DESC:FIELD OF INVENTION
[0001] The present disclosure relates to the field of cosmetics. Specifically, the present disclosure relates to an oxidant system with low quantities of peroxide levels that can provide high levels of lightening of hair, or skin, and hair colouring with or without lightening powder/cream. More specifically the present disclosure relates to an oxidant system composition comprising a phosphate ester of specific log p value in conjunction with low level of peroxide to achieve high levels of lightening of hair, skin, and hair colouring that can afford less damage to hair and skin.

BACKGROUND OF THE INVENTION
[0002] The background description includes information that may help understand the current invention. It is not an admission that any of the data presented in the present application is previous knowledge or pertinent to the invention currently being claimed, nor is it an admission that any publication directly or implicitly referred to in the present application is prior knowledge.
[0003] Oxidizing agents are often used in cosmetic applications such as hair or skin bleaching/lightening, and hair colouring. For example, for lightening of keratin fibres, peroxides are used in the presence of alkalizing agents. This requires harsher conditions to efficiently lighten the natural pigment. Though, there are plenty of oxidative pre-lightening and colorant compositions, they all use high levels of oxidising agents that damages both skin and hair. Thus, there is a need for compositions that can include relatively less amounts of oxidizing agent and those which are stable.
[0004] For skin related cosmetics, tanning due to over-exposure to sunlight is well known and individuals are willing to use products which can de-tan the skin. There is also a high demand for products that can lighten the skin. Skin bleach / de-tan products are available in the market and the most commonly used ones use comparatively higher amounts of oxidising agents / alkalizing agents that can damage skin, as skin may become more red, inflamed and itchy due to the effects of high concentrations / presence of such substances that may have alkaline. Thus, there remains an unmet need for a composition that can contain comparatively lower amount of oxidizing agent and pH which is not alkaline.
[0005] Some of the literature disclosing different approaches towards use of less oxidising agents for lightening of hair, skin, and hair colouring are discussed herein below.
[0006] EP3941424A discloses a hair coloring and/or bleaching compositions; wherein the composition has a pH of less than 9 and the buffering system maintains the pH of the composition between 6 and 8. The pH of the composition is thus maintained at near neutral to alkaline and the composition does not provide pre-lightening/lifting effect on hair. Besides, the main focus is to maintain desired viscosity and does not demonstrate effectiveness in hair bleaching or coloring.
[0007] JP2008521832A discloses an oxidative hair dyeing and oxidative bleaching composition. The pH of the composition is mentioned to be up to and including pH 9.5 and preferable pH is about 9. As per the Examples 1-10, the actual pH of the composition is maintained at 9. Thus, the pH of the composition is alkaline, which is known to damage hair. There is no data provided in to demonstrate the composition to have lifting / hair lightening effect.
[0008] EP1415641B1 discloses an oxidative crème in form of an oil-in water emulsion for treating human keratin fibres. The emulsion comprises 50-65% peroxide and requires refrigeration. Such high amounts of peroxide can be very harsh for hair. Further, the emulsion is mentioned to include amphiphilic polymer for stabilizing the viscosity of an oil-in-water oxidizing emulsion. Thus, the main focus is to maintain the stability of the emulsion but there is no demonstration that the emulsion can have effect on lightening/lifting of hair.
[0009] US8778032B2 discloses a composition for oxidatively changing the color of keratinic fibers in particular human hair. However, it is only for hair coloring and there is no disclosure for the composition to be effective for lightening / bleaching and colouring of hair.
[0010] EP3545945A1 relates to a fluid/creamy pigmented hydrogen peroxide-based oxidizing composition, to be used in combination with persulfate-based hair bleaches or with dyes, lightening, super-lightening products. The composition of the semi-finished product includes hydrogen peroxide in various proportions plus other substances. The oxidising composition (first product) is required to be combined with bleaching products of various dyes (second product) in an emulsion, wherein the pH of the emulsion becomes strongly alkaline, preferably a pH between 8 and 11.5. Thus, the compositions work at strong alkaline pH. Besides, there is no data to prove any effectiveness of the compositions.
[0011] US3060097A discloses a composition for bleaching the skin of living creatures. The skin bleaching composition described comprises benzyloxyphenol, sodium hypochlorite, and other constituents. Benzyloxyphenol however does not get metabolized when absorbed into the skin and is associated with instances of irreversible depigmentation simulating vitiligo that is patches of depigmentation often having a hyperpigmented border and enlarging slowly. Additionally, benzyloxyphenol is transported by the lymph system and may cause irreversible depigmentation in areas of the body away from the site of application.
[0012] US11026877B2 relates to a cosmetic composition for bleaching the skin, which includes a) at least one oily plant extract from the Glycyrrhiza genus and b) at least one ascorbic acid ester. The invention further relates to the cosmetic, non-therapeutic use of the cosmetic composition to treat excessive pigmentation, pigmentation disorders, age spots, and/ or post - inflammatory hyper-pigmentation of the skin, and to a method for producing a cosmetic skin - bleaching composition in the form of an O/W or a W/O emulsion, wherein an oily extract from licorice roots is dissolved in the water phase by the addition of an ascorbic acid ester. Such composition comprising herbal extracts may have lower stability on account of presence of herbal extract; Emulsions are known to separate into different phases and can have lower stability.
[0013] The cosmetic industry and consumers are in constant search for hair/skin lightening products that give an even lightening without any harmful effects to hair/skin. One of the issues with lighteners is that it may cause irritation or damage due to strong oxidising systems needed for bleaching / depigmentation. There is therefore a continuing need to provide hair/skin lightening compositions / products having lesser undesirable aspects that can overcome one or more drawbacks of the current products in the market.

OBJECT OF THE INVENTION
[0014] The primary object of the present invitation is to provide an improved oxidant system for lightening and/or colouring of hair comprising phosphate ester(s) or its combinations having log p value in the range of -0.3 to 13.5 or the like in conjunction with lower levels of peroxide.
[0015] Another object of the present invention is to provide an improved oxidant system for lightening and/or colouring of hair comprising phosphate ester(s) or its combinations having log p value in the range of -0.3 to 13.5 or the like in conjunction with lower levels of peroxide that can be used with or without pre-lightening powder for lightening, and with composition containing oxidative dye intermediates for hair colouring.

SUMMARY OF THE INVENTION
[0016] Accordingly, in an aspect the present disclosure provides an improved oxidant system comprising a phosphate ester of specific log p value in conjunction with low level of peroxide to achieve high levels of lightening of hair, skin, and hair colouring that can afford less damage to hair and skin.
[0017] In one aspect, the present disclosure provides a composition for oxidant system comprising (i) at least one phosphate esters with log p value in the range of -0.3 to 13.5 or the like in conjunction with (ii) peroxide about 1% to about 10% by weight.
[0018] In an aspect, the oxidant system can be used with or without a pre-lightening powder to achieve high levels of lightening of hair/skin.
[0019] In one aspect, the oxidant system can be used along with an oxidative hair colouring system comprising of oxidative dye precursors like primary dye intermediates and couplers enhances colouring of keratinic fibres such as hair even when lesser oxidising agents are used, in conjunction with pH modifiers, and other cosmetically acceptable agents including hair/scalp benefiting agents.
[0020] In another aspect, there is provided an oxidant kit comprising at least one phosphate ester with log p values in the range of -0.3 to 13.5, and an oxidant containing peroxide provided in a preparation form selected from but not limited to a crème, shampoo, lotion, gel, foam, and mousse.
[0021] The kit further comprises a pre-lightening powder.
[0022] The kit further comprises an oxidative hair dyeing composition(s).
[0023] In one more aspect, the present disclosure provides a method of lightening the hair comprising applying to hair the composition for an oxidant system `of the present invention comprising at least one phosphate ester, and an oxidising agent provided in a preparation form selected from but not limited to a crème, shampoo, lotion, gel, foam, and mousse; in combination with pre-lightening powder.
[0024] In one more aspect, the present disclosure provides a method of coloring the hair comprising applying to hair composition for an oxidant system of the present invention comprising at least one phosphate ester, and an oxidising agent provided in a preparation form selected from but not limited to a crème, shampoo, lotion, gel, foam, and mousse; in combination with a developer / colorant composition comprising a primary dye intermediate and a coupler in cosmetically acceptable bases.Various features, aspects and advantages of the inventive subject matter will become more apparent from the following detailed description of preferred embodiments.

DETAILED DESCRIPTION
[0025] The following detailed description of the invention is merely exemplary in nature and is not intended to limit the invention or the application and uses of the invention. It is to be understood that the present disclosure is not limited to the details of the embodiments disclosed such for construction and the arrangement of components set forth in the following description. The present disclosure is capable of other embodiments, of being practiced, or of being carried out in various ways. Also, it is to be understood that the phraseology and terminology used herein is for the purpose of description and should not be regarded as limiting.
[0026] All technical and scientific words used herein, unless otherwise defined, have the same meaning as commonly known by one having ordinary ability in the relevant field.
[0027] The words "a" and "an" designate one or more (i.e., at least one) of the article's grammatical objects. Unless otherwise stated, weight is used to determine all percentages and ratios. All percentages and ratios are calculated based on the total final composition unless otherwise indicated.
[0028] As used herein, whether in a transitional phase or the body of a claim, the terms “comprise(s)” and “comprising” are to be interpreted as having an open-ended meaning. That is, the terms are to be interpreted synonymously with the phrases “one or more” or “at least one”. When used in the context of a composition, the term “comprising” means that the process includes at least the recited steps but may include additional steps. When used in the context of a composition, the term “comprising” means that the composition includes at least the recited features or components but may also include additional features or components.
[0029] All composition described herein can be performed in suitable order unless otherwise indicated herein or otherwise clearly contradicted by context. The use of any and all examples, or exemplary language (e.g., “such as”) provided with respect to certain embodiments herein is intended merely to better illuminate the disclosure and does not pose a limitation on the scope of the invention otherwise claimed. No language in the specification should be construed as indicating any non-claimed element essential to the practice of the disclosure.
[0030] Reference throughout this specification to “an embodiment” or “in an embodiment” means that a particular feature, structure, or characteristic described in connection with the embodiment is included in at least one embodiment. Thus, the appearances of the phrases “yet another embodiment” or “in an embodiment” in various places throughout this specification are not necessarily all referring to the same embodiment. Furthermore, the particular features, structures, or characteristics may be combined in any suitable manner in one or more embodiments.
[0031] The numerical values given for various physical parameters, dimensions and quantities are only approximate values and it is envisaged that the values higher than the numerical value assigned to the physical parameters, dimensions and quantities fall within the scope of the disclosure unless there is a statement in the specification to the contrary.
[0032] As used herein the phrase “oxidant system” means a combination of substances that act or is used as oxidizing agents.
[0033] The term developer or oxidant may be used interchangeably and means an oxidising agent.
[0034] The following description includes various specific details and is to be regarded as merely exemplary. Accordingly, those of ordinary skill in the art will recognize that without departing from the scope and spirit of the present disclosure and its various embodiments, there may be any number of changes and modifications to those described herein.
[0035] In an embodiment of the present disclosure there is provided a compositionfor an improved oxidant systemcomprising
(i) at least one oxidant containing peroxide; and
(ii) at least one phosphate ester with log p values in the range of -0.3 to 13.5
in a cosmetically acceptable base in conjunction with pre-lightening powders or oxidative hair dyeing composition(s).
[0036] In an embodiment, the developer/oxidant is comprised in a preparation form selected from but not limited to a crème, shampoo, lotion, gel, foam, and mousse.
[0037] In one embodiment of the present disclosure there is provided a compositionfor an improved oxidant system comprising,
(i) at least one oxidant containing peroxide, specifically hydrogen peroxide in the range of about 1% to about 10% by weight; and
(ii) at least one phosphate ester with log p values in the range of about -0.3 to about 13.5 with concentration from about 0.5% to about 20% by weight
in a cosmetically acceptable base in conjunction with pre-lightening powder(s) or oxidative hair dyeing compositions.
[0038] One more embodiment of the present disclosure, there is provided a composition for an improved oxidant system comprising,
(i) at least one developer/oxidant containing peroxide such as hydrogen peroxide in the range of about 1% to about 10% by weight; and
(ii) at least one phosphate ester with log p value in the range of -0.3 to 13.5 with concentration from about 0.5% to about 20% by weight
in a cosmetically acceptable base in conjunction with pre-lightening powder(s) for lightening / bleaching or with oxidative hair dyeing compositions comprising primary hair dye intermediates and couplers for hair colouring.
[0039] The hydrogen peroxide can be present by weight in the composition at about 1%, 2%, 3%, 4%, 5%, 6%, 7%, 8%, 9%, or 10% or any integer in between.
[0040] The phosphate ester can be present by weight in the composition at about 0.5%, 0,6%, 0.7%, 0.8%, 0.9%, 1%, 2%, 3%, 4%, 5%, 6%, 7%, 8%, 9%, 10%, 11%, 12%, 13%, 14%, 15%, 16%, 17%, 18%, 19%, or 20%, or any integer in between.
[0041] In accordance with the present disclosure the composition for an oxidant system with a lower concentration of oxidising agents required to achieve high levels of lightening with or without pre-lightening powders has a pH between 1.8 to 4.
[0042] According to one embodiment, the composition for an improved oxidant system comprising at least one oxidant containing peroxide; and at least one phosphate ester with log p values in the range of -0.3 to 13.5 is safer in handling, and can also provide a cost advantage.
[0043] Use of lower levels of peroxide for efficient pre-lightening/colouring reduces the formulation cost, since lesser concentration of peroxide is necessary to achieve desired product deliveries.
[0044] In an embodiment of the present disclosure, the oxidising agentis a water soluble per-oxygen oxidizer, or an inorganic per-oxygen material capable of providing peroxide in a preparation selected from cream, shampoo, lotion, gel, mousse, foam or the like. In a preferred embodiment the oxidising agent is hydrogen peroxide, adducts of hydrogen peroxide, inorganic alkali metal peroxide including barium peroxide, sodium peroxide or combination thereof. In an embodiment, the % by weight of the oxidizing agent ranges from about 1% to about 10%.
[0045] In an embodiment of the present disclosure, the phosphate ester(s) with log p values in the range of -0.3 to 13.5 is selected from but not limiting to bis(2-ethylhexyl) phosphate, trimethyl phosphate, triethyl phosphate, triamyl phosphate, tris(2-butoxyethyl) phosphate, or the combination thereof. The phosphate ester is selected from dioleyl phosphate (trade name Crodafos HCE), oleth-5 phosphate (trade name Crodafos O5A), oleth-3 phosphate (trade name Crodafos O3A), potassium cetyl phosphate (trade name Crodafos MCK) or the combination thereof. In an embodiment, the % by weight of the phosphate ester ranges from about 0.5% to about 20%.
[0046] In an embodiment of the present disclosure, the oxidative hair lightening / bleaching system comprises oxidiser selected from the group consisting of sodium persulfate, potassium persulfate, ammonium persulfate, sodium percarbonate and combination thereof.
[0047] In an embodiment of the present disclosure, the oxidative dye precursor like primary dye intermediate is selected from the group consisting of p-Phenylenediamine, Toluene 2,5-diamine, N-phenyl p-Phenylenediamine, N,N-bis(2-hydroxyethyl)-p-Phenylenediamine, N-ethyl-N-(2-hydroxyethyl)-p-Phenylenediamine, N-ethyl-N-(2-piperidinoethyl)-p-Phenylenediamine, Hydroxypropyl-bis-(N-hydroxyethyl)-p-Phenylenediamine, 2-(1,2-dihydroxyethyl)-p-Phenylenediamine, 2,2'-(2-(4-aminophenylamino)ethylazanediyl)-diethanol, 2-chloro-p-Phenylenediamine, 2-(methoxymethyl) p-Phenylenediamine, p-Aminophenol, p-(methylamino)phenol, 4-Amino-3-methylphenol, 2-Amino-5-ethylphenol, 2,4,5,6-tetraminopyrimidine, 1-hydroxyethyl-4,5-diaminopyrazole sulfate, 4,5-diamino-1-methylpyrazole, 4,5-diamino-1-ethylpyrazole, 4,5-diamino-1-hexylpyrazole and 2-[(3-aminopyrazolo[1,5-a]pyridin-2yl)oxy]ethanol hydrochloride, or combination thereof.
[0048] Preferably, the oxidative dye precursor like primary dye intermediate is selected from the group consisting of p-Phenylenediamine, Toluene 2,5-diamine, n,n-bis(2-hydroxyethyl)-p-Phenylenediamine, 2-Chloro-p-Phenylenediamine, 2-(methoxymethyl) p-Phenylenediamine, p-Aminophenol, and 1-hydroxyethyl-4,5-diaminopyrazole sulfate, or combination thereof.
[0049] In an embodiment of the present disclosure, the oxidative dye precursor like coupler is selected from the group consisting of m-Aminophenol, Resorcinol, 2,4-Diaminophenoxyethanol, Hydroxyethyl-3,4-methylenedioxyaniline HCl, 5-Amino-2-Methylphenol, 4-Amino 2-Hydroxytoluene, 1,3-diaminobenzene, and phenyl methyl pyrazolone or combination thereof.
[0050] In another embodiment of the present disclosure, there is provided an improved oxidant system, in which a pre-lightening powder(s) or an oxidative hair dye composition(s) comprising primary hair dye intermediate(s) and coupler(s) in respective cosmetically accepted base is provided separately from the composition of the oxidant systemto be mixed together immediately prior to application to hair.
[0051] In another embodiment of present disclosure, a method for preparing an improved oxidant system for lightening the hair comprises combining at least one phosphate ester, and an oxidant/oxidising agent provided in a preparation form selected from but not limited to a crème, shampoo, lotion, gel, foam, and mousse as one component with a pre-lightening powder as the other component; and mixing together both the components immediately prior to application to hair.
[0052] In another embodiment of present disclosure, a method for preparing an improved oxidant systemfor lightening the hair comprises combining at least one phosphate ester, and an oxidant/oxidising agent provided in a preparation form selected from but not limited to a crème, shampoo, lotion, gel, foam, and mousse as one component with an oxidative hair lightening / bleaching system as the other component; and mixing together both the components immediately prior to application to hair.
[0053] In another embodiment of present disclosure a method for preparing an improved oxidant systemfor lightening the hair comprises combining at least one phosphate ester, and an oxidant/oxidising agent provided in a preparation form selected from but not limited to a crème, shampoo, lotion, gel, foam, and mousse as one component with a developer / colorant composition comprising oxidative dye precursor like a primary dye intermediate, and coupler in cosmetically acceptable base(s) as the other component; and mixing together all the components immediately prior to application to hair.
[0054] In some other embodiment of the present disclosure, there is provided an oxidant kit comprising at least one phosphate ester, and an oxidising agent provided in a preparation form selected from but not limited to a crème, shampoo, lotion, gel, foam, and mousse.
[0055] In further embodiment of the present disclosure, there is provided a kit comprising at least one phosphate ester, and an oxidising agent provided in a preparation form selected from but not limited to a crème, shampoo, lotion, gel, foam, and mousse as one component; and a pre-lightening powder as the other component,
[0056] In an embodiment of the present disclosure, there is provided a kit comprising at least one phosphate ester, and an oxidising agent provided in a preparation form selected from but not limited to a crème, shampoo, lotion, gel, foam, and mousse as one component; and pre-lightening powders or oxidative hair dyeing composition(s) as the other component.
[0057] In another aspect, there is provided an oxidant kit comprising at least one phosphate ester with log p values in the range of -0.3 to 13.5, and an oxidant containing peroxide provided in a preparation form selected from but not limited to a crème, shampoo, lotion, gel, foam, and mousse.
[0058] The kit further comprises a pre-lightening powder, hair lightening / bleaching system.
[0059] The kit further comprises an oxidative hair dyeing composition(s) including oxidative dye precursor like a primary dye intermediate, and coupler in cosmetically acceptable base(s).A further embodiment of the present disclosure relates to a use of an improved oxidant system comprising a lesser oxidising agent and a phosphate ester with log p values in the range of -0.3 to 13.5 to afford less damage to hair/skin.
[0060] In one more embodiment of the present invention, there is provided a method of lightening the hair comprising applying composition for an oxidant system, or an oxidant kit comprising at least one phosphate ester, and an oxidising agent provided in a preparation forms elected from but not limited to a crème, shampoo, lotion, gel, foam, and mousse; in combination with pre-lightening powder.
[0061] In further embodiment of the present invention, there is provided a method of lightening the hair comprising applying composition for an oxidant system, or an oxidant kit comprising at least one phosphate ester, and an oxidising agent provided in a preparation form selected from but not limited to a crème, shampoo, lotion, gel, foam, and mousse; in combination with a colorant composition comprising a primary dye intermediate and a coupler in cosmetically acceptable bases.
[0062] An embodiment of present disclosure provides a method for lightening of hair comprising
(a) providing an oxidant system comprising at least one oxidant containing lower peroxide levels comprised in a preparation form selected from crème, shampoo, lotion, gel, foam, mousse, or the like; and at least one phosphate ester with log p values in the range of -0.3 to 13.5;
(b) intimately mixing the said oxidant system with a pre-lightening powder wherein the oxidant system is provided separately or as a compartmentalized container including a sachet in a kit to provide a ready to use hair lightening composition mix;
(c) applying the mixture uniformly on dry clean hair swatches and then waiting for upto about 45 minutes as developmental time with or without aluminium foil.
[0063] An embodiment of present disclosure provides a method of coloring of hair with reduced peroxide involving the steps of
(a) providing an oxidant system comprising at least one oxidant containing lower peroxide levels comprised in a preparation form selected from crème, shampoo, lotion, gel, foam, mousse, or the like; and at least one phosphate ester with log p values in the range of -0.3 to 13.5;
(b) intimately mixing the said oxidant system with oxidative dye formulation wherein both the components are provided separately or as a compartmentalized container including sachet in the kit to provide for ready to use oxidative hair coloring composition mix; and
(c) applying the mixture uniformly on dry hair and then waiting for upto about 45 minutes as developmental time.
[0064] The method for lightening or coloring of hair includes steps of:
(a) washing hair with water after the specified time of applying the oxidant system of the present invention either alone or in combination with other preparation, shampooing with non-conditioning shampoo; and
(b) washing the hair followed by drying.
[0065] The compositions, kits and method involving the oxidant system comprising phosphate ester with log p values in the range of -0.3 to 13.5 and a lower concentration of oxidant/oxidising agents is capable of achieving high levels of lightening with and without pre-lightening powders; as well as achieving 100% grey hair or bleached hair coverage when used with a hair colouring composition.
[0066] Aspects of the present disclosure are further understood in light of the following examples, which should not be considered as limiting the scope of the present disclosure.

EXAMPLES
[0067] The present disclosure is further explained in the form of the following examples. However, it is to be understood that the foregoing examples are merely illustrative and are not to be taken as limitations upon the scope of the invention. Various changes and modifications to the disclosed embodiments will be apparent to those skilled in the art. Such changes and modifications may be made without departing from the scope of the invention.
[0068] All the tabulated concentrations in the tables are in the form of free base and recorded as “weight%” (wt%) of the total composition.
QUALITATIVE AND QUANTITATIVE DETERMINATIONS
Colour Uptake (DL)
[0069] Colour measurements were undertaken using spectrophotometer and the results were based on the L values.
LA = L value obtained after colouring/lightening;
LB = L value obtained before colouring/lightening;

Colour Uptake or DL (or ?L) = The L value before colouring/lightening – L value after colouring/lightening (LB – LA)
For hair lightening / bleaching:
[0070] The prepared oxidant systems were mixed with pre-lightening powders in 1:2 ratio was applied on brown hair swatches. Post-application, the swatches were left in contact with mixture for 30-45 minutes and then washed. After colouring, The LA values were recorded. The colour uptake (DL) values were calculated.
For hair colouring:
[0071] The prepared oxidant systems were mixed with colorant composition in 1:1 ratio and were applied on grey hair swatches. Post-application, the swatches were left in contact with mixture for 10-30 minutes and then washed. After colouring, The LA values were recorded. The colour uptake (DL) values were calculated.
Lipophilicity
[0072] An important physicochemical property for any molecule is its Lipophilicity. This single property dictates many aspects of the performance of the molecule/s in a complex system; it influences properties solubility, absorption, membrane permeability, distribution in a biphasic system such as an emulsion system.
[0073] The partition coefficient (P = [organic]/[aqueous]) is a measure of lipophilicity and is defined as the ability of a compound to differentially dissolve in a mixture of water and lipids/organic solvents. In reality, P is computed to help prioritise the synthesis of the right compounds. The log10 value of P (LogP) is a constant and is a negative value for hydrophilic compounds (higher affinity for the aqueous phase), a positive value for lipophilic compounds (higher affinity for the lipid/organic solvent phase), and zero (0) value for compounds which partition equally between lipid and aqueous phases. For example, if LogP = 1 it means that the partitioning of the compound is 10 times more in lipid/organic solvent phase compared to aqueous phase.
[0074] Lipophilicity is often calculated using a collection of training data-set available for molecules and fragments that contribute to sub-structures and functional groups of molecules. Basically, there are three different approaches to calculate LogP; 1) Atomic method which considers the contribution of each atom of molecule in a purely additive manner. 2) Fragment method which considers contribution from sub-structures and functional groups along with accounting for proximity effects. 3) Property method which involves computational predictions.
[0075] One aspect that needs to be kept in mind while using LogP value is that it only correctly describes the partition coefficient of uncharged molecules. Overall, lipophilicity is a critical parameter that dictates the efficacy and success of a molecule in a biphasic system. To understand the influence of lipophilicity on the effectiveness of different phosphate esters, their lipophilicity as reflected in their logP values were considered.
EXPERIMENTAL DETAILS
[0076] The compositions of the hydrogen peroxide-based oxidation system with varying concentration of hydrogen peroxide were prepared as a cream / lotion.
Example 1
Oxidant System
[0077] The base compositions used for the oxidant system as per the present invention is given in Table 1.
Table 1: General base formulation for Oxidant System
Ingredients Wt%
Oil Phase Ingredients Cetearyl alcohol 2.50
Lauryl alcohol 0.63
Phosphate esters As per the relevant experiments (refer to Tables)
Water Phase Ingredients Sodium laureth sulphate 2.00
Etidronic acid 1.50
2,6-Dicarboxypyridine 0.10
Ethanolamine 0.33
Hydrogen peroxide (50% strength) As per the relevant experiments (refer to Tables)
Water Q.S to 100

[0078] The pH of the composition varied between 1.8 and 4, depending on the phosphate ester and its concentration.
[0079] The detailed general procedure of preparation of the oxidant system is given below.
General method for preparation of hydrogen peroxide oxidant:
1. Oil phase ingredients were heated to a temperature of 75?C.
2. When the oil phase ingredients completely melted, sodium laureth sulphate and water (50% of the total quantity) were added to the mixture at 75?C and stirred for 10 min to form the emulsion.
3. Once the mixture cooled down to 55?C, the chelating agents (Etidronic acid, 2,6-Dicarboxypyridine) dispersed in ethanolamine and water (15% of total water) were added. Stirring was continued till the temperature dropped to about 35?C.
4. After the emulsion was cooled below 35?C, hydrogen peroxide along with the remaining water was added to the emulsion. It was then stirred well to ensure complete mixing. The preparation was used for further experiments.
Example 2
Pre-lightening Powder
[0080] The base compositions of the pre-lightening powder used in conjunction with the oxidant system of the present invention is given in Table 2.

Table 2: Composition of Pre-Lightening Powder
Experiment. No. / Composition No.: 1
Ingredients Wt%
1 Powder Base Brown Talc 7.83
2 Sodium stearate 4.5
3 Silica gel 3.96
4 Liquid paraffin (Light) 2.7
5 Magnesium carbonate hydroxide 1.8
6 Disodium EDTA 0.81
7 Xanthan gum 0.45
8 Guar Hydroxypropyltrimonium chloride 0.45
9 CI770007 0.12
10 Sodium silicate alkaline powder Q.S to 100
11 Oxidants Ammonium persulfate 18.9
12 Potassium persulfate 13.5

[0081] The detailed general method of preparation of the pre-lightening powder is given below.
General method for preparation of pre-lightening powder:
1. All the ingredients of the powder base were weighed and blended together. Ingredients might be added in the mixing vessel in any order.
2. The oxidants were also weighed and added one at a time, in any order, to the powder base. It was then thoroughly mixed to form a uniform mixture.
While the oxidants may be added even before complete mixing in Step 1, it is necessary to ensure that ammonium persulfate and potassium persulfate are added only at the end and the entire mixture is thoroughly mixed.
Example 3
Hair Colourant
[0082] The base compositions of the hair colourant used in conjunction with the oxidant system of the present invention is given in Table 3.
Table 3: Composition of Hair Colorant (Natural Black)
Experiment. No/ Composition No.: 2
Ingredients Wt%
Oil phase ingredients Cocamide MEA 3.5
Lauryl glucoside 5
Rheology modifier Acrylates/C10-30 alkyl acrylate cross-polymer 0.68
Salt cum dye phase ingredients Sodium sulfite 0.5
Ethanolamine 7
p-Phenylenediamine 2.5
m-Aminophenol 1
Resorcinol 0.5
2,4-Diaminophenoxyethanol HCl 1
Conditioning agents/Fragrance Cetyl hydroxyethyl cellulose 0.05
Acrylamidopropyltrimonium Chloride/Acrylamide Copolymer 0.05
Fragrance 0.5
Water 77.72

[0083] The detailed general method of preparation of the hair colourant is given below.
General method of preparation of the hair colourant (composition no. 2):
1. Oil phase ingredients such as cocamide MEA and lauryl glucoside were heated to a temperature of 78?C till these ingredients had completely melted.
2. The rheology modifiers were dispersed in 20% of total water and were added to the molten mixture at 78?C and stirred for 10 min.
3. The salt cum dye phase intermediates were dissolved in 15 % of total water-ethanolamine mixture and subsequently added to the emulsion. The mixture was then agitated and cooled to 45?C.
4. The conditioning agents (Cetyl hydroxyethyl cellulose and Acrylamidopropyltrimonium Chloride/Acrylamide Copolymer) and remaining ingredients (fragrance and remaining water) were added and agitated for a further period of 5 min. It is then cooled to 30?C. It was now ready for use.

Example 4
Application To Hair
[0084] The different compositions prepared were used for application to hair for either pre-lightening or colouring purposes. These procedures are described in Examples 4 to Example 6.
General method for preparation of hair swatches:
[0085] For the preparation of grey hair tresses / swatches, the following procedure was followed.
1. The hair was washed prior to use with a non-conditioning shampoo and then dried in air.
2. Hair swatches – each weighing 5g - were bunched together and firmly anchored / tightened for use in the experiments.
3. The tresses were sorted based on the L values before colouring. L values of the grey hair swatches selected for the study were 55.5 ± 5 and L values of brown/black hair swatches were 19 ± 2.5.
Example 5
Process of bleaching and evaluation of hair / hair swatches using oxidant system and pre-lightening powder
[0086] It is recommended to use hand gloves to cover the hands to prevent exposure to the chemicals. The entire process involved 3 steps of application, development and washing to make the hair swatches ready for evaluation. For hair lightening / bleaching, the prepared oxidant system was applied on brown hair swatches. Post application, the swatches were left in contact with it for 30-45 minutes wrapped under aluminium foil and then washed. Similarly, the oxidant system as per Example 1 was mixed with pre-lightening powder as per Example 2 in 1:2 ratio and was applied on brown hair swatches. Post-application, the swatches were left in contact with mixture for 30-45 minutes wrapped under aluminium foil and then washed. After washing and drying, The LA values were recorded. The difference in hair lightening (DL) values were calculated

Example 6
Process of colouring and evaluation of hair / hair swatches using oxidant system and colourant composition
[0087] It is recommended to use hand gloves to cover the hands to prevent staining of hands as well as to prevent exposure to the chemicals. The entire process involved 3 steps of application, development and washing to make the hair swatches ready for evaluation. For hair colouring, the prepared oxidant system as per Example 1 was mixed with hair colorant as per Example 3 in 1:1 ratio and was applied on grey hair swatches. Post-application, the swatches were left in contact with mixture for 10-30 minutes and then washed. After colouring, The LA values were recorded. The colour uptake (DL) values were calculated.

Example 7
% improvement in lightening
[0088] % Improvement in lightening was calculated based on the following formula

*100

Observations and inferences
Table 4: Phosphate esters and the corresponding log P values
Trade Name log P
2-Ethylhexyl diphenyl phosphate 6.3
Bis(2-ethylhexyl) phosphate 5.73
Trimethyl phosphate -0.46
Triethyl phosphate 1.11
Triamyl phosphate 5.73
Tris(2-butoxyethyl)phosphate 3.8
Crodafos HCE Oleth-5 phosphate 7.7
Dioleyl phosphate 13.15
Crodafos O3A Oleth-3 phosphate 5.9
Crodafos O5A Oleth-5 phosphate 7.7
Crodafos MCK Potassium cetyl phosphate 6.4
Crodafos CS20A Cetearyl Alcohol 6.73
Ceteth-20 Phosphate 4.94
Dicetyl Phosphate 14.5

Table 4 shows the log p values of the phosphate esters which is used in the subsequent experiments.
% Improvement in lightening with phosphate esters:
[0089] With hydrogen peroxide-based oxidants, hair lightening was found to be better than the control samples (as shown in Table 5). Thus, it could be seen that the combination of the oxidant system with phosphate esters showed improved efficacy.
Table 5 : Improvement in hair lightening upon use of phosphate esters without any pre-lightening powder
Experiment No. 3 4 5 6 7 8 9 10 11 12
Concentration (%)
Key Ingredients (Table 1; Experiment: 1)
Oleth-5 Phosphate (and) Dioleyl Phosphate (Crodafos HCE) 0 0 0 0 0 1 1 1 1 1
Hydrogen peroxide (50%) 2 6 8 12 18 2 6 8 12 18
Results
Without pre-lightener Before Lightening (LB) 19.9 19.2 18.6 19.1 19.1 20.0 19.0 18.6 18.9 18.8
After Lightening (LA) 21.6 21.0 21.7 20.2 22.5 22.9 21.5 23.6 20.5 23.0
DL (LA-LB) 1.7 1.9 3.1 1.1 3.4 3.0 2.5 5.0 1.6 4.2
Improvement in Hair lightening (%) 76.2 33.8 61.3 43.4 24.4

% Improvement in lightening with phosphate esters and in presence of pre-lightener powder:
[0090] In further experiments a pre-lightener powder was incorporated in the hydrogen peroxide-based oxidant system. For evaluating the effectiveness, in the experiments as per Example 5, the pre-lightener to the hydrogen peroxide oxidant system ratio was 1:2. The results are given in Table 6.
Table 6 : Improvement in hair lightening upon use of phosphate esters with pre-lightening powder
Experiment No 13 14 15 16 17 18 19 20 21 22
Concentration (%)
Key Ingredients (Table 1; Experiment: 1)
Oleth-5 Phosphate (and) Dioleyl Phosphate
(Crodafos HCE) 0 0 0 0 0 1 1 1 1 1
Hydrogen peroxide (50%) 2 6 8 12 18 2 6 8 12 18
Results
With Pre-lightener (1:2 mixing ratio) Before Lightening (LB) 18.4 19.7 17.6 17.9 18.0 18.3 17.9 18.5 18.4 18.1
After Lightening (LA) 25.1 25.6 25.9 43.8 48.1 28.4 29.7 35.5 53.4 56.2
DL (LA-LB) 6.7 5.9 8.3 25.9 30.1 10.0 11.8 17.0 35.0 38.0
Improvement in Hair lightening (%) 49.8 100.3 104.8 35.1 26.2

[0091] With pre-lightener powder, control sample containing 2% and 6% H2O2 provided only a DL of 6.7 and 5.9, respectively (Experiments13 and 14). But oxidant compositions with Crodafos HCE containing same levels of H2O2 provided higher levels of lightening where the DL values were 10 and 11.8, respectively (Experiments18-19). The same trend was seen for 12% H2O2 without Crodafos HCE, where the DL was 25.9 and with Crodafos HCE, the DL was 35 (Experiments 11 and 16). 18% H2O2 oxidant system without and with Crodafos HCE gave DL of 30.1 and 38, respectively (Experiments 17 and 22). Again, with Crodafos HCE, there was clear improvement in hair lightening (Table 6). With incorporation of Crodafos HCE, the concentration of H2O2 required to bring about better hair lightening is lesser than that without Crodafos HCE. As can be seen from Experiment 17, where there is no Crodafos HCE in the composition, DL was 30.1 with 18% H2O2. But, with the incorporation of Crodafos HCE, even with 12% H2O2, DL of 35 was observed (Experiment 21) which was even better.
[0092] This shows that what can be achieved at 18% H2O2 (50% strength) (equivalent to 9% H2O2 (100% strength)), without Crodafos HCE, was achieved even more efficaciously at 12% H2O2 (50% strength) (equivalent to 6% H2O2 (100% strength)), with Crodafos HCE (DL of 30.1 vs 35; absolute L value of 48.1 vs 53.4). This can be seen in other examples too. This clearly indicates the fact that Crodafos HCE incorporation results in lowering of peroxide levels for higher lifting.
[0093] From the above experiments it is very clear that phosphate esters improve the hair lightening with lower levels of peroxide with or without pre-lightener powder.
% Improvement in lightening with phosphate esters of different Log p values:
[0094] Log p value is a measure of a compound's lipophilicity, or its preference for dissolving in an organic solvent (like octanol) versus water. In order to establish whether all the phosphate esters impart the improvement, phosphate esters were selected based on Log p values. Log p values of the representative phosphate esters are tabulated in Table 4. Results are tabulated in the following tables (7a-7e).
Table 7a: Improvement in hair lightening upon use of phosphate esters with various log p Values
Experiment No 16 17 23 24 25 26 27 28 29 30 31 32
Concentration (%)
Key Ingredients (Table 1; Experiment: 1)
Trimethyl phosphate 0 0 0.05 0.05 1 1 5 5
Triethyl phosphate 0 0 1 1 5 5
Hydrogen peroxide (50%) 12 18 12 18 12 18 12 18 12 18 12 18
Results
With Pre-lightener (1:2 mixing ratio) Before Lightening (LB) 17.9 18.0 18.7 18.8 20.0 18.4 18.9 19.3 20.5 18.9 21.1 20.5
After Lightening (LA) 43.8 48.1 44.6 45.1 49.6 57.2 53.8 51.2 47.5 51.8 48.4 56.9
DL (LA-LB) 25.9 30.1 25.9 26.3 29.6 38.8 35.0 31.9 27.0 32.9 27.3 36.4
Improvement in Hair lightening (%) -0.06 -12.7 14.2 28.8 35.0 5.9 4.2 9.1 5.3 20.9

[0095] Trimethyl phosphate has a log p value of -0.46, indicating that it has more affinity towards water. When 0.05% of trimethyl phosphate was used, as seen in Table 7a, there was no improvement in lightening (Experiment 23 and 24). But as the concentration was increased, hair lightening improved to a DL value of 38.8 (Experiment 25-28). Triethyl phosphate with a log p value of 1.1 also showed significant improvement in hair lightening to a DL value of 36.4 (Experiment29-32).
% Improvement in lightening with phosphate esters of different Log p values, and in presence of pre-lightener powder:
[0096] Table 7b depicts the use of Tris(2-butoxyethyl)phosphate and 2-ethylhexylphosphate, having log p values of 3.8 and 5.73, respectively. Both the phosphate esters improved the hair lightening when used in combination with pre-lightener powder.
Table 7b: Improvement in Hair Lightening Upon Use of phosphate esters with various log p Values
Experiment No 16 17 33 34 35 36 37 38 39 40 41 42 43 44
Concentration (%)
Key Ingredients (Table 1; Experiment: 1)
Tris(2-butoxyethyl)phosphate 0 0 0.05 0.05 1 1 5 5 10 10
2-ethylhexyl phosphate 0 0 0.05 0.05 1 1
Hydrogen peroxide (50%) 12 18 12 18 12 18 12 18 12 18 12 18 12 18
Results
With Pre-lightener (1:2 mixing ratio) Before Lightening (LB) 17.9 18.0 20.8 21.8 20.0 20.9 20.5 20.3 19.9 20.1 19.1 19.0 18.9 20.1
After Lightening (LA) 43.8 48.1 45.1 54.9 46.4 54.5 51.5 56.9 54.9 50.7 44.5 50.6 46.8 63.1
DL (LA-LB) 25.9 30.1 24.2 33.1 26.5 33.6 30.9 36.6 35.1 30.6 25.5 31.6 27.9 43.0
Improvement in Hair lightening (%) 6.4 9.8 2.2 11.6 19.5 21.5 35.4 1.6 1.8 4.9 7.7 42.9

[0097] The percentage of improvement increased with increase in concentration of Tris(2-butoxyethyl)phosphate when 12% of hydrogen peroxide was used (Experiments 33, 35, 37, and 39). The lightening improvement was -6.4% with 0.05% of Tris(2-butoxyethyl)phosphate which gradually increased to 2.2% with 1wt%, 19.5% with 5 wt% and 35.4% with 10 wt% of Tris(2-butoxyethyl)phosphate. For 2-ethylhexyl phosphate, hair lightening was found to improve across both 12% and 18%, the improvement was more significant for 18% hydrogen peroxide (Experiments 42 and 44). With 1% 2-ethylhexyl phosphate percentage improvement in lightening was 42.9% with 18% of hydrogen peroxide.
Table 7c: Improvement in hair lightening upon use of phosphate esters with various log p Values
Experiment No 16 17 45 46 47 48 49 50 51 52 53 54 55 56
Concentration (%)
Key Ingredients (Table 1; Experiment: 1)
Oleth-3 phosphate (Crodafos O3A) 0 0 0.05 0.05 0.5 0.5 1 1 5 5 10 10 20 20
Hydrogen peroxide (50%) 12 18 12 18 12 18 12 18 12 18 12 18 12 18
Results
With Pre-lightener (1:2 mixing ratio) Before Lightening (LB) 17.9 18.0 19.2 18.0 19.8 18.7 20.3 19.3 19.4 19.1 19.1 19.3 19.3 19.4
After Lightening (LA) 43.8 48.1 44.6 48.8 49.1 50.1 48.2 50.8 48.1 52.1 48.9 50.9 45.7 51.6
DL (LA-LB) 25.9 30.1 25.4 30.8 29.3 31.4 28.0 31.5 28.6 33.1 29.8 31.6 26.5 32.2
Improvement in Hair lightening (%) -1.8 2.2 13.0 4.2 8.1 4.4 10.6 9.8 15.0 5.0 2.1 6.8

[0098] Table 7C shows the improvement in hair lightening when Oleth-3-phosphate with a log p value of 5.9 was used. Concentration of Oleth-3 phosphate was varied between 0.05 to 20%. In all the cases there was improvement in hair lightening. This clearly demonstrates the fact that incorporation of phosphate ester even at 20% delivers significant improvement in hair lightening. With 0.05 wt% of Oleth-3 phosphate, for 12% hydrogen peroxide the improvement was – 1.8%, whereas for 18% hydrogen peroxide, the improvement was 2.2% (Experiments 45 and 46). As the concentration of phosphate ester increased, improvement in lightening also increased. Though there was improvement in lightening as the concentration was increased to 20%, the effect was found to be less (Experiments 55 and 56).
[0099] Similar trend was seen for Oleth-5 phosphate having log p value of about 7.7 as shown in Table 7d.
Table 7d: Improvement in Hair Lightening Upon Use of phosphate esters with various log p Values
Experiment No 16 17 57 58 59 60 61 62 63 64 65 66 67 68
Concentration (%)
Key Ingredients (Table 1; Experiment: 1)
Oleth-5 phosphate (Crodafos O5A) 0 0 0.05 0.05 0.5 0.5 1 1 5 5 10 10 20 20
Hydrogen peroxide (50%) 12 18 12 18 12 18 12 18 12 18 12 18 12 18
Results
With Pre-lightener (1:2 mixing ratio) Before Lightening (LB) 17.9 18.0 18.6 19.3 18.5 20.0 18.7 19.4 20.8 19.5 19.8 19.2 20.2 19.7
After Lightening (LA) 43.8 48.1 44.9 49.1 45.8 50.1 49.5 51.5 56.4 53.8 49.3 56.1 52.6 52.3
DL (LA-LB) 25.9 30.1 26.3 29.8 27.3 30.1 30.9 32.1 35.6 34.3 29.5 36.9 32.4 32.6
Improvement in Hair lightening (%) 1.6 -1.2 5.4 0.0 19.1 6.5 37.4 14.0 13.9 22.6 25.2 8.3

[00100] Similar trend was seen for Crodafos MCK having log p value of about 6.4 as shown in Table 7e.
Table 7e: Improvement in Hair Lightening Upon Use of phosphate esters with various log p Values
Experiment No 16 17 69 70 71 72 73 74
Concentration (%)
Key Ingredients (Table 1; Experiment: 1)
Potassium cetyl phosphate (Crodafos MCK) 0 0 1 1 5 5 10 10
Hydrogen peroxide (50%) 12 18 12 18 12 18 12 18
Results
With Pre-lightener (1:2 mixing ratio) Before Lightening (LB) 17.9 18.0 19.9 19.5 19.0 20.3 19.6 20.3
After Lightening (LA) 43.8 48.1 48.5 50.9 49.2 52.1 52.2 54.3
DL (LA-LB) 25.9 30.1 28.7 31.4 30.2 31.8 32.6 34.0
Improvement in Hair lightening (%) 10.7 4.1 16.5 5.6 25.7 12.9

[00101] For mixture of phosphate esters, the impact in hair lightening is demonstrated in Tables 8 and 9.

Table 8: Impact in hair lightening upon use of combination of phosphate esters
Experiment No 16 17 75 76 77 78 21 22 79 80
Concentration (%)
Key Ingredients (Table 1; Experiment: 1)
Oleth-5 Phosphate (and) Dioleyl Phosphate (Crodafos HCE) 0 0 0.25 0.25 0.5 0.5 1 1 5 5
Hydrogen peroxide (50%) 12 18 12 18 12 18 12 18 12 18
Results
With Pre-lightener (1:2 mixing ratio) Before Lightening (LB) 17.9 18.0 18.3 19.2 19.4 18.6 18.4 18.1 19.6 19.2
After Lightening (LA) 43.8 48.1 43.5 50.3 45.6 49.0 53.4 56.2 46.5 51.4
DL (LA-LB) 25.9 30.1 25.2 31.1 26.3 30.5 35.0 38.0 26.9 32.2
Improvement in Hair lightening (%) -2.8 3.1 1.3 1.1 35.1 26.2 3.7 6.9

[00102] For Crodafos HCE, which is a combination of Oleth-5-phosphate and Dioleyl phosphate showed concentration dependent improvement in hair lightening (Table 8). With 1%, the improvement was highest for 12 and 18% hydrogen peroxide containing oxidant composition (Experiments 21and 22). The percentage improvement was 35.1 and 26.2, respectively.

Table 9: Impact in hair lightening upon use of combination of phosphate esters
Experiment No 16 17 81 82
Concentration (%)
Key Ingredients (Table 1; Experiment: 1)
Cetearyl Alcohol (and) Ceteth-20 Phosphate (and) Dicetyl Phosphate (Crodafos CS20A) 0 0 1 1
Hydrogen peroxide (50%) 12 18 12 18
Results
With Pre-lightener (1:2 mixing ratio) Before Lightening (LB) 17.9 18.0 18.5 18.6
After Lightening (LA) 43.8 48.1 27.3 41.6
DL (LA-LB) 25.9 30.1 8.8 23.0
Improvement in Hair lightening (%) -66.0 -23.7

[00103] But with phosphate ester with high lipophilicity, the impact was found to be negative indicating decrease in hair lightening as can be seen from Table 9 (Experiments 81and 82). The lightening significantly reduced by 66% and 23.7%, respectively with 12 and 18% hydrogen peroxide.
Example 8
% improvement in hair colouring
Table 10: Improvement in hair colouring without and with Crodafos HCE
Experiment Details Components Observation
Experiment/Composition Expt 2 Expt 5 Expt 10 LB LA Difference (LB-LA)
No. 83(withoutCrodafos HCE) 50.0% 50.0% - 54.55 28.16 26.39
No. 84(withCrodafos HCE) 50.0% - 50.0% 54.78 17.30 37.48
Expt = Experiment
[00104] For studies with hair colouring, containing oxidant systems of 8% H2O2, Experiment 83 had the oxidant composition without Crodafos HCE (Experiment5) which was combined with colouring composition (Experiment 2). Similarly, Experiment 84 had the oxidant composition containing oxidant systems of 8% H2O2and with Crodafos HCE (Experiment 10) which was combined with colouring composition (Experiment 2) Experiment 5 and Experiment 10 without and with Crodafos HCE, was used for hair colouring composition (Table 10). Without Crodafos HCE (Experiment83), grey coverage was moderate and had a LA value of 28.16 with a DL value of 26.39, whereas with Crodafos HCE (Experiment 84), there was 100% grey coverage and had a LA value of 17.30 with DL value of 37.48. Thus, combinations with phosphate ester (Crodafos HCE) enhanced the effectiveness of the oxidant system.
[00105] Those skilled in the art will recognize, or be able to ascertain using no more than routine experimentation, many equivalents to the specific embodiments of the invention described herein. Such equivalents are intended to be encompassed by the following claims.
,CLAIMS:1. A composition for an improved oxidant system comprising
(i) at least one oxidant containing peroxide; and
(ii) at least one phosphate ester with log p values in the range of -0.3 to 13.5
in a cosmetically acceptable base in conjunction with pre-lightening powders or oxidative hair dyeing composition(s).

2. The composition as claimed in claim 1, wherein, the developer/oxidant containing peroxide is hydrogen peroxide present from 1% to 10% by weight.

3. The composition as claimed in claim 1, wherein, the oxidant is comprised in a preparation form selected from but not limited to a crème, shampoo, lotion, gel, foam, and mousse.

4. The composition as claimed in claim 1, wherein, the phosphate ester with log p values in the range of about -0.3 to about 13.5 is present in concentration from 0.5% to 20% by weight.

5. The composition as claimed in any one of claims 1 to 4, wherein the composition includes pre-lightening powder(s) for lightening / bleaching of hair.

6. The composition as claimed in any one of claims 1 to 4, wherein the composition includes oxidative hair dyeing composition(s) comprising oxidative dye precursor like primary hair dye intermediate(s), and coupler(s) for hair colouring.

7. The composition as claimed in claim 6, wherein the primary hair dye intermediate(s) and coupler(s) in respective cosmetically accepted base is provided separately from the composition of the oxidant system.
8. The composition as claimed in any one of claims 1 to 4, wherein the oxidant is a water soluble per-oxygen oxidizer, or an inorganic per-oxygen material capable of providing peroxide.

9. The composition as claimed in claim 8, wherein the oxidant is selected from hydrogen peroxide, adducts of hydrogen peroxide, inorganic alkali metal peroxide including barium peroxide, and sodium peroxide.

10. The composition as claimed in any one of claims 1 to 4, wherein the phosphate ester(s) with log p values in the range of -0.3 to 13.5 is selected from bis(2-ethylhexyl) phosphate, trimethyl phosphate, triethyl phosphate, triamyl phosphate, tris(2-butoxyethyl) phosphate, dioleyl phosphate, oleth-5 phosphate, oleth-3 phosphate, and potassium cetyl phosphate, or the combination thereof.

11. The composition as claimed in claim 5, wherein the pre-lightening powder(s) for lightening / bleaching of hair includes oxidiser is selected from the group consisting of sodium persulfate, potassium persulfate, ammonium persulfate, and sodium percarbonate.

12. The composition as claimed in claim 6, wherein the primary dye intermediate is selected from the group consisting of p-Phenylenediamine, Toluene 2,5-diamine, n-phenyl p-Phenylenediamine, n,n-bis(2-hydroxyethyl)-p-Phenylenediamine, n-ethyl-n-(2-hydroxyethyl)-p-Phenylenediamine, n-ethyl-n-(2-piperidinoethyl)-p-Phenylenediamine, hydroxypropyl-bis-(n-hydroxyethyl)-p-Phenylenediamine, 2-(1,2-dihydroxyethyl)-p-Phenylenediamine, 2,2'-(2-(4-aminophenylamino)ethylazanediyl)-diethanol, 2-chloro-p-Phenylenediamine, 2-(methoxymethyl) p-Phenylenediamine, p-Aminophenol, p-(methylamino)phenol, 4-amino-3-methylphenol, 2-amino-5-ethylphenol, 2,4,5,6-tetraminopyrimidine, 1-hydroxyethyl-4,5-diaminopyrazole sulfate, 4,5-diamino-1-methylpyrazole, 4,5-diamino-1-ethylpyrazole, 4,5-diamino-1-hexylpyrazole and 2-[(3-aminopyrazolo[1,5-a]pyridin-2yl)oxy]ethanol hydrochloride.

13. The composition as claimed in claim 12, wherein the primary dye intermediate is selected from the group consisting of p-Phenylenediamine, Toluene 2,5-diamine, n,n-bis(2-hydroxyethyl)-p-Phenylenediamine, 2-Chloro-p-Phenylenediamine, 2-(methoxymethyl) p-Phenylenediamine, p-Aminophenol, and 1-hydroxyethyl-4,5-diaminopyrazole sulfate, or combination thereof.

14. The composition as claimed in claim 6, wherein the coupler is selected from the group consisting of m-aminophenol, resorcinol, 2,4-diaminophenoxyethanol, hydroxyethyl-3,4-methylenedioxyaniline HCL, 5-amino-2-methylphenol, 4-amino 2-hydroxytoluene, 1,3-diaminobenzene, and phenyl methyl pyrazolone or combination thereof.

15. A method of lightening the hair comprising applying to hair the composition for an oxidant system as claimed in any one of claims 1 to 14 comprising at least one phosphate ester, and an oxidising agent provided in a preparation form selected from but not limited to a crème, shampoo, lotion, gel, foam, and mousse; in combination with pre-lightening powder.

16. The method for lightening of hair as claimed in claim 15 comprising the steps of:
(a) providing an oxidant system comprising at least one oxidant containing lower peroxide levels comprised in a preparation form selected from crème, shampoo, lotion, gel, foam, mousse, or the like; and at least one phosphate ester with log p values in the range of -0.3 to 13.5;
(b) intimately mixing the said oxidant system with a pre-lightening powder wherein the oxidant system is provided separately or as a compartmentalized container including a sachet in a kit to provide a ready to use hair lightening composition mix;
(c) applying the mixture uniformly on dry clean hair swatches and then waiting for upto about 45 minutes as developmental time with or without aluminium foil.

17. A method of coloring the hair comprising applying to hair composition for an oxidant system as claimed in any one of claims 1 to 14, comprising at least one phosphate ester, and an oxidising agent provided in a preparation form selected from but not limited to a crème, shampoo, lotion, gel, foam, and mousse; in combination with a developer / colorant composition comprising a primary dye intermediate and a coupler in cosmetically acceptable bases.

18. The method of coloring of hair as claimed in claim 15 comprising the steps of
(a) providing an oxidant system comprising at least one oxidant containing lower peroxide levels comprised in a preparation form selected from crème, shampoo, lotion, gel, foam, mousse, or the like; and at least one phosphate ester with log p values in the range of -0.3 to 13.5;
(b) intimately mixing the said oxidant system with oxidative dye formulation wherein both the components are provided separately or as a compartmentalized container including sachet in the kit to provide for ready to use oxidative hair coloring composition mix; and
(c) applying the mixture uniformly on dry hair and then waiting for upto about 45 minutes as developmental time with or without aluminium foil.

19. The method of any one of claims 16 to 18, wherein the method includes steps of:
-washing the hair with water after the specified time of applying the oxidant system of the present invention either alone or in combination with other preparation, shampooing with non-conditioning shampoo; and
- washing the hair followed by drying.

20. An oxidant kit comprising at least one phosphate ester with log p values in the range of -0.3 to 13.5, and an oxidant containing peroxide provided in a preparation form selected from but not limited to a crème, shampoo, lotion, gel, foam, and mousse.

21. The kit as claimed in claim 20, wherein the kit includes a pre-lightening powder.

22. The kit as claimed in claim 20, wherein the kit includes anoxidative hair dyeing composition(s).