Solid Phase Peptide Synthesis Wash Process

Abstract: A method is disclosed for washing an amino acid that has been added to a solid phase resin during solid phase peptide synthesis (SPPS), comprising: adding a first quantity of wash solvent, wherein once the wash with the first quantity of wash solvent is complete, sending the first quantity of wash solvent to waste; and adding a second quantity of wash solvent, wherein once the wash with the second quantity of wash solvent is complete, sending the second quantity of wash solvent to a container, wherein the second quantity of wash solvent will be used in the first wash for the next amino acid that is added.

Patent Information

Application #

Filing Date

14 August 2024

Publication Number

51/2024

Publication Type

INA

Invention Field

BIO-CHEMISTRY

Status

Email

Parent Application

Applicants

ELI LILLY AND COMPANY

Lilly Corporate Center Indianapolis, Indiana 46285

Inventors

1. BERGLUND, Mark Richard

c/o ELI LILLY AND COMPANY P.O. Box 6288 Indianapolis, Indiana 46206-6288

Specification

Documents

Application Documents

#	Name	Date
1	202417061782-STATEMENT OF UNDERTAKING (FORM 3) [14-08-2024(online)].pdf	2024-08-14
2	202417061782-REQUEST FOR EXAMINATION (FORM-18) [14-08-2024(online)].pdf	2024-08-14
3	202417061782-PRIORITY DOCUMENTS [14-08-2024(online)].pdf	2024-08-14
4	202417061782-POWER OF AUTHORITY [14-08-2024(online)].pdf	2024-08-14
5	202417061782-FORM 18 [14-08-2024(online)].pdf	2024-08-14
6	202417061782-FORM 1 [14-08-2024(online)].pdf	2024-08-14
7	202417061782-DRAWINGS [14-08-2024(online)].pdf	2024-08-14
8	202417061782-DECLARATION OF INVENTORSHIP (FORM 5) [14-08-2024(online)].pdf	2024-08-14
9	202417061782-COMPLETE SPECIFICATION [14-08-2024(online)].pdf	2024-08-14
10	202417061782-Proof of Right [28-11-2024(online)].pdf	2024-11-28
11	202417061782-FORM 3 [03-02-2025(online)].pdf	2025-02-03