerotinia species such as for example, Sclerotinia sclerotiorum;

Verticilium species such as for example, Verticilium alboatrum; seed- and soil-borne rots and wilts, and seedling diseases, caused by, for example, Fusarium species such as for example, Fusarium culmorum;

Phytophthora species such as for example, Phytophthora cactorum; Pythium species such as for example, Pythium ultimum; Rhizoctonia species such as for example, Rhizoctonia solani;
Sclerotium species such as for example, Sclerotium rolfsii; cankers, galls and witches' broom diseases, caused by, for example, Nectria species such as for example, Nectria galligena; wilts caused by, for example, Monilinia species such as for example, Monilinia laxa; deformations of leaves, flowers and fruits, caused by, for example, Taphrina species such as for example, Taphrina deformans; degenerative diseases of woody species, caused by, for example, Esca species such as for example, Phaemoniella clamydospora; flower and seed diseases, caused by, for example, Botrytis species such as for example, Botrytis cinerea; diseases of plant tubers caused by, for example, Rhizoctonia species such as for example, Rhizoctonia solani; diseases caused by fungicidal pathogens such as for example, Xanthomonas species such as for example, Xanthomonas campestris pv. oryzae; Pseudomonas species such as for example, Pseudomonas syringae pv. lachrymans; Erwinia species such as for example, Erwinia amylovora.

In an especially preferred embodiment of the invention, the yield of the treated plant is increased.

In another preferred embodiment of the invention, the yield of the plants treated according to the method of the invention, is increased synergistically.

According to the present invention, "increased yield" of a plant, in particular of an agricultural, silvicultural and/or horticultural plant means that the yield of a product of the respective plant is increased by a measurable amount over the yield of the same product of the plant produced under the same conditions, but without the application of the mixture according to the invention.

Increased yield can be characterized, among others, by the following improved proper-ties of the plant: increased plant, weight, increased plant height, increased biomass such as higher overall Fresh Weight (FW), increased number of flowers per plant, higher grain yield, more tillers or side shoots (branches), larger leaves, increased shoot growth, increased protein content, increased oil content, increased starch content, increased pigment content, increased leaf are index.

A further indicator for the condition of the plant is the plant vigor. The plant vigor becomes manifest in several aspects such as the general visual appearance. In another especially preferred embodiment of the invention, the plant vigor of the treated plant is increased. In another preferred embodiment of the invention, the plant vigor of the plants treated according to the method of the invention is increased synergistically. Improved plant vigor can be characterized, among others, by the following improved properties of the plant: improved vitality of the plant, improved plant growth, improved plant development, improved visual appearance, improved plant stand (less plant verse/lodging), improved emergence, enhanced root growth and/or more developed root system, enhanced nodulation, in particular rhizobial nodulation, bigger leaf blade, bigger size, increased plant weight, increased plant height, increased tiller number, increased number of side shoots, increased number of flowers per plant, increased shoot growth, increased root growth (extensive root system), increased yield when grown on poor soils or unfavorable climate, enhanced photosynthetic activity (e.g. based on increased stomatal conductance and/or increased C02 assimilation rate), increased stomatal conductance, increased C02 assimilation rate, enhanced pigment content (e.g. chlorophyll content), earlier flowering, earlier fruiting, earlier and improved germination, earlier grain maturity, improved self-defense mechanisms, improved stress tolerance and resistance of the plants against biotic and abiotic stress factors such as fungi, bacteria, viruses, insects, heat stress, cold stress, drought stress, UV stress and/or salt stress, less non-productive tillers, less dead basal leaves, less input needed (such as fertilizers or water), greener leaves, complete maturation under shortened vegetation periods, less fertilizers needed, less seeds needed, easier harvesting, faster and more uniform ripening, longer shelf-life, longer panicles, delay of senescence, stronger and/or more productive tillers, better extractability of ingredients, improved quality of seeds (for being seeded in the following seasons for seed production), better nitrogen uptake, improved reproduction, reduced production of ethylene and/or the inhibition of its reception by the plant.

The improvement of the plant vigor according to the present invention particularly means that the improvement of any one or several or all of the above mentioned plant characteristics are improved independently of the pesticidal action of the mixture or active ingredients (components).

Further embodiment of the present invention, enhanced quality means that certain plant characteristics such as the content or composition of certain ingredients are increased or improved by a measurable or noticeable amount over the same factor of the plant produced under the same conditions, but without the application of the mixtures of the present invention. Enhanced quality can be characterized, among others, by following improved properties of the plant or its product: increased nutrient content, increased protein content, increased content of fatty acids, increased metabolite content, increased carotenoid content, increased sugar content, increased amount of essential amino acids, improved nutrient composition, improved protein composition, improved composition of fatty acids, improved metabolite composition, improved carotenoid composition, improved sugar composition, improved amino acids composition, improved or optimal fruit color, improved leaf color, higher storage capacity, higher process ability of the harvested products.

Another indicator for the condition of the plant is the plant's tolerance or resistance to biotic and/or abiotic stress factors. Biotic and abiotic stress, especially over longer terms, can have harmful effects on plants. Biotic stress is caused by living organisms while abiotic stress is caused for example by environmental extremes. According to the present invention, "enhanced tolerance or resistance to biotic and/or abiotic stress factors" means (1.) that certain negative factors caused by biotic and/or abiotic stress are diminished in a measurable or noticeable amount as compared to plants exposed to the same conditions, but without being treated with a mixture according to the invention and (2.) that the negative effects are not diminished by a direct action of the mixture according to the invention on the stress factors, e.g. by its fungicidal and insecticidal action which directly destroys the microorganisms or fungi/insects, but rather by a stimulation of the plants' own defensive reactions against said stress factors.

Formulation of the present invention is selected from Wettable granule/Water dispersible granule (WG/WDG), Suspension concentrate (SC) or Suspo-emulsion (SE).

Further composition comprising of a) Fungicide compound A is Fluxapyroxad or its agrochemically acceptable salts esters and derivatives; b) Fungicide compound B strobilurin is selected from Azoxystrobin, Picoxystrobin, Pyraclostrobin, Trifloxystrobin, Metominostrobin or Kresoxim methyl; c) Insecticide compound C is selected from Tolfenpyrad, Fluxametamide, Isocycloseram, Broflanilide, Chlorantraniliprole, Cyantraniliprole, Cyclaniliprole, Tetraniliprole, Pioxaniliprole, Methoxyfenozide, Chromafenozide, Tebufenozide, Emamectin benzoate, Indoxacarb, or Novaluron; and d) one or more inactive excipients.

Further composition comprising of a) Fungicide compound A is Fluxapyroxad or its agrochemically acceptable salts esters and derivatives in an amount of 4% to 30% w/w; b) Fungicide compound B strobilurin is selected from Azoxystrobin, Picoxystrobin, Pyraclostrobin, Trifloxystrobin, Metominostrobin or Kresoxim methyl is present in an amount of 4% to 30% w/w; c) Insecticide compound C is selected from Tolfenpyrad, Fluxametamide, Isocycloseram, Broflanilide, Chlorantraniliprole, Cyantraniliprole, Cyclaniliprole, Tetraniliprole, Pioxaniliprole, Methoxyfenozide, Chromafenozide, Tebufenozide, Emamectin benzoate, Indoxacarb or Novaluron is present in an amount of 1% to 30% w/w ; and d) one or more inactive excipients.

Further embodiment of the present invention relates to the fungicidal composition comprising of a) fungicide compound A is in an amount of 4% to 30% w/w of the composition; b) fungicide compound B is in an amount of 4% to 30% w/w of the composition; and c) insecticide compound C is in an amount of 1% to 30%w/w of the composition.

Composition Compound A Compound B Compound C
Composition Fluxapyroxad Strobilurin fungicides insecticides
% (w/w) 4% to 30%w/w 4% to 30%w/w 1% to 30%w/w

Further embodiment of the present invention includes active ingredients and further comprises inactive formulation excipients including wetting agents, wetting-spreading-penetrating agent, dispersant or dispersing agent, anti-freezing agent, emulsifying agent, anti-foam agent, preservatives, solvents, co-solvents, preservative, stabilizer, diluent, carriers, suspension aid or suspending agent, thickener, and buffering agent.

Dispersing agent for the Wettable Granule (WG) formulation is selected from alkylnaphthalene sulfonate sodium salt, sodium polycarboxylate, naphthalene sulfonic acid, sodium salt condensates with formaldehyde, polyalcoxylated alkylphenol, naphthalene sulfonic acid formaldehyde condensate, methyl naphthalene-formaldehyde-condensate sodium salt, naphthalene condensates, lignosulfonates, polyacrylates and phosphate esters, calcium lignosulfonate, lignin sulfonate sodium salt. EO/PO based copolymer, phenol sulfonate, sodium methyl oleoyl taurate, styrene acrylic acid copolymer, propylene oxide-ethylene oxide-copolymer, polyethylene glycol 2, 4, 6-tristyrylphenyl ether, tristyrylphenol-polyglycol ether-phosphate, tristyrylphenole with 16 moles EO, oleyl-polyglycol ether with ethylene oxide, tallow fatty amine polyethylene oxide, nonylphenol polyglycol ether with 9-10 moles ethylene oxide or mixture thereof is present in the amount of 1% to 20% w/w.

The combination of Dispersing agents creates synergistic effects that enhance stability. Combination of dispersing agents, along with the fungicide and insecticide compounds ensures stability and uniformity of mixtures by preventing particle agglomeration and settling. They also improve flow properties, making the product easier to handle and apply, and ensure consistent performance by promoting even distribution of active ingredients.

Wetting agent for the Wettable Granule (WG) formulation is selected from sodium N-methyl-N-oleoyl taurate, alkylated naphthalene sulfonate, sodium salt, mixture of isomers of dibutyl naphthalene sulphonic acid sodium salt, sodium di-isopropyl naphthalene sulphonate, sodium Lauryl sulfate, dioctyl sulfate, alkyl naphthalene sulfonates, phosphate esters, sulphosuccinates and non-ionic such as tridecyl alcohol ethoxylate, alkyl or alkaryl sulfonates such as alkylbenzene sulfonates, alpha olefin sulfonate and alkyl naphthalene sulfonates, ethoxylated or non-ethoxylated alkyl or alkaryl carboxylates, alkyl or alkaryl phosphate esters, alkyl polysaccharide, di or mono alkyl sulfosuccinate derivatives, alpha olefin sulfonates, alkyl naphthalene sulfonates, dialkyl sulphosuccinates, butyl, dibutyl, isopropyl and di-isopropyl naphthalene sulfonate salts, C12 alkyl benzene sulfonate or C10-C16 alkyl benzene sulfonate, organosilicons surfactants includes trisiloxane ethoxylate, polydimethylsiloxane, polyoxyethylene methyl polysiloxane, polyoxyalkylene methyl polysiloxane, polyether polymethyl siloxane copolymer, trisiloxane heptamethyl, Polyalkyleneoxide modified heptamethyl trisiloxane, polyether modified polysiloxane, may or may not be in modified form, may be liquid or powder form or mixture thereof is present in the amount of 1% to 10% w/w.

Antifoaming agent for the Wettable Granule (WG) formulation is selected from silicone oil, silicone compound, C10~C20 saturated fat acid compounds or C8~C10 aliphatic alcohols compound, silicone antifoam emulsion, dimethyl siloxane, polydimethyl siloxane, vegetable oil based antifoam, tallow based fatty acids, polyalkyleneoxide modified polydimethylsiloxane or mixture thereof is present in the amount of 0.5% to 2% w/w.

Carrier for the Wettable Granule (WG) formulation is selected from china clay, silica, lactose anhydrous, ammonium sulfate, sodium sulfate anhydrous fertilizers such as urea, corn starch, urea, EDTA, urea formaldehyde resin, diatomaceous earth, kaolin, bentonite, kieselguhr, fuller's earth, attapulgite clay, bole, loess, talc, chalk, dolomite, limestone, lime, calcium carbonate, powdered magnesia, magnesium oxide, magnesium sulphate, sodium chloride, gypsum, calcium sulphate, pyrophyllite, silicates and silica gels; fertilizers such as, for example, ammonium sulphate, ammonium phosphate, ammonium nitrate and urea; natural products of vegetable origin such as, for example, grain meals and flours, bark meals, wood meals, nutshell meals and cellulosic powders; and synthetic polymeric materials such as, for example, ground or powdered plastics and resins, bentonites, zeolites, titanium dioxide, iron oxides and hydroxides, aluminium oxides and hydroxides, or organic materials such as bagasse, charcoal, or synthetic organic polymers or mixture thereof.

Wetting-spreading-penetrating agent for the Suspension Concentrate (SC) formulation is selected from trisiloxane ethoxylate, heptamethyl trisiloxane, modified form includes polyalkyleneoxide modified heptamethyl trisiloxane, polyether modified polysiloxane, polyalkyleneoxide modified trisiloxane, polyalkyleneoxide modified polydimethylsiloxane, may be liquid or powder form is present in the amount of 1% to 10% w/w.

Wetting-spreading-penetrating agent improves liquid interaction with surfaces by reducing surface tension, which facilitates better spreading. As a result, it enhances coverage and adherence of the formulation to the target area.

Dispersing agent for Suspension Concentrate (SC) formulation is selected from Naphthalenesulfonic acid, sodium salt condensate with formaldehyde, alkylated naphthalene sulfonate, sodium salt, sodium salt of naphthalene sulfonate condensate, sodium ligno sulfonate, and sodium polycarboxylate. EO/PO based copolymer, phenol sulfonate, sodium methyl oleoyl taurate, styrene acrylic acid copolymer, propylene oxide-ethylene oxide-copolymer, polyethylene glycol 2,4,6-tristyrylphenyl ether, tristyrylphenol-polyglycol ether-phosphate, tristyrylphenole with 16 moles EO, tristyrylphenol-polyglycol ether-phosphate, oleyl-polyglycol ether with ethylene oxide, tallow fatty amine polyethylene oxide, nonylphenol polyglycol ether with 9-10 moles ethylene oxide is present in the amount of 1% to 10% w/w.

Suspending agent for the Suspension Concentrate (SC) formulation is selected from aluminum magnesium silicate, bentonite clay, silica, attapulgite clay is present in the amount of 0.25 to 2% w/w. Suspending agent ensures solid particles evenly distributed in a liquid medium, preventing settling and enhancing product stability.

Antifoaming agent for the Suspension Concentrate (SC) formulation is selected from silicone antifoam emulsion, dimethyl siloxane, polydimethyl siloxane, vegetable oil based antifoam, and tallow based fatty acids is present in the amount of 0.1% to 2% w/w.

Anti-freezing agent for the Suspension Concentrate (SC) formulation is selected from ethylene glycol, propane diols, glycerin or the urea, glycol (monoethylene glycol, diethylene glycol, polypropylene glycol, and polyethylene glycol), glycerin, urea, magnesium sulfate heptahydrate, sodium chloride is present in the amount of 0.1% to 1% w/w.

Preservatives for the Suspension Concentrate (SC) formulation is selected from 1, 2-benzisothiazolin-3(2H)-one, sodium salt, sodium benzoate, 2-bromo-2-nitropropane-1, 3-diol, formaldehyde, sodium o-phenyl phenate, 5-chloro-2-methyl-4-isothiazolin-3-one & 2-methyl-4-isothiazolin-3-one or mixture thereof.

Thickeners for the Suspension Concentrate (SC) formulation is selected from xanthan gum, PVK, carboxymethyl celluloses, polyvinyl alcohols, gelatin, sodium carboxymethylcellulose, hydroxyethyl cellulose, sodium polyacrylate, modified starch, acacia gum or there mixture thereof.

Solvent for the Suspension Concentrate (SC) formulation is selected from and not limited demineralized (DM) water, alcohols such as ethanol, propanol, n-octanol, isopropanol ethylene glycol, diethylene glycol, propylene glycol, polyethylene glycol, glycerine, polyol ethers such as ethylene glycol monopropyl ether, diethylene glycol, monomethyl ether, dipropylene glycol dimethyl ether; ketones such as acetone, methyl ethyl ketone, methyl isobutyl ketone, cyclohexanone; ethers such as dipropylether, dioxane, tetrahydrofuran or there mixture thereof.

Emulsifier for the Suspo Emulsion (SE) formulation is selected from salts of dodecylbenzene sulphonate, e.g. Ca-salts or amine salts, and sulphonates of other C11-C16 alkylbenzenes, alkylether sulphates, alkylphenoletherphosphates and ester phosphates; non-ionic surfactants such as alkoxylated alcohols and alkylphenols, ethoxylated fatty acids, ethoxylated vegetable oils, e.g. ethoxylated castor oil, fatty acid esters, e.g. of sorbitol, and their ethoxylated derivatives, ethoxylated amines, and condensates of glycerol; and catanionic emulsifiers such as a cationic amine, optionally in combination with an alkylsulphonate or ether sulphonate or ether phosphate, alkoxylated alcohols; alkoxylated alkylphenols; ethoxylated fatty acids; ethoxylated vegetable oils; ethoxylated tristyrylphenol (tristyrlphenol with 16 moles EO), tristyrylphenol-polyglycolether-phosphate, fatty acid esters of sorbitol and ethoxylated derivatives thereof; ethoxylated amines and condensates of glycerol; sulfonated alkylbenzenes in the range C11-C16 and salts thereof; alkylether sulphates; alkyletherphosphates; alkylphenoletherphosphates; or combinations thereof; salts of phosphate esters of ethoxylated tristyrylphenol; salts of sulphated ethers of ethoxylated tristyrylphenol; or a catanionic system, wherein a cationic amine is present in combination with an alkylsulphonate, an alkylethersulphonate, an ether sulphate, or an ether phosphate such as an alkyletherphosphate, nonylphenol polyethoxy ethanols, castor oil polyglycol ethers, polyadducts of ethylene oxide and polypropylene, tributyl phenoxy polyethoxy ethanol, octyl phenoxy polyethoxy ethanol to ensure stabilization of mixtures of immiscible liquids, such as oil and water, by reducing surface tension and promoting a uniform dispersion present in an amount of 1% to 10% w/w.

Solvent for the Suspo Emulsion (SE) formulation is selected from Hyrdocarbons includes n-pentane, hexane(s), cyclohexane, methylcyclohexane, heptane, isooctane, benzene, toluene, xylene(s), isophorone and ester solvents such as methyloleate, dimethylamide and morpholineamide derivatives of C6-C16 fatty acids, and mono-alkylene carbonates such as ethylene carbonate, propylene carbonate and butylene carbonates, dimethylsulfoxide (DMSO), 2-ethylhexanol and n-butanol, n-alkylpyrrolidones, fatty acid dimethyl esters, fatty acid esters, dibasic esters, aromatic hydrocarbons and/or aliphatic hydrocarbons, one or more dimethylamides, such as C8-dimethylamide, C10-dimethylamide, C12-dimethylamide, ethylene glycol, propylene glycol, polyalkylene glycols, aromatic hydrocarbons, methylpyrrolidinone (NMP); dimethylformamide (DMF); dimethylisosorbide (DMI); isophorone; acetophenone; 1,3-dimethyl-2-imidazolidonone; lactate esters; dimethyl and diethylcarbonates; alcohols including methanol; ethanol; iso-propanol; n-propanol; n-butanol; iso-butanol; and tert-butanol; Methyl L-lactate, 2-Ethylhexyl L-lactate, Ethyl L-lactate, n-Butyl L-lactate, Octyl phenol ethoxylates, water, water soluble alcohols and dihydroxy alcohol ethers. Water soluble alcohol or lower alcohol (1-4 carbon atoms) includes-methanol, ethanol, n-propanol, isopropanol, n-butanol, tert-butanol or there mixture thereof.

Dispersing agent for the Suspo Emulsion (SE) formulation is selected from polyesters, polyamides, poly- carbonates, polyurea and polyurethanes, acrylic polymers, acrylic graft copolymer, styrene copolymers, butadiene copolymers, polysaccharides such as starch and cellulose derivatives, vinylalcohol, vinylacetate and vinylpyrrolidone polymers and copolymers, polyethers, epoxy, phenolic and melamine resins, polyolefins and define copolymers and mixtures thereof. Examples of preferred polymers are acrylate polymers such as poly(methacrylate), poly(ethyl methacrylate), poly(methylmethacrylate), acrylate copoylmers and styrene-acrylic copolymers as defined herein below, poly(styrene-co maleic anhydride), cellulosic polymers such as ethyl cellulose, cellulose acetate, cellulose acetatebutyrate, acetylated mono, di, and triglycerides, poly(vinylpyrrolidone), vinyl acetate polymers and copolymers, poly(alkylene glycol), styrene butadiene copolymers, poly(orthoesters), alkyd resins, biodegradable polyesters, starch, polylactic acid starch blends, polylactic acid, poly(lactic acid-glycolic acid) copolymers, polydioxanone, cellulose esters, ethyl cellulose, cellulose acetate butyrate, starch esters, starch esteraliphatic polyester blends, modified corn starch, polycaprolactone, poly(namylmethacrylate), wood rosin, polyanhydrides, polyvinylalcohol, polyhydroxybutyratevalerate, biodegradable aliphatic polyesters, and polyhydroxybutyrate or mixtures thereof. The examples of dispersing agents are alkylated naphthalene sulfonate, sodium salt, sodium salt of naphthalene sulfonate condensate, sodium salt of alkyl naphthalene sulfonate, sodium ligno sulfonate, sodium ploycarboxylate, EO/PO block copolymer, phenol sulfonate, sodium methyl oleoyl taurate, styrene acrylic acid copolymer, propyleneoxide-ethyleneoxide-copolymer, polyethylene glycol 2,4,6-tristyrylphenyl ether, tristyrylphenol-polyglycolether-phosphate, tristyrylphenole with 16 moles EO, tristyrylphenol-polyglycolether-phosphate, oleyl-polyglycolether with ethylene oxide, tallow fatty amine polyethylene oxide, nonylphenol polyglycolether with 9-10 moles ethylene oxide or there mixture thereof is present in an amount of 1% to 20% w/w.

Suspending agent for the Suspo Emulsion (SE) formulation is selected from aluminum magnesium silicate, bentonite clay, silica, silicone dioxide, attapulgite clay or mixture thereof is present in the amount of 0.25% to 2%w/w.

Anti-foaming agent for the Suspo Emulsion (SE) formulation is selected from silicone oil, silicone compound, C10~C20 saturated fat acid compounds or C8~C10 aliphatic alcohols compound, silicone antifoam emulsion, dimethylsiloxane, polydimethyl siloxane, vegetable oil based antifoam, tallow based fatty acids, polyalkyleneoxide modified polydimethylsiloxane or a mixture of thereof.

Preservative for the Suspo Emulsion (SE) formulation is selected from propionic acid and its sodium salt, sorbic acid and its sodium or potassium salt, benzoic acid and its sodium salt, p-hydroxy benzoic acid sodium salt; methyl p-hydroxy benzoate; and biocide such as sodium benzoate, 1,2-benzisothiazoline-3-one, 2-methyl-4-isothiazolin-3-one, 5-chloro-2- methyl-4-isothiazolin-3-one, potassium sorbate, para hydroxy benzoates or mixtures thereof.

Anti –freezing agent for the Suspo Emulsion (SE) formulation is selected from ethylene glycol, propane diols, glycerine or the urea, glycol (monoethylene glycol, diethylene glycol, polypropylene glycol, polyethylene glycol), glycerine, urea, magnesium sulphate heptahydrate, sodium chloride or mixture thereof.

Thickner for the Suspo Emulsion (SE) formulation is selected from guar gum; locust bean gum; carrageenam; xanthan gum; alginates; methyl cellulose; sodium carboxymethyl cellulose (SCMC); hydroxyethyl cellulose (HEC) or mixtures thereof. Other types of anti-settling agents are based on modified starches, polyacrylates, polyvinyl alcohol and polyethylene oxide or mixtures.

The fungicidal composition comprising of a) fungicide compound A is Fluxapyroxad or its agrochemically acceptable salts esters and derivatives and is present in an amount of 4% to 30% w/w of the composition; b) fungicide compound B is selected from Azoxystrobin, Picoxystrobin, Pyraclostrobin, Trifloxystrobin, Metominostrobin, Kresoxim methyl and is present in an amount of 4% to 30% w/w of the composition; and c) insecticide compound C is selected from Tolfenpyrad, Fluxametamide, Isocycloseram, Broflanilide, Chlorantraniliprole, Cyantraniliprole, Cyclaniliprole, Tetraniliprole, Pioxaniliprole, Methoxyfenozide, Chromafenozide, Tebufenozide, Emamectin benzoate, Indoxacarb, Novaluron and is present in an amount of 1% to 30% w/w.

The ternary fungicidal composition provides following benefits;
• Synergistic control (grams of active ingredients required less to achieve desired level of control).
• Broad spectrum control of fungal diseases and insect-pests (caterpillars, sucking pests, mites) with one shot application.
• Residual control i.e., longer duration of control with immediate crop protection.
• Delay in development of resistance and effective control of difficult to manage diseases and hard to kill insect-pests.
• Increase in yield of treated plants (vegetables, cereals, pulses, oilseeds, fiber crop, sugar crops, tuber crops, fruit crops, flowers, ornamentals etc.)
• Increase in yield due to protection against diseases and insect-pests.
• Increase in yield due to a greater number of tillers, more branches and subbranches, a greater number of flowers, and a greater number of fruits.
• Increase plant vigor.
• Increase tolerance to abiotic stress.

The process for preparing the present novel fungicidal composition can be modified accordingly by any person skilled in the art based on the knowledge of the manufacturing the formulation. However, all such variation and modification is still covered by the scope of present invention.

Example 1: Composition of Fluxapyroxad 10%+Pyraclostrobin 18%+Tolfenpyrad 16% WG
Chemical composition content (% w/w) content (% w/w) content (% w/w) content (% w/w)
Fluxapyroxad a.i. 10.00 9.50 10.5 9.5 to 10.5
Pyraclostrobin a.i. 18.00 17.10 18.9 17.1 to 18.9
Tolfenpyrad a.i. 16.00 15.20 16.8 15.2 to 16.8
Modified Sodium lignosulphonate (dispersing agent) 7.00 7.00 7.00 7.00
Modified polyacrylate copolymer (dispersing agent ) 3.00 3.00 3.00 3.00
Sodium isopropyl naphthalene sulfonate (wetting agent) 5.00 5.00 5.00 5.00
Polydimethylsiloxane (Antifoaming Agent) 1.00 1.00 1.00 1.00
Corn Starch (carrier) 15.00 15.00 15.00 15.00
China clay (carrier ) 25.00 27.20 22.80 69.00
Total 100.00 100.00 100.00 100.00
a.i. (active ingredient) on 100% purity basis

Storage Stability: Fluxapyroxad 10%+Pyraclostrobin 18%+Tolfenpyrad 16% WG
Laboratory storage stability for 14 days
Parameters Specification Initial At 54±2 0C At 0±2 0C
Fluxapyroxad a.i. 9.5 to 10.5 10.38 10.31 10.37
Pyraclostrobin a.i. 17.1 to 18.9 18.41 18.37 18.4
Tolfenpyrad a.i. 15.2 to 16.8 16.29 16.23 16.25
Compound A suspensibility (%) 70 89.78 85.98 88.36
Pyraclostrobin suspensibility (%) 70 91.23 89.45 90.12
Tolfenpyrad suspensibility (%) 70 87.87 84.91 87.12
pH range (1% aq. Suspension) 5 to 9 8.25 8.27 8.24
Particle size (micron) D90<10 8.3 8.5 8.2
Persistent foam ml (after 1 minute) max. 60 20 25 22

Room temperature storage stability up to 12 months
Parameters Specification Initial 1 month 6 month 12 month
Fluxapyroxad a.i. 9.5 to 10.5 10.38 10.37 10.35 10.33
Pyraclostrobin a.i. 17.1 to 18.9 18.41 18.39 18.35 18.31
Tolfenpyrad a.i. 15.2 to 16.8 16.29 16.28 16.26 16.21
Fluxapyroxad suspensibility (%) 70 89.78 89.75 89.71 89.68
Pyraclostrobin suspensibility (%) 70 91.23 91.21 91.15 91.01
Tolfenpyrad suspensibility (%) 70 87.87 87.82 87.79 87.54
pH range (1% aq. Suspension) 5 to 9 8.25 8.27 8.26 8.28
Particle size (micron) D90<10 8.3 8.34 8.32 8.35
Persistent foam ml (after 1 minute) max. 60 20 20 25 25

The composition of Fluxapyroxad 10%+Pyraclostrobin 18%+Tolfenpyrad 16% WG meets the all inhouse specifications for storage stability studies in laboratory (at 54±2 C & at 0±2 C for 14 days) and room temperature (for 12 months).

Procedure: Manufacturing process for 100 kg batch of Fluxapyroxad 10%+Pyraclostrobin 18%+Tolfenpyrad 16% WG
Step 1: Charge the 25 kg China clay, 15.0 kg Corn starch, 0.5 kg silicone antifoam, 5 kg of Sodium isopropyl naphthalene sulfonate, 3 kg Modified polyacrylate copolymer and 7.0 kg of Modified Sodium lignosulphonate blend into a ribbon or premix blender and homogenization for 30 minutes.
Step 2: Now charge 10.0 kg Fluxapyroxad technical, 18 kg Pyraclostrobin technical and 16 kg Tolfenpyrad technical and again homogenize for 30 minutes and now this Pre-blended material is then grinded through Jet mill/ air classifier mills. Finely grinded material is blended in post blender till it becomes homogeneous. (for approx 1.5 hr)
Step 3: Finely grinded powder is mixed with 10 kg of water having 0.5 kg silicone antifoam to form extrudable dough.
Step 4: Dough is passed through extruder to get granules of required size.
Step 5: Wet granules are passed through Fluidized bed drier to remove 10 kg extra water added and further graded using vibrating screens.
Step 6: Final product is sent for QC approval.
Step 7: After approval material is packed in required pack sizes.

Example 2: Composition of Fluxapyroxad 10%+Azoxystrobin 15%+Chlorantraniliprole 8% SC

Chemical composition content (% w/w) content (% w/w) content (% w/w) content (% w/w)
Fluxapyroxad a.i. 10.00 9.50 10.5 9.5 to 10.5
Azoxystrobin a.i. 15.00 14.25 15.75 14.25 to 15.75
Chlorantraniliprole a.i. 8.00 7.60 8.8 7.6 to 8.8
Methylated seed oil, polyalkyleneoxide modified trisiloxane (super wetting-spreading-penetrating agent) 5.00 5.00 5.00 5.00
Ethylene-propylene oxide block copolymer (dispersing agent) 4.75 4.75 4.75 4.75
Sodium naphthalene sulphonate formaldehyde condensates (dispersing agent) 1.25 1.25 1.25 1.25
Aluminum magnesium silicate (suspending agent) 0.50 0.50 0.50 0.50
Polydimethylsiloxane (anti foaming agent) 0.30 0.30 0.30 0.30
Sodium benzoate (preservative) 0.20 0.20 0.20 0.20
Polypropylene glycol (anti-freezing agent) 5.00 5.00 5.00 5.00
Xanthan gum (thickener) 0.20 0.20 0.20 0.20
Diluent water (solvent) 49.80 51.45 47.75 82.80
Total 100.00 100.00 100.00 100.00

Storage Stability: Fluxapyroxad 10%+Azoxystrobin 15%+Chlorantraniliprole 8%
Laboratory storage stability for 14 days
Parameters Specification Initial At 54±2 0C At 0±2 0C
Fluxapyroxad a.i. 9.5 to 10.5 10.38 10.24 10.35
Azoxystrobin a.i. 14.25 to 15.75 15.66 15.52 15.63
Chlorantraniliprole a.i. 7.6 to 8.8 8.44 8.34 8.42
Fluxapyroxad suspensibility (%) 80 98.70 98.15 98.60
Azoxystrobin suspensibility (%) 80 98.50 98.20 98.35
Chlorantraniliprole suspensibility (%) 80 98.60 98.25 98.50
pH range (1% aq. Suspension) 5.5 to 8.0 7.05 7.15 7.05
Pourability (%) 95 98.40 98.10 98.20
Specific gravity 1.05-1.10 1.07 1.07 1.07
Viscosity at spindle no.62,20 rpm 350-800 cps 530 550 550
Particle size (micron) D50<3, D90<10 2.1,8.5 2.1,8.7 2.1,8.7
Persistent foam ml (after 1 minute) max. 60 nil nil nil

Room temperature storage stability up to 12 months
Parameters Specification Initial 1 month 6 month 12 month
Fluxapyroxad a.i. 9.5 to 10.5 10.38 10.38 10.36 10.35
Azoxystrobin a.i. 14.25 to 15.75 15.66 15.66 15.64 15.63
Chlorantraniliprole a.i. 7.6 to 8.8 8.44 8.44 8.43 8.42
Fluxapyroxad suspensibility (%) 80 98.70 98.70 98.60 98.50
Azoxystrobin suspensibility (%) 80 98.50 98.50 98.35 98.30
Chlorantraniliprole suspensibility (%) 80 98.60 98.60 98.50 98.40
pH range (1% aq. Suspension) 5.5 to 8.0 7.05 7.05 7.06 7.10
Pourability (%) 95 98.20 98.20 98.20 98.10
Specific gravity 1.05-1.10 1.07 1.07 1.07 1.07
Viscosity at spindle no. 62, 20 rpm 350-800 cps 530 530 530 535
Particle size (micron) D50<3, D90<10 2.1,8.5 2.1,8.5 2.1,8.5 2.1,8.6
Persistent foam in ml (after 1 minute) max. 60 nil nil nil nil

The composition of Fluxapyroxad 10%+Azoxystrobin 15%+Chlorantraniliprole 8% SC meets the all inhouse specifications for storage stability studies in laboratory (at 54±2 C & at 0±2 C for 14 days) and room temperature (for 12 months).

Procedure: Manufacturing process for 100 kg batch ofFluxapyroxad 10%+Azoxystrobin 15%+Chlorantraniliprole 8% SC
Step 1: Preparation of 2% Gum Solution: Charge Xanthan gum (2.0 kg) and Sodium benzoate (2.0 kg) into 96.0 kg water and homogenize. It should be made 12 to 18 hours prior to use.
Step 2: Charge DM water (39.8 kg) and 1, 2-propylene glycol (5 kg) into designated vessel and ix thoroughly.
Step 3: Step 3: Add Sodium naphthalene sulphonate formaldehyde condensates (1.25 kg), Ethylene-propylene oxide block copolymer (4.75 kg) and Aluminum magnesium silicate (0.5 kg) into the vessel having water and homogenise the contents for 45 to 60 minutes using high shear homogeniser.
Step 4: Then add Fluxapyroxad technical (10 kg), Azoxystrobin technical (15 kg) and Chlorantraniliprole technical (8 kg) to this premix slowly and homogenised to get uniform slurry ready for grinding.
Step 5: Before grinding half the quantity of Polydimethylsiloxane (0.15 kg) was added and then material was subjected to grinding in Dyno mill till desired particle size is achieved.
Step 6: Add remaining Polydimethyl siloxane (0.15 kg) antifoam was added after grinding process completes and before sampling for in process analysis.
Step 7: Add 10 kg of 2% Gum solution and 5 kg of Methylated seed oil, polyalkyleneoxide modified trisiloxane. Now send this final formulation to QC for quality check.

Example 3: Composition of Fluxapyroxad 4%+Trifloxystrobin 8%+Novaluron 7.5%
Chemical composition content (% w/w) content (% w/w) content (% w/w) content (% w/w)
Fluxapyroxad a.i. 4.00 3.80 4.4 3.80 to 4.40
Trifloxystrobin a.i. 8.00 7.60 8.8 7.60 to 8.8
Novaluron a.i. 7.50 7.13 8.25 7.13 to 8.25
Polyarylphenyl anionic ether sulfate, ammonium salt (Emulsifier) 1.50 1.50 1.50 1.50
Aromatic solvent C-9 (solvent) 10.00 10.00 10.00 10.00
Acrylic graft copolymer (dispersing agent 1) 3.00 3.00 3.00 3.00
Butyl Polyalkylene Oxide block copolymer (dispersing agent ) 4.50 4.50 4.50 4.50
Aluminum magnesium silicate (suspending agent) 0.50 0.50 0.50 0.50
Polydimethylsiloxane (anti foaming agent) 0.20 0.20 0.20 0.20
1,2-benzisothiazolin-3(2H)-one (preservative) 0.15 0.15 0.15 0.15
1,2-propylene glycol (anti freezing agent) 5.00 5.00 5.00 5.00
Xanthan gum (thickener) 0.15 0.15 0.15 0.15
Diluent water (solvent) 55.50 56.48 53.55 75.00
Total 100.00 100.00 100.00 100.00
a.i. (active ingredient) on 100% purity basis

Storage Stability: Fluxapyroxad 4%+Trifloxystrobin 8%+Novaluron 7.5% SE
Laboratory storage stability for 14 days
Parameters Specification Initial At 54±2 0C At 0±2 0C
Fluxapyroxad a.i. 3.80 to 4.40 4.21 4.19 4.21
Trifloxystrobin a.i. 7.60 to 8.8 8.32 8.31 8.32
Novaluron a.i. 7.13 to 8.25 7.75 7.72 7.75
Fluxapyroxad suspensibility (%) 80 98.45 98.39 98.46
Trifloxystrobin suspensibility (%) 80 98.75 98.71 98.75
Novaluron suspensibility (%) 80 98.42 98.40 98.41
pH range (1% aq. Suspension) 5.5 to 8.5 7.06 7.09 7.07
Pourability (%) 95 98.51 98.11 98.49
Specific gravity 1.05-1.10 1.06 1.06 1.06
Viscosity at spindle no.62,20 rpm 350-800 cps 532 549 539
Particle size (micron) D50<3, D90<10 2.1,8.4 2.1,8.6 2.1,8.5
Persistent foam ml (after 1 minute) max. 60 nil nil nil

Room temperature storage stability up to 12 months
Parameters Specification Initial 1 month 6 month 12 month
Fluxapyroxad a.i. 3.80 to 4.40 4.21 4.21 4.2 4.15
Trifloxystrobin a.i. 7.60 to 8.8 8.32 8.31 8.29 8.27
Novaluron a.i. 7.13 to 8.25 7.75 7.75 7.74 7.69
Fluxapyroxad suspensibility (%) 80 98.45 98.44 98.42 98.39
Trifloxystrobin suspensibility (%) 80 98.75 98.74 98.72 98.68
Novaluron suspensibility (%) 80 98.42 98.40 98.39 98.35
pH range (1% aq. Suspension) 5.5 to 8.5 7.06 7.05 7.11 7.14
Pourability (%) 95 98.51 98.49 98.47 98.43
Specific gravity 1.05-1.10 1.06 1.06 1.06 1.06
Viscosity at spindle no. 62, 20 rpm 350-800 cps 532 533 536 542
Particle size (micron) D50<3, D90<10 2.1,8.4 2.1,8.5 2.1,8.5 2.1,8.6
Persistent foam in ml (after 1 minute) max. 60 nil nil nil nil

Procedure: Manufacturing process for 100 kg batch of Fluxapyroxad 4%+Trifloxystrobin 8%+Novaluron 7.5% SE

Step 1: Preparation of 2% Gum solution: Charge Xanthan gum (2 kg) and 1, 2-benzisothiazoline-3-one (2 kg) into 96 kg water and homogenizeand should be made 12 to 18 hours prior to use.
Step 2: EC premix- Add Aromatic solvent C-9 (10 kg) into other vessel having slow stirring. Now addFluxapyroxad technical (4 kg) and Butyl Polyalkylene Oxide block copolymer (4.5 kg) and mix properly for 30 to 45 minutes.
Step 3: Charge DM water (52.25 kg) and 1, 2-propylene glycol (5 kg) into designated vessel and mix thoroughly.
Step 4:
Add Aluminum magnesium silicate (0.5 kg), Acrylic graft copolymer (3 kg), Polyarylphenyl anionic ether sulfate, ammonium salt (1.5 kg) and Polydimethylsiloxane (0.1 kg) into the vessel having water and homogenise the contents for 45 to 60 minutes using high shear homogeniser.
Step 5: Then add Trifloxystrobin technical (8 kg) and Novaluron technical (7.50 kg) to this premix slowly and homogenised to get uniform slurry ready for grinding.
Step 6: Before grinding, Polydimethylsiloxane (0.1 kg) was added and then material was subjected to grinding in Dyno mill till desired particle size is achieved.
Step 7: Add remaining Polydimethyl siloxane antifoam (0.1 kg) was added after grinding process completes and before sampling for in process analysis.
Step 8: Now mix EC premix to this milled slurry under slow stirring and homogenize for 30-45 minutes
Step 9: Finally add 2% gum solution (7.5 kg) to this formulation and send to QC for quality check.

Lists of present compositions

Compound A Fungicide Compound B-Strobilurin Insecticide Compound C- active ingredients(%) of compound Formulation Strength (%) Formulation
A B C
Fluxapyroxad Pyraclostrobin Tolfenpyrad 10 18 16 44.00 WG
Fluxapyroxad Trifloxystrobin Tolfenpyrad 10 18 16 44.00 WG
Fluxapyroxad Azoxystrobin Tolfenpyrad 7.5 7.5 10 25.00 SC
Fluxapyroxad Picoxystrobin Tolfenpyrad 7.5 7.5 10 25.00 SC
Fluxapyroxad Pyraclostrobin Fluxametamide 7.5 10 5 22.50 WG
Fluxapyroxad Pyraclostrobin Isocycloseram 7.5 10 7.5 25.00 SC
Fluxapyroxad Pyraclostrobin Broflanilide 12 16 5 33.00 SC
Fluxapyroxad Pyraclostrobin Chlorantraniliprole 10 16 8 34.00 SC
Fluxapyroxad Pyraclostrobin Cyantraniliprole 10 16 12 38.00 WG
Fluxapyroxad Pyraclostrobin Cyclaniliprole 5 8 4 17.00 SE
Fluxapyroxad Pyraclostrobin Tetraniliprole 6.67 10.66 5.33 22.66 WG
Fluxapyroxad Pyraclostrobin Methoxyfenozide 3.2 6.4 16 25.60 SC
Fluxapyroxad Pyraclostrobin Emamectin benzoate 4 8 1.2 13.20 SC
Fluxapyroxad Pyraclostrobin Indoxacarb 4 8 7.5 19.50 SC
Fluxapyroxad Pyraclostrobin Novaluron 4 8 7.5 19.50 SE
Fluxapyroxad Pyraclostrobin Chromafenozide 12 16 16 44.00 WG
Fluxapyroxad Pyraclostrobin Tebufenozide 12 16 16 44.00 WG
Fluxapyroxad Azoxystrobin Fluxametamide 10 15 8 33.00 SE
Fluxapyroxad Azoxystrobin Isocycloseram 10 15 12 37.00 SC
Fluxapyroxad Azoxystrobin Broflanilide 10 15 5 30.00 SC
Fluxapyroxad Azoxystrobin Chlorantraniliprole 10 15 8 33.00 SC
Fluxapyroxad Azoxystrobin Cyantraniliprole 10 15 12 37.00 SC
Fluxapyroxad Azoxystrobin Cyclaniliprole 5 7.5 4 16.50 SE
Fluxapyroxad Azoxystrobin Tetraniliprole 6.67 10 5.33 22.00 SC
Fluxapyroxad Azoxystrobin Methoxyfenozide 3.2 6.4 16 25.60 SC
Fluxapyroxad Azoxystrobin Emamectin benzoate 4 8 1.2 13.20 SC
Fluxapyroxad Azoxystrobin Indoxacarb 4 8 7.5 19.50 SC
Fluxapyroxad Azoxystrobin Novaluron 4 8 7.5 19.50 SE
Fluxapyroxad Azoxystrobin Chromafenozide 12 16 20 48.00 WG
Fluxapyroxad Azoxystrobin Tebufenozide 12 16 20 48.00 WG
Fluxapyroxad Trifloxystrobin Fluxametamide 10 16 8 34.00 WG
Fluxapyroxad Trifloxystrobin Isocycloseram 10 16 12 38.00 WG
Fluxapyroxad Trifloxystrobin Broflanilide 16.67 26.67 8 51.34 WG
Fluxapyroxad Trifloxystrobin Chlorantraniliprole 10 16 8 34.00 WG
Fluxapyroxad Trifloxystrobin Cyantraniliprole 16 32 24 72.00 WG
Fluxapyroxad Trifloxystrobin Cyclaniliprole 8 16 8 32.00 WG
Fluxapyroxad Trifloxystrobin Tetraniliprole 5.33 10.66 5.33 21.32 SC
Fluxapyroxad Trifloxystrobin Chlorantraniliprole 10 20 10 40.00 WG
Fluxapyroxad Trifloxystrobin Methoxyfenozide 3.2 6.4 16 25.60 SC
Fluxapyroxad Trifloxystrobin Emamectin benzoate 4 8 1.2 13.20 SC
Fluxapyroxad Trifloxystrobin Indoxacarb 10 20 15 45.00 WG
Fluxapyroxad Trifloxystrobin Novaluron 4 8 7.5 19.50 SE
Fluxapyroxad Trifloxystrobin Chromafenozide 12 16 20 48.00 WG
Fluxapyroxad Trifloxystrobin Tebufenozide 12 16 20 48.00 WG
Fluxapyroxad Picoxystrobin Tolfenpyrad 5 6.25 15 26.25 WG
Fluxapyroxad Picoxystrobin Fluxametamide 5 6.25 4 15.25 SE
Fluxapyroxad Picoxystrobin Isocycloseram 5 6.25 6.25 17.50 SC
Fluxapyroxad Picoxystrobin Broflanilide 5 12.5 5 22.50 SC
Fluxapyroxad Picoxystrobin Chlorantraniliprole 8 16 8 32.00 WG
Fluxapyroxad Picoxystrobin Cyantraniliprole 8 16 12 36.00 WG
Fluxapyroxad Picoxystrobin Cyclaniliprole 4 8 4 16.00 SE
Fluxapyroxad Picoxystrobin Tetraniliprole 5.33 10.66 5.33 21.32 SC
Fluxapyroxad Picoxystrobin Methoxyfenozide 7.5 7.5 16 31.00 SC
Fluxapyroxad Picoxystrobin Emamectin benzoate 7.5 7.5 1.2 16.20 SC
Fluxapyroxad Picoxystrobin Indoxacarb 7.5 7.5 7.5 22.50 SC
Fluxapyroxad Picoxystrobin Novaluron 7.5 7.5 7.5 22.50 SE
Fluxapyroxad Picoxystrobin Chromafenozide 6 10 10 26.00 WG
Fluxapyroxad Picoxystrobin Tebufenozide 6 10 10 26.00 WG
Fluxapyroxad Kresoxim methyl Fluxametamide 5 6.25 4 15.25 SE
Fluxapyroxad Kresoxim methyl Isocycloseram 5 6.25 6.25 17.50 SC
Fluxapyroxad Kresoxim methyl Broflanilide 5 12.5 5 22.50 SC
Fluxapyroxad Kresoxim methyl Chlorantraniliprole 8 16 8 32.00 WG
Fluxapyroxad Kresoxim methyl Cyantraniliprole 8 16 12 36.00 WG
Fluxapyroxad Kresoxim methyl Cyclaniliprole 4 8 4 16.00 SE
Fluxapyroxad Kresoxim methyl Tetraniliprole 5.33 10.66 5.33 21.32 SC
Fluxapyroxad Kresoxim methyl Methoxyfenozide 3.2 6.4 16 25.60 SC
Fluxapyroxad Kresoxim methyl Emamectin benzoate 4 8 1.2 13.20 SC
Fluxapyroxad Kresoxim methyl Indoxacarb 4 8 7.5 19.50 SC
Fluxapyroxad Kresoxim methyl Novaluron 4 8 7.5 19.50 SE
Fluxapyroxad Kresoxim methyl Chromafenozide 12 16 28.00 WG
Fluxapyroxad Kresoxim methyl Tebufenozide 12 16 28.00 WG

Biological Examples:
The synergistic pesticide action of the inventive mixtures can be demonstrated by the experiments below. A synergistic effect exists wherever the action of a combination (ready-mix) or tank mix of active ingredient is greater than the sum of the action of each of the components alone. Therefore, a synergistically effective amount or an effective amount of a synergistic composition or combination is an amount that exhibits greater pesticide activity than the sum of the pesticide activities of the individual components.

In the field of agriculture, it is often understood that the term “synergy” is as defined by Colby S.R. in an article entitled “Calculation of the synergistic and antagonistic responses of herbicide combinations” published in the journal Weeds, 1967, 15, p.20-22, incorporated herein by reference in its entirety. The action expected for a given combination of two or three active components can be calculated as follows:

The objective of the present studies was to study the synergism and benefits. The various compositions comprising Fluxapyroxad, at least one strobilurin fungicide compound A and one more insecticide were evaluated on various crops.

Example 1: Synergistic action of Fluxapyroxad + strobilurin fungicide+ tolfenpyrad.
Crop : Chilli
Location : Umreth, Gujarat
Number of Treatments: 22
Plot size : 6 m x 5 m
Crop stage : 75 days after transplanting.
Method of application: foliar spray with battery operated backpack sprayer
Water volume : 430 liter per hectare
Observation Methods:
Powdery mildew (caused by Leveillula Taurica):
The severity of powdery mildew was scored at 10 days after spray. The disease severity of powdery mildew was recorded on 10 plants and 10 leaves on lower, middle and upper leaves by using 0-9 disease rating scale and expressed as Percent Disease Index (PDI).

Powdery mildew of chilli disease rating scale:
Score Description
0 No symptoms of powdery mildew
1 Small scattered powdery mildew specks covering 1% or less leaf area
3 Small powdery lesions covering 1-10% of leaf area
5 Powdery lesions enlarged covering 11-25% of leaf area
7 Powdery lesions coalesce to form big patches covering 26-50% of leaf area
9 Big powdery patches covering 51% or more of leaf area and defoliation

Thrips (Scirtothrips dorsalis): Count the number of live thrips by shaking the twigs on black piece of paper. Record the observations from 3 twigs per plant and 10 plants per plot on 7th DAA (days after application). Calculate thrips control (%) as observed control and apply Colby’s formula to calculate synergism.

Fruit count: Count the number of healthy fruits per plant. Record the observations from 10 plants per plot and calculate increase (%) in healthy fruits over UTC (untreated check).
Crop vigor: Crop vigor recorded by visual observation considering rapid growth, plant canopy, leaf and fruit color, number of branches, flowers, fruits, leaves. Crop vigour rating given from 1 to 10 scale, 1 means normal poor growth with stunted plants with less number of leaves, flowers, fruits, branches, whereas 10 means excellent vigor with very large plant canopy, higher number of leaves, flowers, fruits, branches.

Table 1: Treatment details
Treatment Number Treatment compositions gram actives per hectare
T1 Fluxapyroxad 10%+pyraclostrobin 18%+tolfenpyrad 16% WG 40+72+64
T2 Fluxapyroxad 10%+trifloxystrobin 18%+tolfenpyrad 16% WG 40+72+64
T3 Fluxapyroxad 7.5%+azoxystrobin 7.5%+tolfenpyrad 10% SC 60+60+80
T4 Fluxapyroxad 7.5%+picoxystrobin 7.5%+tolfenpyrad 10% SC 60+60+80
T5 pyraclostrobin 18%+tolfenpyrad 16% WG 72+64
T6 trifloxystrobin 18%+tolfenpyrad 16% WG 72+64
T7 azoxystrobin 7.5%+tolfenpyrad 10% SC 60+80
T8 picoxystrobin 7.5%+tolfenpyrad 10% SC 60+80
T9 Fluxapyroxad 10%+pyraclostrobin 18% WG 40+72
T10 Fluxapyroxad 10%+trifloxystrobin 18% WG 40+72
T11 Fluxapyroxad 7.5%+azoxystrobin 7.5% SC 60+80
T12 Fluxapyroxad 7.5%+picoxystrobin 7.5% SC 60+80
T13 Fluxapyroxad 10%+tolfenpyrad 16% SC 40+64
T14 Fluxapyroxad 7.5%+tolfenpyrad 10% SC 60+80
T15 Fluxapyroxad 33.3% FS 40
T16 Fluxapyroxad 33.3% FS 60
T17 Tolfenpyrad 15% EC 64
T18 Tolfenpyrad 15% EC 80
T19 pyraclostrobin 20% WG 72
T20 trifloxystrobin 50% WG 72
T21 azoxystrobin 25% SC 60
T22 picoxystrobin 20% SC 60
T23 Untreated Check (UTC) -
T1 to T4-present compositions, T5 to T14-binary mixtures, T15 to T22-market products.

Table 2: Synergistic control of powdery mildew and Thrips control in chilli crop

Treatment Number Powdery mildew control (%) Thrips control (%) No. of fruits per plant Crop vigor rating
control observed control expected Colby's ratio control observed control expected Colby's ratio
T1 100.0 91.7 1.09 85.4 79.8 1.07 67.5 8.2
T2 100.0 92.0 1.09 86.8 80.0 1.09 65.8 8.0
T3 100.0 91.9 1.09 92.2 91.6 1.01 66.3 8.2
T4 100.0 91.5 1.09 93.2 91.6 1.02 63.7 7.8
T5 82.6 81.5 1.01 61.4 62.1 0.99 56.3 6.4
T6 83.4 82.2 1.01 62.0 62.3 0.99 55.9 6.2
T7 85.0 84.4 1.01 78.8 79.8 0.99 54.6 5.8
T8 84.0 83.6 1.00 78.2 79.7 0.98 53.3 5.6
T9 84.2 83.0 1.01 48.8 49.4 0.99 49.5 6.4
T10 84.6 83.6 1.01 48.4 49.7 0.97 48.7 6.4
T11 81.0 79.7 1.02 60.4 61.3 0.98 48.5 6.0
T12 80.6 78.7 1.02 60.2 61.0 0.99 46.2 5.4
T13 79.6 78.2 1.02 77.0 78.8 0.98 50.4 5.2
T14 80.8 79.4 1.02 90.2 91.1 0.99 55.7 6.0
T15 55.2 - - 46.8 - - 42.1 4.2
T16 48.2 - - 58.6 - - 44.3 4.6
T17 51.4 - - 60.2 - - 45.7 4.0
T18 60.2 - - 78.4 - - 47.9 4.4
T19 62.0 - - 4.8 - - 42.6 4.6
T20 63.4 - - 5.4 - - 41.9 4.4
T21 60.8 - - 6.6 - - 42.2 4.0
T22 58.8 - - 5.8 - - 40.5 3.8
T23 0.0 - - 0.0 - - 31.7 3.0

All the present compositions (T1 to T4) provide synergistic control of powdery mildew disease and thrips control as compared to all known binary mixtures (T5 to T14) and market products (T15 to T22). All the present compositions (T1 to T4) show strong synergism (higher the colby’s ratio) with higher crop vigor rating.

Example 2: Synergistic action of Fluxapyroxad +strobilurin fungicide+insecticide.
Crop : Cotton
Location : Sirsa, Haryana
Number of Treatments: 13
Plot size : 10 m x 6 m
Crop stage : 80 days after sowing.
Method of application: foliar spray with battery operated backpack sprayer
Water volume : 520 liter per hectare
Observation Methods:
Cotton leaf spot (caused by Cercospora spp.):
The severity of leaf spot was scored at 10 days after spray. The disease severity of cercospora leaf spot was recorded on 10 plants and 10 leaves on lower, middle and upper leaves by using 0-9 disease rating scale and expressed as Percent Disease Index (PDI).
Thrips (Thrips tabaci): Count the number of live thrips per leaf. Record the observations from 3 leaves per plant and 10 plants per plot on 7th (days after application). Calculate the mean number of thrips per leaf and control (%) as observed control. Apply Colby’s formula to calculate expected control and Colby’s ratio.
Fruiting bodies count: Count the number of fruiting bodies (flowers, square and bolls) per plant, 10 plant per plot. Calculate mean number of fruiting bodies per plant on 20 days after application.

Table 3: Treatment details
Treatment Number Treatment compositions gram actives per hectare
T1 Fluxapyroxad 7.5%+pyraclostrobin 10%+fluxametamide 5% WG 60+80+40
T2 Fluxapyroxad 7.5%+pyraclostrobin 10%+isocycloseram 7.5% SC 60+80+60
T3 Fluxapyroxad 12%+pyraclostrobin 16%+broflanilide 5% SC 60+80+25
T4 pyraclostrobin 20% WG+fluxametamide 10% EC 80+40
T5 pyraclostrobin 20% WG+isocycloseram 20% SC 80+60
T6 pyraclostrobin 20% WG+broflanilide 20% SC 80+25
T7 Fluxapyroxad 12%+pyraclostrobin 16% SC 60+80
T8 Fluxapyroxad 33.3% FS 60
T9 pyraclostrobin 20% WG 80
T10 fluxametamide 10% EC 40
T11 isocycloseram 20% SC 60
T12 broflanilide 20% SC 25
T13 Untreated Check (UTC) -
T1 to T3-present compositions.

Table 4: Synergistic control of leaf spot and thrips in cotton crop
Treatment Number Cotton leaf spot disease control (%) Cotton Thrips control (%) fruiting bodies per plant
Observed Expected Colby's ratio Observed Expected Colby's ratio
T1 95.2 89.6 1.06 87.4 80.7 1.08 68.5
T2 94.8 89.8 1.06 85.2 78.3 1.09 65.6
T3 93.4 89.6 1.04 90.8 81.3 1.12 68.4
T4 71.6 72.4 0.99 77.2 78.9 0.98 56.2
T5 71.2 72.8 0.98 75.0 76.3 0.98 53.4
T6 70.8 72.3 0.98 77.8 79.6 0.98 55.9
T7 86.4 88.9 0.97 12.2 14.4 0.84 48.2
T8 62.4 - - 8.4 - - 41.2
T9 70.4 - - 6.6 - - 40.8
T10 6.8 - - 77.4 - - 46.7
T11 8.2 - - 74.6 - - 45.9
T12 6.4 - - 78.2 - - 46.3
T13 0.0 - - 0.0 - - 34.5

All the present compositions (T1, T2 and T3) provide synergistic control of cotton leaf spot, thrips, and also produce higher number of fruiting bodies per plant.

Example 3: Synergistic action of Fluxapyroxad + pyraclostrobin+ insecticide.
Crop : Rice
Location : Dhamtari, Chhattishgarh
Number of Treatments: 20
Plot size : 6 m x 5 m
Crop stage : 32 days after transplanting.
Method of application: foliar spray with battery operated backpack sprayer
Water volume : 400 liter per hectare
Observation Methods:
Sheath blight (caused by Rhizoctonia solani) control (%):
Observations was recorded on disease severity in each treatment before and at 10 days after spray. The observations of severity of sheath blight disease were recorded using 0-9 grade (SES, IRRI 1996). Twenty randomly selected hills were scored as per scale. The percent disease index (PDI) of plants was calculated by the following formula.

Sheath blight disease grading (0-9 scale):
Grade Symptoms
0 No incidence
1 Less than 1% sheath area infected
3 1-5% sheath area infected
5 6-25% sheath area infected
7 26-50% sheath area infected
9 51-100% sheath area infected

Stem borer control:
The infestation by stem borer was observed as dead heart (DH) appeared during vegetative stage. Count the number of healthy tillers and infested tillers (as dead heart) per hill, record the observations from 10 hills per plot. Calculate dead heart incidence and re-calculate dead heart control (as stem borer control).

Productive tiller: Count the number of productive tillers from 1 sq.m. Spot, record observations from 10 spots per plot before harvesting and calculate mean number of productive tillers per 1 sq.m.

Table 5: Treatment details
S. No. Treatments gram actives per hectare
T1 Fluxapyroxad 10%+pyraclostrobin 16%+chlorantraniliprole 8% SC 50+80+40
T2 Fluxapyroxad 10%+pyraclostrobin 16%+cyantraniliprole 12% WG 50+80+60
T3 Fluxapyroxad 5%+pyraclostrobin 8%+cyclaniliprole 4% SE 50+80+40
T4 Fluxapyroxad 6.67%+pyraclostrobin 10.66%+tetraniliprole 5.33% WG 50+80+40
T5 pyraclostrobin 16%+chlorantraniliprole 8% SC 80+40
T6 pyraclostrobin 16%+cyantraniliprole 12% WG 80+60
T7 pyraclostrobin 8%+cyclaniliprole 4% SE 80+40
T8 pyraclostrobin 10.66%+tetraniliprole 5.33% WG 80+40
T9 Fluxapyroxad 20%+chlorantraniliprole 16% WG 50+40
T10 Fluxapyroxad 20%+cyantraniliprole 24% WG 50+60
T11 Fluxapyroxad 5%+cyclaniliprole 4% SE 50+40
T12 Fluxapyroxad 6.67%+tetraniliprole 5.33% SC 50+40
T13 Fluxapyroxad 10%+pyraclostrobin 16% SC 50+80
T14 Fluxapyroxad 33.33% FS 50
T15 pyraclostrobin 10% CS 80
T16 chlorantraniliprole 20% SC 40
T17 cyantraniliprole 20% SC 60
T18 cyclaniliprole 5% DC 40
T19 tetraniliprole 20% SC 40
T20 Untreated Check (UTC) -

T1 to T4-present compositions

Table 6: Synergistic control of sheath blight disease and stem borer in rice crop
Sr. No. Sheath blight control (%) Stem borer control (%) No. of healthy panicles per sq.m.
Observed Expected Colby's ratio Observed Expected Colby's ratio
T1 98.8 94.8 1.04 90.2 83.6 1.08 307.3
T2 97.2 94.7 1.03 88.4 80.2 1.10 300.8
T3 97.4 94.7 1.03 85.6 78.2 1.10 296.8
T4 96.2 94.6 1.02 86.2 79.7 1.08 301.9
T5 71.2 70.4 1.01 81.4 83.0 0.98 288.3
T6 70.6 69.9 1.01 78.6 79.5 0.99 284.7
T7 71.4 70.1 1.02 76.4 77.3 0.99 280.5
T8 70.8 69.6 1.02 77.2 78.9 0.98 285.6
T9 84.2 83.5 1.01 81.4 83.0 0.98 282.1
T10 85.6 83.2 1.03 78.4 79.6 0.99 277.8
T11 84.4 83.4 1.01 75.6 77.4 0.98 273.4
T12 84.2 83.1 1.01 78.0 79.0 0.99 279.4
T13 95.4 94.4 1.01 3.2 6.7 0.48 280.8
T14 82.4 - - 3.6 - - 250.6
T15 68.4 - - 3.2 - - 247.8
T16 6.2 - - 82.4 - - 263.5
T17 4.8 - - 78.8 - - 261.7
T18 5.4 - - 76.6 - - 256.3
T19 3.8 - - 78.2 - - 260.9
T20 0.0 - - 0.0 - - 228.5

All the present compositions (T1, T2, T3 and T4) provides synergistic control of sheath blight disease and stem borer, and also produces higher number of productive tillers as compared to binary mixtures (T5 to T13).

Example 4: Synergistic control of Flower rots disease in marigold.
Crop : Marigold
Location : Umreth, Gujarat
Treatments : 14
Crop age : 63 days after transplanting.
Spray water volume : 400 liter per hectare.
Method of Application: Foliar spray with battery operated knapsack sprayer fitted with hollow cone nozzle.
Observation Methods:
Flower rot (Alternaria spp.) incidence (%): Count the number of diseases flower and healthy flowers per plant. Record the observations from 10 plants per plot.
Table 7: Treatment details
S.No. Treatments gram actives per hectare
T1 Fluxapyroxad 10%+trifloxystrobin 20%+chlorantraniliprole 10% WG 40+80+40
T2 Fluxapyroxad 3.2%+trifloxystrobin 6.4%+methoxyfenozide 16% SC 40+80+200
T3 Fluxapyroxad 4%+trifloxystrobin 8%+emamectin benzoate 1.2% SC 40+80+12
T4 Fluxapyroxad 10%+trifloxystrobin 20%+indoxacarb 15% SC 40+80+60
T5 Fluxapyroxad 4%+trifloxystrobin 8%+novaluron 7.5% SE 40+80+75
T6 Fluxapyroxad 10%+trifloxystrobin 20% WG 40+80
T7 Fluxapyroxad 33.33% FS 40
T8 trifloxystrobin 25% WG 80
T9 chlorantraniliprole 20% SC 40
T10 methoxyfenozide 24% SC 200
T11 emamectin benzoate 5% SG 12
T12 indoxacarb 15% EC 60
T13 novaluron 10% EC 75
T14 Untreated Check (UTC) -

T1 to T5-present compositions

Table 8: Control of flower rot diseases
S.No. Flower rot disease control (%) Number of flowers per plant Increase (%) in flowers over T24
Observed Expected Colby's ratio
T1 96.4 92.7 1.04 36.5 134.0
T2 95.4 92.6 1.03 33.8 116.7
T3 93.8 92.5 1.01 35.3 126.3
T4 94.4 92.4 1.02 36.1 131.4
T5 96.2 92.5 1.04 32.7 109.6
T6 93.8 92.2 1.02 27.5 76.3
T7 75.2 - - 24.3 55.8
T8 68.4 - - 23.9 53.2
T9 6.8 - - 20.3 30.1
T10 5.2 - - 19.8 26.9
T11 4.0 - - 20.4 30.8
T12 3.6 - - 20.1 28.8
T13 4.2 - - 19.8 26.9
T14 0 - - 15.6 0.0

All the present compositions (T1 to T5) provide synergistic control of flower rot disease and produces higher number of healthy flowers per plant.
Example 5: Synergistic control of early blight disease in tomato crop.
Crop : Tomato
Location : Rajnandgaon, Chhattisgarh
Treatments : 12
Crop age : 60 days after transplanting.
Spray water volume : 500 liter per hectare
Method of Application: Foliar spray with battery operated knapsack sprayer fitted with hollow cone nozzle.
Observation Methods:
Early blight (caused by Alternaria solani) control:
The disease severity was recorded on 10 plants and 10 leaves on lower, middle and upper leaves by using 0-9 disease rating scale and expressed as Percent Disease Index (PDI).
Crop vigor: Crop vigor recorded by visual observations as per example 1.

Table 9: Treatment details
S.No. Treatments gram actives per hectare
T1 Fluxapyroxad 10%+azoxystrobin 15%+fluxametamide 8% SE 50+75+40
T2 Fluxapyroxad 10%+azoxystrobin 15%+isocycloseram 12% SC 50+75+60
T3 Fluxapyroxad 10%+azoxystrobin 15%+broflanilide 5% SC 50+75+25
T4 Fluxapyroxad 10%+azoxystrobin 15%+chlorantraniliprole 8% SC 50+75+40
T5 Fluxapyroxad 10%+azoxystrobin 15% SC 50+75
T6 Fluxapyroxad 33.33% FS 50
T7 azoxystrobin 25% SC 75
T8 fluxametamide 10% EC 40
T9 isocycloseram 10% DC 60
T10 broflanilide 20% SC 25
T11 chlorantraniliprole 20% SC 40
T12 Untreated Check (UTC) -

T1 to T4-present compositions

Table 10: control of early blight disease
S.No.. Early blight disease control (%) Crop vigor rating Number of healthy fruits per plant Increase (%) in fruits over T12
Observed Expected Colby's ratio
T1 96.2 87.2 1.10 8.3 47.3 78.5
T2 95.8 87.3 1.10 8.1 45.6 72.1
T3 97.2 87.0 1.12 8.4 48.2 81.9
T4 96.4 86.9 1.11 8.2 44.9 69.4
T5 87.8 86.2 1.02 7.8 36.8 38.9
T6 68.4 4.3 33.5 26.4
T7 56.2 4.1 32.8 23.8
T8 7.2 4.6 37.8 42.6
T9 8.4 4.2 35.6 34.3
T10 6.2 4.7 40.2 51.7
T11 5.0 4.5 37.3 40.8
T12 0 3.3 26.5 0.0

All the present compositions (T1 to T4) provides synergistic control of early blight disease, shows higher crop vigor and produces more number of healthy fruits per plant.

The innovative compositions of Fluxapyroxad +strobilurin fungicide+insecticide show synergism in terms of insect-pests and diseases control and also produces more fruits, flowers and grains, increases spectrum of control, reduces number of pesticidal applications under field conditions.
,CLAIMS:I/We Claims:

1. A fungicidal composition comprises:
a. fungicide Compound A is Fluxapyroxad or its agrochemically acceptable salts esters and derivatives;
b. another fungicide Compound B strobilurin is selected from Azoxystrobin, Picoxystrobin, Pyraclostrobin, Trifloxystrobin, Metominostrobin or Kresoxim methyl;
c. insecticide Compound C is selected from Tolfenpyrad, Fluxametamide, Isocycloseram, Broflanilide, Chlorantraniliprole, Cyantraniliprole, Cyclaniliprole, Tetraniliprole, Pioxaniliprole, Methoxyfenozide, Chromafenozide, Tebufenozide, Emamectin benzoate, Indoxacarb or Novaluron; and
d. one or more inactive excipients.

2. The fungicidal composition as claimed in claim 1, wherein a fungicide compound A is present in the range of 4% to 30%w/w; b) fungicide compound B is present in the range of 4% to 30%w/w; and c) insecticide compound C is present in the range of 1% to 30%w/w.

3. The fungicidal composition claimed in claim 1, wherein one or more inactive excipients is selected from wetting agents, wetting-spreading-penetrating agent, dispersant or dispersing agent, anti-freezing agent, emulsifying agent, anti-foam agent, preservatives, solvents, co-solvents, preservative, stabilizer, diluent, carriers, suspension aid or suspending agent, thickener, and buffering agent.

4. The fungicidal composition claimed in claim 1, wherein formulations selected from Wettable granule/Water dispersible granule (WG/WDG), Suspension concentrate (SC) or Suspo-emulsion (SE).

5. The fungicidal composition claimed in claim 4, wherein the Wettable granule (WG) formulation comprises:
a. fungicide compound A present in an amount of 4% to 30%w/w;
b. fungicide compound B present in an amount of 4% to 30%w/w;
c. insecticide compound C present in amount of 1% to 30%w/w;
d. dispersing agent is present in the amount of 1% to 20 % w/w;
e. wetting agent is present in the amount of 1% to 10% w/w;
f. anti-foaming agent is present in the amount 0.5% to 2% w/w.

6. The fungicidal composition in claim 5, wherein dispersing agent is selected from alkylnaphthalene sulfonate sodium salt, sodium polycarboxylate, naphthalene sulfonic acid, sodium salt condensates with formaldehyde, polyalcoxylated alkylphenol, naphthalene sulfonic acid formaldehyde condensate, methyl naphthalene-formaldehyde-condensate sodium salt, naphthalene condensates, lignosulfonates, polyacrylates and phosphate esters, calcium lignosulfonate, lignin sulfonate sodium salt. EO/PO based copolymer, phenol sulfonate, sodium methyl oleoyl taurate, styrene acrylic acid copolymer, propylene oxide-ethylene oxide-copolymer, polyethylene glycol 2, 4, 6-tristyrylphenyl ether, tristyrylphenol-polyglycol ether-phosphate, tristyrylphenole with 16 moles EO, oleyl-polyglycol ether with ethylene oxide, tallow fatty amine polyethylene oxide, nonylphenol, polyglycol ether with 9-10 moles ethylene oxide or mixture thereof.

7. The fungicidal composition in claim 5, wherein wetting agent is selected from sodium N-methyl-N-oleoyl taurate, alkylated naphthalene sulfonate, sodium salt, mixture of isomers of dibutyl naphthalene sulphonic acid sodium salt, sodium di-isopropyl naphthalene sulphonate, sodium Lauryl sulfate, dioctyl sulfate, alkyl naphthalene sulfonates, phosphate esters, sulphosuccinates and non-ionic such as tridecyl alcohol ethoxylate, alkyl or alkaryl sulfonates such as alkylbenzene sulfonates, alpha olefin sulfonate and alkyl naphthalene sulfonates, ethoxylated or non-ethoxylated alkyl or alkaryl carboxylates, alkyl or alkaryl phosphate esters, alkyl polysaccharide, di or mono alkyl sulfosuccinate derivatives, alpha olefin sulfonates, alkyl naphthalene sulfonates, dialkyl sulphosuccinates, butyl, dibutyl, isopropyl and di-isopropyl naphthalene sulfonate salts, C12 alkyl benzene sulfonate or C10-C16 alkyl benzene sulfonate, organosilicons surfactants includes trisiloxane ethoxylate, polydimethylsiloxane, polyoxyethylene methyl polysiloxane, polyoxyalkylene methyl polysiloxane, polyether polymethyl siloxane copolymer, trisiloxane heptamethyl, Polyalkyleneoxide modified heptamethyl trisiloxane, polyether modified polysiloxane, may or may not be in modified form, may be liquid or powder form or mixture thereof.

8. The fungicidal composition claimed in claim 5, wherein antifoaming agent is selected from silicone antifoam emulsion, dimethyl siloxane, polydimethyl siloxane, and vegetable oil based antifoam, tallow based fatty acids or a mixture thereof.

9. The fungicidal composition claimed in claim 4, wherein the Suspension concentrate(SC) formulation comprises:
a. fungicide compound A present in an amount of 4% to 30% w/w;
b. fungicide compound B present in an amount of 4% to 30%w/w;
c. insecticide compound C present in amount of 1% to 30%w/w;
d. super wetting- spreading-penetrating agent present in an amount of 1% to 10% w/w;
e. dispersing agent present in an amount of 1% to 10% w/w;
f. suspending agent present in an amount of 0.25 to 2% w/w;
g. antifoaming agent present in an amount of 0.1% to 2% w/w;
h. anti-freezing agent present in amount of 0.1% to 1% w/w;

10. The fungicidal composition claimed in claim 9, wherein the Super wetting-spreading-pentrating agent is selected from trisiloxane ethoxylate, heptamethyl trisiloxane, modified form includes polyalkyleneoxide modified heptamethyl trisiloxane, polyether modified polysiloxane, polyalkyleneoxide modified trisiloxane, polyalkyleneoxide modified polydimethylsiloxane, may be liquid or powder form or a mixture thereof.

11. The fungicidal composition in claim 9, wherein dispersing agent is selected from Naphthalenesulfonic acid, sodium salt condensate with formaldehyde, alkylated naphthalene sulfonate, sodium salt, sodium salt of naphthalene sulfonate condensate, sodium ligno sulfonate, and sodium polycarboxylate. EO/PO based copolymer, phenol sulfonate, sodium methyl oleoyl taurate, styrene acrylic acid copolymer, propylene oxide-ethylene oxide-copolymer, polyethylene glycol 2,4,6-tristyrylphenyl ether, tristyrylphenol-polyglycol ether-phosphate, tristyrylphenole with 16 moles EO, tristyrylphenol-polyglycol ether-phosphate, oleyl-polyglycol ether with ethylene oxide, tallow fatty amine polyethylene oxide, nonylphenol polyglycol ether with 9-10 moles ethylene oxide or a mixture thereof.

12. The fungicidal composition claimed in claim 9, wherein suspending agent is selected from aluminum magnesium silicate, bentonite clay, silica, attapulgite clay or a mixture thereof.

13. The fungicidal composition claimed in claim 9, wherein antifoaming agent is selected from silicone antifoam emulsion, dimethyl siloxane, polydimethyl siloxane, and vegetable oil based antifoam, tallow based fatty acids or a mixture thereof.

14. The fungicidal composition claimed in claim 9, wherein anti-freezing agent selected from siloxane polyalkylene oxide, polydimethyl siloxane, polysiloxane emulsion, vegetable oil-based antifoam, magnesium stearate or a mixture thereof.

15. The fungicidal composition claimed in claim 4, wherein the Suspension Emulsion (SE) formulation comprises:
a. fungicide compound A present in an amount of 4% to 30% w/w;
b. fungicide compound B present in an amount of 4% to 30%w/w;
c. insecticide compound C present in amount of 1% to 30%w/w;
d. emulsifier present in an amount of 1 to 10 % w/w;
e. solvent is present in a sufficient amount;
f. dispersing agent is present in an amount of 1% to 20% w/w;
g. suspending agent is present in the amount of 0.25% to 2% w/w;

16. The fungicidal composition in claim 15, wherein Emulsifier is selected from dodecylbenzene sulphonate, e.g. Ca-salts or amine salts, and sulphonates of other C11-C16 alkylbenzenes, alkylether sulphates, alkylphenoletherphosphates and ester phosphates; non-ionic surfactants such as alkoxylated alcohols and alkylphenols, ethoxylated fatty acids, ethoxylated vegetable oils, e.g. ethoxylated castor oil, fatty acid esters, e.g. of sorbitol, and their ethoxylated derivatives, ethoxylated amines, and condensates of glycerol; and catanionic emulsifiers such as a cationic amine, optionally in combination with an alkylsulphonate or ether sulphonate or ether phosphate, alkoxylated alcohols; alkoxylated alkylphenols; ethoxylated fatty acids; ethoxylated vegetable oils; ethoxylated tristyrylphenol (tristyrlphenol with 16 moles EO), tristyrylphenol-polyglycolether-phosphate, fatty acid esters of sorbitol and ethoxylated derivatives thereof; ethoxylated amines and condensates of glycerol; sulfonated alkylbenzenes in the range C11-C16 and salts thereof; alkylether sulphates; alkyletherphosphates; alkylphenoletherphosphates; or combinations thereof; salts of phosphate esters of ethoxylated tristyrylphenol; salts of sulphated ethers of ethoxylated tristyrylphenol; or a catanionic system, wherein a cationic amine is present in combination with an alkylsulphonate, an alkylethersulphonate, an ether sulphate, or an ether phosphate such as an alkyletherphosphate, nonylphenol polyethoxy ethanols, castor oil polyglycol ethers, polyadducts of ethylene oxide and polypropylene, tributyl phenoxy polyethoxy ethanol, octyl phenoxy polyethoxy ethanol or a mixture thereof.

17. The fungicidal composition in claim 15, wherein Solvent is selected from n-pentane, hexane(s), cyclohexane, methylcyclohexane, heptane, isooctane, benzene, toluene, xylene(s), isophorone and ester solvents such as methyloleate, dimethylamide and morpholineamide derivatives of C6-C16 fatty acids, and mono-alkylene carbonates such as ethylene carbonate, propylene carbonate and butylene carbonates, dimethylsulfoxide (DMSO), 2-ethylhexanol and n-butanol, n-alkylpyrrolidones, fatty acid dimethyl esters, fatty acid esters, dibasic esters, aromatic hydrocarbons and/or aliphatic hydrocarbons, one or more dimethylamides, such as C8-dimethylamide, C10-dimethylamide, C12-dimethylamide, ethylene glycol, propylene glycol, polyalkylene glycols, aromatic hydrocarbons, methylpyrrolidinone (NMP); dimethylformamide (DMF); dimethylisosorbide (DMI); isophorone; acetophenone; 1,3-dimethyl-2-imidazolidonone; lactate esters; dimethyl and diethylcarbonates; alcohols including methanol; ethanol; iso-propanol; n-propanol; n-butanol; iso-butanol; and tert-butanol; Methyl L-lactate, 2-Ethylhexyl L-lactate, Ethyl L-lactate, n-Butyl L-lactate, Octyl phenol ethoxylates, water, water soluble alcohols and dihydroxy alcohol ethers. Water soluble alcohol or lower alcohol (1-4 carbon atoms) includes-methanol, ethanol, n-propanol, isopropanol, n-butanol, tert-butanol or a mixture thereof.

18. The fungicidal composition in claim 15, wherein Dispersing agent is selected from polyesters, polyamides, poly- carbonates, polyurea and polyurethanes, acrylic polymers, acrylic graft copolymer, styrene copolymers, butadiene copolymers, polysaccharides such as starch and cellulose derivatives, vinylalcohol, vinylacetate and vinylpyrrolidone polymers and copolymers, polyethers, epoxy, phenolic and melamine resins, polyolefins and define copolymers and mixtures thereof. Examples of preferred polymers are acrylate polymers such as poly(methacrylate), poly(ethyl methacrylate), poly(methylmethacrylate), acrylate copoylmers and styrene-acrylic copolymers as defined herein below, poly(styrene-co maleic anhydride), cellulosic polymers such as ethyl cellulose, cellulose acetate, cellulose acetatebutyrate, acetylated mono, di, and triglycerides, poly(vinylpyrrolidone), vinyl acetate polymers and copolymers, poly(alkylene glycol), styrene butadiene copolymers, poly(orthoesters), alkyd resins, biodegradable polyesters, starch, polylactic acid starch blends, polylactic acid, poly(lactic acid-glycolic acid) copolymers, polydioxanone, cellulose esters, ethyl cellulose, cellulose acetate butyrate, starch esters, starch esteraliphatic polyester blends, modified corn starch, polycaprolactone, poly(namylmethacrylate), wood rosin, polyanhydrides, polyvinylalcohol, polyhydroxybutyratevalerate, biodegradable aliphatic polyesters, and polyhydroxybutyrate or mixtures thereof. The examples of dispersing agents are alkylated naphthalene sulfonate, sodium salt, sodium salt of naphthalene sulfonate condensate, sodium salt of alkyl naphthalene sulfonate, sodium ligno sulfonate, sodium ploycarboxylate, EO/PO block copolymer, phenol sulfonate, sodium methyl oleoyl taurate, styrene acrylic acid copolymer, propyleneoxide-ethyleneoxide-copolymer, polyethylene glycol 2,4,6-tristyrylphenyl ether, tristyrylphenol-polyglycolether-phosphate, tristyrylphenole with 16 moles EO, tristyrylphenol-polyglycolether-phosphate, oleyl-polyglycolether with ethylene oxide, tallow fattyamine polyethylene oxide, nonylphenol polyglycolether with 9-10 moles ethylene oxide or there mixture thereof .

19. The fungicidal composition in claim 15, wherein Suspending agent for is selected from aluminum magnesium silicate, bentonite clay, silica, attapulgite clay or a mixture thereof.

Dated this 21st of September 2024.