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A Novel Process For The Preparation Of (6 R) 6 (2 (N (4 (2 (Ethylamino) Ethyl) Benzyl) N Ethylamino) 4 Methoxyphenyl) 5,6,7,8 Tetrahydronaphthalen 2 Ol Dihydrochloride And It’s Intemediates
Abstract: ?A NOVEL PROCESS FOR THE PREPARATION OF (6R)-6-(2-(N-(4-(2-(ETHYLAMINO) ETHYL) BENZYL)-N-ETHYLAMINO)-4-METHOXYPHENYL)-5,6,7,8-TETRAHYDRONAPHTHALEN-2-OL DIHYDROCHLORIDE AND IT’S INTEMEDIATES ? The present invention relates to a process for the preparation of (6R)-6-(2-(N-(4-(2-(ethylamino)ethyl)benzyl)-N-ethylamino)-4-methoxyphenyl)-5,6,7,8-tetrahydro nap- hthalen-2-ol dihydrochloride (1) and its novel intermediates thereof. Elacestrant dihydrochloride (1) The present invention further relates to a process for the preparation of intermediates of formula (3), formula (4), formula (4a), formula (5), formula (5a), formula (6), formula (6a), formula (7), formula (7a), formula (9) and formula (10). with enantiomeric excess greater than 50%.
Notices, Deadlines & Correspondence
Patent Information
Applicants
BIOPHORE INDIA PHARMACEUTICALS PVT. LTD
Inventors
1. Manik Reddy Pullagurla
2. Bhaskar Reddy Pitta
3. Jagadeesh Babu Rangisetty
Specification
DESC:Enclosed ,CLAIMS:Enclosed
Documents
Application Documents
| # | Name | Date |
|---|---|---|
| 1 | 202441027906-PROVISIONAL SPECIFICATION [04-04-2024(online)].pdf | 2024-04-04 |
| 2 | 202441027906-FORM 1 [04-04-2024(online)].pdf | 2024-04-04 |
| 3 | 202441027906-Proof of Right [09-10-2024(online)].pdf | 2024-10-09 |
| 4 | 202441027906-FORM-5 [04-04-2025(online)].pdf | 2025-04-04 |
| 5 | 202441027906-COMPLETE SPECIFICATION [04-04-2025(online)].pdf | 2025-04-04 |
| 6 | 202441027906-Covering Letter [08-05-2025(online)].pdf | 2025-05-08 |