Pharmaceutical Composition For Inhibition Of Dna Polymerase Kappa (Pol

Pharmaceutical Composition For Inhibition Of Dna Polymerase Kappa (Pol K)

Abstract: The present invention relates to a pharmaceutical composition comprising 2-(2- chlorophenyl)-5-[6-phenoxy-4-(trifluoromethyl) pyridin-3-yl]-1,3,4-oxadiazole and MgCl2 as a DNA Polymerase Kappa inhibitor, methods of preparing them, and methods of treatment, prevention, and amelioration of DNA Polymerase Kappa-based diseases or disorders with them. The present invention also relates to a pharmaceutical composition comprising 2-(2-chlorophenyl)-5-[6-phenoxy-4-(trifluoromethyl) pyridin-3-yl]-1,3,4- oxadiazole, MgCl2, and an anti-cancer agent.

Patent Information

Application #

Filing Date

25 January 2024

Publication Number

31/2025

Publication Type

INA

Invention Field

BIO-CHEMISTRY

Status

Email

Parent Application

Applicants

Institute of Life Sciences

Nalco Square, Chandrashekharpur, Bhubaneswar-751023, Odisha, India

Inventors

1. Soumen Chakraborty

Cancer Biology Group, Institute of Life Sciences (an autonomous institute under the Department of Biotechnology, Biotechnology Research Innovation Council, Govt. of India), Nalco Square, Chandrashekharpur, Bhubaneswar-751023, Odisha, India

2. Sumit Biswas

Dept. of Biological Sciences, BITs Pilani, KK Birla Goa Campus, Zuarinagar Goa-403726, India

3. Shristi Lama

Cancer Biology Group, Institute of Life Sciences (an autonomous institute under the Department of Biotechnology, Biotechnology Research Innovation Council, Govt. of India), Nalco Square, Chandrashekharpur,

Specification

DESC:As attached ,CLAIMS:As attached

Documents

Application Documents

#	Name	Date
1	202431005238-STATEMENT OF UNDERTAKING (FORM 3) [25-01-2024(online)].pdf	2024-01-25
2	202431005238-PROVISIONAL SPECIFICATION [25-01-2024(online)].pdf	2024-01-25
3	202431005238-FORM FOR SMALL ENTITY(FORM-28) [25-01-2024(online)].pdf	2024-01-25
4	202431005238-FORM 1 [25-01-2024(online)].pdf	2024-01-25
5	202431005238-EVIDENCE FOR REGISTRATION UNDER SSI(FORM-28) [25-01-2024(online)].pdf	2024-01-25
6	202431005238-EDUCATIONAL INSTITUTION(S) [25-01-2024(online)].pdf	2024-01-25
7	202431005238-DRAWINGS [25-01-2024(online)].pdf	2024-01-25
8	202431005238-DECLARATION OF INVENTORSHIP (FORM 5) [25-01-2024(online)].pdf	2024-01-25
9	202431005238-Proof of Right [10-02-2024(online)].pdf	2024-02-10
10	202431005238-FORM-26 [10-02-2024(online)].pdf	2024-02-10
11	202431005238-DRAWING [17-01-2025(online)].pdf	2025-01-17
12	202431005238-CORRESPONDENCE-OTHERS [17-01-2025(online)].pdf	2025-01-17
13	202431005238-COMPLETE SPECIFICATION [17-01-2025(online)].pdf	2025-01-17
14	202431005238-FORM 18 [15-04-2025(online)].pdf	2025-04-15