Abstract: The present invention provides a versatile recombinant expression platform for expression of multi-antigen VLPs and VLP-RNA complexes particularly, VLP-mRNA complexes. The present invention provides a VLP-mRNA complex encapsulating mRNA inside VLP with increased thermostability and protection from ribonucleases, hence, have a shelf life up to 2 years, increased template copy number with enhanced therapeutic outcome. The multivalent VLPs and complexes of the present invention have great potential applications against one or more respiratory, bacteriological and oncological diseases.
DESC:PLEASE SEE ATTACHED ,CLAIMS:PLEASE SEE ATTACHED
| # | Name | Date |
|---|---|---|
| 1 | 202411003811-STATEMENT OF UNDERTAKING (FORM 3) [19-01-2024(online)].pdf | 2024-01-19 |
| 2 | 202411003811-PROVISIONAL SPECIFICATION [19-01-2024(online)].pdf | 2024-01-19 |
| 3 | 202411003811-POWER OF AUTHORITY [19-01-2024(online)].pdf | 2024-01-19 |
| 4 | 202411003811-FORM 1 [19-01-2024(online)].pdf | 2024-01-19 |
| 5 | 202411003811-DRAWINGS [19-01-2024(online)].pdf | 2024-01-19 |
| 6 | 202411003811-DECLARATION OF INVENTORSHIP (FORM 5) [19-01-2024(online)].pdf | 2024-01-19 |
| 7 | 202411003811-Proof of Right [01-07-2024(online)].pdf | 2024-07-01 |
| 9 | 202411003811-Sequence Listing in PDF [19-01-2025(online)].pdf | 2025-01-19 |
| 10 | 202411003811-DRAWING [19-01-2025(online)].pdf | 2025-01-19 |
| 11 | 202411003811-CORRESPONDENCE-OTHERS [19-01-2025(online)].pdf | 2025-01-19 |
| 12 | 202411003811-COMPLETE SPECIFICATION [19-01-2025(online)].pdf | 2025-01-19 |
| 13 | 202411003811-Power of Attorney [21-01-2025(online)].pdf | 2025-01-21 |
| 14 | 202411003811-Form 1 (Submitted on date of filing) [21-01-2025(online)].pdf | 2025-01-21 |
| 15 | 202411003811-Covering Letter [21-01-2025(online)].pdf | 2025-01-21 |