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At2 R Antagonists And Uses Thereof

Abstract: This invention provides certain piperidine compounds as AT2R antagonists, e.g., compounds of formula (I): or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, and X are as defined herein, pharmaceutical compositions thereof, and methods of using the same to treat pain associated with AT2R activity.

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Patent Information

Application #
Filing Date
05 December 2024
Publication Number
1/2025
Publication Type
INA
Invention Field
CHEMICAL
Status
Email
Parent Application

Applicants

ELI LILLY AND COMPANY
Lilly Corporate Center Indianapolis, Indiana 46285

Inventors

1. BEAUCHAMP, Thomas James
c/o Eli Lilly and Company P.O. Box 6288 Indianapolis, Indiana 46206-6288
2. CHEN, Zhaogen
c/o Eli Lilly and Company P.O. Box 6288 Indianapolis, Indiana 46206-6288
3. CONNER, Scott Eugene
c/o Eli Lilly and Company P.O. Box 6288 Indianapolis, Indiana 46206-6288
4. ERICKSON, Jon Andre
c/o Eli Lilly and Company P.O. Box 6288 Indianapolis, Indiana 46206-6288
5. GARCIA PAREDES, Maria Cristina
c/o Eli Lilly and Company P.O. Box 6288 Indianapolis, Indiana 46206-6288
6. LINESWALA, Jayana Pankajkumar
c/o Eli Lilly and Company P.O. Box 6288 Indianapolis, Indiana 46206-6288
7. SHER, Emanuele
c/o Eli Lilly and Company P.O. Box 6288 Indianapolis, Indiana 46206-6288
8. THAPA, Bishnu
c/o Eli Lilly and Company P.O. Box 6288 Indianapolis, Indiana 46206-6288
9. WINNEROSKI, Leonard Larry II
c/o Eli Lilly and Company P.O. Box 6288 Indianapolis, Indiana 46206-6288

Specification

Documents

Application Documents

# Name Date
1 202417096081-STATEMENT OF UNDERTAKING (FORM 3) [05-12-2024(online)].pdf 2024-12-05
2 202417096081-POWER OF AUTHORITY [05-12-2024(online)].pdf 2024-12-05
3 202417096081-FORM 1 [05-12-2024(online)].pdf 2024-12-05
4 202417096081-FIGURE OF ABSTRACT [05-12-2024(online)].pdf 2024-12-05
5 202417096081-DECLARATION OF INVENTORSHIP (FORM 5) [05-12-2024(online)].pdf 2024-12-05
6 202417096081-COMPLETE SPECIFICATION [05-12-2024(online)].pdf 2024-12-05
7 202417096081-CLAIMS UNDER RULE 1 (PROVISIO) OF RULE 20 [05-12-2024(online)].pdf 2024-12-05
8 202417096081-MARKED COPIES OF AMENDEMENTS [10-12-2024(online)].pdf 2024-12-10
9 202417096081-FORM 18 [10-12-2024(online)].pdf 2024-12-10
10 202417096081-FORM 13 [10-12-2024(online)].pdf 2024-12-10
11 202417096081-AMMENDED DOCUMENTS [10-12-2024(online)].pdf 2024-12-10
12 202417096081-Proof of Right [19-02-2025(online)].pdf 2025-02-19
13 202417096081-FORM 3 [06-03-2025(online)].pdf 2025-03-06