Tasipimidine And Cyp2 D6 Inhibitor Combination Treatment

Abstract: The invention relates to co administration a CYP2D6 inhibitor with tasipimidine or a pharmaceutically acceptable salt thereof in order to improve the pharmacokinetic profile of tasipimidine by decreasing its clearance and inter individual variation. The invention also relates to a combination of tasipimidine or a pharmaceutically acceptable salt thereof and a CYP2D6 inhibitor and the use of such a combination for the treatment of a disorder condition or disease where an alpha2A agonist is indicated to be useful for example for use in the treatment of neuropsychiatric disorders.

Patent Information

Application #

Filing Date

04 April 2025

Publication Number

38/2025

Publication Type

INA

Invention Field

CHEMICAL

Status

Email

Parent Application

Applicants

ORION CORPORATION

Orionintie 1 FI 02200 Espoo

Inventors

1. K??HK??NEN Marja

c/o ORION CORPORATION P.O.Box 65 FI 02101 Espoo

2. ROURU Juha

c/o ORION CORPORATION P.O.Box 65 FI 02101 Espoo

3. TAAVITSAINEN P??ivi

c/o ORION CORPORATION P.O.Box 65 FI 02101 Espoo

4. TUUNAINEN Johanna

c/o ORION CORPORATION P.O.Box 65 FI 02101 Espoo

Specification

Documents

Application Documents

#	Name	Date
1	202517033449-TRANSLATIOIN OF PRIOIRTY DOCUMENTS ETC. [04-04-2025(online)].pdf	2025-04-04
2	202517033449-STATEMENT OF UNDERTAKING (FORM 3) [04-04-2025(online)].pdf	2025-04-04
3	202517033449-REQUEST FOR EXAMINATION (FORM-18) [04-04-2025(online)].pdf	2025-04-04
4	202517033449-POWER OF AUTHORITY [04-04-2025(online)].pdf	2025-04-04
5	202517033449-NOTIFICATION OF INT. APPLN. NO. & FILING DATE (PCT-RO-105-PCT Pamphlet) [04-04-2025(online)].pdf	2025-04-04
6	202517033449-FORM 18 [04-04-2025(online)].pdf	2025-04-04
7	202517033449-FORM 1 [04-04-2025(online)].pdf	2025-04-04
8	202517033449-DRAWINGS [04-04-2025(online)].pdf	2025-04-04
9	202517033449-DECLARATION OF INVENTORSHIP (FORM 5) [04-04-2025(online)].pdf	2025-04-04
10	202517033449-COMPLETE SPECIFICATION [04-04-2025(online)].pdf	2025-04-04
11	202517033449-Proof of Right [10-07-2025(online)].pdf	2025-07-10
12	202517033449-FORM 3 [22-09-2025(online)].pdf	2025-09-22