TECHNICAL FIELD
[001] The present invention relates to a homogeneous cobalt
catalyst, TJ3-fluorenyl-(p2-hydoxy) cobalt(II) dimer or [Co(p2-0H)-(TJ3-
Fluorenyl)]2 for room temperature C-H alkylation of aryl ketones
5 with alkyl halides reactions. The catalyst is industrially scalable,
easy to use and cost effective.
[002] Organometallic catalysis is a type of catalysis where chemical
reactions are· sped up by using organometallic molecules.
Organometallic catalysts are made entirely of metals connected to
10 carbon and other elements that are frequently found in
organometallic compounds, in contrast to conventional metal-based
catalysts. These catalysts may catalyze a variety of transformations
in organic synthesis like C-C, C-N, C-0, C-S bond formation
reactions etc organometallic catalysis is a popular strategy in
15 contemporary synthetic chemistry because it has a number of
benefits, such as low reaction conditions, high selectivity, and
environmental friendliness.
[003] Catalysts accelerate chemical reactions by providing an
altemative reaction pathway with lower activation energy, allowing
20 reactions to proceed more rapidly than they would without the
catalyst. They may promote specific pathways or products in a
reaction, enhancing selectivity and reducing the formation of
unwanted by-products. By lowering the activation energy required
for a reaction, catalysts enable reactions to occur at lower
25 temperatures and pressures, leading to energy savings and milder
reaction conditions. They enable atom economy and achieve an
excellent yield of products, thereby improving the overall efficiency
of the reaction process. Many catalysts are compatible with green
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chemistry principles, such as the use of renewable resources, nontoxic
reagents, and solvent-free conditions, contributing to more
sustainable chemical processes. Some catalysts may be recovered
and reused multiple times without losing their activity, reducing
5 costs