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A Recombinant Sigma Factor, Recombinant Bacterium, Methods Of Preparation And Applications Thereof

Abstract: ABSTRACT A RECOMBINANT SIGMA FACTOR, RECOMBINANT BACTERIUM, METHODS OF PREPARATION AND APPLICATIONS THEREOF The present disclosure relates to a recombinant sigma factor having at least one exogenous 5 modification. The exogenous modification is present in the form of an exogenous linker between sigma 2 and sigma 4 of the sigma factor and/or L3 loop in the sigma 2 domain of the sigma factor. The disclosure also discloses a recombinant bacteria comprising the recombinant sigma factor. Also provided are uses of the recombinant bacteria in biochemical pathways for producing phytochemicals or flavonoids. The advantage of the present disclosure is that it provides an 10 environment friendly and economical production strategy of phytochemicals.

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Patent Information

Application #
Filing Date
19 April 2024
Publication Number
17/2025
Publication Type
INA
Invention Field
BIOTECHNOLOGY
Status
Email
Parent Application

Applicants

INDIAN INSTITUTE OF SCIENCE
CV Raman Road Bangalore Karnataka India 560012

Inventors

1. SANKAR MAHESH R
Room 301, Molecular Biophysics Unit, Indian Institute of Science, Bangalore 560012, Karnataka, India
2. SAVITHA D NADIG
Room 301, Molecular Biophysics Unit, Indian Institute of Science, Bangalore 560012, Karnataka, India
3. NISHANK REDDY M
Room 301, Molecular Biophysics Unit, Indian Institute of Science, Bangalore 560012, Karnataka, India
4. BALASUBRAMANIAN GOPAL
Room 301, Molecular Biophysics Unit, Indian Institute of Science, Bangalore 560012, Karnataka, India

Specification

DESC:AS FILED PDF DOCUMENT ,CLAIMS:AS FILED PDF DOCUMENT

Documents

Application Documents

# Name Date
1 202441031467-STATEMENT OF UNDERTAKING (FORM 3) [19-04-2024(online)].pdf 2024-04-19
2 202441031467-PROVISIONAL SPECIFICATION [19-04-2024(online)].pdf 2024-04-19
3 202441031467-PROOF OF RIGHT [19-04-2024(online)].pdf 2024-04-19
4 202441031467-POWER OF AUTHORITY [19-04-2024(online)].pdf 2024-04-19
5 202441031467-FORM FOR SMALL ENTITY(FORM-28) [19-04-2024(online)].pdf 2024-04-19
6 202441031467-FORM 1 [19-04-2024(online)].pdf 2024-04-19
7 202441031467-EVIDENCE FOR REGISTRATION UNDER SSI(FORM-28) [19-04-2024(online)].pdf 2024-04-19
8 202441031467-EDUCATIONAL INSTITUTION(S) [19-04-2024(online)].pdf 2024-04-19
9 202441031467-DRAWINGS [19-04-2024(online)].pdf 2024-04-19
10 202441031467-DECLARATION OF INVENTORSHIP (FORM 5) [19-04-2024(online)].pdf 2024-04-19
12 202441031467-Sequence Listing in PDF [17-04-2025(online)].pdf 2025-04-17
13 202441031467-FORM-9 [17-04-2025(online)].pdf 2025-04-17
14 202441031467-FORM-8 [17-04-2025(online)].pdf 2025-04-17
15 202441031467-FORM 18A [17-04-2025(online)].pdf 2025-04-17
16 202441031467-EVIDENCE OF ELIGIBILTY RULE 24C1f [17-04-2025(online)].pdf 2025-04-17
17 202441031467-DRAWING [17-04-2025(online)].pdf 2025-04-17
18 202441031467-CORRESPONDENCE-OTHERS [17-04-2025(online)].pdf 2025-04-17
19 202441031467-COMPLETE SPECIFICATION [17-04-2025(online)].pdf 2025-04-17