Reusable And Electrochemically Active Device For Measurement Of Concentration Of Bioanalytes

Abstract: A reusable and electrochemically active device (100) is provided comprising, detachable electrode arrangement including working electrodes (101a, 101b, 101c, 101d) and a counter electrode (102) that are functionalised with selected electrochemically active receptor(s) that can interact with at least a target bioanalyte. Fluid transportation channels (108a, 108b, 108c, 108d) are formed, to receive biological samples with the at least target bioanalyte and for further transportation to the selected electrode arrangement, preferably in a sequential manner, for measuring the concentrations of the target bioanalytes. Used working electrodes (101a, 101b, 101c, 101d) and a partial portion of the counter electrode 102 are detachable from the device (100). Insulating members (113a, 113b, 113c, 113d, 113e, 113f, 113g) are disposed on the electrode arrangement such that the integrity of the electrical connectivity of the remaining electrode arrangement is retained even after the detachment of the used working electrodes (101a, 101b, 101c, 101d) and a portion of the counter electrode (102). The present invention also provides a point-of-care biosensor (300) and a method to electrochemically measure the concentrations of multiple target bioanalytes and a single bioanalyte repeatedly.

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