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Processes For The Preparation Of Selective Estrogen Receptor Degraders

Abstract: Disclosed are methods of making selective estrogen receptor degraders (SERDs) of Formula (A), as well as intermediates thereof, salts thereof including a pharmaceutically acceptable salt, and pharmaceutical compositions thereof: wherein either R1 or R2 is independently Cl, F, -CF3, or -CH3, and the other is H; and R7 is H or PG.

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Notices, Deadlines & Correspondence

Patent Information

Application #
Filing Date
26 July 2024
Publication Number
51/2024
Publication Type
INA
Invention Field
CHEMICAL
Status
Email
Parent Application

Applicants

ELI LILLY AND COMPANY
Lilly Corporate Center Indianapolis, Indiana 46285

Inventors

1. ARGUELLES DELGADO, Alonso Jose
c/o ELI LILLY AND COMPANY P.O. Box 6288 Indianapolis, Indiana 46206-6288
2. CZESKIS, Boris Arnoldovich
c/o ELI LILLY AND COMPANY P.O. Box 6288 Indianapolis, Indiana 46206-6288
3. HAWK, Mai Khanh Nguyen
c/o ELI LILLY AND COMPANY P.O. Box 6288 Indianapolis, Indiana 46206-6288
4. KJELL, Douglas Patton
c/o ELI LILLY AND COMPANY P.O. Box 6288 Indianapolis, Indiana 46206-6288
5. LU, Yu
c/o ELI LILLY AND COMPANY P.O. Box 6288 Indianapolis, Indiana 46206-6288
6. MAGNUS, Nicholas Andrew
c/o ELI LILLY AND COMPANY P.O. Box 6288 Indianapolis, Indiana 46206-6288
7. REMICK, David Michael
c/o ELI LILLY AND COMPANY P.O. Box 6288 Indianapolis, Indiana 46206-6288

Specification

Documents

Application Documents

# Name Date
1 202417056959-STATEMENT OF UNDERTAKING (FORM 3) [26-07-2024(online)].pdf 2024-07-26
2 202417056959-REQUEST FOR EXAMINATION (FORM-18) [26-07-2024(online)].pdf 2024-07-26
3 202417056959-PROOF OF RIGHT [26-07-2024(online)].pdf 2024-07-26
4 202417056959-POWER OF AUTHORITY [26-07-2024(online)].pdf 2024-07-26
5 202417056959-FORM 18 [26-07-2024(online)].pdf 2024-07-26
6 202417056959-FORM 1 [26-07-2024(online)].pdf 2024-07-26
7 202417056959-DRAWINGS [26-07-2024(online)].pdf 2024-07-26
8 202417056959-DECLARATION OF INVENTORSHIP (FORM 5) [26-07-2024(online)].pdf 2024-07-26
9 202417056959-COMPLETE SPECIFICATION [26-07-2024(online)].pdf 2024-07-26
10 202417056959-Proof of Right [05-08-2024(online)].pdf 2024-08-05
11 202417056959-FORM 3 [14-01-2025(online)].pdf 2025-01-14
12 202417056959-FORM 3 [14-01-2025(online)]-1.pdf 2025-01-14