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Sarm1 Rna Interference Agents
Abstract: Provided herein are SARM1 RNAi agents and compositions comprising a SARM1 RNAi agent. Also provided herein are methods of using the SARM1 RNAi agents or compositions comprising a SARM1 RNAi agent for reducing SARM1 expression, reducing axon degeneration, and/or treating SARM1-mediated neurological disease in a subject.
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Notices, Deadlines & Correspondence
Notices, Deadlines & Correspondence
Patent Information
Application #
Filing Date
20 September 2024
Publication Number
2/2025
Publication Type
INA
Invention Field
BIO-CHEMISTRY
Status
Email
Parent Application
Applicants
ELI LILLY AND COMPANY
Lilly Corporate Center
Indianapolis, Indiana 46285
Inventors
1. BABB, Nicholas Alan
c/o ELI LILLY AND COMPANY
P.O. Box 6288
Indianapolis, Indiana 46206-6288
2. HERNANDEZ BUQUER, Selene
c/o ELI LILLY AND COMPANY
P.O. Box 6288
Indianapolis, Indiana 46206-6288
3. LACKNER, Gregory Lawrence
c/o ELI LILLY AND COMPANY
P.O. Box 6288
Indianapolis, Indiana 46206-6288
4. MILES, Rebecca Ruth
c/o ELI LILLY AND COMPANY
P.O. Box 6288
Indianapolis, Indiana 46206-6288
5. PERKINS, Douglas Raymond
c/o ELI LILLY AND COMPANY
P.O. Box 6288
Indianapolis, Indiana 46206-6288
6. WANG, Jibo
c/o ELI LILLY AND COMPANY
P.O. Box 6288
Indianapolis, Indiana 46206-6288
7. WANG, Yaming
c/o ELI LILLY AND COMPANY
P.O. Box 6288
Indianapolis, Indiana 46206-6288
8. KAESER-WOO, Yea Jin
c/o ELI LILLY AND COMPANY
P.O. Box 6288
Indianapolis, Indiana 46206-6288
Specification
Documents
Application Documents
| # | Name | Date |
|---|---|---|
| 1 | 202417071061-STATEMENT OF UNDERTAKING (FORM 3) [20-09-2024(online)].pdf | 2024-09-20 |
| 3 | 202417071061-Sequence Listing in PDF [20-09-2024(online)].pdf | 2024-09-20 |
| 4 | 202417071061-REQUEST FOR EXAMINATION (FORM-18) [20-09-2024(online)].pdf | 2024-09-20 |
| 5 | 202417071061-POWER OF AUTHORITY [20-09-2024(online)].pdf | 2024-09-20 |
| 6 | 202417071061-FORM-26 [20-09-2024(online)].pdf | 2024-09-20 |
| 7 | 202417071061-FORM 18 [20-09-2024(online)].pdf | 2024-09-20 |
| 8 | 202417071061-FORM 1 [20-09-2024(online)].pdf | 2024-09-20 |
| 9 | 202417071061-DECLARATION OF INVENTORSHIP (FORM 5) [20-09-2024(online)].pdf | 2024-09-20 |
| 10 | 202417071061-COMPLETE SPECIFICATION [20-09-2024(online)].pdf | 2024-09-20 |
| 11 | 202417071061-CLAIMS UNDER RULE 1 (PROVISIO) OF RULE 20 [20-09-2024(online)].pdf | 2024-09-20 |
| 12 | 202417071061-FORM 3 [20-01-2025(online)].pdf | 2025-01-20 |
| 13 | 202417071061-Proof of Right [19-03-2025(online)].pdf | 2025-03-19 |